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Poster Presentations - Proffered Abstracts最新文献

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Abstract P204: Targeting the p300/CBP epigenetic pathway to overcome hormone therapy resistance in advanced prostate cancer P204:靶向p300/CBP表观遗传途径克服晚期前列腺癌激素治疗耐药
Poster Presentations - Proffered Abstracts Pub Date : 2021-12-01 DOI: 10.1158/1535-7163.targ-21-p204
E. Chen, Nathan M. Hawkey, Beatrice C. Thomas, Kathryn E. Ware, Daniella Runyambo, M. Caligiuri, E. Wilker, E. Soderblom, M. Moseley, S. Guichard, A. Armstrong, J. Somarelli
{"title":"Abstract P204: Targeting the p300/CBP epigenetic pathway to overcome hormone therapy resistance in advanced prostate cancer","authors":"E. Chen, Nathan M. Hawkey, Beatrice C. Thomas, Kathryn E. Ware, Daniella Runyambo, M. Caligiuri, E. Wilker, E. Soderblom, M. Moseley, S. Guichard, A. Armstrong, J. Somarelli","doi":"10.1158/1535-7163.targ-21-p204","DOIUrl":"https://doi.org/10.1158/1535-7163.targ-21-p204","url":null,"abstract":"","PeriodicalId":20348,"journal":{"name":"Poster Presentations - Proffered Abstracts","volume":"59 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72552620","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Abstract P258: CBX-12 (alphalexTM-exatecan) sensitizes tumors to immune checkpoint blockade in an antigen agnostic manner by immune activation 摘要:CBX-12 (alphalexTM-exatecan)通过免疫激活以抗原不可知的方式使肿瘤对免疫检查点阻断增敏
Poster Presentations - Proffered Abstracts Pub Date : 2021-12-01 DOI: 10.1158/1535-7163.targ-21-p258
S. Gayle, Juan C. Vasquez, T. Paradis, Kelli Jones, R. Sundaram, Jinny Van Doorn, Viswanathan Muthusamy, R. Bindra, R. Aiello, V. Paralkar
{"title":"Abstract P258: CBX-12 (alphalexTM-exatecan) sensitizes tumors to immune checkpoint blockade in an antigen agnostic manner by immune activation","authors":"S. Gayle, Juan C. Vasquez, T. Paradis, Kelli Jones, R. Sundaram, Jinny Van Doorn, Viswanathan Muthusamy, R. Bindra, R. Aiello, V. Paralkar","doi":"10.1158/1535-7163.targ-21-p258","DOIUrl":"https://doi.org/10.1158/1535-7163.targ-21-p258","url":null,"abstract":"","PeriodicalId":20348,"journal":{"name":"Poster Presentations - Proffered Abstracts","volume":"5 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73899232","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Abstract P055: Targeting Krebs-cycle-deficient renal cell carcinoma with PARP inhibitor and low-dose alkylating chemotherapy P055: PARP抑制剂联合小剂量烷基化化疗治疗krebs周期缺陷型肾癌
Poster Presentations - Proffered Abstracts Pub Date : 2021-12-01 DOI: 10.1158/1535-7163.targ-21-p055
Daiki Ueno, Amrita Sule, Jiayu Liang, Jinny Van Doorn, R. Sundaram, R. Caliliw, Huihui Ye, Rong Huang, Jing Li, Karla S. Boyd, R. Bindra, Juan C. Vasquez, B. Shuch
{"title":"Abstract P055: Targeting Krebs-cycle-deficient renal cell carcinoma with PARP inhibitor and low-dose alkylating chemotherapy","authors":"Daiki Ueno, Amrita Sule, Jiayu Liang, Jinny Van Doorn, R. Sundaram, R. Caliliw, Huihui Ye, Rong Huang, Jing Li, Karla S. Boyd, R. Bindra, Juan C. Vasquez, B. Shuch","doi":"10.1158/1535-7163.targ-21-p055","DOIUrl":"https://doi.org/10.1158/1535-7163.targ-21-p055","url":null,"abstract":"","PeriodicalId":20348,"journal":{"name":"Poster Presentations - Proffered Abstracts","volume":"69 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73435106","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Abstract P182: VRK1 is a novel synthetic lethal target in VRK2-methylated glioblastoma P182: VRK1是vrk2甲基化胶质母细胞瘤中一种新的合成致死靶点
Poster Presentations - Proffered Abstracts Pub Date : 2021-12-01 DOI: 10.1158/1535-7163.targ-21-p182
