Pakistan journal of pharmaceutical sciences最新文献

Effectiveness of ginkgolides on neurological function and nutritional status of patients with cerebral hemorrhage. 银杏内酯对脑出血患者神经功能和营养状况的疗效。

IF 0.7 4区医学

Pakistan journal of pharmaceutical sciences Pub Date : 2025-01-01

Sisi Chen, Xiaoli Feng

{"title":"Effectiveness of ginkgolides on neurological function and nutritional status of patients with cerebral hemorrhage.","authors":"Sisi Chen, Xiaoli Feng","doi":"","DOIUrl":"","url":null,"abstract":"Cerebral hemorrhage (CH) is characterized by acute onset, rapid progression and poor prognosis, posing a great potential threat to the health of patients. Ginkgolides, an excellent natural perpend, have the functions of vasodilation, anti-inflammation, anti-oxidation and memory and cognitive enhancement and the rich trace elements help improve the nutritional status of the human body, which is an important guarantee for the prognosis and health of CH patients. In this study, we observed the therapeutic efficacy of Ginkgolides combined with all-in-one nursing care for CH, thus providing a new reference for the future treatment of CH. We divided 100 patients with CH into a study group receiving Ginkgolides combined with all-in-one nursing care and a control group receiving all-in-one nursing care and compared their neurological and cognitive function, inflammatory response and nutritional status. The results found that ginkgolides combined with all-in-one nursing care better enhanced the neurological and cognitive functions of CH patients and inhibited inflammatory responses. Besides, ginkgolides significantly promoted the increase of nutritional protein levels in CH patients, better ensuring their health. Therefore, we recommend to popularize the use of ginkgolides combined with all-in-one nursing care in the treatment of CH in the future.","PeriodicalId":19971,"journal":{"name":"Pakistan journal of pharmaceutical sciences","volume":"38 1","pages":"83-88"},"PeriodicalIF":0.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143795993","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Relationship between serum CEACAM1 levels and prognosis and temozolomide chemotherapy sensitivity in patients undergoing neuroendoscopic transsphenoidal pituitary tumor resection. 接受神经内镜经蝶垂体瘤切除术的患者血清CEACAM1水平与预后和替莫唑胺化疗敏感性之间的关系

IF 0.7 4区医学

Pakistan journal of pharmaceutical sciences Pub Date : 2025-01-01

Chong Chen Ma, Er Ping He, Yue Qing Zhang, Yong Jing Wang, Chun Ming Zhu, Xuan Yu

{"title":"Relationship between serum CEACAM1 levels and prognosis and temozolomide chemotherapy sensitivity in patients undergoing neuroendoscopic transsphenoidal pituitary tumor resection.","authors":"Chong Chen Ma, Er Ping He, Yue Qing Zhang, Yong Jing Wang, Chun Ming Zhu, Xuan Yu","doi":"","DOIUrl":"","url":null,"abstract":"Pituitary tumors are common intracranial neoplasms with complex pathogenesis. Temozolomide (TMZ) has shown potential in treatment, but its efficacy and related biomarkers require further investigation. This study explores the relationship between serum CEACAM1 levels, prognosis after neuroendoscopic transsphenoidal pituitary tumor resection, and TMZ sensitivity. A retrospective analysis of 70 patients who underwent surgery from 2020 to 2022 was conducted. Patients were classified into high- and low-CEACAM1 groups. Baseline characteristics showed no significant differences (P>0.05). After six months, patients with poor prognosis had significantly higher preoperative CEACAM1 levels (P<0.05). TMZ-resistant patients also had elevated levels (P<0.05). The AUC of preoperative CEACAM1 for predicting prognosis was 0.716 (cutoff: 5857.5 pg/mL) and for TMZ resistance was 0.742 (cutoff: 6431 pg/mL). High preoperative CEACAM1 levels are associated with poor prognosis and TMZ resistance, serving as a potential biomarker to guide clinical evaluation and treatment.","PeriodicalId":19971,"journal":{"name":"Pakistan journal of pharmaceutical sciences","volume":"38 1","pages":"165-173"},"PeriodicalIF":0.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143796010","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Impact of tislelizumab combined with albumin-bound paclitaxel and carboplatin on intestinal flora and gastrointestinal toxicities in advanced lung cancer. tislelizumab联合白蛋白结合紫杉醇和卡铂对晚期肺癌患者肠道菌群和胃肠道毒性的影响。

