V V Erokhin, V P Chukanova, I E Fedorova, L I Zueva
{"title":"[History of the setting up of the research museum of the Central Research Institute of Tuberculosis, Russian Academy of Medical Sciences].","authors":"V V Erokhin, V P Chukanova, I E Fedorova, L I Zueva","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":20490,"journal":{"name":"Problemy tuberkuleza","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2002-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"22268337","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
B P Bubochkin, V R Teslenko, V V Okhtiarkina, M V Lekhliaĭder
{"title":"[A sociomedical portrait of tuberculosis control service workers].","authors":"B P Bubochkin, V R Teslenko, V V Okhtiarkina, M V Lekhliaĭder","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The social and medical causes of occupational tuberculosis were analyzed by using the results of questionnaire surveys in 300 workers of tuberculosis controlling service. Low salaries, high working load, unbalanced nutrition, poor rehabilitation on vacation are the most important risk factors leading to high rates of both somatic and occupational morbidity in the staff of antituberculosis service.</p>","PeriodicalId":20490,"journal":{"name":"Problemy tuberkuleza","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2002-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"22171602","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
V S Golanov, O V Bukharin, B Ia Usviatsov, S A Seliukova
{"title":"[Prognostic value of isolation of L-forms of Mycobacterium tuberculosis].","authors":"V S Golanov, O V Bukharin, B Ia Usviatsov, S A Seliukova","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>A procedure has been developed to detect antilysozymatic activity n L forms of Mycobacterium tuberculosis (MBT). A mode of predicting the course of a tuberculosis process in the lungs by the degree of antilysozymatic activity of MBT is outlined. Thus, when the level is 4 micrograms/ml or higher, progression or exacerbation of tuberculosis is predicted, when that of 0-3 micrograms/ml, a good prognosis is expected.</p>","PeriodicalId":20490,"journal":{"name":"Problemy tuberkuleza","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2002-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"22172782","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M V Pavlova, L A Ivanova, O T Titarenko, M E D'iakova
{"title":"[Characteristics of endogenous intoxication of adolescents with tuberculosis].","authors":"M V Pavlova, L A Ivanova, O T Titarenko, M E D'iakova","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The paper shows that there is an association of the pattern of lung lesion with the endogenous intoxication in adolescents patients with pulmonary tuberculosis. Based on the spectrograms of plasma and the levels of low and medium molecular-weight substances, the authors revealed clinical features in relation to the level of endogenous intoxication and to the values of cellular responses.</p>","PeriodicalId":20490,"journal":{"name":"Problemy tuberkuleza","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2002-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"22192190","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Regional tuberculosis morbidity in the Russian Federation (2000-2001)].","authors":"","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":20490,"journal":{"name":"Problemy tuberkuleza","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2002-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"22192318","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Iron metabolism in patients with different variants of pulmonary tuberculosis].","authors":"G O Kaminskaia, R Iu Abdullaev","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Prior to treatment, 48 patients with different forms of pulmonary tuberculosis were examined. Serum iron concentrations, total iron-binding capacity of the serum (STIBC), its unsaturated iron-binding capacity (SUSIB), serum transferrin iron saturation coefficient (SC), total protein in the serum, red blood cells, hemoglobin, colour index were determined. All the parameters under study were in the normal range in patients with a favourable involutional course of pulmonary tuberculosis. In patients with acutely progressive pulmonary tuberculosis, serum iron levels, STIBC, SC were drastically decreased, while SUSIB was in the normal range. All this was attended by phenomena of hypochromic anemia. The pattern of the found changes leads to the conclusion that patients with acutely progressive tuberculosis develop iron-redistributing anemia caused by the changes in the amount and quality of transferrin, iron binding during free radical processes and mobilization of the antioxidant defense system rather than true iron deficiency.</p>","PeriodicalId":20490,"journal":{"name":"Problemy tuberkuleza","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2002-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"22268333","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
