Proceedings of Shaikh Zayed Medical Complex Lahore最新文献

{"title":"Epidemic to Pandemic: Just a Matter of Time","authors":"A. Humayun, M. I. Anwar, S. Alam, U. Iqbal","doi":"10.47489/p000s344z762mc","DOIUrl":"https://doi.org/10.47489/p000s344z762mc","url":null,"abstract":"Epidemic and pandemic potential of all respiratory diseases of zoonotic origin is well known. In recent history global public health threat was inflicted by zoonotic origin infectious diseases with pandemic potential including, Ebola and Marburg haemorrhagic fevers, severe acute respiratory syndrome (SARS), influenza A (H5N1), Middle East respiratory syndrome corona virus (MERSCoV), 1 and the recently discovered COVID-19. Change of epidemic to a pandemic is just a matter of time. A novel Corona virus 2019 (COVID-19) is appearing to be one of the rapidly transmitting diseases because of the social and economic linkages worldwide. Emerging infectious diseases (EIDs) are not new but their incidence or geographical involvement is rapidly increasing. Global temporal and spatial patterns of these emerging infections are studied well in literature concluding significant correlation of EIDs with socio-economic, environmental and ecological factors. It helps to identify regions as ‘hotspots’ for EIDs with a substantial risk of vector-borne and wildlife zoonotic emerging diseases.","PeriodicalId":20500,"journal":{"name":"Proceedings of Shaikh Zayed Medical Complex Lahore","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-03-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72668294","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Volume 33 Issue (4)","authors":"","doi":"10.47489/p000s334-z3196-1-4mc","DOIUrl":"https://doi.org/10.47489/p000s334-z3196-1-4mc","url":null,"abstract":"","PeriodicalId":20500,"journal":{"name":"Proceedings of Shaikh Zayed Medical Complex Lahore","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-12-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79361187","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Frequency of QT Interval Prolongation in Chronic Liver Disease Patients","authors":"W. Khan","doi":"10.47489/p000s334z7221-4mc","DOIUrl":"https://doi.org/10.47489/p000s334z7221-4mc","url":null,"abstract":"Introduction: The frequency of QT interval prolongation as published in the international and local literature\u0000has been variable. Aims & Objectives: To determine the frequency of QT interval prolongation in patients\u0000with chronic liver disease and resolve the variability in the literature. Place and duration of study: The\u0000present study was conducted in Gastroenterology and Hepatology Unit Shaikh Zayed Hospital Lahore from\u00001st March 2017 to 31st August 2017. Material & Methods: About 240 patients with diagnosed chronic liver\u0000disease were selected. Electrocardiography (12 lead) was performed in all patients to look for QT interval\u0000prolongation and their mean was calculated for purpose of analysis. Results: Mean age of our patients was\u000053.7±11.9 and male gender was dominant (55.8%). It was noted that QT interval was prolonged in 62 patients\u0000(25.8%) while rest of the 178 patients had normal QT interval. Conclusion: QT interval prolongation is\u0000frequently observed (25.8%) in chronic liver disease patients. Therefore, every patient with chronic liver\u0000disease should be investigated for QT interval prolongation.\u0000Key words: Chronic liver disease, QT interval, Electrocardiography","PeriodicalId":20500,"journal":{"name":"Proceedings of Shaikh Zayed Medical Complex Lahore","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-12-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75188511","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Histopathological Evaluation of GastroHepatoprotective Effect of Cassia fistula versus\u0000Naproxen in Rat Model of Rheumatoid Arthritis","authors":"Hassan Farooq","doi":"10.47489/p000s334z7241-6mc","DOIUrl":"https://doi.org/10.47489/p000s334z7241-6mc","url":null,"abstract":"Introduction: Rheumatoid arthritis (RA) is a debilitating disease leading to incapacitation and deformity due\u0000to side effects of anti arthritic drugs and chronic need to use these drugs, patients often switch to and prefer\u0000phytotherapy. Aims & Objectives: The present study was the