Accounts of Chemical Research最新文献_第3页

Morphology of the internal auditory canal: Deriving parameters from computer tomography scans. An observational STROBE-MR study. 内耳道形态学：从计算机断层扫描中提取参数。STROBE-MR 观察性研究。

IF 16.4 1区化学

Accounts of Chemical Research Pub Date : 2025-06-01 Epub Date: 2022-08-13 DOI: 10.1177/01455613221116196

Nandipha Mntungwa, Rene Human-Baron, Tania Hanekom

{"title":"Morphology of the internal auditory canal: Deriving parameters from computer tomography scans. An observational STROBE-MR study.","authors":"Nandipha Mntungwa, Rene Human-Baron, Tania Hanekom","doi":"10.1177/01455613221116196","DOIUrl":"10.1177/01455613221116196","url":null,"abstract":"Person-specific three-dimensional computational modelling plays a vital role in modern-day research of cochlear implants to assist in understanding the neural interface of the cochlea and implanted electrode array. Further improvements are made to these models as more parameters are included. Landmark assessment provides information and is frequently used to register coordinates for model generation as it captures small variations.ObjectivesThe objective of this study is to identify and define landmarks to adequately describe the internal auditory canal for inclusion in three-dimensional computational models of the cochlea and its surrounding structures.ParticipantsComputer tomography scans of live human cochleae were collected in the retrospective period. Descriptive and comparative statistics were used to describe the data obtained from the scans.ResultsThe mean anterior-posterior (AP) diameter at the base of the basal turn, the diameter of the AP at the midpoint of the IAC, and the anterior and posterior length of the internal acoustic canal were measured. 57.14% of the internal acoustic canals observed presented with a cylindrical, 40.48% was funnel-shaped and 2.38 % were bud-shaped. A statistically significant differences were found between the diameters of male and female internal acoustic meatus.ConclusionsThis paper serves as a reference that provides a set of references for the description of the internal acoustic canal for inclusion in three-dimensional computational reconstruction of the cochlea and surrounding structures.","PeriodicalId":1,"journal":{"name":"Accounts of Chemical Research","volume":" ","pages":"355-361"},"PeriodicalIF":16.4,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40699937","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Polypharmacy is Associated with Diabetic Foot Ulcers in Type 2 Diabetes mellitus. 多药治疗与 2 型糖尿病足溃疡有关。

IF 16.4 1区化学

Accounts of Chemical Research Pub Date : 2025-06-01 Epub Date: 2022-03-23 DOI: 10.1177/15347346221090756

Eren Imre, Erdi Imre

{"title":"Polypharmacy is Associated with Diabetic Foot Ulcers in Type 2 Diabetes mellitus.","authors":"Eren Imre, Erdi Imre","doi":"10.1177/15347346221090756","DOIUrl":"10.1177/15347346221090756","url":null,"abstract":"Objectives: This observational study aimed to investigate the relationship between polypharmacy and the existence of diabetic foot ulcers in patients with type 2 diabetes. Methods: Patients with T2DM with and without diabetic foot ulcers who presented to the endocrinology outpatient clinic between August 2020 and November 2021 were involved in the study. Overall, five hundred and twelve patients with T2DM (293 patients with diabetic foot ulcer and 219 patients without diabetic foot ulcer) were included. The exclusion criteria were pregnancy, lactation, type 1 diabetes, patients under 18 years and over 65 years of age, and history of malignancy. The information of drugs administered, demographic and clinical data were obtained from the patient files. The Wagner score was used to evaluate the severity of ulcers. Results: The comparison of the two groups revealed that patients with diabetic foot ulcers had significantly higher rates of diabetic retinopathy (p = 0.017). The patients with diabetic foot ulcers who had polypharmacy had significantly higher rates of hypertension, ischaemic heart disease, diabetic retinopathy, and complaints of diabetic neuropathy (P < 0.001, P < 0,001, p = 0.021 and P = 0.004, respectively). In the binary logistic regression analyses, polypharmacy was independently associated with diabetic foot ulcers in all models. Conclusion: Polypharmacy should be seriously concerned in type 2 diabetes mellitus in patients with diabetic foot ulcers and polypharmacy was related to diabetic foot ulcers.","PeriodicalId":1,"journal":{"name":"Accounts of Chemical Research","volume":" ","pages":"320-328"},"PeriodicalIF":16.4,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40317235","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Adolescent Women's Perspectives on Barriers and Facilitators to High School Bathroom Use. 青少年女性对高中使用浴室的障碍和促进因素的看法。

