Legal regulation in veterinary medicine最新文献

{"title":"Study of Tildox AVZ effect on rat blood parameters in a subchronic experiment","authors":"O. A. Tokareva","doi":"10.52419/issn2782-6252.2024.1.76","DOIUrl":"https://doi.org/10.52419/issn2782-6252.2024.1.76","url":null,"abstract":"The purpose of our research was to study the effect of Tildox AVZ on rat blood counts in a subchronic experiment. Tildox is a complex antibiotic in powder form. One gram of drug contains doxycycline hyclate – 100 mg and tylosin tartrate - 100 mg as active ingredients, sodium benzoate and sucrose as auxiliary substances. The experiment lasted 90 days. The study was conducted on 150 Wistar rats (75 males and 75 females). The body weight of the animals was 190-230 g. During the experiment 5 groups of 30 animals (15 males and 15 females) were formed, three of them were experimental groups, one - control and one – intact. Of the 150 rats involved in the experiment after its completion 100 individuals (50 males and 50 females) were killed for pathomorphological studies of internal organs.To identify the ability to recover and the appearance of resistance to toxic effects the remaining 50 animals (5 males and 5 females from each group) were monitored for 28 days after the experiment.An aqueous solution of the test sample of the drug was administered daily intragastrically using an atraumatic metal probe. The drug was administered to the first experimental group at a dose of 70 mg / kg, the second group - 265 mg / kg, the third group - at a dose of 1000 mg / kg of animal body weight. The control group was in equal conditions and received intragastric saline solution. Intact animals served as a reference. It was found that Tildox AVZ administered intragastrically at doses of 265 and 1000 mg / kg 1 time per day for 90 days has an effect on clinical and biochemical blood parameters. The drug administered at a dose of 70 mg / kg does not cause changes in blood parameters. However when examining the blood of rats 28 days after the recovery period there were no significant changes in clinical and biochemical parameters compared with the control and intact groups.From this it can be concluded that all blood changes had a dose-dependent effect and after stopping the use of the drug the body recovered which indicates the reversibility of the caused shifts in the blood picture.","PeriodicalId":200544,"journal":{"name":"Legal regulation in veterinary medicine","volume":"18 24","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140732780","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Zoohygienic assessment of feed, the basis for successful prevention of padevyj toxidrome","authors":"A. F. Kuznetsov, K. A. Rozhkov, V. V. Achilov, A. Pechenkina","doi":"10.52419/issn2782-6252.2024.1.84","DOIUrl":"https://doi.org/10.52419/issn2782-6252.2024.1.84","url":null,"abstract":"This article presents a review of the literature and the results of our own research on the use of glucose-fructose syrup as a substitute for substandard honey and crystalline sugar in the diet of honey bees. The results of research on the search for feed products similar in properties to the natural feeds of honeybees are described, the characteristics of honey of different origins used for forage purposes are given, an idea of its quality and effect on the body of honeybees is given. Based on the conducted research, the authors conclude that in order to maintain optimal health, honey bees need to introduce new industrial products into beekeeping technology, in particular glucose-fructose syrups similar in sugar composition to nectar honey, in order to replace honeydew and feed from crystalline dietary sugar in the diet. The obtained materials can be used as a reference material for continuing research on the nutritional hygiene of honey bees, as well as in scientific activities and in practical beekeeping","PeriodicalId":200544,"journal":{"name":"Legal regulation in veterinary medicine","volume":"14 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140732704","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Description of the linear features of the exterior of the first –calfs of different origin","authors":"R. V. Paderina, N. Vinogradova","doi":"10.52419/issn2782-6252.2024.1.87","DOIUrl":"https://doi.org/10.52419/issn2782-6252.2024.1.87","url":null,"abstract":"In our country, a linear assessment of the exterior of animals is becoming increasingly widespread, which allows us to objectively assess the influence of the producer bull on the change in the most important exterior features that ensure the se-verity of the dairy type while maintaining high productivity and intensity of use in the herd. This ensures the ranking of animals by body type and helps to accelerate the genetic progress of productivity. In this regard, the introduction of a linear assessment of the daughters of breeding bulls in the herd of a breeding