IF 0.7 4区医学

Pakistan journal of pharmaceutical sciences Pub Date : 2025-01-01

Kai Feng, Tianwei Liu, Ruihua Ren, Yanan Zhao, Haiyang Li, Jiyun Wang

引用次数: 0

Combination therapy with Baofukang suppositories and promestriene cream for postmenopausal atrophic vaginitis: A randomized controlled trial. 保妇康栓和丙三烯乳膏联合治疗绝经后萎缩性阴道炎：随机对照试验。

IF 0.7 4区医学

Pakistan journal of pharmaceutical sciences Pub Date : 2025-01-01

Jingjing Wang, Shuya Yang, Shujun Yan

{"title":"Combination therapy with Baofukang suppositories and promestriene cream for postmenopausal atrophic vaginitis: A randomized controlled trial.","authors":"Jingjing Wang, Shuya Yang, Shujun Yan","doi":"","DOIUrl":"","url":null,"abstract":"Postmenopausal atrophic vaginitis is a prevalent condition that significantly impacts the quality of life. This study aimed to evaluate the efficacy and safety of combining Baofukang suppositories with Promestriene cream in treating this condition, with a particular focus on clinical outcomes and endometrial thickness. Sixty-eight patients underwent random allocation into either the control group (Baofukang suppositories) or the observational group (Baofukang suppositories and Promestriene cream). Endometrial thickness was measured using transvaginal ultrasound and clinical indicators, including symptom resolution time, vaginal cleanliness, and adverse reactions, were assessed. The observational group showed a higher effective rate (97.06% vs. 79.41%, P<0.05) and faster symptom relief (P<0.05), with significant improvements in vaginal cleanliness and symptom scores (P<0.05). No significant differences in endometrial thickness or adverse reactions were observed (P<0.05). Combining Baofukang suppositories with Promestriene cream offers an effective and safe therapeutic option for postmenopausal atrophic vaginitis, promoting superior symptom recovery without compromising endometrial safety.","PeriodicalId":19971,"journal":{"name":"Pakistan journal of pharmaceutical sciences","volume":"38 1","pages":"151-156"},"PeriodicalIF":0.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143795905","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Pharmacological insights into Azadirachta indica fruit: GC-MS Profiling and evaluation of key bioactivities on experimental animals. 对 Azadirachta indica 果实的药理研究：GC-MS 图谱分析和对实验动物关键生物活性的评估。

IF 0.7 4区医学

Pakistan journal of pharmaceutical sciences Pub Date : 2025-01-01

Mariam Razzak, Azra Riaz, Muhammad Ali Rajput, Shahana Wahid, Ali Alqahtani, Saira Saeed Khan, Maham Nawaz, Anusha Ahmed

