{"title":"[Ultrasound-guided synovial biopsy].","authors":"Mauro Bachmann, Katharina Zachariassen, Chantal Pauli, Nina Colla, Oliver Distler, Raphael Micheroli","doi":"10.23785/PRAXIS.2024.11.006","DOIUrl":"https://doi.org/10.23785/PRAXIS.2024.11.006","url":null,"abstract":"<p><strong>Introduction: </strong>A 47-year-old female presented with arthritis in the left hand's PIP III. Her symptoms were negative for connective tissue disease or spondyloarthritis, but she had HIV and hepatitis B. Initial tests showed no systemic inflammation or abnormal antibodies, and radiology revealed no bony changes. Despite a successful initial treatment with a Kenacort injection, arthritis recurred in both hands. A synovial biopsy via ultrasound revealed gout tophi, confirmed by dual-energy CT showing urate crystals in the soft tissue. Synovial biopsy is an effective, minimally invasive diagnostic tool for undifferentiated arthritis when other tests are inconclusive. Though puncture analysis remains the gold standard, it was not possible in this case due to lack of joint effusion.</p>","PeriodicalId":20494,"journal":{"name":"Praxis","volume":"113 11-12","pages":"318-320"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142855036","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
PraxisPub Date : 2024-12-01DOI: 10.23785/PRAXIS.2024.11.007
Alexandra Schaeren, Johannes Nemeth, Bertram Feil, Benjamin Preiswerk
{"title":"[XDR tuberculosis, a challenge not just from a medical point of view].","authors":"Alexandra Schaeren, Johannes Nemeth, Bertram Feil, Benjamin Preiswerk","doi":"10.23785/PRAXIS.2024.11.007","DOIUrl":"10.23785/PRAXIS.2024.11.007","url":null,"abstract":"<p><strong>Introduction: </strong>A young patient from Georgia presented with pulmonary XDR-tuberculosis after months of failed treatment in his home country. Based on genotypic examinations of the sputum samples and a Georgian antibiogram the diagnosis was confirmed and an empirical treatment was started. Despite many initial uncertainties and severe side effects over the course of the treatment, for which treatment adjustments were necessary, the therapy was succesfull with clear clinical and radiological response.</p>","PeriodicalId":20494,"journal":{"name":"Praxis","volume":"113 11-12","pages":"321-324"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142855043","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
PraxisPub Date : 2024-12-01DOI: 10.23785/PRAXIS.2024.11.001
Thomas Rosemann
{"title":"Diät wirksamer auf Körpergewicht und HbA1c als Metformin und SGLT-2-Hemmer.","authors":"Thomas Rosemann","doi":"10.23785/PRAXIS.2024.11.001","DOIUrl":"10.23785/PRAXIS.2024.11.001","url":null,"abstract":"<p><strong>Introduction: </strong></p>","PeriodicalId":20494,"journal":{"name":"Praxis","volume":"113 11-12","pages":"292"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142855047","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
PraxisPub Date : 2024-12-01DOI: 10.23785/PRAXIS.2024.11.002
Rafael Meyer, Andreas Monsch, Gilles Allali, Nadège Barro-Belaygues, Stefanie Becker, Markus Bürge, Giovanni B Frisoni, Dan Georgescu, Anton Gietl, Hans H Jung, Aurelien Lathuiliere, Kathrin Lindheimer, Karl-Olof Lovblad, Tatjana Meyer-Heim, Julius Popp, Olivier Rouaud, Marc Sollberger, Ansgar Felbecker
{"title":"[Alzheimer's disease - system prepardeness in the context of new developments].","authors":"Rafael Meyer, Andreas Monsch, Gilles Allali, Nadège Barro-Belaygues, Stefanie Becker, Markus Bürge, Giovanni B Frisoni, Dan Georgescu, Anton Gietl, Hans H Jung, Aurelien Lathuiliere, Kathrin Lindheimer, Karl-Olof Lovblad, Tatjana Meyer-Heim, Julius Popp, Olivier Rouaud, Marc Sollberger, Ansgar Felbecker","doi":"10.23785/PRAXIS.2024.11.002","DOIUrl":"https://doi.org/10.23785/PRAXIS.2024.11.002","url":null,"abstract":"<p><strong>Introduction: </strong>The possible authorisation of new monoclonal antibody therapies for Alzheimer's disease poses challenges for healthcare systems worldwide. In this paper, the Swiss Memory Clinics association (SMC) analyses the available resources and identifies potential health care shortages. Overcoming potential bottlenecks is a challenge that requires action at various levels. However, our analysis also shows that we are well positioned in Switzerland to integrate new developments into existing care structures.</p>","PeriodicalId":20494,"journal":{"name":"Praxis","volume":"113 11-12","pages":"293-296"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142854906","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
PraxisPub Date : 2024-12-01DOI: 10.23785/PRAXIS.2024.11.005
Gioia Buschta, Luca Regli, Julia Velz
