Pediatric Dental Journal最新文献

{"title":"Histopathological evaluation of pulpal health in traumatized discoloured primary incisors: A cross-sectional study","authors":"Revathy Viswanathan ,&nbsp;Dhanraj Kalaivanan ,&nbsp;Sujatha Anandan","doi":"10.1016/j.pdj.2025.100361","DOIUrl":"10.1016/j.pdj.2025.100361","url":null,"abstract":"<div><h3>Objective(s)</h3><div>Tooth discoloration following trauma in primary dentition is a clinical indicator of potential pulpal pathology This study aims to assess the histological status of pulpal health in discolored traumatized primary incisors and its correlation with discoloration types.</div></div><div><h3>Materials and Methods</h3><div>A cross-sectional study was conducted on 55 pediatric outpatients (ages 3–7 years) between July 2021 and December 2022. Demographic details, time elapsed after trauma (TET), presence of symptoms, and discoloration type (Yellow, Grey, Pink, or Red) were documented. The extracted pulp tissue samples underwent histopathological assessment and were classified as: Normal/Healthy Pulp, Inflamed Pulp, Partial Necrosis, or Complete Necrosis. Statistical analyses were performed using the Chi-square test with a 95% significance threshold.</div></div><div><h3>Results</h3><div>Greyish discoloration was the most prevalent (87%), followed by pink (11%) and yellow (2%). Most cases (89%) were clinically asymptomatic, with 56.36% reported within six months of trauma. Histopathological examination revealed partial necrosis (42%), complete necrosis (38%), and inflammation (20%) in all discolored teeth. Despite these findings, no statistically significant correlation was established between discoloration type, histopathological pulp status, and TET (p&gt;0.05).</div></div><div><h3>Conclusion</h3><div>(s): Greyish discoloration frequently coincides with pulpal necrosis. However, given study limitations, endodontic treatment should be guided by clinical and radiographic assessments rather than discoloration alone.</div></div>","PeriodicalId":19977,"journal":{"name":"Pediatric Dental Journal","volume":"35 3","pages":"Article 100361"},"PeriodicalIF":0.8,"publicationDate":"2025-10-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145219404","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Regenerative endodontic treatment in avulsed immature permanent teeth: A scoping review","authors":"Nahawand Koum ,&nbsp;Mazen Musa ,&nbsp;Riham Awad ,&nbsp;Salma Izeldin ,&nbsp;Qingyu Guo ,&nbsp;Ning Dong","doi":"10.1016/j.pdj.2025.100363","DOIUrl":"10.1016/j.pdj.2025.100363","url":null,"abstract":"<div><h3>Aim</h3><div>This scoping review assessed the performance of regenerative endodontic treatment (RET) in avulsed immature permanent teeth, which presented a significant challenge in dental trauma management. This scoping review aims to evaluate RET outcomes, protocols, complications, and effectiveness in avulsed immature permanent teeth, identifying research gaps to advance clinical application.</div></div><div><h3>Materials and methods</h3><div>The review encompassed a comprehensive search of PubMed, Cochrane Central Register of Controlled Trials, Web of Science, Scopus, and Science Direct, spanning over 20 years, supplemented by snowball searching. Full-text articles in any language were eligible if they were randomized/non-randomized clinical trials or prospective/retrospective cohort studies with at least 12 months of follow-up, following the PCC framework. Data were extracted using standardized forms, including author(s), publication year, study origin, aim, sample size, intervention protocol, follow-up, outcome measures, and measurement methods.</div></div><div><h3>Results</h3><div>Of the 1623 records reviewed, 14 studies met the inclusion criteria. These studies, involving 82 avulsed immature anterior teeth, demonstrated an overall success rate of 44 % (36/82) over a minimum 12-month follow-up, with success defined by periapical radiolucency resolution and positive root development. The included studies showed significant variability in RET protocols, with calcium hydroxide as the primary intracanal medicament, blood clot as the main scaffold, and 17 % (Ethylenediaminetetraacetic acid) EDTA with saline as the most common irrigation method. Notably, extra-alveolar time and storage conditions significantly influenced outcomes, with replantation within 60 min using a physiological medium yielding the best results.</div></div><div><h3>Conclusion</h3><div>While RET demonstrates approximately 44 % success in treating avulsed immature teeth, the variability in treatment protocols and the limited sample sizes in current studies highlight the need for more extensive research and standardized protocols to validate its use by dental practitioners.