Pain PracticePub Date : 2025-03-01DOI: 10.1111/papr.70018
E Henriksen, J Young, C Power, C Chan
{"title":"What is cancer pain? Investigating attitudes of patients, carers, and health professionals: A cross-sectional survey.","authors":"E Henriksen, J Young, C Power, C Chan","doi":"10.1111/papr.70018","DOIUrl":"10.1111/papr.70018","url":null,"abstract":"<p><strong>Background: </strong>Cancer pain is a prevalent and debilitating symptom that impacts quality of life. Pain management remains challenging; however, due to various barriers, including stigma associated with opioid use, ambiguous roles of clinicians, and diverse attitudes toward pain management among healthcare professionals, patients, and carers.</p><p><strong>Objective: </strong>To explore the attitudes surrounding cancer pain among patients, carers, and health professionals at a tertiary cancer hospital.</p><p><strong>Methods: </strong>A cross-sectional online survey was conducted at the Peter MacCallum Cancer Centre. The survey included demographic measures and statements assessing attitudes toward cancer pain management. Data was analyzed using descriptive statistics in IBM SPSS 29. Ethics approval was granted by the Peter MacCallum HREC.</p><p><strong>Results: </strong>308 participants (153 patients and carers, 155 health professionals) completed the survey. The results revealed significant variability in attitudes surrounding cancer pain and its management. Discrepancies in understanding between health professionals and patients/carers were observed. Differing views on the goals of pain management were revealed, with 51.6% of patients/carers expecting pain elimination compared to 20.6% of health professionals. The roles of clinicians in pain management were also perceived differently, highlighting a lack of clarity in responsibilities. Both groups emphasized the need for increased education on cancer pain and its management.</p><p><strong>Conclusions: </strong>The study revealed substantial variability in attitudes toward cancer pain management among patients, carers, and health professionals. Discrepancies emerged in understanding, with many patients and carers uncertain about the nature of cancer pain, contrasting with health professionals' recognition of its complexity. The terminology distinguishing \"cancer pain\" from \"non-cancer pain\" may contribute to this confusion, suggesting a need to reconsider these semantics. Divergent views on clinician roles and opioid use underscored uncertainties, especially regarding specialist access and prescribing practices. Both groups emphasized the need for education to bridge these gaps, with clearer communication and revised guidelines potentially improving patient outcomes.</p>","PeriodicalId":19974,"journal":{"name":"Pain Practice","volume":"25 3","pages":"e70018"},"PeriodicalIF":2.5,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11883519/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143567917","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pain PracticePub Date : 2025-03-01DOI: 10.1111/papr.70020
Jason Parmar, Aila Malik, Gelilla Zemmedhun, Saba Javed
{"title":"Short-term clinical outcomes and safety of the SpineJack implant system for the treatment of pathological vertebral compression fractures in cancer patients: A retrospective analysis.","authors":"Jason Parmar, Aila Malik, Gelilla Zemmedhun, Saba Javed","doi":"10.1111/papr.70020","DOIUrl":"10.1111/papr.70020","url":null,"abstract":"<p><strong>Background: </strong>The SpineJack implant system is an FDA-approved treatment modality for vertebral compression fractures (VCFs) with reported clinical efficacy comparable to the gold-standard balloon kyphoplasty. Specifically, there is insufficient literature regarding the treatment and safety outcomes of the SpineJack when analyzing a specific subset of patients such as the cancer population.</p><p><strong>Methods: </strong>This is an institutional-level retrospective study at a cancer center on the SpineJack implant consisting of 67 cancer patients (mean age 64 ± 13 years) undergoing a total of 94 SpineJack implantations inserted at 15 thoracolumbar vertebral levels for the treatment of pathologic vertebral compression fractures. The primary outcome of the study was the change in pain score based on the Numeric Rating Scale (NRS) and the secondary outcome was the change in opioid requirement based on morphine milligram equivalents (MME). The average follow-up period was 2 weeks.</p><p><strong>Results: </strong>Post-procedure, a statistically significant decrease in pain severity was observed, with the mean pain score improving from 7.72 ± 2.29 points to 3.45 ± 2.55 points (p-value < 0.0001). Additionally, a reduction in opioid requirement was noted, with a decrease in MME from 66.42 ± 92.66 mg preoperatively to 43.1 ± 60.78 mg (p-value < 0.0001) postoperatively. There was a 1.5% (N = 1) incidence of adjacent level fracture (ALF) reported over an average of 2-week follow-up. The most common intraoperative complication reported was cement extravasation.</p><p><strong>Conclusion: </strong>Overall, treatment of cancer patients with pathologic fractures using the SpineJack procedure resulted in remarkably decreased pain scores, overall decreased MME requirements, a significantly low incidence of ALF (s), and minor intraoperative complications without long-term consequences. The SpineJack procedure is a clinically effective, low-risk treatment option for cancer patients with symptomatic, pathologic VCFs.</p>","PeriodicalId":19974,"journal":{"name":"Pain Practice","volume":"25 3","pages":"e70020"},"PeriodicalIF":2.5,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143573612","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pain PracticePub Date : 2025-03-01DOI: 10.1111/papr.70019
