Preparative Biochemistry & Biotechnology最新文献_第2页

Review: characterization polyhydroxybutyrate (PHB) production from Bacillus megaterium sp. microorganism for renewable plastics industry. 综述：再生塑料工业用巨芽孢杆菌生产聚羟基丁酸酯（PHB）的特性。

IF 1.9 4区生物学

Preparative Biochemistry & Biotechnology Pub Date : 2025-10-01 DOI: 10.1080/10826068.2025.2556869

Kharis Yohan Abidin, Abdullah, Yeyen Nurhamiyah, Muhson Isroni, Rossy Choerun Nissa, Radityo Pangestu, Dadang Suhendar, Akbar Hanif Dawam Abdullah

{"title":"Review: characterization polyhydroxybutyrate (PHB) production from Bacillus megaterium sp. microorganism for renewable plastics industry.","authors":"Kharis Yohan Abidin, Abdullah, Yeyen Nurhamiyah, Muhson Isroni, Rossy Choerun Nissa, Radityo Pangestu, Dadang Suhendar, Akbar Hanif Dawam Abdullah","doi":"10.1080/10826068.2025.2556869","DOIUrl":"https://doi.org/10.1080/10826068.2025.2556869","url":null,"abstract":"Polyhydroxybutyrate (PHB), a biodegradable biopolymer derived from microbes has been growing in popularity in light of the shift toward ecologically viable materials. Bacillus megaterium can produce large amounts of PHB, use a wide range of substrates (including biomass and industrial waste) and can adapt to several environmental conditions for growth and production. Bacillus megaterium shows strong potential for PHB production, achieving up to 78.4% yield (w/w), molecular weights of 200-800 kDa, and productivity up to 1.73 g/L·h-1 in fed-batch systems. It can utilize low-cost substrates such as molasses, crude glycerol, and lignocellulosic hydrolysates. Compared to Cupriavidus necator, its feedstock flexibility allows production cost reductions of up to 30% per ton in some studies. This review assesses some of the most significant progress made in producing PHB using B. megaterium, including: physicochemical characterization; genetic modifications; substrate variability; and fermentation method. We highlight key fermentation strategies, genetic modifications, and substrate innovations that have improved PHB yield and economic viability. Limitations such as downstream recovery challenges and the need for optimized feedstock pretreatment are critically discussed. Overall, B. megaterium has significant potential for sustainable production of PHB from renewable resources, helping to continue the development of reasonably priced and environmentally friendly bioplastics.","PeriodicalId":20401,"journal":{"name":"Preparative Biochemistry & Biotechnology","volume":" ","pages":"1-27"},"PeriodicalIF":1.9,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145200786","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Enhanced production of bacterial cellulose by co-culturing Komagataeibacter xylinus and Lactobacillus plantarum. 木林komagataeibacterium xylinus与植物乳杆菌共培养提高细菌纤维素产量。

IF 1.9 4区生物学

Preparative Biochemistry & Biotechnology Pub Date : 2025-09-24 DOI: 10.1080/10826068.2025.2564374

Yanli Fan, Yumin Yang, Yifan Cui, Yan Huang, Ye Chen

引用次数: 0

A review on secondary metabolites from endophytic fungi as potential source of bioactive substances for cosmeceutical products. 内生真菌次生代谢物作为药妆产品生物活性物质潜在来源的研究进展。

IF 1.9 4区生物学

Preparative Biochemistry & Biotechnology Pub Date : 2025-09-23 DOI: 10.1080/10826068.2025.2562464

Silva Abraham, Helen Octa Lentaya, Muhson Isroni, Rizka Gitami Sativa, Dicky Adihayyu Monconegoro, Teguh Baruji, Winda Tasia, Agus Supriyono, Nuralih, Elpri Eka Permadi, Sjaikhurrizal El Muttaqien

