PraxisPub Date : 2025-10-01DOI: 10.23785/PRAXIS.2025.10.006
Jonas Gysel, Stephan Steuer, Mario Kurz
{"title":"[The infectious liver tumour].","authors":"Jonas Gysel, Stephan Steuer, Mario Kurz","doi":"10.23785/PRAXIS.2025.10.006","DOIUrl":"10.23785/PRAXIS.2025.10.006","url":null,"abstract":"<p><strong>Introduction: </strong>Alveolar echinococcosis remains a rare parasitic disease, but the number of cases in Western Europe is increasing. Diagnosis is difficult due to a long incubation period and non-specific symptoms. Curative treatment can only be achieved through R0 resection. Suppressive therapy with albendazole can now achieve good long-term survival even in cases where surgery is not possible.</p>","PeriodicalId":20494,"journal":{"name":"Praxis","volume":"114 10","pages":"368-371"},"PeriodicalIF":0.0,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145725686","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
PraxisPub Date : 2025-10-01DOI: 10.23785/PRAXIS.2025.10.007
Nathalie Mayor, Moritz Strickler, Susanna Frigerio, Ferdinand von Bredow
{"title":"[51-Year-old Patient With Word Finding Difficulties].","authors":"Nathalie Mayor, Moritz Strickler, Susanna Frigerio, Ferdinand von Bredow","doi":"10.23785/PRAXIS.2025.10.007","DOIUrl":"10.23785/PRAXIS.2025.10.007","url":null,"abstract":"<p><strong>Introduction: </strong>A 51-year-old patient presented to the Memory Clinic with difficulty finding words that had been increasing over the course of months. This could not be objectified in the anamnesis interview, but the CERAD test battery revealed slight abnormalities in naming and verbal memory. MR tomography showed discrete hippocampal hypotrophy on the right. Because depression existed at the same time, the symptoms were associated with this, especially since the symptoms also improved with treatment of the depression. Only further MR tomographic imaging and FDG-PET, as well as questioning of handedness, finally led to the diagnosis of semantic dementia.</p>","PeriodicalId":20494,"journal":{"name":"Praxis","volume":"114 10","pages":"372-374"},"PeriodicalIF":0.0,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145725553","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
PraxisPub Date : 2025-10-01DOI: 10.23785/PRAXIS.2025.10.008
Andrea Rosemann, Thomas Rosemann
{"title":"Vorhofflimmern: Frühe Rhythmuskontrolle auch bei Adipositas und Typ-2-Diabetes indiziert.","authors":"Andrea Rosemann, Thomas Rosemann","doi":"10.23785/PRAXIS.2025.10.008","DOIUrl":"https://doi.org/10.23785/PRAXIS.2025.10.008","url":null,"abstract":"<p><strong>Introduction: </strong></p>","PeriodicalId":20494,"journal":{"name":"Praxis","volume":"114 10","pages":"375"},"PeriodicalIF":0.0,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145725607","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
PraxisPub Date : 2025-10-01DOI: 10.23785/PRAXIS.2025.10.001
Selina Widmer, Samuel Stähelin, Andreas Zeller, Roland Fischer
{"title":"[Preoperative Testing in Ophthalmic surgery - Adherence to Guidelines in Northwestern and Central Switzerland].","authors":"Selina Widmer, Samuel Stähelin, Andreas Zeller, Roland Fischer","doi":"10.23785/PRAXIS.2025.10.001","DOIUrl":"https://doi.org/10.23785/PRAXIS.2025.10.001","url":null,"abstract":"<p><strong>Introduction: </strong>In Switzerland, patients are referred to their GP for preoperative examinations before cataract surgery. However, according to the ESC Guideline 2022, this is unnecessary. The aim of this study was to assess guideline adherence for preoperative assessment prior to cataract surgery in Northwestern and Central Switzerland. All licensed ophthalmic surgeons were identified via public registers. They were contacted and asked for the preoperative GP form. These forms were then compared to recommendations. Only two of five categories showed a majority of adherence to the guideline. There was no significant difference between regions. Preoperative examinations lead to avoidable workload, additional costs and unnecessary patient examinations.</p>","PeriodicalId":20494,"journal":{"name":"Praxis","volume":"114 10","pages":"344-348"},"PeriodicalIF":0.0,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145725691","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
PraxisPub Date : 2025-10-01DOI: 10.23785/PRAXIS.2025.10.003
Hannah Vera Schmieg, Emmanuel Baierlé, Beat Müller
