Pharmaciana最新文献

{"title":"Effect of ethanol solvent concentrations in pepino melon fruit (Solanum muricatum Aiton) extraction on total flavonoid, phenolic, and beta-carotene content","authors":"Girly Risma Firsty, N. Sugihartini, S. Mulyaningsih","doi":"10.12928/pharmaciana.v13i2.25226","DOIUrl":"https://doi.org/10.12928/pharmaciana.v13i2.25226","url":null,"abstract":"","PeriodicalId":20051,"journal":{"name":"Pharmaciana","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-07-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46745153","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison effectiveness of use antihypertensive in preeclampsia patient in RSUD Panembahan Senopati Bantul","authors":"A. Sari, Wisi Unggul Pertiwi, Faridah Baroroh","doi":"10.12928/pharmaciana.v13i2.23603","DOIUrl":"https://doi.org/10.12928/pharmaciana.v13i2.23603","url":null,"abstract":"Preeclampsia is one of many unsolved obstetric problems. The purpose of this research is to compare effectiveness of antihypertensive in preeclampsia patient in RSUD Panembahan Senopati Bantul in the period January-July 2019 . This study needs to analyze about antihypertensive drugs in preeclampsia because Preeclampsia is the 3rd rank of disease in pregnancy that causes maternal death after hemorrhagic and cardiovascular diseases. The study was conducted at Panembahan Senopati Hospital Bantul because hypertension in inpatient was ranked first in 10 distributions of non-communicable diseases. The research was observational analytic using a cross sectional study with retrospective data collection of patient medical record. Samples were selected on inclusion and exclusion criteria in 46 cases. Data analysis using Mann-Whitney to determine differences in drug effectiveness and Fisher's to determine the relationship. The results are found that no relationship between maternal age, obstetrical age, pregnancy status, method of birth, and length of stay, but there was a relationship between the severity of preeclampsia with the achievement of blood pressure targets. The results of comparative analysis of the effectiveness nifedipine monotherapy with combination of nifedipine + methyldopa there was a significant difference (p = 0.006), and there was a significant relationship between nifedipine monotherapy and combination of nifedipine + methyldopa (p = 0.015) OR results = 7.200. The conclusion of this study is more effective to use the combination of nifedipine + methyldopa for patients with preeclampsia.","PeriodicalId":20051,"journal":{"name":"Pharmaciana","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-07-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49639242","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Chlorogenic acid in preventing and curing ultraviolet-induced damage in human skin fibroblast as an antiaging cell model","authors":"E. Girsang, I. Lister, C. Ginting, W. Widowati, Seila Arumwardana, Meganita Marthania, R. Rizal","doi":"10.12928/pharmaciana.v13i2.24459","DOIUrl":"https://doi.org/10.12928/pharmaciana.v13i2.24459","url":null,"abstract":"","PeriodicalId":20051,"journal":{"name":"Pharmaciana","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-07-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47237763","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The sulphated polysaccharide compounds from green algae (Ulva lactuca L) as a potential natural anti-inflammatory agent based on molecular docking study targeting cyclooxygenase-2 receptor","authors":"Dwi Utami, Rezza Wahyudi, W. Widyaningsih","doi":"10.12928/pharmaciana.v13i2.25848","DOIUrl":"https://doi.org/10.12928/pharmaciana.v13i2.25848","url":null,"abstract":"","PeriodicalId":20051,"journal":{"name":"Pharmaciana","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-07-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47343686","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Gingerol and shogaol on red ginger rhizome (Zingiber officinale var. Rubrum) using high-performance liquid chromatography","authors":"J. Sukweenadhi, Putu Diah Damitasari, K. Kartini, Pissa Christanti, Evanie Noor Putri","doi":"10.12928/pharmaciana.v13i2.25246","DOIUrl":"https://doi.org/10.12928/pharmaciana.v13i2.25246","url":null,"abstract":"","PeriodicalId":20051,"journal":{"name":"Pharmaciana","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-07-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42482931","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Development of transdermal patch preparations binahong leaf extract (Anredera cordifolia (Ten.) Steenis) and antihyperglycemia test in rats","authors":"G. Ramadhan, Iis Wahyuningsih, W. Widyaningsih","doi":"10.12928/pharmaciana.v13i1.24602","DOIUrl":"https://doi.org/10.12928/pharmaciana.v13i1.24602","url":null,"abstract":"Binahong ( Anredera cordifolia) leaves are plants that have great potential as antihyperglycemics, and have chemical content including triterpenoids, flavonoids, and saponins. However, the development of binahong leaves in pharmaceutical preparations is still very lacking. Objectives of this study are knowing the transdermal patch formulation of binahong leaf extract (BLE) produces good physical properties and the development of BLE transdermal patches with different extract concentrations may blood glucose lower (BGL) levels in glucose-induced mice. This study uses a single-layer patch because it has the advantage of being able to penetrate faster and is suitable for compounds that have solubility in polar solvents. The research began with the extraction of binahong leaves, then formulated a transdermal BLE patch using a formula that includes HPMC (polymer), glycerol (plasticizer), oleic acid (enhancer) and tween 80 (enhancer). Diabetic rats were divided into 4 groups of 6 rats, negative control group (glucose + placebo), positive control group (glucose + insulin), FI group (glucose+ transdermal patch BLE 30%), and FII group (glucose + transdermal patch BLE 47%). The BGL measurements are carried out on the 0th, 3rd, 5th, and 7th days. The physical characterization carried out includes organoleptic, weight uniformity, thickness, pH, folding resistance, and moisture content, obtained FI and FII results that meet the requirements set out by each test standard. The BGL from day 1 to day 7 decreased in each group, positive control (68.8±3.76), negative control (112.5±6.89), FI (81.0±4.04), and FII (72.33±5.12). Based on the statistical results of the T-test on the physical evaluation of BLE transdermal patch preparations of FI and FII there were significant differences in weight and thickness uniformity, but there were no significant differences in pH, folding power, and humidity tests. The administration of a 47% BLE in FII transdermal patch provides insignificant BGL reduction effect compared to the 30% BLE in FI transdermal patch.","PeriodicalId":20051,"journal":{"name":"Pharmaciana","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-07-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48600288","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Proper practice Of unused medicine disposal: opinions of patients at puskesmas 1 Umbulharjo Yogyakarta","authors":"A. Hidayati, Ela Fadilah Pramsa, W. Supadmi","doi":"10.12928/pharmaciana.v13i1.25679","DOIUrl":"https://doi.org/10.12928/pharmaciana.v13i1.25679","url":null,"abstract":"","PeriodicalId":20051,"journal":{"name":"Pharmaciana","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48478750","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Validity and reliability of “Short-questionnaire of tuberculosis patients’ knowledge about anti-tuberculosis and hepatotoxicity” (SQ-KSH-TB)","authors":"D. Perwitasari, Muh. Deni Kurniawan, Lalu Muhammad Irham, I. N. Faridah, Triantoro Safaria, W. Supadmi, D. Setiawan","doi":"10.12928/pharmaciana.v13i1.24773","DOIUrl":"https://doi.org/10.12928/pharmaciana.v13i1.24773","url":null,"abstract":"","PeriodicalId":20051,"journal":{"name":"Pharmaciana","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48260361","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Publication trend of TMPRSS2 as SARS-CoV-2 receptor during the COVID-19 pandemic","authors":"Lalu Muhammad Irham, D. Perwitasari, Yudha Rizky Nuari, Wirawan Adikusuma, H. Dania, R. Maliza, Made Ary Sarasmita, Rocky Cheung","doi":"10.12928/pharmaciana.v13i1.24052","DOIUrl":"https://doi.org/10.12928/pharmaciana.v13i1.24052","url":null,"abstract":"","PeriodicalId":20051,"journal":{"name":"Pharmaciana","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48711351","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Nanoemulgel Activity of Binahong Leaf Extract (Anredera cordifolia) againts Wound Healing of Hyperglycemic Rats","authors":"Magfirah Septiani Yusuf, Iis Wahyuningsih, S. Yuliani","doi":"10.12928/pharmaciana.v13i1.24600","DOIUrl":"https://doi.org/10.12928/pharmaciana.v13i1.24600","url":null,"abstract":"","PeriodicalId":20051,"journal":{"name":"Pharmaciana","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49004095","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}