IF 16.4 1区化学

Accounts of Chemical Research Pub Date : 2025-06-01 Epub Date: 2022-12-04 DOI: 10.1177/10598405221142031

Elissa S Allen, Lisa Kane Low

引用次数: 0

Infratemporal Fossa Abscesses: A Systematic Review of Cases. 颞下窝脓肿：病例系统回顾

IF 16.4 1区化学

Accounts of Chemical Research Pub Date : 2025-06-01 Epub Date: 2022-08-12 DOI: 10.1177/01455613221121040

Kurtis Young, Dennis M Tang, Arthur W Wu

{"title":"Infratemporal Fossa Abscesses: A Systematic Review of Cases.","authors":"Kurtis Young, Dennis M Tang, Arthur W Wu","doi":"10.1177/01455613221121040","DOIUrl":"10.1177/01455613221121040","url":null,"abstract":"ObjectivesWe have attempted to characterize the clinical presentations and management of infratemporal fossa abscesses with the goal of improving awareness and promoting earlier diagnosis and treatment for this rare condition.Methodsan extensive systematic search was performed through Pubmed/Medline, CINAHL (EBSCOhost), and Web of Science. Two authors screened out studies by abstracts, and a third resolved any conflicts. The remaining studies were assessed by full-text assessment, leaving 43 studies for data extraction.Resultssixty-seven patients were included from the final 43 studies. The patients were predominantly male (56.7%), and the average age of patients was 44.3 years (standard deviation (SD) 19.8 years). Risk factors most commonly odontogenic, whether the etiology was through tooth extraction (n = 30, 44.8%) or infection (n = 17, 25.4%). Symptoms on presentation included pain (n = 40, 83.3%), swelling (n = 39, 81.3%), and trismus (n = 36, 75.0%). Twenty-two (32.8%) patients were managed with intraoral incision and drainage (I&D), 18 (26.9%) with extraoral I&D. After treatment, 45 of the 48 (93.8%) patients from the case reports and series were deemed to have achieved complete resolution.ConclusionsInfratemporal fossa abscesses are rare, but they may be associated with serious neurologic and systemic complications. Although prompt diagnosis paramount in avoiding these sequelae, patients often experienced delays in diagnosis. Surgical drainage and extended antibiotic therapy is recommended.","PeriodicalId":1,"journal":{"name":"Accounts of Chemical Research","volume":" ","pages":"375-382"},"PeriodicalIF":16.4,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40694892","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Morbidity and Oncological Outcome After Curative Treatment in Sinonasal Squamous Cell Carcinoma. 鼻窦鳞状细胞癌治愈治疗后的发病率和肿瘤学结果

IF 16.4 1区化学

Accounts of Chemical Research Pub Date : 2025-06-01 Epub Date: 2022-08-06 DOI: 10.1177/01455613221117787

Ralph Hohenberger, Sven Beckmann, Christoph Kaecker, Olgun Elicin, Roland Giger, Marco Caversaccio, Lukas Anschuetz

{"title":"Morbidity and Oncological Outcome After Curative Treatment in Sinonasal Squamous Cell Carcinoma.","authors":"Ralph Hohenberger, Sven Beckmann, Christoph Kaecker, Olgun Elicin, Roland Giger, Marco Caversaccio, Lukas Anschuetz","doi":"10.1177/01455613221117787","DOIUrl":"10.1177/01455613221117787","url":null,"abstract":"ObjectivesSinonasal squamous cell carcinomas are rare and aggressive tumors. Curative therapy includes surgery and radiotherapy, with high risk for local morbidity and impaired quality of life. The objective of this study was to analyze a large cohort of patients with sinonasal squamous cell carcinoma on treatment morbidity and oncological outcome.MethodsPatients with sinonasal squamous cell carcinoma (n = 75) treated at a tertiary referral center between 2008 and 2019 were identified. In patients with curative treatment intent (n = 70), a chart review and analysis on patient and tumor characteristics, morbidity, and oncological outcome was performed.ResultsMean follow-up was 59 months. Primary curative therapy was surgery alone (n = 18), surgery with radiation (n = 25), and primary (chemo)radiation (n = 27). Forty-two (60%) patients suffered from treatment-related morbidity; most frequent symptoms were dry nasal mucosa (20%), nasal obstruction (14.3%), and vision impairment or loss (11.5%). Patients with early disease had less morbidity (51.4 vs 71.1%; P = 0.09), a lower recurrence rate (27% vs. 48.5%; P = 0.08), and better overall survival (92.5% vs. 71.1%; P = 0.01).ConclusionTreatment-related morbidity is common after curative treatment of sinonasal squamous cell carcinomas. Early disease is beneficial in terms of occurrence and severity as multimodal treatment and recurrence can more likely be avoided.","PeriodicalId":1,"journal":{"name":"Accounts of Chemical Research","volume":" ","pages":"NP356-NP362"},"PeriodicalIF":16.4,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40677740","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Surgeon Preference on Sending Routine Tonsillectomy Specimens for Pathological Evaluation. 外科医生对将常规扁桃体切除术标本送去进行病理评估的偏好。