{"title":"Pharmacological insights into Azadirachta indica fruit: GC-MS Profiling and evaluation of key bioactivities on experimental animals.","authors":"Mariam Razzak, Azra Riaz, Muhammad Ali Rajput, Shahana Wahid, Ali Alqahtani, Saira Saeed Khan, Maham Nawaz, Anusha Ahmed","doi":"","DOIUrl":"","url":null,"abstract":"Azadirachta indica, fruit with significant therapeutic potential, was evaluated using a multidimensional approach to systematically evaluate its pharmacological spectrum covering antimicrobial, antifungal, anti-inflammatory, analgesic, muscle-relaxant and sleep-inducing effects using in vitro and in vivo models. The study found that fruit extract, when administered at different doses, showed significant antibacterial effects against Gram-positive and Gram-negative bacteria along with a highly significant antifungal effect against Aspergillus niger that might be due to identified azol compounds.‎ Azadirachta indica extract showed significant anti-inflammatory effects at doses of 200 and 400mg/Kg, reducing paw oedema volume and exhibiting analgesic and muscle relaxant activity. Unique findings included significant muscle relaxation and enhanced locomotor activity observed specifically at 400mg/Kg on the 7th and 14th days. Azadirachta indica showed significantly increased sleep duration and reduced sleep onset time in Na-thiopental-induced sleep tests at doses of 200 and 400mg/Kg. ‎Through GC-MS analysis, bioactive compounds, including 2,3-propanetriol, 7-methoxy-‎‎1,3,4,5-tetrahydrobenzo[b]azepin-2-one, piperazine and 4-amino-4,5-dihydro-1H-1,2,4-‎triazol-5-one, were identified, which likely contribute to the observed pharmacological ‎activities.‎ This study first reports Azadirachta indica's muscle-relaxant and sleep-enhancing effects, expanding its known therapeutic potential.","PeriodicalId":19971,"journal":{"name":"Pakistan journal of pharmaceutical sciences","volume":"38 1","pages":"139-150"},"PeriodicalIF":0.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143796007","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The effects of dexmedetomidine and remimazolam on spinal anesthesia in patients with anxiety disorder: A retrospective case-control study on intraoperative sedation quality and postoperative cognitive function. 右美托咪定和雷马唑仑对焦虑障碍患者脊髓麻醉的影响：术中镇静质量和术后认知功能的回顾性病例对照研究。

IF 0.7 4区医学

Pakistan journal of pharmaceutical sciences Pub Date : 2025-01-01

Xinyu Yuan, Fei Liang

{"title":"The effects of dexmedetomidine and remimazolam on spinal anesthesia in patients with anxiety disorder: A retrospective case-control study on intraoperative sedation quality and postoperative cognitive function.","authors":"Xinyu Yuan, Fei Liang","doi":"","DOIUrl":"","url":null,"abstract":"Anxiety disorder patients are accompanied by significant dysfunction and other problems, clinical treatment faces great challenges. The aim of this study is to investigate the effects of dexmedetomidine and remimazolam on spinal anesthesia in anxiety disorder patients, to provide a clinical reference point. 80 anxiety disorder patients coming to our hospital for intrathecal anaesthesia surgery from June 2022 to June 2024 were divided into control group (n=40) and study group (n=40). Remimazolam was used in both groups and dexmedetomidine was added in study group. The heart rates (HR) and means of arterial pressures (MAP), Ramsay scores, visual analog scale (VAS) and hamilton analysis of metabolic anxiety scale (HAMA) scores, mini-mental state examination (MMSE), montreal cognitive assessment scale (MoCA) scores, serum platelet activating factors (PAF) and interferon gamma (IFN-γ) and adverse reactions were compared among the both groups. Compared to control group, HR and MAP levels, MMSE and MoCA scores, and IFN-γ levels were significantly increased, and Ramsay scores, VAS scores, HAMA scores and PAF levels were significantly decreased in the study group (P<0.05). No significant difference in the adverse reaction incidence of the both groups (P>0.05). Spinal anesthesia with dexmedetomidine and remimazolam provides better anesthesia in anxiety disorders patients.","PeriodicalId":19971,"journal":{"name":"Pakistan journal of pharmaceutical sciences","volume":"38 1","pages":"175-183"},"PeriodicalIF":0.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143987256","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Study on the effect of Western medicine caltrate D combined with traditional Chinese medicine eight section brocade practice therapy on preventing postmenopausal osteoporosis. 西药钙化D联合中药八节锦疗法预防绝经后骨质疏松的疗效研究。