J. Shields, Samuel R Meier, Justin L. Engel, Madhavi Bandi, Maria Dam Ferdinez, Wenhai Zhang, Shan-Chuan Zhao, Minjie Zhang, Ashley H Choi, Yi Yu, Xuewen Pan, Brian J McMillan, Brett Williams, R. T. Sjin, D. Whittington, E. Wilker, A. Huang, Fang Li, N. Emmanuel
{"title":"Abstract P182: VRK1 is a novel synthetic lethal target in VRK2-methylated glioblastoma","authors":"J. Shields, Samuel R Meier, Justin L. Engel, Madhavi Bandi, Maria Dam Ferdinez, Wenhai Zhang, Shan-Chuan Zhao, Minjie Zhang, Ashley H Choi, Yi Yu, Xuewen Pan, Brian J McMillan, Brett Williams, R. T. Sjin, D. Whittington, E. Wilker, A. Huang, Fang Li, N. Emmanuel","doi":"10.1158/1535-7163.targ-21-p182","DOIUrl":"https://doi.org/10.1158/1535-7163.targ-21-p182","url":null,"abstract":"","PeriodicalId":20348,"journal":{"name":"Poster Presentations - Proffered Abstracts","volume":"93 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82169073","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Abstract P101: Combined metronomic chemo-immunotherapy in head and neck cancers: An experience from the developing and resource poor country P101:节拍化疗-免疫联合治疗头颈癌:来自发展中国家和资源贫乏国家的经验
Poster Presentations - Proffered Abstracts Pub Date : 2021-12-01 DOI: 10.1158/1535-7163.targ-21-p101
I. Madabhavi, Md Rasel Sarkar, Pham Nguyen Quy, A. Patel
{"title":"Abstract P101: Combined metronomic chemo-immunotherapy in head and neck cancers: An experience from the developing and resource poor country","authors":"I. Madabhavi, Md Rasel Sarkar, Pham Nguyen Quy, A. Patel","doi":"10.1158/1535-7163.targ-21-p101","DOIUrl":"https://doi.org/10.1158/1535-7163.targ-21-p101","url":null,"abstract":"","PeriodicalId":20348,"journal":{"name":"Poster Presentations - Proffered Abstracts","volume":"52 2 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87699876","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Abstract P199: Tenfibgen nanoencapsulated RNAi feCK2 inhibits protein kinase CK2 and induces apoptosis in feline oral squamous cell carcinomas in vivo 摘要P199: tenfigen纳米包封RNAi feCK2在体内抑制猫口腔鳞状细胞癌蛋白激酶CK2并诱导细胞凋亡
Poster Presentations - Proffered Abstracts Pub Date : 2021-12-01 DOI: 10.1158/1535-7163.targ-21-p199
F. Ondrey, G. Unger, C. Cannon, J. Trembley, BT Kren, J. Modiano, K. Ahmed
{"title":"Abstract P199: Tenfibgen nanoencapsulated RNAi feCK2 inhibits protein kinase CK2 and induces apoptosis in feline oral squamous cell carcinomas in vivo","authors":"F. Ondrey, G. Unger, C. Cannon, J. Trembley, BT Kren, J. Modiano, K. Ahmed","doi":"10.1158/1535-7163.targ-21-p199","DOIUrl":"https://doi.org/10.1158/1535-7163.targ-21-p199","url":null,"abstract":"","PeriodicalId":20348,"journal":{"name":"Poster Presentations - Proffered Abstracts","volume":"31 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84214194","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Abstract P064: Novel engineering of therapeutic Fusobacterium nucleatum phage for colorectal cancer treatment 摘要P064:治疗性核梭杆菌噬菌体治疗结直肠癌的新工程
Poster Presentations - Proffered Abstracts Pub Date : 2021-12-01 DOI: 10.1158/1535-7163.targ-21-p064
L. Ninio-Many, Yael Zigelman, N. Buchshtab, Yifat Elharar, Gal Eylon, E. Gidron, D. Berko-Ashur, J. Nicenboim, L. Zelcbuch, Einav Safyon Gartman, S. Kredo-Russo, Noga Kowalsman, I. V. Slutskin, I. Weiner, I. Gahali-Sass, N. Zak, S. Puttagunta, M. Bassan