</div></div>","PeriodicalId":19977,"journal":{"name":"Pediatric Dental Journal","volume":"35 3","pages":"Article 100363"},"PeriodicalIF":0.8,"publicationDate":"2025-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145219291","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Oral and maxillofacial manifestations of Noonan and Costello overlap syndrome: A case report and literature review","authors":"Melissa D. Porter ,&nbsp;Kristin Smith ,&nbsp;Rashawn Jackson ,&nbsp;Mirissa Price ,&nbsp;Zaid H. Khoury","doi":"10.1016/j.pdj.2025.100362","DOIUrl":"10.1016/j.pdj.2025.100362","url":null,"abstract":"<div><div>Noonan syndrome (NS) and Costello syndrome (CS) are autosomal dominant anomalies belonging to the RASopathies; a group of disorders characterized by germline mutations of the Ras-MAPK signaling pathway. Although each RASopathy is unique, overlapping phenotypic features have been reported due to the common signaling pathway involved in the pathogenesis of these syndromes. Collectively, RASopathies’ incidence is about 1: 1000 births. Hallmark overlapping features of these disorders include distinctive maxillofacial deformities, developmental delays, mental deficiencies, and congenital heart defects. Dentoalveolar manifestations consist of high arched palates, gum disease, severe dental caries, malocclusions, enamel defects, and micrognathia. This case report highlights the rarity of these syndromes, clinical features of a recent case, as well as oral health management and maintenance along with a literature review.</div></div>","PeriodicalId":19977,"journal":{"name":"Pediatric Dental Journal","volume":"35 3","pages":"Article 100362"},"PeriodicalIF":0.8,"publicationDate":"2025-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145117899","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Characterization of gene expression profile of dental pulp stem cells from human exfoliated deciduous teeth (SHED) in down syndrome","authors":"Itaru Komine ,&nbsp;Yuta Chiba ,&nbsp;Hiroshi Sato ,&nbsp;Sae Oka ,&nbsp;Keigo Yoshizaki ,&nbsp;Aya Yamada ,&nbsp;Satoshi Fukumoto","doi":"10.1016/j.pdj.2025.100360","DOIUrl":"10.1016/j.pdj.2025.100360","url":null,"abstract":"<div><h3>Objectives</h3><div>Down syndrome is caused by trisomy of chromosome 21 and shows various phenotype in organs. The patients often suffer dental anomalies such as hypodontia and enamel hypoplasia, however, the mechanism of dental anomalies associated to Down syndrome remains unclear. To clarify the details of the dental phenotype of Down syndrome, we performed RNA-sequence (RNA-seq) of dental pulp stem cells from human exfoliated deciduous tooth (SHED).</div></div><div><h3>Materials and methods</h3><div>Three children with Down syndrome were selected as the patient group, and three healthy children were selected as the control group. Dental pulp was collected from extracted teeth during the replacement period between the ages of 5 and 8, and SHED was cultured. RT-qPCR was used to confirm whether there was a difference in the expression level of the gene on chromosome 21. MTT assay and colony formation assay was performed to examine cell proliferation ability. RNA-seq was performed to comprehensively analyze the gene expression difference between control group and Down syndrome group.</div></div><div><h3>Results</h3><div>SHED of control group and Down syndrome group showed no significant difference in cell shape and proliferation activity, while, the expression of COL6A1 was around 1.5-fold change upregulated in Down syndrome group, suggesting that the gene of chromosome 21 became trisomy. RNA-seq analyses revealed that the genes related to organ morphogenesis were upregulated. Furthermore, several genes important for tooth development was raised as significantly upregulated genes.</div></div><div><h3>Conclusion</h3><div>Genetic analysis using SHED was considered a useful tool for elucidating the mechanisms of dental anomalies in Down syndrome.</div></div>","PeriodicalId":19977,"journal":{"name":"Pediatric Dental Journal","volume":"35 3","pages":"Article 100360"},"PeriodicalIF":0.8,"publicationDate":"2025-09-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145104381","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Causes and prevention of near-miss choking events in childcare facilities 1. child factors","authors":"Kai Shibahara ,&nbsp;Luna Osakabe ,&nbsp;Akiko Ishizaki ,&nbsp;Hyosong Kwon ,&nbsp;Naofumi Shimomura ,&nbsp;Tomomi Sugiyama ,&nbsp;Miyuki Hamano ,&nbsp;Shouji Hironaka ,&nbsp;Takahiro Funatsu","doi":"10.1016/j.pdj.2025.100357","DOIUrl":"10.1016/j.pdj.2025.100357","url":null,"abstract":"<div><h3>Introduction</h3><div>This study investigates the incidence of near-miss choking events in childcare facilities and their association with children's eating behaviors and developmental status to develop prevention strategies.</div></div><div><h3>Methods</h3><div>A web-based survey was conducted among childcare workers employed at municipal facilities, social welfare corporations, and the National Council of Childcare Centers. Of the 1661 respondents, 1648 consenting participants were included in the analysis. We collected data on their places of work, sociodemographic characteristics, causes and prevention of choking near-miss incidents, and physical conditions of the children involved.