plant is relevant. We conducted research aimed at studying and analyzing the signs of a linear description of the exterior of the first-calf cows of the daughters of Holstein bulls and identifying the most common exterior flaws in one of the breeding plants of the Kirov region. The analysis of the data showed that the evaluated first-calf cows of different origins are characterized by exterior features: average height, body of medium depth, strong physique, pronounced dairy type. The most common disadvantages of the exterior of the examined heifer cows are: interception of the shoulder blades (25.6%), asymmetry of the udder lobes (23.0%), weak headstock (15.4%).","PeriodicalId":200544,"journal":{"name":"Legal regulation in veterinary medicine","volume":"52 13","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140733548","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The effects of gastrointestinal diet therapy for chronic pathologies of the digestive system in cats","authors":"A. V. Goncharova, V. A. Kostylev, V. Bychkova","doi":"10.52419/issn2782-6252.2024.1.62","DOIUrl":"https://doi.org/10.52419/issn2782-6252.2024.1.62","url":null,"abstract":"Gastroeintestinal diseases are one of the most common groups of diseases among small domestic animals. The gastro-intestinal tract includes the oral cavity, pharynx, esophagus, stomach, pancreas, small intestine and large intestine. General signs of digestive system disorders in cats with diseases of the digestive tract are vomiting, regurgitation, capricious appetite, as well as various defecation disorders: diarrhea, coprostasis, various inclusions in feces (blood, mucus). Diseases of the gastrointestinal tract of a chronic nature often involve the manifestation of symptoms on an ongoing basis or are recur-rent in nature. Chronic gastritis, enteropathy, pancreatitis require specialized diets that normalize the functioning of the digestive tract and help improve digestive function. These therapeutic complete diets are presented in ready-made feeds in dry (pellets) and wet (pates, pouches) variations from many manufacturers of industrial feeds. Dietary therapy is required long-term or lifelong; during remission it is the basis in the treatment of chronic patients. The compositions of these diets take into account the physiological and specific needs of the animal, and are also developed on the basis of easily digestible ingredients and a reduced amount of fat, but completely replenishing the required amount of calories.","PeriodicalId":200544,"journal":{"name":"Legal regulation in veterinary medicine","volume":"28 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140735228","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Isolation of cultures of microorganisms from pathological material from cows","authors":"M. Ladanova","doi":"10.52419/issn2782-6252.2024.1.41","DOIUrl":"https://doi.org/10.52419/issn2782-6252.2024.1.41","url":null,"abstract":"Rapidly developing antibiotic resistance limits the capabilities of veterinary specialists and doctors in the fight against infectious diseases. Effective diagnosis and continuous improvement in the field of antimicrobial therapy is the main approach in the treatment and prevention of bacterial infections. According to available data, bacteria are able to develop resistance in 2-3 years, while it takes an average of 5 years to develop and test a new antimicrobial drug. In our study, bacteriological examination of samples of pathological material from cows from 10 livestock farms in different districts of the Leningrad region was carried out, followed by determination of the sensitivity of isolated crops to antibiotics. In this study, 84 samples from cows were selected and examined and 115 cultures of microorganisms were isolated. As a result of the bacteriological study of the pathological material from cows, 9 groups and types of pathogenic and opportunistic microorganisms were identified. The main proportion is detected on staphylococci – 35.7%, mainly Staphylococcus aureus, epidermal staphylococcus and citrus staphylococcus. Escherichia coli (23.5%) and Proteus vulgaris (20.9%) were among the microorganisms in terms of frequency of occurrence. Most of the isolated cultures had average sensitivity to gentamicin, enrofloxacin, ciprofloxacin, ceftriaxone, cefepim, cefotaxime, neomecin; resistant to doxycycline, amoxicillin, levofloxacin, colistin, doxycycline, streptomycin, tylosin, tetracycline.","PeriodicalId":200544,"journal":{"name":"Legal regulation in veterinary medicine","volume":"27 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140734445","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Methodological features of the implementation of pharmacoeconomic models in veterinary medicine","authors":"V. S. Ponamarev","doi":"10.52419/issn2782-6252.2024.1.66","DOIUrl":"https://doi.org/10.52419/issn2782-6252.2024.1.66","url":null,"abstract":"The