IF 0.7 4区医学

Pakistan journal of pharmaceutical sciences Pub Date : 2025-01-01

Xiaoyu Lan, Hongyan Sun, Kun Shi, Xiaohong Sun, Taoran Wang, Hui Wang

{"title":"Study on the effect of Western medicine caltrate D combined with traditional Chinese medicine eight section brocade practice therapy on preventing postmenopausal osteoporosis.","authors":"Xiaoyu Lan, Hongyan Sun, Kun Shi, Xiaohong Sun, Taoran Wang, Hui Wang","doi":"","DOIUrl":"","url":null,"abstract":"Caltrate D is a commonly used drug in the treatment of postmenopausal osteoporosis (PMOP), but the effect of single application is not ideal. Therefore, to investigate the eight section brocade therapy combined with caltrate D effect in preventing and treating PMOP. From January 2021 to June 2022, 110 postmenopausal women with decreased bone mass were selected and randomized into group A (n = 54) and group B (n = 56). The both group receiving caltrate D treatment and group B added receiving Chinese medicine eight section brocade therapy. Bone mineral density (BMD), WHOQOL-BREF score and incidence of PMOP were compared in both groups. The bone metabolism indexes [serum calcium, phosphorus, alkaline phosphatase (ALP)], bone formation indexes [serum Procollagen I N-Terminal Propeptide (PINP), type 1 collagen C-terminal cross-linked telopeptides (β-CTX)] were detected in both groups. After treatment, lumbar BMD, femoral neck BMD, serum calcium level and WHOQOL-BREF score in group B were significantly higher compared to group A, serum phosphorus and ALP levels, PMOP recurrence rate decreased significantly and no significant difference in serum PINP and β-CTX levels in both groups. This combination therapy is significantly effective and provides a new reference for the clinical treatment of PMOP.","PeriodicalId":19971,"journal":{"name":"Pakistan journal of pharmaceutical sciences","volume":"38 1","pages":"1-6"},"PeriodicalIF":0.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143634452","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Salvia miltiorrhiza adjuvant therapy facilitates cardiac function recovery in patients with myocardial infarction. 丹参辅助治疗对心肌梗死患者心功能恢复有促进作用。

IF 0.7 4区医学

Pakistan journal of pharmaceutical sciences Pub Date : 2025-01-01

Mei Zhang, Ying Liu, Xingcheng Sun, Xiaoqing Zhang, Libo Hua

{"title":"Salvia miltiorrhiza adjuvant therapy facilitates cardiac function recovery in patients with myocardial infarction.","authors":"Mei Zhang, Ying Liu, Xingcheng Sun, Xiaoqing Zhang, Libo Hua","doi":"","DOIUrl":"","url":null,"abstract":"Myocardial infarction (MI), a leading cause of global mortality, often leads to heart failure and impaired quality of life. This randomized controlled trial evaluated Salvia miltiorrhiza (SM), a traditional Chinese herb containing bioactive compounds like tanshinone IIA and salvianolic acid A, as an adjunct therapy for acute MI. SM is known for anti-inflammatory, antioxidant, anticoagulant and microcirculatory benefits. In the study, 120 MI patients were divided into two groups: routine treatment (RT) and RT plus SM injection. After two weeks, the SM group demonstrated significantly increased left ventricular ejection fraction (LVEF) and reduced left ventricular end-systolic and end-diastolic diameters (LVESD, LVEDD) compared to RT (P<0.001). Hemodynamic parameters-cardiac output (CO), cardiac index (CI), and stroke volume (SV) also improved markedly in the SM group. Additionally, SM enhanced vascular endothelial function and lowered serum markers of myocardial injury. These findings suggest SM supplementation synergizes with conventional therapies to accelerate cardiac functional recovery and hemodynamic stabilization in MI patients. The study highlights SM's potential as a safe, effective adjuvant treatment for MI, warranting further clinical exploration.","PeriodicalId":19971,"journal":{"name":"Pakistan journal of pharmaceutical sciences","volume":"38 1","pages":"45-53"},"PeriodicalIF":0.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143634451","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Exploring the antidepressant and anxiolytic effects of Desmostachya bipinnata: Evidence from animal models and in-silico studies. 探讨石竹的抗抑郁和抗焦虑作用：来自动物模型和计算机研究的证据。

IF 0.7 4区医学

Pakistan journal of pharmaceutical sciences Pub Date : 2025-01-01

Muhammad Muzammil Nazir, Muhammad Arif, Mahnoor Arif, Iqra Farzeen, Anjum Khursheed, Asma Ashraf, Hareem Noor, Muhammad Haneef, Abdulhakeem S Alamri, Majid Alhomrani, Walaa F Alsanie, Hammad Saleem