</div></div><div><h3>Results</h3><div>Eating behaviors most frequently associated with near-miss choking events were stuffing food into the mouth, large bite size, insufficient chewing during meals, swallowing food without chewing, and fast eating. Children with growth-related concerns, those with developmental delays, or those who caused anxiety for caregivers were significantly more likely to exhibit these risky eating behaviors.</div></div><div><h3>Conclusions</h3><div>Problematic eating behaviors are strongly linked to children's growth, development, and caregiver anxiety; therefore, careful observation and support are essential to prevent choking events.</div></div>","PeriodicalId":19977,"journal":{"name":"Pediatric Dental Journal","volume":"35 3","pages":"Article 100357"},"PeriodicalIF":0.8,"publicationDate":"2025-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145018839","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association between food difficulty and oral function in school-aged children","authors":"Haruka Koyama ,&nbsp;Kaori Ishii ,&nbsp;Yusuke Suzuki ,&nbsp;Syo Kuroe ,&nbsp;Toshio Wani ,&nbsp;Shinichi Negishi","doi":"10.1016/j.pdj.2025.100359","DOIUrl":"10.1016/j.pdj.2025.100359","url":null,"abstract":"<div><h3>Objective</h3><div>This study aimed to investigate the relationship between children's subjective perception of food difficulty and the physical properties of foods, and to examine how these factors are associated with oral function development.</div></div><div><h3>Methods</h3><div>A questionnaire survey on “food difficulty” was conducted on 25 types of foods with 133 first-grade elementary school students (70 boys and 63 girls). The physical properties of the foods (hardness, cohesiveness, and adhesiveness) were measured. The masticatory difficulty score for each child was calculated by integrating texture values with their subjective evaluations. In addition, oral function measurements were conducted, including occlusal force, lip-closing strength, tongue pressure, masticatory performance, and masticatory path width. Associations between masticatory difficulty scores and oral function were analyzed using Spearman's rank correlation.</div></div><div><h3>Results</h3><div>Foods with higher hardness and cohesiveness were rated as more difficult to eat. Children who perceived hard and cohesive foods as difficult to eat tended to exhibit a lower occlusal force and reduced masticatory performance, suggesting an underdeveloped masticatory function. However, the association with adhesiveness was limited, indicating the potential influence of non-physical factors such as preference or food shape.</div></div><div><h3>Conclusion</h3><div>Children's subjective perception of food difficulty is closely related to food texture, particularly hardness and cohesiveness, and is associated with oral function development. These findings suggest that incorporating food texture into oral health assessment and dietary education is a beneficial approach, as it may help foster eating habits that promote the development of masticatory function in children.</div></div>","PeriodicalId":19977,"journal":{"name":"Pediatric Dental Journal","volume":"35 3","pages":"Article 100359"},"PeriodicalIF":0.8,"publicationDate":"2025-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145018840","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Non-plaque-induced gingivitis and oral complications in a pediatric patient on long-term mechanical ventilation – A case report","authors":"Yuta Hirofuji,&nbsp;Itaru Komine,&nbsp;Saki Hirofuji,&nbsp;Fumiko Takayama,&nbsp;Mitsuki Chiba,&nbsp;Aya Yamada,&nbsp;Satoshi Fukumoto","doi":"10.1016/j.pdj.2025.100358","DOIUrl":"10.1016/j.pdj.2025.100358","url":null,"abstract":"<div><h3>Background</h3><div>Oral care is essential for preventing ventilator-associated pneumonia (VAP) in intensive care units (ICUs) patients. Patients in pediatric ICUs (PICUs) require specialized oral management due to anatomical and developmental factors, yet detailed reports are limited.</div></div><div><h3>Case presentation</h3><div>We report a 9-year-old girl with chronic heart failure who developed ventilator-associated gingivitis (VAG) and other oral complications during long-term mechanical ventilation. Oral management was conducted collaboratively by pediatric dentists, dental hygienists, nurses, and physicians.</div></div><div><h3>Conclusion</h3><div>This case underscores the importance of early, continuous oral care and interdisciplinary collaboration in managing oral complications and supporting overall health in ventilated PICUs patients.</div></div>","PeriodicalId":19977,"journal":{"name":"Pediatric Dental Journal","volume":"35 3","pages":"Article 100358"},"PeriodicalIF":0.8,"publicationDate":"2025-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144987969","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Review of hypodontia and its impact on oral health related quality of life in children","authors":"Angel Rauniyar ,&nbsp;Jad Clarke ,&nbsp;Constance Law ,&nbsp;Neeta Prabhu","doi":"10.1016/j.pdj.2025.100356","DOIUrl":"10.1016/j.pdj.2025.100356","url":null,"abstract":"<div><h3>Background</h3><div>Hypodontia can be defined as the developmental absence of one or more teeth, excluding third molars. It can affect both primary and permanent dentitions and lead to challenges in aesthetics, speech and masticatory function as well as emotional and social wellbeing.