histopathological evaluation of gastrohepatoprotective effect of Cassia fistula compared to naproxen in rheumatoid arthritis murine model. Place\u0000and duration of study: This three month study was conducted at the Animal House, University of Veterinary\u0000and Animal Sciences, Lahore. Material & Methods: Ninety six male rats were randomly sorted into 12\u0000groups (n=8). CFA injection (0.2 ml) was administered in the right hind paw of all groups except Group 1\u0000(negative control). Group 2 (positive control) and groups 3-7 (prophylactic groups) were administered orally\u0000BD on 3 consecutive days 1,2 &3, naproxen (25mg/kg), anthraquinone (250mg/kg and 500mg/kg) and\u0000methanolic (250mg/kg and 500mg/kg) extracts of Cassia fistula respectively, the first dose given 30min prior\u0000to CFA injection .Groups 8-12 (therapeutic groups) were given naproxen, anthraquinone and methanolic\u0000extracts orally BD respectively in the same doses on 3 consecutive days 9, 10 and 11. On Day 15,\u0000histopathology of stomach & liver was done. Results: Oral anthraquinone and methanolic extracts of Cassia\u0000fistula 500mg/kg vs 250mg/kg BD, in prophylactic groups normalized histology of gastric and liver tissue\u0000more as compared to the therapeutic groups and to naproxen gastrohepatic damage . Conclusion: Cassia\u0000fistula anthraquinone and methanolic extracts exhibited greater prophylactic than therapeutic, dose dependent\u0000gastrohepatoprotection as compared to naproxen damage to these organs in the CFA rheumatoid arthritis rat\u0000model.\u0000Key words: Cassia fistula, Complete Freund’s Adjuvant (CFA), naproxen, gastrohepatoprotective","PeriodicalId":20500,"journal":{"name":"Proceedings of Shaikh Zayed Medical Complex Lahore","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-12-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89540447","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of Commiphora mukul, Withania somnifera\u0000and Thyroxine on Thyroid Profile in Murine Model\u0000of Hypothyroidism","authors":"Tehreem Zulfiqar","doi":"10.47489/p000s334z7271-6mc","DOIUrl":"https://doi.org/10.47489/p000s334z7271-6mc","url":null,"abstract":"Introduction: Thyroid disorders, especially hypothyroidism are on the rise these days due to unhealthy\u0000lifestyle and nutritional deficiencies which calls for research in this domain. Monotherapy with thyroxine is\u0000considered the main line of treatment up till now but besides its beneficial role in normalizing thyroid\u0000hormone levels, it has serious cardiac effects which leads to the search of safer natural remedies. Commiphora\u0000mukul and Withanias omnifera are considered two such plants with beneficial role in correcting T3 and T4\u0000levels respectively. However keeping in mind the diagnostic importance of TSH, the effects of these phyto\u0000extracts on TSH levels needs to be established. Aims & Objectives: So the present study is designed to\u0000explore the effects of Ethanolic extract of Commiphora mukul (CMEE) and Withania somnifera (WSEE) on\u0000T3, T4 and TSH levels keeping thyroxine as a gold standard in murine model of hypothyroidism. Place and\u0000duration of study: This study was carried out in the animal house of PGMI, Lahore. Total duration of study\u0000was 38 days. Material & Methods: 50 female rats were divided into 5 groups. G-1 the control group. G-2\u0000received methimazole 60mg/kg/day for 21 days in order to induce hypothyroidism and left untreated for self\u0000recovery & G3-5 were induced with methimazole in the same way. After induction all the groups were treated\u0000for 15 days, G-3: CMEE 0.2g/kg/day orally, G4: WSEE 1.4g/kg/day orally and G-5 received the gold\u0000standard Thyroxin 0.6μg/100gm BW S/C. Thyroid function tests were performed in all groups on Day 1,\u0000repeated on Day 22 after methimazole administration and on Day 38 following completion of treatment.\u0000Results: The results showed that both CMEE and WSEE corrected T3 and T4 levels to significant extent.\u0000CMEE had more effect on T3 levels whereas WSEE corrected T4 levels more. TSH levels were also reverted\u0000to normal showing the potential of both these extracts to correct TSH besides T3, T4 levels. Conclusion: This\u0000proves that these extracts may play a significant role in correcting thyroid profile (T3, T4 & TSH) if used\u0000clinically for the treatment of hypothyroidism. However, clinical research is highly recommended in this\u0000domain.