Elisabeth J M Adriaansen, Albert J M van Wijck, Steven P Cohen, Frank J P M Huygen, Mienke Rijsdijk
{"title":"Response to: Do not forget botulinum toxin. Letter to the editor: 8. Herpes zoster and post herpetic neuralgia.","authors":"Elisabeth J M Adriaansen, Albert J M van Wijck, Steven P Cohen, Frank J P M Huygen, Mienke Rijsdijk","doi":"10.1111/papr.70019","DOIUrl":"https://doi.org/10.1111/papr.70019","url":null,"abstract":"","PeriodicalId":19974,"journal":{"name":"Pain Practice","volume":"25 3","pages":"e70019"},"PeriodicalIF":2.5,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143557668","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pain PracticePub Date : 2025-03-01DOI: 10.1111/papr.70016
Maya S Vereen, Vincent J Bidault, Elise Krabbendam, Sanne E Hoeks, Robert Jan Stolker, Maaike Dirckx
{"title":"The effectiveness of liposomal bupivacaine in ultrasound-guided abdominal wall blocks after open abdominal surgery: A systematic review.","authors":"Maya S Vereen, Vincent J Bidault, Elise Krabbendam, Sanne E Hoeks, Robert Jan Stolker, Maaike Dirckx","doi":"10.1111/papr.70016","DOIUrl":"10.1111/papr.70016","url":null,"abstract":"<p><strong>Background and objective: </strong>Thoracic epidural analgesia has traditionally been used for pain management after open abdominal surgery, but its use has declined. The quest for efficient alternatives has resulted in the increasing use of regional techniques. These can be applied as single-shot or continuous blocks using catheters. Long-acting liposomal bupivacaine could preclude the use of catheters. This review aimed to evaluate the effectiveness of ultrasound-guided abdominal wall blocks with liposomal bupivacaine for open abdominal surgery.</p><p><strong>Databases and data treatment: </strong>Medline ALL, Embase, Web of Science Core Collection, Cochrane Central Register of Controlled Trials, and Google Scholar were systematically searched. Screening, data extraction, and quality assessment were done by two independent researchers. Inclusion criteria were (1) liposomal bupivacaine in ultrasound-guided abdominal wall blocks for open abdominal surgery, (2) outcome of pain and/or opioid consumption, (3) patients >18 years, and (4) reports published in English.</p><p><strong>Results: </strong>Of the 1277 studies found, 22 met the inclusion criteria. The Cochrane Risk of Bias (Version 2) tool was used to assess randomized controlled trials. Studies were grouped for clarity. Transversus abdominis plane (TAP) blocks were mostly investigated. Data were heterogenic regarding types of surgery, approach to block placement, anesthetic solution injected, and use of intrathecal morphine (ITM).</p><p><strong>Conclusions: </strong>Patients undergoing cesarean section with neuraxial anesthesia and intrathecal morphine benefit from TAP blocks with liposomal bupivacaine, demonstrating reduced opioid consumption and comparable pain. Evidence for other open abdominal surgeries was inconclusive. Abdominal wall blocks with liposomal bupivacaine could be a viable alternative when epidural analgesia is contraindicated.</p>","PeriodicalId":19974,"journal":{"name":"Pain Practice","volume":"25 3","pages":"e70016"},"PeriodicalIF":2.5,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11837461/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143449908","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pain PracticePub Date : 2025-02-01DOI: 10.1111/papr.70001
Charles Nelson, Chuanhong Liao, Tariq Malik
{"title":"A comparison of MRI and intraoperative measurements to determine interspinous spacer device size.","authors":"Charles Nelson, Chuanhong Liao, Tariq Malik","doi":"10.1111/papr.70001","DOIUrl":"10.1111/papr.70001","url":null,"abstract":"<p><strong>Purpose: </strong>To determine whether preoperative magnetic resonance imaging (MRI) can reliably determine intraoperative measurements in the Vertiflex Interspinous Spacer (ISS) procedure.</p><p><strong>Methods: </strong>Patients who underwent Vertiflex ISS with Lumbar Spinal Stenosis (LSS) and a preoperative MRI available in picture archiving and communication system (PACS) between January 2013 to February 2023 were identified retrospectively from the University of Chicago Medical Center Database. An experienced board-certified pain specialist and well-trained 2nd-year medical student independently performed measurements of the interspinous space where Vertiflex ISSs of various sizes are inserted. MRI measurements were taken blinded to intraoperative measurement and ISS implant size used in the procedure. Pearson's correlation, paired T-test, intraclass correlation coefficients (ICC), absolute agreement, and 2-way random effects model were used to determine the relationships between MRI, intraoperative measurement, and ISS size.