</div></div><div><h3>Objective</h3><div>This review will explore the background to hypodontia and assess its impact on the oral health related quality of life (OHRQoL) in children.</div></div><div><h3>Results</h3><div>There is limited literature that assesses the OHRQoL in younger age groups with hypodontia (&lt;11 years of age) and the effect of oral rehabilitation on OHRQoL in children. <em>Conclusions</em>: Further research on the impact of treatment on patient satisfaction and the OHRQoL in children during their mixed dentition phase is necessary to guide the development of management strategies tailored to the unique needs of children with hypodontia.</div></div>","PeriodicalId":19977,"journal":{"name":"Pediatric Dental Journal","volume":"35 3","pages":"Article 100356"},"PeriodicalIF":0.8,"publicationDate":"2025-08-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144864652","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Knowledge, perception, attitude, practice and awareness of dentists and dental students about molar-incisor hypomineralization: A systematic review","authors":"Lilibeth-Stephania Escoto-Vasquez ,&nbsp;Mario Alberto Alarcón-Sánchez ,&nbsp;Julieta Sarai Becerra-Ruiz ,&nbsp;Ruth Rodríguez-Montaño ,&nbsp;Sarah Monserrat Lomelí-Martínez ,&nbsp;Diana Elizabeth Aguirre-Cortés ,&nbsp;Artak Heboyan","doi":"10.1016/j.pdj.2025.100355","DOIUrl":"10.1016/j.pdj.2025.100355","url":null,"abstract":"<div><h3>Aim</h3><div>Molar-incisor hypomineralization (MIH) is a developmental enamel defect that presents diagnostic and treatment challenges for dental professionals. Understanding the knowledge, perception, attitude, practice, and awareness of MIH is essential for improving its management in pediatric dentistry. This systematic review evaluates the knowledge, perception, attitude, practice, and awareness of MIH among dentists and dental students.</div></div><div><h3>Methods</h3><div>A systematic search was conducted across PubMed, Scopus, ScienceDirect, Web of Science, EBSCO, and Google Scholar following PRISMA guidelines. Cross-sectional studies were included, and the methodological quality was assessed using the Joanna Briggs Institute (JBI) checklist.</div></div><div><h3>Results</h3><div>Out of 2499 identified articles, 38 met the inclusion criteria, comprising 11,129 participants. Data collection was primarily conducted via Email (44.73 %), Google Forms (31.57 %) and direct questionnaire (15.78 %). Most studies assessed knowledge (89.47 %), followed by perception (60.52 %), practice (47.36 %), attitude (34.21 %), and awareness (10.52 %). Pediatric dentists demonstrated higher levels in all domains.</div></div><div><h3>Conclusion</h3><div>The findings indicate a need for improved education and training on MIH. Dental institutions and regulatory bodies may use this informati-on to enhance curricula and clinical guidelines, promoting better MIH management in pediatric dentistry.</div></div>","PeriodicalId":19977,"journal":{"name":"Pediatric Dental Journal","volume":"35 3","pages":"Article 100355"},"PeriodicalIF":0.8,"publicationDate":"2025-08-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144763797","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Juvenile ossifying fibroma and aneurysmal bone cyst in the mandible: A case report and mini review of literature","authors":"Fatma Wageeh Attya ,&nbsp;Walaa Hussein Abu El-Ela ,&nbsp;Basma Abdelrahman Ahmed ,&nbsp;Iman Mohamed Helmy","doi":"10.1016/j.pdj.2025.100354","DOIUrl":"10.1016/j.pdj.2025.100354","url":null,"abstract":"<div><h3>Background</h3><div>Hybrid tumors of fibro-osseous and giant cell lesions are rare presentations with few reported cases.</div></div><div><h3>Case presentation</h3><div>Here we present a case of a 9-year-old boy with a swollen right posterior mandible. The lesion was diagnosed as a hybrid Juvenile trabecular ossifying fibroma (JTrOF) with aneurysmal bone cyst (ABC). This article displays the case clinically, radiographically, surgically, and histologically, besides discussing in a mini review the possible etiopathogenesis of this type of hybrid lesions.</div></div><div><h3>Conclusion</h3><div>We reported a rare case of hybrid JTrOF and ABC with a recommendation of further reporting of similar cases for better understanding of the pathogenesis and detecting the best treatment methods.</div></div>","PeriodicalId":19977,"journal":{"name":"Pediatric Dental Journal","volume":"35 3","pages":"Article 100354"},"PeriodicalIF":0.6,"publicationDate":"2025-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144534892","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}