Procedia Chemistry最新文献

Evaluation of UV-crosslinked Poly(ethylene glycol) Diacrylate/Poly(dimethylsiloxane) Dimethacrylate Hydrogel: Properties for Tissue Engineering Application 紫外交联聚(乙二醇)二丙烯酸酯/聚(二甲基硅氧烷)二甲基丙烯酸酯水凝胶的评价:组织工程应用性能

Procedia Chemistry Pub Date : 2016-01-01 Epub Date: 2016-03-24 DOI: 10.1016/j.proche.2016.03.032

Z.A. Abdul Hamid, K.W. Lim

{"title":"Evaluation of UV-crosslinked Poly(ethylene glycol) Diacrylate/Poly(dimethylsiloxane) Dimethacrylate Hydrogel: Properties for Tissue Engineering Application","authors":"Z.A. Abdul Hamid, K.W. Lim","doi":"10.1016/j.proche.2016.03.032","DOIUrl":"10.1016/j.proche.2016.03.032","url":null,"abstract":"<div><p>Hydrogels are widely used as biomaterials in biomedicalfields such as in drug delivery systems, cell-based therapies, wound dressing, implant materials for soft tissue and anti-adhesion materials due to its unique characteristics. The aim of this project is to fabricate UV-crosslinked hydrogel film with the tailored chemical and physical properties that can be utilized as scaffold. Three series of UV-crosslinked poly(ethylene glycol) diacrylate/ poly(dimethylsiloxane) dimethacrylate (PEGDA/PDMS-MA) hydrogels were fabricatedby exposing the precursor solutions under UV chamber that provides a spectral range of UVA at average intensity of 40<em>W/cm</em><sup>2</sup>. Equilibrium swelling ratio (ESR) was found higher in the UV-crosslinked hydrogels that exposed to the UV at shorter time, with lower loading of PDMS-MA, and higher molecular weight of PEGDA. The concentration of photoinitiator was found to haveinsignificant effect on ESR%. Whereas, dynamic contact angle (DCA) measurement revealed that the hydrophilicity was higher forPEGDA UV-crosslinked hydrogels with higher ratio. Besides, dynamic mechanical analysis (DMA)showed that the incorporation of PDMS-MA reduced the average value of compressive modulus of the UV-crosslinked hydrogels. Differential scanning calorimetry (DSC) analysis showed that lower glass transition temperature (<em>T</em><sub><em>g</em></sub>) of PDMS-MA could be related to the reduction of stiffness in UV-crosslinked hydrogels. It was found that the fabricated UV-crosslinked hydrogels were suited to cartilage tissue engineering application due to similar properties to the cartilage tissue.</p></div>","PeriodicalId":20431,"journal":{"name":"Procedia Chemistry","volume":"19 ","pages":"Pages 410-418"},"PeriodicalIF":0.0,"publicationDate":"2016-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.proche.2016.03.032","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79393157","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 23

Immobilization of Bromocresol Purple in Inorganic-Organic Sol-Gel Thin Film with Presence of Anionic and Non-ionic Surfactants 阴离子和非离子表面活性剂在无机-有机溶胶-凝胶薄膜上的固定化溴甲酚紫

Procedia Chemistry Pub Date : 2016-01-01 Epub Date: 2016-03-24 DOI: 10.1016/j.proche.2016.03.007

Mohd Nasha’ain Nordin, Nuruzatulifah Asari, Ahmad Aswad Mahaidin, Khairuldin MohdI Sha, Nik Mohd Azmi Nik Abdul Aziz

{"title":"Immobilization of Bromocresol Purple in Inorganic-Organic Sol-Gel Thin Film with Presence of Anionic and Non-ionic Surfactants","authors":"Mohd Nasha’ain Nordin, Nuruzatulifah Asari, Ahmad Aswad Mahaidin, Khairuldin MohdI Sha, Nik Mohd Azmi Nik Abdul Aziz","doi":"10.1016/j.proche.2016.03.007","DOIUrl":"10.1016/j.proche.2016.03.007","url":null,"abstract":"<div><p>Sol-gel materials known as organically modified silicates (ORMOSILs) offer interesting features such as chemical and mechanical stability. In this paper VTES (vinyltriethoxysilane) and TEOS (tetraalkoxysilane) are mixed in 3:1 ratio. Sol-gel solution was prepared by hydrolysis process of precursors by using ethanol as solvent. After a while a pH-sensitive indicator bromocresol purple (BCP) and surfactant were incorporate into the sol-gel mixture. The percentage of sodium dodecyl sulfate (SDS) and polyethylene glycol (PEG) which act as surfactant were varied to observe the effect of improving host material's nanostructure as well as the interaction between BCP and sol-gel matrices. The absorption peak of the BCP dye changed significantly in the presence of surfactant compared to pure VTES: TEOS mixture (control) in the range of 400 to 450nm. The presence of BCP dye in the sol-gel mixture can be determined via FTIR spectrum with a =C–H stretch in aromatics observed at 3100-3000 cm<sup>-1</sup> which represented the aromatic of the BCP structure. The addition of BCP and surfactant had influenced the FTIR spectra of VTES: TEOS sol-gel materials. Addition of an anionic surfactant to the sol-gel mixtures was found to increase the BCP dye and the sol-gel matrices interaction, thus reducing the dye's tendency to leach. This work shows that sol-gel derived matrices yield dyes with sufficient rigid environment and addition of the surfactant helps to improve the interaction of filler matrices. The anionic SDS shows better leaching resistant compared to non-ionic PEG surfactant. Results of this study offer an attractive possibility to optimize the doped sol gel matrices to be used as sensing material in aqueous condition.</p></div>","PeriodicalId":20431,"journal":{"name":"Procedia Chemistry","volume":"19 ","pages":"Pages 275-282"},"PeriodicalIF":0.0,"publicationDate":"2016-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.proche.2016.03.007","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89509195","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 8