{"title":"[Clinical management of patients with cavernous malformations of the central nervous system: an update and recommendations for clinical practice].","authors":"Gioia Buschta, Luca Regli, Julia Velz","doi":"10.23785/PRAXIS.2024.11.005","DOIUrl":"https://doi.org/10.23785/PRAXIS.2024.11.005","url":null,"abstract":"<p><strong>Introduction: </strong>Cerebral cavernous malformations are benign vascular anomalies of the central nervous system (CNS). The clinical presentation of a cavernoma depends on its location. The majority of patients with cavernomas are asymptomatic. The most common symptoms include epileptic seizures, focal neurological deficits and/or headaches. The clinical management of cavernomas is challenging because numerous factors influence decision-making. These factors include the risk stratification of cavernoma-related hemorrhage, weighing the risks of surgical intervention against the natural course of the cavernoma and the clinical presentation. This article presents current guidelines and recommendations for clinical practice, based on the latest research findings and expert opinions. The article focuses on diagnostic approaches, risk stratification, therapeutic management and follow-up strategies.</p>","PeriodicalId":20494,"journal":{"name":"Praxis","volume":"113 11-12","pages":"313-317"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142854980","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
PraxisPub Date : 2024-11-01DOI: 10.23785/PRAXIS.2024.10.001
Thomas Rosemann, Andrea Rosemann
{"title":"Sport-Paradox – Intensiver Sport erhöht das Risiko, eine relevante Koronarstenose zu entwickeln.","authors":"Thomas Rosemann, Andrea Rosemann","doi":"10.23785/PRAXIS.2024.10.001","DOIUrl":"10.23785/PRAXIS.2024.10.001","url":null,"abstract":"<p><strong>Introduction: </strong></p>","PeriodicalId":20494,"journal":{"name":"Praxis","volume":"113 10","pages":"250-251"},"PeriodicalIF":0.0,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142813948","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
PraxisPub Date : 2024-11-01DOI: 10.23785/PRAXIS.2024.10.008
Iris Neto, Cristian Camartin
{"title":"[Anti-Hu syndrome - an unusual cause of vertigo].","authors":"Iris Neto, Cristian Camartin","doi":"10.23785/PRAXIS.2024.10.008","DOIUrl":"10.23785/PRAXIS.2024.10.008","url":null,"abstract":"<p><strong>Introduction: </strong>On the palliative care ward, we treated a man with a small cell lung cancer who was suffering from vertigo for six years, however the vertigo got stronger the last six months with pronounced coordination disorders. After several examinations, the cause was a paraneoplastic neurologic syndrome (PNS) with Hu-antibodies. PNS are various neurological malfunctions, which occur mostly in certain patterns. The pathogenesis is immune-mediated through a tumor. This is the reason why the treatment of the PNS is within the treatment of the tumor.</p>","PeriodicalId":20494,"journal":{"name":"Praxis","volume":"113 10","pages":"280-282"},"PeriodicalIF":0.0,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142813979","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
PraxisPub Date : 2024-11-01DOI: 10.23785/PRAXIS.2024.10.002
Thomas Rosemann
{"title":"Die Einnahme von Multivitaminpräparaten ist ohne Einfluss auf die Mortalität.","authors":"Thomas Rosemann","doi":"10.23785/PRAXIS.2024.10.002","DOIUrl":"https://doi.org/10.23785/PRAXIS.2024.10.002","url":null,"abstract":"<p><strong>Introduction: </strong></p>","PeriodicalId":20494,"journal":{"name":"Praxis","volume":"113 10","pages":"252"},"PeriodicalIF":0.0,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142813944","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
PraxisPub Date : 2024-11-01DOI: 10.23785/PRAXIS.2024.10.009
Bernhard Morell, Stephan Ullrich, Stefan Gutknecht, Pascal Weibel, Jörg Wydler, Christoph Gubler
{"title":"[Pancreatic cystic neoplasms: work-up and surveillance].","authors":"Bernhard Morell, Stephan Ullrich, Stefan Gutknecht, Pascal Weibel, Jörg Wydler, Christoph Gubler","doi":"10.23785/PRAXIS.2024.10.009","DOIUrl":"10.23785/PRAXIS.2024.10.009","url":null,"abstract":"<p><strong>Introduction: </strong>Whereas pancreatic masses are often difficult to detect with transabdominal ultrasound, cross-sectional imaging features high sensitivity for the pancreatic tumors. However, increasing availability of magnetic resonance imaging (MRI) has led to a surge in the detection of benign or precancerous pancreatic lesions. The medical history is characteristic only for two entities. A history of acute or chronic pancreatitis favors a benign pseudocyst while weight loss or jaundice are suggestive of malignancy. More challenging is the classification of asymptomatic cysts, which often require extensive work-up and, in advanced stages, pancreatic resection. In case of overdiagnosis and overtreatment, this is also referred to as VOMIT: victims of modern imaging technology (1). On the other hand, it is important to identify precancerous lesions that should be monitored with the aim of timely recognizing progression towards invasive cancer. The aim of this overview is to focus on incidentally detected pancreatic cystic lesions with a description of the investigations and surveillance. Pancreatic cancer and pseudocysts are beyond the scope of this review. However, the latter are discussed in terms of differential diagnoses, as pseudocysts are occasionally found by chance in everyday clinical practice, but should not be monitored.</p>","PeriodicalId":20494,"journal":{"name":"Praxis","volume":"113 10","pages":"283-288"},"PeriodicalIF":0.0,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142813975","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}