\u0000Key words: Commiphora mukul, Withania somnifera, hypothyroidism, thyroxine.","PeriodicalId":20500,"journal":{"name":"Proceedings of Shaikh Zayed Medical Complex Lahore","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-12-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81275959","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Frequency of Various Bleeding Disorders Among\u0000Gynecological and Obstetric Patients Presenting with\u0000Bleeding","authors":"Fauzia Aamer","doi":"10.47489/p000s334z7281-6mc","DOIUrl":"https://doi.org/10.47489/p000s334z7281-6mc","url":null,"abstract":"Introduction: Bleeding issues specific to women and adolescent females are common across the world.\u0000These issues can present either due to gynecological causes or obstetric one; however these can result in\u0000significant morbidity and work up needs to be done to rule out any underlying bleeding diathesis. Aims &\u0000Objectives: To determine frequency of various bleeding disorders among gynecological and obstetric patients\u0000presenting with bleeding. Place and duration of study: It is a cross sectional study which was conducted in\u0000the Hematology Department, Services Institute of Medical Sciences, Lahore. The duration of study was 6\u0000months i.e from 21st Oct, 2018 to 30th April, 2019. Material & Methods: Females with age range of 15 to 50\u0000years irrespective of pregnancy presenting as menorrhagia, metrorrhagia or obstetrical bleeding were\u0000included. Results: In the present study there were total 140 cases with mean age of 30.14±9.59 years. There\u0000were 98 (70%) cases that were pregnant. There were 35 (25%) cases presented with PPH (Post Partum\u0000Hemorrhage), 42 (30%) with IPH (Intra Partum Hemorrhage), 49 (35%) with menorrhagia and 14 (10%) with\u0000metrorrhagia. HELLP (Hemolysis, Elevated Liver enzymes and Low Platelet count) syndrome was seen in 13\u0000(9.29%) cases, DIC (Disseminated Intravascular Coagulation) in 2 (1.43%), gestational thrombocytopenia in\u00007 (5%), while factor deficiency in 34 (24.29%) cases; and 84 (60%) of cases revealed none of the bleeding\u0000disorder. Out of total 34 cases of factor deficiencies, vWD was the most common, seen in 20 (58.82%) cases.\u0000There was none of the cases seen having deficiency of factor II, VII, VIII, XI, XII. HELLP syndrome was\u0000seen in 11 (84.62%) of the cases with age group 15 to 32 years and similarly both cases of DIC were seen in\u0000same age group; but the difference in both the age groups regarding these bleeding disorders was not\u0000statistically significant with p= 0.38. There was no significant difference in terms of pregnancy; however,\u0000both cases of DIC were seen in pregnancy with insignificant p value of 0.51. HELLP syndrome was more\u0000seen in IPH affecting 5 (38.40%), factor deficiency in menorrhagia affecting 13 (38.2%) with p value of 0.61.\u0000vWD and factor V Leiden presented in 44.4% cases each with PPH, and vWD affected 87.5% of cases in IPH\u0000without any significant difference with p= 0.42. Conclusion: Bleeding disorders are not uncommon in\u0000gynecological and obstetric conditions. Factor deficiency were the most common causes and amongst these\u0000vWD was the most deficient factor. There was no significant association with any confounding variable;\u0000however, DIC was only seen in obstetrical conditions.\u0000Key words: Bleeding, menorrhagia, HELLP, DIC, IPH, PPH","PeriodicalId":20500,"journal":{"name":"Proceedings of Shaikh Zayed Medical Complex Lahore","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-12-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81784029","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Frequency of Mucocutaneous Manifestations of Asthma in Paediatric Patients Aged 2-14 Years","authors":"Lubna Riaz","doi":"10.47489/p000s334z7251-5mc","DOIUrl":"https://doi.org/10.47489/p000s334z7251-5mc","url":null,"abstract":"<jats:p>.