</p><p><strong>Results: </strong>A total of 79 patients who underwent the Vertiflex ISS procedure were included in the study. Median Vertiflex ISS size was 10 mm (10-12), mean intraoperative measurement was 11.40 mm (±1.23), and mean MRI measurement was 11.24 mm (±1.44). Mean differences were not significant in intraoperative and MRI measurements (p = 0.271). Pearson's correlation between ISS size and intraoperative measurement was 0.807 (p < 0.001), representing the current best practice model. Pearson's correlation was 0.668 (p < 0.001) between MRI measurement and ISS size and 0.542 (p < 0.001) between MRI and intraoperative measurement. ICC showed good agreement and moderate reliability (0.698) between intraoperative and MRI measurements. Observer interrater ICC agreement of the MRI interspinous space measurement was 0.95 (p < 0.001).</p><p><strong>Conclusions: </strong>Measuring interspinous space on MRI yielded, on average, a value smaller than the intraoperative measurement in Vertiflex ISS procedures, but the mean differences were not significant. Good agreement and moderate reliability were found between observer MRI and surgeon intraoperative measurements, suggesting MRI can evaluate the intraoperative space for the Vertiflex ISS procedure. Preoperative MRI measurement may help decrease complications by aiding in surgical decision-making through providing a reference for intraoperative measurements. Further prospective study is necessary to determine if preoperative MRI measurement can predict and potentially replace the need for intraoperative measurement.</p>","PeriodicalId":19974,"journal":{"name":"Pain Practice","volume":"25 2","pages":"e70001"},"PeriodicalIF":2.5,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11748108/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143009756","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pain PracticePub Date : 2025-02-01DOI: 10.1111/papr.70010
Matthew Chung, Alaa Abd-Elsayed
{"title":"Comparative efficacy of closed-loop spinal cord stimulation and dorsal root ganglion stimulation through combination trialing for cancer pain - A retrospective case series.","authors":"Matthew Chung, Alaa Abd-Elsayed","doi":"10.1111/papr.70010","DOIUrl":"10.1111/papr.70010","url":null,"abstract":"<p><strong>Objective: </strong>To compare the efficacy of closed-loop spinal cord stimulation (CL-SCS) and dorsal root ganglion (DRG) stimulation in managing chronic cancer-related pain.</p><p><strong>Material/methods: </strong>A retrospective review was conducted with IRB exemption for four patients with cancer-related pain who underwent combination stimulator trials. Patients were trialed with both CL-SCS and DRG stimulation for 8-10 days, with assessments of pain relief, functional improvement, sleep improvement, pain medication changes, and overall satisfaction.</p><p><strong>Results: </strong>All four patients reported significant relief and functional improvement with both CL-SCS and DRG stimulations. CL-SCS provided a range of 12.9-19.6 million adjustments during the trial period. Neural dose was delivered at a median dose ratio of 1.35 and median dose accuracy of 4.9 μV. Patients 1-3 preferred CL-SCS for paresthesia-based stimulation, having the potential to expand pain coverage, full-body MRI compatibility, and real-time automated adjustment features. Patient 4 favored DRG for its ability to provide slightly greater relief, over one aspect of his pain area, despite having comparable coverage with CL-SCS.</p><p><strong>Conclusions: </strong>The consistent and adaptable delivery of CL-SCS may bridge the gap in efficacy that DRG therapy has held over traditional dorsal column stimulation for historically complex and focal conditions that suggests further investigation.</p>","PeriodicalId":19974,"journal":{"name":"Pain Practice","volume":"25 2","pages":"e70010"},"PeriodicalIF":2.5,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143009875","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pain PracticePub Date : 2025-02-01DOI: 10.1111/papr.70003
Aaron Burshtein, Paul Shekane