V S Sokolova, V P Strel'tsov, E A Talambum, T I Ivanova, L N Novikova
{"title":"[Methods of functional rehabilitation of patients after lung surgery].","authors":"V S Sokolova, V P Strel'tsov, E A Talambum, T I Ivanova, L N Novikova","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":20490,"journal":{"name":"Problemy tuberkuleza","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2002-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"22251252","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Efficacy of treatment for pulmonary tuberculosis with multidrug mycobacterial resistance].","authors":"V Iu Mishin, V I Chukanov, I A Vasil'eva","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The efficiency of treatment was studied in 149 patients with pulmonary tuberculosis who isolated multidrug resistance of Mycobacteria tuberculosis (MBT). The multidrug resistance of MTB, to at least isoniazid and rifampicin can be associated with both the resistance to other essential (streptomycin, ethambutol) and that to reserve drugs. With this, patients with MBT resistance to a combination of essential and reserve drugs more frequently showed a chronic course of the disease with severe clinical manifestations and more disseminated infiltrative-and-destructive lesions in the lung. Drug treatment regimens using a combination of reserve drug were effective only in patients with MBT resistance to essential drugs while they were little effective in those with resistance to essential and reserve agents. The use of artificial pneumothorax in patients with MBT resistance to essential and reserve agents could cease bacterial isolation in 77.8% of the patients even by ingesting a small number of the drugs. Clinically, the occurrence of MBT resistance to reserve drugs is justified to determine a radically new status in patients in the context of chemotherapy and the whole further treatment in this group of patients. A clinical classification of MBT multidrug resistance is proposed, which identifies two categories of patients with pulmonary tuberculosis: those resistant to essential drugs and those resistant to a combination of essential and reserve drugs.</p>","PeriodicalId":20490,"journal":{"name":"Problemy tuberkuleza","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2002-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"22267813","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Diagnosis and treatment of extrapulmonary tuberculosis].","authors":"Sung‐Han Kim","doi":"10.5124/JKMA.2014.57.1.34","DOIUrl":"https://doi.org/10.5124/JKMA.2014.57.1.34","url":null,"abstract":"일반적으로 결핵 병변이 발생한 장소에 따라 폐결핵과 폐 외 결핵으로 구분한다. 예를 들어 객담 도말 양성이면서 폐 외 결핵이 동반된 경우는 폐결핵으로 분류한다. 그러나, 종 격동 림파선염, 결핵성 심낭염, 폐실질에 이상소견을 동반 하지 않는 결핵성 흉막염은 폐외 결핵으로 분류한다. 미국 의 결핵감시체계에 보고된 결핵 환자를 보면 폐외 결핵이 차지하는 비율이 1991년에는 16%에서 2001-2003년 사이 에 약 20%로 일정하게 유지되고 있다[1]. 이러한 폐외 결 핵의 빈도는 지역에 따라 다르게 보고되어 적게는 5%에서 많게는 35% 이상으로 보고되고 있다[1]. 미국에서 결핵 환 자의 역학적 특성을 분석한 데이터에 따르면, 아시아계 인 종이 다른 인종에 비해서 폐외 결핵의 빈도가 더 높은 것 으로 보고하였다[2]. 또한, 사람면역결핍바이러스(human immunodeficiency virus, HIV) 감염과 면역억제제 사용에 따른 면역저하 환자가 증가하고 있으므로 폐외 결핵의 중요 성은 점차 증가할 것으로 예상한다. 2011년에 우리나라의 결핵감시체계를 통하여 보고된 결핵 환자에서는 폐외 결핵 Diagnosing extrapulmonary tuberculosis (E-TB) remains a challenge because clinical samples obtained from sites that are not easily accessible are sometimes paucibacillary, decreasing the sensitivity of diagnostic tests. Adenosine deaminase (ADA) is widely used for adjunct diagnosis of E-TB with extrasanguinous fluid. However, ADA is not a specific marker for E-TB, so a more specific test is urgently needed for the confirmation of E-TB. Recently, an IFN-gamma releasing assay using peripheral blood mononuclear cells and extrasanguinous fluid mononuclear cells, and the newly-developed Xpert MTB/RFP have shown promising results for the rapid diagnosis of E-TB. Although the regimen of antituberculous medication for E-TB is similar to that for pulmonary tuberculosis, the treatment of E-TB is occasionally complicated due to a paradoxical response during antituberculous therapy and after the completion of antituberculous therapy, especially in tuberculous lymphadenopathy. The proposed algorithm for the management of paradoxical response in tuberculous lymphadenopathy is presented, and the treatment for E-TB in various sites is briefly reviewed.","PeriodicalId":20490,"journal":{"name":"Problemy tuberkuleza","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2002-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86243567","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}