</jats:p>","PeriodicalId":20500,"journal":{"name":"Proceedings of Shaikh Zayed Medical Complex Lahore","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-12-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80373183","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An Update on Isolation of Extensively Drug Resistant\u0000(XDR) Salmonella enterica from Blood Cultures in a\u0000Tertiary Care Centre","authors":"S. Hameed","doi":"10.47489/p000s334z7261-5mc","DOIUrl":"https://doi.org/10.47489/p000s334z7261-5mc","url":null,"abstract":"Introduction: Typhoid fever is a public health issue, burdening many regions of the world with poor socioeconomic background. Management of this disease faces the major hurdle of antimicrobial resistance. The\u0000present study reveals current pattern of antimicrobial susceptibility among Salmonella enterica (Salmonella\u0000typhi & Salmonella paratyphi A) blood culture isolates from typhoid fever cases. Regular data collection\u0000about Salmonella infections and their response to antimicrobial agents, coupled with a long term commitment\u0000to providing adequate health information systems, is the key to effective planning and policy formation\u0000against typhoid fever. Aims & Objectives: To evaluate the prevalence of ceftriaxone resistant Salmonella\u0000enterica isolates from blood cultures in Shaikh Zayed Medical Complex for updating nosocomial\u0000antimicrobial resistance data. Place and duration of study: This research study was conducted at Shaikh\u0000Zayed Medical Complex, Lahore from March 2018 to May 2019. Material & Methods: Blood cultures\u0000positive for Salmonella enterica were analyzed, taking into consideration the gender & age of patients with\u0000typhoid fever. Antimicrobial susceptibility testing was carried out through disc diffusion method. The\u0000recommended antimicrobial agents for S. typhi (Salmonella typhi) & S. paratyphi A (Salmonella Parathyphi\u0000A) (as per CLSI, USA 2018/2019 guidelines; described later), were tested and analyzed during this study with\u0000the main focus on 3rd generation cephalosporin resistance pattern. Among second line treatment options,\u0000meropenem and azithromycin were selected for study. Results: Out of 899 isolates of Salmonella enterica\u0000(from 13964 samples for blood culture), 849 (94.4%) were S. typhi and 50 (5.6%) were S. paratyphi A. Of\u0000these, 57.1% isolates were from males, 42.9% from females, 81.7% from children (age less than 12 years) and\u000018.3% were from adults (age more than 12 years). A continuously rising resistance percentage was observed\u0000for 3rd generation cephalosporins over the span of fifteen months. It was 43.4% for ceftriaxone (CRO). No\u0000case of meropenem and azithromycin resistance was observed during study period. Conclusion:\u0000Demographic information was provided by this study regarding high level of resistance among Salmonella\u0000enterica isolates particularly S. typhi .The first line antibiotic drugs were a complete failure in ongoing\u0000outbreak of typhoid fever. The novel results of this study are the high resistance percentages for 3rd generation\u0000cehalosporins, whether oral or parenteral. This result is worrisome as it will leave us with no option but to\u0000resort to second line drugs. However, an increasing trend of blood culturing was observed in this research.\u0000Extensively drug resistant (XDR) Salmonella infection has definitely highlighted the importance of blood\u0000culture and its use as a more preferred diagnostic tool.\u0000Key words: Typhoid fever, Extensively drug resistant (XDR) Salmonella enterica, (S. typhi & S. paratyphi\u0000A), Antimi","PeriodicalId":20500,"journal":{"name":"Proceedings of Shaikh Zayed Medical Complex Lahore","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-12-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85078125","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hepatoprotective Effect of Ajwa Date Seed and\u0000Simvastatin in Non Alcoholic Fatty Liver Disease\u0000(NAFLD) Murine Model of Butter Fed Dyslipidemia","authors":"Farooq Sultan","doi":"10.47489/p000s334z7291-6mc","DOIUrl":"https://doi.org/10.47489/p000s334z7291-6mc","url":null,"abstract":"Introduction: Non-alcoholic fatty liver disease (NAFLD) is a dangerous complication of hyperlipidemia\u0000which may lead to life threatening hepatitis and hepatic cirrhosis. Internationally, Prevalence of non-alcoholic\u0000fatty liver disease (NAFLD) is 20% in general population while 75% in