{"title":"A review on secondary metabolites from endophytic fungi as potential source of bioactive substances for cosmeceutical products.","authors":"Silva Abraham, Helen Octa Lentaya, Muhson Isroni, Rizka Gitami Sativa, Dicky Adihayyu Monconegoro, Teguh Baruji, Winda Tasia, Agus Supriyono, Nuralih, Elpri Eka Permadi, Sjaikhurrizal El Muttaqien","doi":"10.1080/10826068.2025.2562464","DOIUrl":"https://doi.org/10.1080/10826068.2025.2562464","url":null,"abstract":"Over the last century, research on the exploration of endophytic fungi has received tremendous attention worldwide due to their potency as an important source of natural bioactive compounds, particularly for the biomedical sectors. The biodiversity of the isolated bioactive compounds has shown various bioactivities, such as antioxidant, anti-inflammatory, anti-wrinkle, anti-pigmentation, antimicrobial, and anti-cancer. Concurrently, the cosmeceutical sector has experienced substantial market growth in recent decades, especially for cosmeceutical products with naturally occurring bioactive compounds. This trend is attributed to the growing concern of consumers over the hazardous effects of synthetic active substances, expecting greater biocompatibility, safety, and environmental friendliness. The current review focuses on endophytic fungi-derived secondary metabolites exerting cosmeceutical-related bioactivities. Special emphasis is placed on secondary metabolites with antioxidant, anti-melanogenic, and anti-inflammatory activities and a discussion of the main bioactive compounds and their respective bioassays. The wide array of bioactive compounds produced by the same fungal genus obtained from different plants. This review found that several endophytic fungal active compounds have better activities than standard compounds, reflecting the potential compounds for bioactive substances. This review also elaborates the challenge of increasing the scale of bioactive production by endophytic fungi on an industrial scale, which requires optimization of various parameters.","PeriodicalId":20401,"journal":{"name":"Preparative Biochemistry & Biotechnology","volume":" ","pages":"1-16"},"PeriodicalIF":1.9,"publicationDate":"2025-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145131852","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Valorization of low-grade Gracilaria verrucosa biomass via optimized acid hydrolysis: a sustainable route to high-value sugars for bioproduct development. 通过优化酸水解实现低品位疣子藤生物质的增值：生物产品开发的高价值糖的可持续途径。

IF 1.9 4区生物学

Preparative Biochemistry & Biotechnology Pub Date : 2025-09-20 DOI: 10.1080/10826068.2025.2560541

Rossy Choerun Nissa, Maya Irmayanti, Yeyen Nurhamiyah, Fateha Fateha, Akbar Hanif Dawam Abdullah, Deddy Triyono Nugroho Adi, Hidawati Hidawati, Hidayat Hidayat, Safri Ishmayana, Dadan Sumiarsa

{"title":"Valorization of low-grade Gracilaria verrucosa biomass via optimized acid hydrolysis: a sustainable route to high-value sugars for bioproduct development.","authors":"Rossy Choerun Nissa, Maya Irmayanti, Yeyen Nurhamiyah, Fateha Fateha, Akbar Hanif Dawam Abdullah, Deddy Triyono Nugroho Adi, Hidawati Hidawati, Hidayat Hidayat, Safri Ishmayana, Dadan Sumiarsa","doi":"10.1080/10826068.2025.2560541","DOIUrl":"https://doi.org/10.1080/10826068.2025.2560541","url":null,"abstract":"Low-grade Gracilaria verrucosa biomass, typically discarded during seaweed processing, remains underutilized despite its rich polysaccharide content. This study explores the valorization of this waste stream through optimized acid hydrolysis, comparing conventional water bath heating and pressurized steam pretreatment. A low-concentration sulfuric acid (H2SO4) hydrolysis process was statistically optimized using response surface methodology (RSM), employing a central composite design (CCD), yielding a maximum reducing sugar concentration of 56.54 g/L under pressurized steam conditions-substantially higher than 37.51 g/L under water bath treatment. Structural changes in the biomass were characterized via scanning electron microscopy (SEM), Fourier-transform infrared spectroscopy (FTIR), thermogravimetric analysis (TGA), and density measurements, revealing enhanced polysaccharide breakdown under pressurized conditions. Importantly, the sugar-rich hydrolysate, dominated by glucose and xylose, demonstrates potential as a substrate for microbial fermentation, supporting downstream bioproduct development such as biodegradable plastics. These findings offer a sustainable pathway for converting seaweed processing waste into high-value biochemical feedstocks using a mild, cost-effective hydrolysis process.","PeriodicalId":20401,"journal":{"name":"Preparative Biochemistry & Biotechnology","volume":" ","pages":"1-14"},"PeriodicalIF":1.9,"publicationDate":"2025-09-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145102997","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Biopolymer curdlan production from rhizospheric bacteria Priestia aryabhattai BMS3 from Vigna radiata (mung bean). 绿豆根际细菌Priestia aryabhattai BMS3生产生物聚合物凝乳素。