relevance of introducing pharmacoeconomic studies into veterinary medicine is undeniable, since they allow us to assess the cost and effectiveness of various medications and manipulations associated with their use, which helps veterinary specialists choose the most optimal treatment methods and prevent inappropriate or unnecessarily expensive con-sumption of medical resources. Such an economic assessment makes it possible to reduce the costs of veterinary care and ensure the availability of high-quality medical care for all categories of animals.The main problem of using existing pharmacoeconomic methods in veterinary medicine is the actual absence or impossibility of relevant assessment of certain characteristics (for example, indicators of the “benefit” of treatment for compaion animals; the integral indicator QALY - “years of quality life saved,” etc.), which allows us to consider analysis and generalization of methodological features of the implementation of pharmacoeconomic models in veterinary medicine is an urgent task.To achieve this goal, the scientific literature was analyzed (including bibliographic peer-reviewed databases such as Scopus, WoS, Pubmed, elibrary) with a further selection of relevant and current sources (published over the last 10 years) with their subsequent stratification according to the principle of applicability of the described methodological approaches for veterinary medicine, which were generalized and systematized.As a result of the analysis, it was determined that in veterinary medicine it is permissible to use analytical, statistical and simulation mathematical models.Pharmacoeconomic studies play an important role in assessing the relationship between treatment costs and outcomes. This allows you to evaluate the effectiveness of using a particular drug, conduct a comparative analysis of various treatment methods and make informed decisions about choosing the most suitable drug. In this way, pharmacoeconomic studies help improve the quality of veterinary treatment and ensure maximum benefit to the owner.","PeriodicalId":200544,"journal":{"name":"Legal regulation in veterinary medicine","volume":"29 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140735438","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparative analysis of the effectiveness of probiotic enterococcus strains in gastroenteritis in piglets","authors":"A. L. Sepp, A. V. Yashin, A. Prusakov","doi":"10.52419/issn2782-6252.2024.1.58","DOIUrl":"https://doi.org/10.52419/issn2782-6252.2024.1.58","url":null,"abstract":"According to a number of authors, a sharp change in the type of feeding and the effects of stress factors in piglets after weaning lead to disorders not only of metabolism, but also of membrane digestion, which further contributes to a decrease in body resistance and the occurrence of various diseases of the digestive organs.In the course of our study, it was found that the use of probiotic strains Enterococcus faecium L-3 and Enterococcus faecium 1-35 for the treatment of gastroenteritis in piglets during weaning had a similar effect on restoring intestinal enzymatic activity. In piglets that were not treated with probiotics (control 1), enzymatic activity in the digestive tract was only partially normalized during the study. We also evaluated some parameters of the ongoing metabolic processes in the body of weaning piglets by studying the biochemical blood parameters of the experimental groups after prescribing the probiotic strain Enterococcus faecium L-3 (experiment 1) and Enterococcus faecium 1-35 (experiment 2) comparing them with those of the control group of animals.","PeriodicalId":200544,"journal":{"name":"Legal regulation in veterinary medicine","volume":"39 22","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140735171","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The practice of creating buffer zones in anti-epizootic measures for rabies using the example of the border zone with Finland","authors":"L. S. Fogel, K. N. Gruzdev, L. N. Krotov, Yu. Yu. Danko","doi":"10.52419/issn2782-6252.2024.1.38","DOIUrl":"https://doi.org/10.52419/issn2782-6252.2024.1.38","url":null,"abstract":"One of the important tasks of veterinary medicine in the Russian Federation is the implementation of measures to prevent and eliminate infectious animal diseases[2]. Animal rabies is a zoonotic transboundary disease. It is characterized by natural focality, and wild carnivores, in particular the fox, are considered a reservoir of the rabies pathogen. Since the end of the twentieth century, oral rabies vaccines have been used to prevent rabies in Western Europe and the United States [1,3].This article presents the results of research work in 2003-2009. to create a buffer zone against animal rabies on the border with Finland by oral vaccination of wild carnivores in the Leningrad region, the Republic of Karelia. Live vaccines were used in the work: \"FUCHSORAL\" (Germany) and domestic ones - \"SINRAB\" (FGBU \"ARRIAH, Vladimir) and its analogue - the vaccine \"ORALRABIVAK\" produced by OJSC \"PZB\" (Pokrov).In the Leningrad region and the Republic of Karelia in 2003, the FUCHSORAL vaccine (Germany) was used once, and in subsequent years, double annual vaccination was carried out with domestic vaccines. In Finland, people were constantly vaccinated with the oral rabies vaccine “FUCHSORAL” (Germany), from the “SAD B19” strain [4]We carried out annual 2-fold vaccination (in spring and autumn) of wild carnivores, in accordance with the instructions for use of vaccines, at air temperatures from +2 to +8 C in a zone 50-80 km wide from the border for 6 years. The number of blood serum samples containing a level of rabies virus-neutralizing antibodies sufficient to protect against rabies in the Republic of Karelia increased from 0% to 80%, and in the Leningrad region. from 0% to 70%.As a result of the implementation of planned work in the period 2003-2009. to prevent rabies among wild carnivores in the Leningrad region and the Republic of Karelia, epizootic freedom from rabies was achieved, satisfying the neighboring country.","PeriodicalId":200544,"journal":{"name":"Legal regulation in veterinary medicine","volume":"34 15","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140734260","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prospects for pharmacological screening of oral detoxification drugs with differentiation of targeted pathologies in animal husbandry","authors":"O. Popova, O. A. Ukrainskaya","doi":"10.52419/issn2782-6252.2024.1.69","DOIUrl":"https://doi.org/10.52419/issn2782-6252.2024.1.69","url":null,"abstract":"In the modern livestock sector, the domestic industry of the North-West region, cases of poisoning of animals on farms and large complexes are increasingly occurring. This is primarily due to the intensive use of various synthetic modulators, growth stimulants, fertilizers in the agronomic industry and the excessive use of antibiotics, hormones and other veterinary drugs in animal husbandry.Pharmacological screening of oral detoxification agents with differentiation of target pathologies is a promising direction in the development of domestic animal husbandry. A reasonable choice of sorbents in each individual case of poisoning allows you to quickly achieve a therapeutic effect, reduce the toxic load on the animal’s body, which further ensures sustainable productivity and high quality products. This work highlights the results of some studies on the functional activity of the most common enterosorbents in relation to toxins of various natures.Based on the results of the study, it was noted that with an increase in pH from 2.0 (rennet model) to 7.5 (analogue of the distal small intestine), a release of part of the indicator substance from the pores of the sorbent (desorption) is observed, which reduces its absolute sorption effect [5] . The lowest desorption value was shown by atoxyl (8.5%) and phytopos (9.0%). That is why these drugs are the most effective oral detoxification agents for toxins with a molecular weight close to methylene blue.The maximum adsorption effect for various poisonings in animals can be achieved by using sorbing agents that are highly selective for a particular toxin. Research on the choice of oral detoxification agents with differentiation of target pathologies significantly expands the database on existing sorbents, makes it possible to prevent and treat poisonings of various types more effectively, and provides opportunities for the combined use of various adsorbent substances.","PeriodicalId":200544,"journal":{"name":"Legal regulation in veterinary medicine","volume":"39 8","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140734219","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Requirements for hunting products features of legal regulation","authors":"I. Chekhovskikh, E. M. Ol","doi":"10.52419/issn2782-6252.2024.1.29","DOIUrl":"https://doi.org/10.52419/issn2782-6252.2024.1.29","url":null,"abstract":"The article discusses the specific requirements for hunting products, which are enshrined in veterinary legislation, including veterinary rules. The authors analyzed federal legislation regarding the establishment of requirements for hunting products and the need to conduct a veterinary and sanitary expertise of hunted animals. The article states that the use of hunting products is possible only after the necessary measures have been taken, which include inspection of the carcass by the hunter or the responsible person of the hunting enterprise, taking biomaterial for veterinary and sanitary expertise and obtaining a conclusion.","PeriodicalId":200544,"journal":{"name":"Legal regulation in veterinary medicine","volume":"35 17","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140734248","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}