{"title":"Factors associated with patient no-show rates in an academic pain management practice.","authors":"Aaron Burshtein, Paul Shekane","doi":"10.1111/papr.70003","DOIUrl":"10.1111/papr.70003","url":null,"abstract":"<p><strong>Objectives: </strong>Chronic pain is a debilitating, multifactorial condition. The purpose of this study was to examine patient characteristics of those who did not show up for their scheduled first pain medicine appointment in order to identify factors that may improve access to care.</p><p><strong>Methods: </strong>This was a retrospective analysis of 810 patients from a single-center academic pain management clinic between January 1, 2022, and December 31, 2023.</p><p><strong>Results: </strong>Overall no-show rate was 57%. There was a mean of 133 days (4.3 months) from scheduling to the appointment date. Patients age ≤ 30 years had the highest no-show rate (69%), and those ≥81 years had the lowest (49%). Hispanic and Caucasian patients had similar no-show rates (59% and 57%, respectively) and Asian patients had lower rate (41%). Referral from another specialty had a significantly lower no-show rate (36% vs. 89%, p < 0.001). The presence of referral (p < 0.001) was a significant predictor of lower no-show rates. Of the 191 patients with low back pain, internal medicine (38.7%) was the most referring specialty.</p><p><strong>Discussion: </strong>High no-show rates were present particularly among younger patients. Having a referral from another specialty was an independent predictor of lower no-show rates.</p>","PeriodicalId":19974,"journal":{"name":"Pain Practice","volume":"25 2","pages":"e70003"},"PeriodicalIF":2.5,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143009877","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pain PracticePub Date : 2025-02-01DOI: 10.1111/papr.70011
Danielle L Sarno, Ashley E Gureck, Alejandra Cardenas-Rojas, Marissa Eckley, Kevin Vu, Jennifer Kurz, Melanie Fu, Zacharia Isaac, Edward Phillips, Bridget Chin, Daniel S Barron
{"title":"An interdisciplinary virtual group program addressing the FINER points of chronic pain management: An exploratory analysis of functional outcomes.","authors":"Danielle L Sarno, Ashley E Gureck, Alejandra Cardenas-Rojas, Marissa Eckley, Kevin Vu, Jennifer Kurz, Melanie Fu, Zacharia Isaac, Edward Phillips, Bridget Chin, Daniel S Barron","doi":"10.1111/papr.70011","DOIUrl":"10.1111/papr.70011","url":null,"abstract":"<p><strong>Objectives: </strong>Chronic pain is multifactorial and has large social and economic costs. Comprehensive pain management through an interdisciplinary approach addressing the biopsychosocial model of pain is beneficial. The purpose of this study was to assess the feasibility and functional outcomes following participation in the 8-week virtual interdisciplinary Functional Integrative Restoration (FINER) program.</p><p><strong>Design: </strong>Cohort study.</p><p><strong>Setting: </strong>Virtual platform (Zoom) utilized by participants and clinicians within a large academic institution.</p><p><strong>Subjects: </strong>44 individuals with chronic pain meeting study criteria who participated in the virtual FINER program from September 2021 to April 2023 were included in final analysis.</p><p><strong>Methods: </strong>Participants attended twice weekly seminars and group sessions focused on pain education, lifestyle medicine, integrative medicine, and psychological therapies virtually and completed pre- and post-program surveys. Outcomes included the Pain Catastrophizing Scale (PCS), Tampa Scale of Kinesiophobia (TSK), and Patient-Reported Outcomes Measurement Information System-29 (PROMIS-29). Qualitative feedback was also obtained.</p><p><strong>Results: </strong>From September 2021 to April 2023, 44 adult FINER participants with chronic low back and/or neck pain completed pre- and post-intervention surveys. We observed significant improvements in PCS, TSK, and various domains of the PROMIS-29, including pain interference, participation, physical function, and sleep, with modest effect sizes.</p><p><strong>Conclusions: </strong>The FINER program reduced self-reported functional outcomes related to the participants' chronic pain. Positive qualitative feedback from FINER participants suggested mental and physical health benefits. Future investigation will include a larger cohort and will deploy active (patient-reported outcomes) and passive (mobility and sociability) digital measures to further characterize functional changes.</p>","PeriodicalId":19974,"journal":{"name":"Pain Practice","volume":"25 2","pages":"e70011"},"PeriodicalIF":2.5,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143256027","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The efficacy of pulsed radiofrequency ablation of the dorsal root ganglion in the setting of failed spinal neuromodulation: A case report.","authors":"Abhijeet Rastogi, Kovosh Dastan, Sujana Sunkara, Peyton LaRosa","doi":"10.1111/papr.70004","DOIUrl":"10.1111/papr.70004","url":null,"abstract":"<p><p>Radiofrequency ablation (RFA) is an interventional procedure that has been used to treat chronic back pain for over 50 years; this unique case report demonstrates the effectiveness of pulsed radiofrequency ablation (PRFA) on the dorsal root ganglion (DRG) in the treatment of chronic radicular pain (Russo et al., 2021, J Pain Res, 14, 3897). The RFA provides pain relief by using thermal energy to disrupt peripheral nerves carrying nociceptive signals back to the central nervous system (Abd-Elsayed et al. 2020, Pain Ther, 9, 709). However, there is a lack of literature about the safety and efficacy of PRFA of the DRG.</p>","PeriodicalId":19974,"journal":{"name":"Pain Practice","volume":"25 2","pages":"e70004"},"PeriodicalIF":2.5,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143047644","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}