A Statistical Prediction of Multiple Responses Using Overlaid Contour Plot on Hydroxyapatite Coated Magnesium via Cold Spray Deposition 羟基磷灰石包覆镁冷喷涂复合响应的覆盖等高线图统计预测

Procedia Chemistry Pub Date : 2016-01-01 Epub Date: 2016-03-24 DOI: 10.1016/j.proche.2016.03.091

Md Razi Hasniyati, Hussain Zuhailawati, Sivakumar Ramakrishnan

{"title":"A Statistical Prediction of Multiple Responses Using Overlaid Contour Plot on Hydroxyapatite Coated Magnesium via Cold Spray Deposition","authors":"Md Razi Hasniyati, Hussain Zuhailawati, Sivakumar Ramakrishnan","doi":"10.1016/j.proche.2016.03.091","DOIUrl":"10.1016/j.proche.2016.03.091","url":null,"abstract":"<div><p>This work aimed to search optimal values for the properties of hydroxyapatite coated pure magnesium produced by cold spray deposition. Using fractional factorial design (2<sup>k-1</sup>), standoff distance, surface roughness and substrate heating temperature during cold spraying were selected as significant factors while number of sprays as insignificant factor. The responses chosen are coating thickness, hardness and elastic modulus of the coating. The analysis of the contour plots for thickness revealed that high thickness (>40μm) was obtained when standoff distance is at 20-25mm, surface roughness at 240-700 grit and substrate heating temperature at 350-550°C. High nanohardness (>400MPa) obtained when standoff distance is at 20-35mm, surface roughness at 240-900grit and substrate heating temperature at 350-550°C. High elastic modulus (>40GPa) was obtained at 20-30mm for standoff distance, 240-800 grit for surface roughness and 350-550°C for substrate heating temperature. The contour plot of coating thickness, nanohardness and elastic modulus were overlaid to find the feasible region.</p></div>","PeriodicalId":20431,"journal":{"name":"Procedia Chemistry","volume":"19 ","pages":"Pages 181-188"},"PeriodicalIF":0.0,"publicationDate":"2016-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.proche.2016.03.091","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75389392","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 9

The Effect of Acrylic Acid on Tensile and Morphology Properties of Wollastonite Filled High Density Polyethylene/Natural Rubber Composites 丙烯酸对硅灰石填充高密度聚乙烯/天然橡胶复合材料拉伸性能和形貌的影响

Procedia Chemistry Pub Date : 2016-01-01 Epub Date: 2016-03-24 DOI: 10.1016/j.proche.2016.03.030

I. Yuhaida , H. Salmah , I. Hanafi , Z. Firuz

{"title":"The Effect of Acrylic Acid on Tensile and Morphology Properties of Wollastonite Filled High Density Polyethylene/Natural Rubber Composites","authors":"I. Yuhaida , H. Salmah , I. Hanafi , Z. Firuz","doi":"10.1016/j.proche.2016.03.030","DOIUrl":"10.1016/j.proche.2016.03.030","url":null,"abstract":"<div><p>Inorganic filler manufactured for incorporation into thermoplastic elastomers usually are surface treated with organic reagents in order to improve the interfacial adhesion between filler and the matrix. In the present paper, the effects of acrylic acid (AA) on tensile and morphology properties of wollastonite (WS) filled high density polyethylene (HDPE)/Natural Rubber (NR) composites were studied. The untreated and treated HDPE/NR/WS composites were melt-blending at 180°C with rotor speed of 50rpm for 10minutes. The composites were tensile-tested according to ASTM D638 and the etched surfaces were observed using scanning electron microscope (SEM). Tensile strength and elongation at break of the compositesdecreased upon the addition of wollastonite, but Young's modulus improves. The results of this study showed that the treated composites are found to have better tensile properties than the untreated composites. The morphology of treated composite showed better interfacial interaction between HDPE/NR and wollastonite.</p></div>","PeriodicalId":20431,"journal":{"name":"Procedia Chemistry","volume":"19 ","pages":"Pages 401-405"},"PeriodicalIF":0.0,"publicationDate":"2016-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.proche.2016.03.030","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89875167","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 4

Effect of Geological Condition on Degree of Fragmentation in a Simpang Pulai Marble Quarry 地质条件对新邦蒲莱大理石采石场破碎度的影响

Procedia Chemistry Pub Date : 2016-01-01 DOI: 10.1016/J.PROCHE.2016.03.072

K. N. Lyana, Z. Hareyani, A. Shah, M. Hazizan