{"title":"Exploring the antidepressant and anxiolytic effects of Desmostachya bipinnata: Evidence from animal models and in-silico studies.","authors":"Muhammad Muzammil Nazir, Muhammad Arif, Mahnoor Arif, Iqra Farzeen, Anjum Khursheed, Asma Ashraf, Hareem Noor, Muhammad Haneef, Abdulhakeem S Alamri, Majid Alhomrani, Walaa F Alsanie, Hammad Saleem","doi":"","DOIUrl":"","url":null,"abstract":"The purpose of this study was to assess the ethanolic extract of Desmostachya bipinnata (EEDBR)'s sedative and antidepressant properties in Swiss albino mice. The extract was given to Swiss albino mice in single doses of 100, 200 and 400mg/kg of body weight for different biological tests. In the open field test, the diazepam group and the 400mg/kg dosage group spent more time in the centre zone than the control group. The 400mg/kg dosage and diazepam group had no discernible effect on centre time response. Additionally, a dosage of 100mg/kg exhibits a significant impact of 44±3.60. Compared to treated with EEDBR, those given with standard control Diazepam (1mg/kg) had higher head dips. At all dosages, there was a substantial decrease in locomotor activity in HCT as compared to the control group at all time intervals (between 30 and 120 minutes). Diazepam, the positive control, significantly lowers locomotor activity. EEDBR reduced sadness and anxiety in a dose-dependent way. Higher dosages of EEDBR result in noticeably stronger antidepressant effects, indicating a dose-dependent connection. For the molecules isopulegone, geranyl isovalerate and eucalyptol, the in-silico docking scores for Cyclooxygenase-1 and Cyclooxygenase-2 are -8.2, -6.2, -8.4 and -8.9, -7.2, -7.6 respectively.","PeriodicalId":19971,"journal":{"name":"Pakistan journal of pharmaceutical sciences","volume":"38 1","pages":"279-289"},"PeriodicalIF":0.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144009041","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effects of saponin extract from Panax notoginseng on hyperlipidemic mice. 三七皂苷提取物对高脂血症小鼠的影响。

IF 0.7 4区医学

Pakistan journal of pharmaceutical sciences Pub Date : 2025-01-01

Zheng-Yong Yu, Ya-Juan Luo, Tai-Hui Yang, Wen-Bo Zeng, Heng Liu, Wen-Feng Xin, Guang-Quan Feng

{"title":"Effects of saponin extract from Panax notoginseng on hyperlipidemic mice.","authors":"Zheng-Yong Yu, Ya-Juan Luo, Tai-Hui Yang, Wen-Bo Zeng, Heng Liu, Wen-Feng Xin, Guang-Quan Feng","doi":"","DOIUrl":"","url":null,"abstract":"To investigate the impact of the Panax notoginseng saponin extract on hyperlipidaemic mice. We developed a hyperlipidemia model in mouse through the administration of a high-fat diet. We conducted weekly measurements of body weight, serum total cholesterol (TC), triglycerides (TG), low-density lipoprotein cholesterol (LDL-C) and highdensity lipoprotein cholesterol (HDL-C). Additionally, serum levels of Apolipoprotein A (APOA) and Apolipoprotein B (APOB) were determined post-feeding. We assessed pathological liver tissue damage in mice, as well as examined malondialdehyde (MDA) levels and superoxide dismutase (SOD) activity in liver tissue. Immunohistochemical analysis was conducted to detect the expression levels of heme oxygenase-1 (HO-1) and nuclear factor erythroid 2-related factor 2 (Nrf2) proteins within liver tissues. Administration of Panax notoginseng saponin extract led to a reduction in body weight, liver index, and histopathological scores among mice. Additionally, there was a significant reduction in TC, TG and LDL-C levels, accompanied by an increase in HDL-C levels. Additionally, an increase in hepatic SOD activity and a decrease in MDA content were observed in the liver homogenates of mice. Furthermore, the expression levels of HO-1 and Nrf2 proteins were upregulated in liver tissue. These findings suggest that Panax notoginseng saponin extracts may ameliorate high-fat diet-induced hyperlipidemia.","PeriodicalId":19971,"journal":{"name":"Pakistan journal of pharmaceutical sciences","volume":"38 1","pages":"207-217"},"PeriodicalIF":0.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144006250","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0