the obese population of USA.1 Side\u0000effects of allopathic drugs have led the research towards natural products to find out their potential for\u0000treatment of NAFLD. Aims & Objectives: Aim of this study was evaluation of hepatoprotective effects of\u0000Ajwa date seed and Simvastatin against NAFLD. Place and duration of study: Study was conducted at\u0000animal house of UHS, Lahore and completed in 6 months. Material & Methods: 40 rats were procured and\u0000segregated into 5 groups with 8 rats in each group. Group 1 was healthy control and group 2 was disease\u0000control. Group 3, 4 and 5 were administered Simvastatin 10mg/kg/day, aqueous Ajwa date seed extract\u0000(ADSE) 8ml/kg/day and combination of Simvastatin 5mg/kg/day and aqueous ADSE 4ml/kg/day\u0000respectively. Total study duration was 36 days. First 15 days were for induction of hyperlipidemia while\u0000treatment was given for remaining 21 days. Serum total cholesterol (TC), triglycerides (TG) and liver\u0000functions tests (Serum ALT, AST and ALP) were performed at day 0, 15 and 36 of study. Data was entered\u0000on SPSS 23.0 software and analyzed by one way ANOVA and post hoc tuckey’s tests. P-value of less than\u00000.05 was considered significant. Results: Aqueous Ajwa date seed extract (ADSE), Simvastatin and their\u0000combination showed significant TC and TG lowering and hepatoprotective effects against NAFLD. However,\u0000individual drugs were more effective than the combination. Conclusion: Ajwa date seed can be used for the\u0000treatment of NAFLD.\u0000Key words: Ajwa date seed, Hyperlipidemia, Simvastatin","PeriodicalId":20500,"journal":{"name":"Proceedings of Shaikh Zayed Medical Complex Lahore","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-12-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72547678","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of Renal Function Parameters in\u0000Normotensive and Pre-Eclamptic Pregnant Women at\u0000Different Stages of Pregnancy","authors":"Farhana Mukhtar","doi":"10.47489/p000s334z7231-4mc","DOIUrl":"https://doi.org/10.47489/p000s334z7231-4mc","url":null,"abstract":"Introduction: Pre-eclampsia is one of the most common causes of maternal and fetal complications in developing countries. Owing to its multisystem involvement, hypertension and proteinuria in pre-eclamptic women may lead to acute or chronic renal failure. Early diagnosis is vital to avoid this organ failure. Aims & Objectives: To assess renal function by measuring and comparing four renal function parameters including Blood urea Nitrogen (BUN),serum creatinine, creatinine clearance and 24-hr urinary protein in pre-eclamptic and normotensive pregnant women at different stages of pregnancy. Place and duration of study: This prospective and observational study was conducted in 2009 at Shaikh Zayed Hospital. The patients were taken from Gynae and Obstetrics OPD, with 24 weeks of gestation. Material & Methods: In this study, 25 normotensive Controls and 25 pre-eclamptic pregnant women (cases) were included. Serum and urinary samples were taken at 24 weeks, 28 weeks, 32 weeks of gestation as well as at term (38 weeks). Blood urea nitrogen (BUN), serum creatinine, spot urinary protein and urinary creatinine were measured by clinical Chemistry Auto analyzer Dimension AR. Whereas, 24 hours urinary protein and creatinine clearance were calculated later. Results: BUN level of cases were significantly high as compared to controls at 32 weeks and at term (p<0.01) however creatinine clearance was found to be significantly low (p>0.05) in pre-elamptic women only at 38 weeks. Apart from other results, 24-hours urinary protein was found to be significantly high (p<0.05) in pre-eclamptic women as compared to normotensive women at all stages of pregnancy. Conclusion: Our study showed that BUN, Creatinine clearance and most importantly 24-hr urinary protein may be used to assess the renal function in relation with the severity of pre-eclampsia. Key words: Pre-eclampsia, Blood Urea Nitrogen (BUN), Proteinuria.","PeriodicalId":20500,"journal":{"name":"Proceedings of Shaikh Zayed Medical Complex Lahore","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-12-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89743575","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}