{"title":"Abstract P064: Novel engineering of therapeutic Fusobacterium nucleatum phage for colorectal cancer treatment","authors":"L. Ninio-Many, Yael Zigelman, N. Buchshtab, Yifat Elharar, Gal Eylon, E. Gidron, D. Berko-Ashur, J. Nicenboim, L. Zelcbuch, Einav Safyon Gartman, S. Kredo-Russo, Noga Kowalsman, I. V. Slutskin, I. Weiner, I. Gahali-Sass, N. Zak, S. Puttagunta, M. Bassan","doi":"10.1158/1535-7163.targ-21-p064","DOIUrl":"https://doi.org/10.1158/1535-7163.targ-21-p064","url":null,"abstract":"","PeriodicalId":20348,"journal":{"name":"Poster Presentations - Proffered Abstracts","volume":"147 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86100887","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Abstract P231: Multigenomic characterization of context-dependent alternative splicing in normal and neoplastic cells P231:正常和肿瘤细胞中上下文依赖的选择性剪接的多基因组特征
Poster Presentations - Proffered Abstracts Pub Date : 2021-12-01 DOI: 10.1158/1535-7163.targ-21-p231
E. McMillan, K. Sriram, Emily Creger, Carsten Merkwirth, Raffaella Pippa, M. Pedraza, L. Do, Vishal S. Deshmukh, C. Bossard, M. White
{"title":"Abstract P231: Multigenomic characterization of context-dependent alternative splicing in normal and neoplastic cells","authors":"E. McMillan, K. Sriram, Emily Creger, Carsten Merkwirth, Raffaella Pippa, M. Pedraza, L. Do, Vishal S. Deshmukh, C. Bossard, M. White","doi":"10.1158/1535-7163.targ-21-p231","DOIUrl":"https://doi.org/10.1158/1535-7163.targ-21-p231","url":null,"abstract":"","PeriodicalId":20348,"journal":{"name":"Poster Presentations - Proffered Abstracts","volume":"18 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88514301","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Abstract P132: Promotion of E-cadherin-mediated tumor cell adhesion by COX-2/GSK3b signaling is a targetable mechanism of metastatic breast cancer P132: COX-2/GSK3b信号通路促进e -cadherin介导的肿瘤细胞粘附是转移性乳腺癌的一个可靶向机制
Poster Presentations - Proffered Abstracts Pub Date : 2021-12-01 DOI: 10.1158/1535-7163.targ-21-p132
Balamurugan Kuppusamy, S. Sehareen, S. Krishnamurthy, S. SharanA., W. Tang, N. Ueno, S. Ambs, Dipak K. Poria, Esta Sternecka
{"title":"Abstract P132: Promotion of E-cadherin-mediated tumor cell adhesion by COX-2/GSK3b signaling is a targetable mechanism of metastatic breast cancer","authors":"Balamurugan Kuppusamy, S. Sehareen, S. Krishnamurthy, S. SharanA., W. Tang, N. Ueno, S. Ambs, Dipak K. Poria, Esta Sternecka","doi":"10.1158/1535-7163.targ-21-p132","DOIUrl":"https://doi.org/10.1158/1535-7163.targ-21-p132","url":null,"abstract":"","PeriodicalId":20348,"journal":{"name":"Poster Presentations - Proffered Abstracts","volume":"26 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81154222","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Abstract P068: Different treatment schemes cause distinct PARP inhibitor resistance mechanisms in BRCA2-mutant ovarian cancer cells 摘要P068:不同的治疗方案在brca2突变卵巢癌细胞中引起不同的PARP抑制剂耐药机制
Poster Presentations - Proffered Abstracts Pub Date : 2021-12-01 DOI: 10.1158/1535-7163.targ-21-p068
Tzu-Ting Huang, J. Nair, N. Gupta, Tomomi M Yamamoto, Benjamin G. Bitler, Jung-Min Lee
{"title":"Abstract P068: Different treatment schemes cause distinct PARP inhibitor resistance mechanisms in BRCA2-mutant ovarian cancer cells","authors":"Tzu-Ting Huang, J. Nair, N. Gupta, Tomomi M Yamamoto, Benjamin G. Bitler, Jung-Min Lee","doi":"10.1158/1535-7163.targ-21-p068","DOIUrl":"https://doi.org/10.1158/1535-7163.targ-21-p068","url":null,"abstract":"","PeriodicalId":20348,"journal":{"name":"Poster Presentations - Proffered Abstracts","volume":"28 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81406755","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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