{"title":"[The difficulty of pain-assessment in palliative care ESAS and MIDOS - measuring instruments with limited informative value].","authors":"Hannah Vera Schmieg, Emmanuel Baierlé, Beat Müller","doi":"10.23785/PRAXIS.2025.10.003","DOIUrl":"10.23785/PRAXIS.2025.10.003","url":null,"abstract":"<p><strong>Introduction: </strong>Palliative care provides care for seriously ill and dying people, often suffering from pain. Adequate pain treatment is therefore a main focus of the treatment team. Attempts are made to objectify the occurrence of pain using scoring systems such as ESAS or MIDOS. However, the difficulty of objectifying subjective conditions, such as the phenomenon of pain, is problematic and renders the scoring systems poor in content. Only through the complementary efforts of the treatment team, which can be found in the basic attitude of an open-minded recognition of states of suffering, can the best possible approximation to what can be understood as an intersubjective objectification of the pain event be achieved and ultimately the symptom burden be better reduced. However, without negating the difficulties that arise with the objectification of pain.</p>","PeriodicalId":20494,"journal":{"name":"Praxis","volume":"114 10","pages":"356-359"},"PeriodicalIF":0.0,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145725681","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
PraxisPub Date : 2025-10-01DOI: 10.23785/PRAXIS.2025.10.004
Julia Inglin, Aurora Muff, Dominique Oberlin, Reto Nüesch
{"title":"[Generalised exanthema with abdominal sepsis].","authors":"Julia Inglin, Aurora Muff, Dominique Oberlin, Reto Nüesch","doi":"10.23785/PRAXIS.2025.10.004","DOIUrl":"10.23785/PRAXIS.2025.10.004","url":null,"abstract":"<p><strong>Introduction: </strong>We present the case of a 53-year-old patient who developed DRESS syndrome with hepatopathy and sepsis-like symptoms, including the need for vasoactive agents, while receiving antibiotic therapy. In this report, we show the diagnostic process from the initially suspected and frequent abdominal sepsis to the rare DRESS syndrome. Only after discontinuation of the antibiotic therapy and initiation of steroids did the condition gradually improve.</p>","PeriodicalId":20494,"journal":{"name":"Praxis","volume":"114 10","pages":"360-363"},"PeriodicalIF":0.0,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145725601","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
PraxisPub Date : 2025-10-01DOI: 10.23785/PRAXIS.2025.10.002
Nadia Exquis, Gabriel Gold, Enos Bernasconi, Tanja Fusi-Schmidhauser
{"title":"[How Do Older People Perceive Deprescribing? A systematic integrative literature review].","authors":"Nadia Exquis, Gabriel Gold, Enos Bernasconi, Tanja Fusi-Schmidhauser","doi":"10.23785/PRAXIS.2025.10.002","DOIUrl":"https://doi.org/10.23785/PRAXIS.2025.10.002","url":null,"abstract":"<p><strong>Introduction: </strong>Ageing of the general population is a major forthcoming challenge for all healthcare systems. Co-morbidities in geriatrics lead to the prescription of complex polymedications. Deprescribing is a decision-making process that limits the number of inappropriate drugs. Nevertheless, the patient's perspective remains insufficiently studied. An extensive literature search of several databases identified nine studies up to May 2024 that met the criteria for inclusion. Four main themes have been identified around patients' perception of deprescription: 1) the relationship with the general practitioner, 2) the clinical aspects, 3) the psychosocial dimension and 4) the practical aspects. Several factors facilitating deprescribing from the patient's perspective have been identified and can be exploited clinically.</p>","PeriodicalId":20494,"journal":{"name":"Praxis","volume":"114 10","pages":"349-355"},"PeriodicalIF":0.0,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145725652","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
PraxisPub Date : 2025-09-01DOI: 10.23785/PRAXIS.2025.08_09.005
Raffaele Piazza, Katja Weiss, Thomas Rosemann, Beat Knechtle
{"title":"[Fluoroquinolone-associated disability after taking ciprofloxacin].","authors":"Raffaele Piazza, Katja Weiss, Thomas Rosemann, Beat Knechtle","doi":"10.23785/PRAXIS.2025.08_09.005","DOIUrl":"https://doi.org/10.23785/PRAXIS.2025.08_09.005","url":null,"abstract":"<p><strong>Introduction: </strong>Ciprofloxacin is among the most commonly prescribed Fluoroquinolones. Side effects of Fluoroquinolones include tendinopathies, ar-rhythmias, gastrointestinal discomfort, and neurological symptoms. The definition of a \"Fluoroquinolone-associated disability\" includes dis-ability, symptoms in several body systems and duration of symptoms after discontinuation of the antibiotic. The pathophysiology of this disease is probably due to a damage to the redox system. We report on a 41-year-old patient who felt pain in his Achilles tendons three days after starting to take ciprofloxacin (of a total of 3 g) and presented as an emergency. In the course of the disease, the pain became chronically disabling and the patient developed paresthesia of both extremities and intermittent heart palpitations. The only tolerated pain medication was Pregabalin. Several MRI examinations showed minimal peritendinitis and irritation of the Achilles tendons. Blood samples indicated probable intracellular damage at low intracellular ATP and coenzyme Q10 values.