IF 1.9 4区生物学

Preparative Biochemistry & Biotechnology Pub Date : 2025-09-20 DOI: 10.1080/10826068.2025.2562316

Aditi Balasubramani, Eeshaan Koundinya, Natasha Aquinas, Nidhi G, Ramananda M Bhat, Subbalaxmi Selvaraj

{"title":"Biopolymer curdlan production from rhizospheric bacteria Priestia aryabhattai BMS3 from Vigna radiata (mung bean).","authors":"Aditi Balasubramani, Eeshaan Koundinya, Natasha Aquinas, Nidhi G, Ramananda M Bhat, Subbalaxmi Selvaraj","doi":"10.1080/10826068.2025.2562316","DOIUrl":"https://doi.org/10.1080/10826068.2025.2562316","url":null,"abstract":"Curdlan, a microbial polysaccharide with unique gelling properties, has garnered significant attention with widespread importance in the food, pharmaceutical, and biomedical industries. This study presents the first report on Priestia aryabhattai as a curdlan-producing bacterium isolated from the rhizosphere of Vigna radiata (mung bean) plants. A variety of carbon and nitrogen sources were screened where sucrose and diammonium hydrogen phosphate respectively yielded the best results. Process optimization using Taguchi method resulted in a significant 3.57-fold increase in curdlan yield, from 0.14 to 0.5 g/L. The optimal fermentation medium consisted of inoculum percentage (10%), (NH4)2HPO4 concentration (0.8%), KH2PO4 concentration (0.3%), and sucrose concentration (10%) along with trace elements at a pH 7.0. Techniques such as nuclear magnetic resonance (NMR) spectroscopy, Fourier-transform infrared spectroscopy (FTIR), and scanning electron microscopy (SEM) were utilized to characterize the extracted curdlan to confirm its structural and morphological properties. Some defining features of curdlan like the β-1,3-linkage were visualized through FTIR as the absorption band at 890 cm-1 and sharp, irregular fragmented structures as observed through SEM analysis. These findings highlight P. aryabhattai BMS3 as a novel curdlan producer and demonstrate an optimized approach for improving curdlan production efficiency.","PeriodicalId":20401,"journal":{"name":"Preparative Biochemistry & Biotechnology","volume":" ","pages":"1-15"},"PeriodicalIF":1.9,"publicationDate":"2025-09-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145102970","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Harnessing effluent treatment plant bioproducts: Polyhydroxyalkanoates as a green packaging material. 利用污水处理厂的生物制品：聚羟基烷酸酯作为绿色包装材料。

IF 1.9 4区生物学

Preparative Biochemistry & Biotechnology Pub Date : 2025-09-18 DOI: 10.1080/10826068.2025.2562323

Rekha Kanzariya, Alok Gautam, Shina Gautam

引用次数: 0

Enzyme inhibitory and bioactive potential of ultrasound-assisted water extract from Sideritis montana subsp. montana: phytochemical profiling and implications for therapeutic applications. 蒙大拿州菱形菌超声辅助水提物的酶抑制及生物活性潜力。蒙大拿：植物化学分析及其治疗应用。

IF 1.9 4区生物学

Preparative Biochemistry & Biotechnology Pub Date : 2025-09-18 DOI: 10.1080/10826068.2025.2562318

Nilay Isitez, Sevim Feyza Erdogmus, Cengiz Sarikurkcu, Bulent Kirkan, Olcay Ceylan, Abdulmetin Hartavi