IF 16.4 1区化学

Accounts of Chemical Research Pub Date : 2025-06-01 Epub Date: 2022-08-08 DOI: 10.1177/01455613221112761

Nicholas A Rossi, Cecilia G Freeman, Jason F Ohlstein, Shiva Daram, Robert A Darling, Brian J McKinnon, Harold S Pine

{"title":"Surgeon Preference on Sending Routine Tonsillectomy Specimens for Pathological Evaluation.","authors":"Nicholas A Rossi, Cecilia G Freeman, Jason F Ohlstein, Shiva Daram, Robert A Darling, Brian J McKinnon, Harold S Pine","doi":"10.1177/01455613221112761","DOIUrl":"10.1177/01455613221112761","url":null,"abstract":"IntroductionDespite the presence of a growing body of literature suggesting cost-ineffectiveness of routine pathologic analysis of tonsillectomy specimens, little is known about common institutional policies and practice patterns of pediatric otolaryngologists. The objectives of this study were to determine the prevalence of routine pathological evaluation of tonsillectomy specimens for uncomplicated pediatric adenotonsillectomy procedures and to evaluate opinions regarding this controversy among board-certified pediatric otolaryngologists.MethodsThis was a cross-sectional survey study sent to board-certified pediatric otolaryngologists currently practicing and registered with the American Society of Pediatric Otolaryngology (ASPO) assessing their institutions' or practices' current policies on sending routine tonsillectomy specimens for pathology, their experience with this practice, and their opinions on whether routine pathologic analysis should be employed. Basic statistical analysis was then conducted.ResultsRespondents mostly practiced in an academic setting (68.4%), with the next most common being academically affiliated private practice (21.8%), and private practice was the least common (9.8%). Most respondents (85.1%) did not agree with routine pathologic analysis of otherwise uncomplicated pediatric tonsillectomy specimens.ConclusionMost pediatric otolaryngologists who responded to this survey do not support routine pathological analysis of otherwise uncomplicated pediatric tonsillectomy specimens. However, the results are likely biased and should be interpreted carefully, since only a small percentage of pediatric otolaryngologists responded to the survey. Potential cost savings could be seen by patients, payers, and hospital systems with judicious use of surgical pathology, specifically in cases with concurrent signs or symptoms suspicious for malignancy.","PeriodicalId":1,"journal":{"name":"Accounts of Chemical Research","volume":" ","pages":"NP373-NP380"},"PeriodicalIF":16.4,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40594103","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The desire for parenthood among individuals with intellectual disabilities : systematic review. 智障人士对为人父母的渴望：系统综述。

IF 16.4 1区化学

Accounts of Chemical Research Pub Date : 2025-06-01 Epub Date: 2022-11-28 DOI: 10.1177/17446295221141946

Tamara Guénoun, Aziz Essadek, Christophe Clesse, Marion Mauran-Mignorat, Estelle Veyron-Lacroix, Albert Ciccone, Barbara Smaniotto

引用次数: 0

Submandibular Nodular Fasciitis. 下颌结节性筋膜炎

IF 16.4 1区化学

Accounts of Chemical Research Pub Date : 2025-06-01 Epub Date: 2022-08-27 DOI: 10.1177/01455613221118889

Morgan E Davis, Shiv H Patel, Oluwole Fadare, Andrew M Vahabzadeh-Hagh

引用次数: 0

A Rare Case of Tonsillar Lipoma. 扁桃体脂肪瘤的罕见病例

IF 16.4 1区化学

Accounts of Chemical Research Pub Date : 2025-06-01 Epub Date: 2022-08-22 DOI: 10.1177/01455613221118893

Elif Gozgec, Hayri Ogul

引用次数: 0

Vitamin B₁₂ and Diabetic Foot: Α Mini-Review. 维生素 B12 与糖尿病足：微型综述。

IF 16.4 1区化学

Accounts of Chemical Research Pub Date : 2025-06-01 Epub Date: 2022-11-29 DOI: 10.1177/15347346221143018

Nikolaos D Karakousis, Elisavet E Pyrgioti, Petros N Georgakopoulos, Nikolaos Papanas

引用次数: 0