</p>","PeriodicalId":20494,"journal":{"name":"Praxis","volume":"114 8-9","pages":"326-330"},"PeriodicalIF":0.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145186608","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
PraxisPub Date : 2025-09-01DOI: 10.23785/PRAXIS.2025.08_09.003
Helen Slawik, Jens G Acker, Christine Blume, Anna Castelnovo, Katerina Espa Cervena, Miriam Gerstenberg, Elisabeth Hertenstein, Christian Imboden, Thorsten Mikoteit, Christian Mikutta, Lampros Perogamvros, Tifenn Raffray, Carolin Reichert, Verena Reiss, Carlotta L Schneider, Steffi Weidt, Cristina Zunzunegui, Martin Hatzinger, Christoph Nissen, Dagmar A Schmid
{"title":"[Treatment recommendations for chronic insomnia - cognitive behavioural therapy as first-line treatment].","authors":"Helen Slawik, Jens G Acker, Christine Blume, Anna Castelnovo, Katerina Espa Cervena, Miriam Gerstenberg, Elisabeth Hertenstein, Christian Imboden, Thorsten Mikoteit, Christian Mikutta, Lampros Perogamvros, Tifenn Raffray, Carolin Reichert, Verena Reiss, Carlotta L Schneider, Steffi Weidt, Cristina Zunzunegui, Martin Hatzinger, Christoph Nissen, Dagmar A Schmid","doi":"10.23785/PRAXIS.2025.08_09.003","DOIUrl":"10.23785/PRAXIS.2025.08_09.003","url":null,"abstract":"<p><strong>Introduction: </strong>In addition to the treatment recommendations published by the Special Interest Group (SIG) \"Mental Health\" (formerly \"Sleep Psychiatry\") of the Swiss Society for Sleep Research, Sleep Medicine and Chronobiology (SGSSC), the following article focusses on cognitive behavioural therapy for insomnia (CBT-I), its evidence, implementation and application, including in shift work, patients on medication, older people, various formats and non-pharmacological alternatives. Chronic insomnia is a disorder characterised by hyperarousal rather than sleep deprivation. The most effective treatment is bedtime restriction. This can be accompanied by increased daytime sleepiness and concentration deficits, which can be challenging. Furthermore, it is a challenge to find activities for the time that becomes available. The number of therapy places is still insufficient. However, it has been shown that CBT-I is also effective in shortened formats, digitally or when carried out by other professional groups.</p>","PeriodicalId":20494,"journal":{"name":"Praxis","volume":"114 8-9","pages":"313-320"},"PeriodicalIF":0.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145186545","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
PraxisPub Date : 2025-09-01DOI: 10.23785/PRAXIS.2025.08_09.006
Ava Bode, Myriam Wyss Fopp, Jean-Luc Kurzen
{"title":"[Severe phototoxic side effects of pirfenidone].","authors":"Ava Bode, Myriam Wyss Fopp, Jean-Luc Kurzen","doi":"10.23785/PRAXIS.2025.08_09.006","DOIUrl":"10.23785/PRAXIS.2025.08_09.006","url":null,"abstract":"<p><strong>Introduction: </strong>This case report describes a phototoxic drug reaction in an 81-year-old patient taking the antifibrotic drug pirfenidone for the treatment of idiopathic pulmonary fibrosis. After two hours of sun exposure with sunscreen (SPF 50), the patient developed pruritic, erythematous and scaly lesions on the sun-exposed areas (face, neck, hands and forearms). Physical examination revealed an erythematous exanthema with coarse lamellar scale. A phototoxic reaction to pirfenidone was suspected based on the clinical presentation and distribution pattern. Treatment with topical corticosteroids and discontinuation of pirfenidone led to a marked improvement in symptoms. This case highlights the potential phototoxic risks of pirfenidone, which should be considered especially in dermatological practice where the drug is less known. In addition, important differential diagnoses are outlined and discussed.</p>","PeriodicalId":20494,"journal":{"name":"Praxis","volume":"114 8-9","pages":"331-333"},"PeriodicalIF":0.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145186568","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}