{"title":"Enzyme inhibitory and bioactive potential of ultrasound-assisted water extract from Sideritis montana subsp. montana: phytochemical profiling and implications for therapeutic applications.","authors":"Nilay Isitez, Sevim Feyza Erdogmus, Cengiz Sarikurkcu, Bulent Kirkan, Olcay Ceylan, Abdulmetin Hartavi","doi":"10.1080/10826068.2025.2562318","DOIUrl":"https://doi.org/10.1080/10826068.2025.2562318","url":null,"abstract":"Introduction: Plant-derived polyphenols are increasingly sought as multi-target options against oxidative stress, metabolic disorders and cancer.Methods: An ultrasound-assisted water extract of Sideritis montana subsp. montana was chemically profiled and tested for antioxidant, enzyme-inhibitory, and cytotoxic activities.Results: The extract contained 30.08 mg GAEs/g phenolics and 22.18 mg/RE/g flavonoids; LC-ESI-MS/MS identified chlorogenic acid as the dominant metabolite (4120 µg/g). Antioxidant tests gave EC50 values of 1.59 mg/mL (phosphomolybdenum), 2.03 mg/mL (CUPRAC) and 0.72 mg/mL (FRAP); radical-scavenging IC50 values were 4.63 mg/mL (DPPH) and 2.80 mg/mL (ABTS). Enzyme assays showed inhibition of tyrosinase (IC50 1.92 mg/mL), BChE (3.39 mg/mL) and AChE (4.36 mg/mL), with weaker effects on α-amylase and α-glucosidase. In A549 lung-carcinoma cells the extract lowered viability to about 50% between 250 and 500 µg/mL, and exposure at this midpoint raised TNF-α from 3.39 to 18.23 ng/mL (∼5.4-fold) and TGF-β from 12.71 to 58.18 pg/mL (∼4.6-fold).Conclusions: Overall, the hydroxycinnamate-rich matrix exhibits moderate redox, enzyme-modulating and cytostatic activities, suggesting potential in cosmetic depigmentation or adjunct neuroprotection. Future fraction-guided isolation, broader cell panels and in vivo studies are needed to pinpoint active constituents, clarify cytokine implications and assess translational value.","PeriodicalId":20401,"journal":{"name":"Preparative Biochemistry & Biotechnology","volume":" ","pages":"1-8"},"PeriodicalIF":1.9,"publicationDate":"2025-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145081551","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Antioxidant and immunomodulatory activities of Rehmannia glutinosa extracts obtained with complex enzymes and ultrasonic wave. 复合酶和超声波提取地黄提取物的抗氧化和免疫调节活性。

IF 1.9 4区生物学

Preparative Biochemistry & Biotechnology Pub Date : 2025-09-16 DOI: 10.1080/10826068.2025.2562317

Zichao Wang, Zhihan Shu, Yuxuan Zhang, Changxing Liu, Tao Liu, Hongtao Zhang, Yingjie Feng, Xueyi Qiao, Danye Zhu, Dandan Liu, Qi Wang, Qinggong Chen, Lemei An

{"title":"Antioxidant and immunomodulatory activities of Rehmannia glutinosa extracts obtained with complex enzymes and ultrasonic wave.","authors":"Zichao Wang, Zhihan Shu, Yuxuan Zhang, Changxing Liu, Tao Liu, Hongtao Zhang, Yingjie Feng, Xueyi Qiao, Danye Zhu, Dandan Liu, Qi Wang, Qinggong Chen, Lemei An","doi":"10.1080/10826068.2025.2562317","DOIUrl":"https://doi.org/10.1080/10826068.2025.2562317","url":null,"abstract":"The comprehensive exploration and utilization of plants with both medicinal and culinary applications are crucial for human disease prevention and health maintenance. In this study, extracts of Rehmannia glutinosa were prepared using a complex enzyme- and ultrasound-assisted method. Bioactivity assays revealed that the R. glutinosa extracts exhibited potent radical-scavenging capabilities against DPPH, ABTS, hydroxyl, and superoxide radicals, with scavenging rates of 88.46% ± 1.35%, 98.90% ± 1.68%, 64.79% ± 1.12%, and 72.96% ± 1.46%, respectively. Furthermore, the extracts significantly protected RAW 264.7 cells from H2O2-induced oxidative damage, mitigating its effects and repairing cellular integrity. This was achieved by enhancing the activities of endogenous antioxidant enzymes, including superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GSH-Px), while concurrently reducing malondialdehyde (MDA) levels. Additionally, the R. glutinosa extracts stimulated the secretion of immune factors (TNF-α, IL-1β, IL-6, and NO) in RAW 264.7 cells in a dose-dependent manner. Although the specific bioactive compounds within the extracts were not isolated or identified in this work, these findings collectively demonstrate the potential of R. glutinosa extracts as a valuable source of natural antioxidant and immunomodulatory ingredients.","PeriodicalId":20401,"journal":{"name":"Preparative Biochemistry & Biotechnology","volume":" ","pages":"1-9"},"PeriodicalIF":1.9,"publicationDate":"2025-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145075886","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Characterization of a novel Glutaminase-free L-asparaginase from Bifidobacterium thermophilum. 嗜热双歧杆菌新型无谷氨酰胺酶l -天冬酰胺酶的鉴定。

IF 1.9 4区生物学

Preparative Biochemistry & Biotechnology Pub Date : 2025-09-11 DOI: 10.1080/10826068.2025.2559284

Jiaping Ge, Xiaojun Huang, Zhengyu Zhang

{"title":"Characterization of a novel Glutaminase-free L-asparaginase from Bifidobacterium thermophilum.","authors":"Jiaping Ge, Xiaojun Huang, Zhengyu Zhang","doi":"10.1080/10826068.2025.2559284","DOIUrl":"https://doi.org/10.1080/10826068.2025.2559284","url":null,"abstract":"L-asparaginase (ASNase), as a pivotal amidohydrolase enzyme, has been used in removing acrylamide in food processing and treating acute lymphoblastic leukemia in clinic. In this study, a novel ASNase from Bifidobacterium thermophilum (BtASNase) was successfully cloned and heterologously expressed in Escherichia coli. BtASNase was identified to share maximum 40% structural similarity with other ASNases in PDB database. The purified BtASNase with monomeric size about 35 kDa had the highest specific activity (554.82 IU/mg) at 55 °C and pH 8.0. Further investigation indicated that BtASNase showed great stability at wide pH range (6.0-11.0), and retained more than 85% of its activity for 50 min at 37 °C. To be noted, BtASNase exhibited high L-asparaginase specificity and zero glutaminase activity. To our knowledge, this is a novel exploration of ASNase from Bifidobacterium thermophilum, and the explored BtASNase could be a potential candidate with desirable advantages for overcoming limitations such as glutaminase activity, narrow pH range stability, and low thermostability restrict in industry applications of ASNase.","PeriodicalId":20401,"journal":{"name":"Preparative Biochemistry & Biotechnology","volume":" ","pages":"1-7"},"PeriodicalIF":1.9,"publicationDate":"2025-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145034163","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Response surface methodology optimization extraction of polysaccharide from Lilium brownii F.E. Brown var. viridulum Baker/Longya Baihe and its biological activities. 响应面法优化龙牙百合多糖提取工艺及其生物活性。

IF 1.9 4区生物学

Preparative Biochemistry & Biotechnology Pub Date : 2025-09-11 DOI: 10.1080/10826068.2025.2556871

Menglu Li, Ruotong He, Ceyao Yang, Hao Chen, Chaoling Wu, Xiaomiao Zhang, Xin Fu, Chengbo Lu, Liu Yang, Shi Liu, Yi Zhang

{"title":"Response surface methodology optimization extraction of polysaccharide from Lilium brownii F.E. Brown var. viridulum Baker/Longya Baihe and its biological activities.","authors":"Menglu Li, Ruotong He, Ceyao Yang, Hao Chen, Chaoling Wu, Xiaomiao Zhang, Xin Fu, Chengbo Lu, Liu Yang, Shi Liu, Yi Zhang","doi":"10.1080/10826068.2025.2556871","DOIUrl":"10.1080/10826068.2025.2556871","url":null,"abstract":"Lilium brownii F.E.Brown var. viridulum Baker (Longya Baihe), a traditional medicinal and edible plant. In order to study the activity of its polysaccharide extracts, a three-factor three-level Box-Behnken response surface design was employed to optimize the extraction process. The optimal extraction conditions include: liquid-solid ratio of 32:1 mL/g, extraction temperature of 70 °C, and extraction time of 3.5 h. The purified Longya Baihe polysaccharide (LP), obtained via DEAE-52 cellulose chromatography, was structurally characterized by molecular weight distribution, monosaccharide composition and infrared spectrum. The results show that LP was a macromolecular polysaccharide composed of glucose and mannose (molar ratio of 1:1.56), with an average molecular mass (Mn) of 24.006 kDa. In vitro assays demonstrated its excellent antioxidant and anti-inflammatory activities. LP significantly inhibited lipopolysaccharide (LPS)-induced activation of the nuclear factor kappa-B (NF-κB) pathway in RAW264.7 cells, downregulated the overexpression of nitric oxide (NO), interleukin (IL)-6, inducible nitric oxide synthase (iNOS) and tumor necrosis factor (TNF)-α, and enhancing the levels of the anti-inflammatory factor interleukin (IL)-10. This study suggests LP holds promise as a natural antioxidant and anti-inflammatory agent for potential development and application.","PeriodicalId":20401,"journal":{"name":"Preparative Biochemistry & Biotechnology","volume":" ","pages":"1-15"},"PeriodicalIF":1.9,"publicationDate":"2025-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145034226","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0