{"title":"氯吡格雷对脑卒中后运动障碍患者神经康复的辅助作用。","authors":"Lan Chen, Jianqiu Gong","doi":"10.36721/PJPS.2025.38.5.REG.13260.1","DOIUrl":null,"url":null,"abstract":"<p><p>This study investigates the auxiliary effect of clopidogrel on neurorehabilitation in patients with post-stroke movement disorders to evaluate its efficacy in rehabilitation treatment. A randomized controlled study is conducted, dividing patients into a conventional treatment group and a clopidogrel treatment group. The Fugl-Meyer score, Barthel Index, and NIHSS score are employed to assess and compare the patients' motor function, daily activity ability, and neurological function before and after treatment. The scores for the Experimental Group exceed those of the Control Group for all measures, with p-values less than 0.05 or 0.01. These results indicate that the clopidogrel treatment group outperforms the conventional treatment group in stroke rehabilitation. This study examines clopidogrel's auxiliary effect through a long-term experiment on the rehabilitation of patients with post-stroke movement disorders, offering new treatment ideas and methods for clinical practice.</p>","PeriodicalId":19971,"journal":{"name":"Pakistan journal of pharmaceutical sciences","volume":"38 5","pages":"1567-1576"},"PeriodicalIF":0.7000,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Auxiliary effect of clopidogrel on neurological rehabilitation in patients with post-stroke motor disorders.\",\"authors\":\"Lan Chen, Jianqiu Gong\",\"doi\":\"10.36721/PJPS.2025.38.5.REG.13260.1\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>This study investigates the auxiliary effect of clopidogrel on neurorehabilitation in patients with post-stroke movement disorders to evaluate its efficacy in rehabilitation treatment. A randomized controlled study is conducted, dividing patients into a conventional treatment group and a clopidogrel treatment group. The Fugl-Meyer score, Barthel Index, and NIHSS score are employed to assess and compare the patients' motor function, daily activity ability, and neurological function before and after treatment. The scores for the Experimental Group exceed those of the Control Group for all measures, with p-values less than 0.05 or 0.01. These results indicate that the clopidogrel treatment group outperforms the conventional treatment group in stroke rehabilitation. This study examines clopidogrel's auxiliary effect through a long-term experiment on the rehabilitation of patients with post-stroke movement disorders, offering new treatment ideas and methods for clinical practice.</p>\",\"PeriodicalId\":19971,\"journal\":{\"name\":\"Pakistan journal of pharmaceutical sciences\",\"volume\":\"38 5\",\"pages\":\"1567-1576\"},\"PeriodicalIF\":0.7000,\"publicationDate\":\"2025-09-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Pakistan journal of pharmaceutical sciences\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.36721/PJPS.2025.38.5.REG.13260.1\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"PHARMACOLOGY & PHARMACY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Pakistan journal of pharmaceutical sciences","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.36721/PJPS.2025.38.5.REG.13260.1","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"PHARMACOLOGY & PHARMACY","Score":null,"Total":0}
Auxiliary effect of clopidogrel on neurological rehabilitation in patients with post-stroke motor disorders.
This study investigates the auxiliary effect of clopidogrel on neurorehabilitation in patients with post-stroke movement disorders to evaluate its efficacy in rehabilitation treatment. A randomized controlled study is conducted, dividing patients into a conventional treatment group and a clopidogrel treatment group. The Fugl-Meyer score, Barthel Index, and NIHSS score are employed to assess and compare the patients' motor function, daily activity ability, and neurological function before and after treatment. The scores for the Experimental Group exceed those of the Control Group for all measures, with p-values less than 0.05 or 0.01. These results indicate that the clopidogrel treatment group outperforms the conventional treatment group in stroke rehabilitation. This study examines clopidogrel's auxiliary effect through a long-term experiment on the rehabilitation of patients with post-stroke movement disorders, offering new treatment ideas and methods for clinical practice.
期刊介绍:
Pakistan Journal of Pharmaceutical Sciences (PJPS) is a peer reviewed multi-disciplinary pharmaceutical sciences journal. The PJPS had its origin in 1988 from the Faculty of Pharmacy, University of Karachi as a biannual journal, frequency converted as quarterly in 2005, and now PJPS is being published as bi-monthly from January 2013.
PJPS covers Biological, Pharmaceutical and Medicinal Research (Drug Delivery, Pharmacy Management, Molecular Biology, Biochemical, Pharmacology, Pharmacokinetics, Phytochemical, Bio-analytical, Therapeutics, Biotechnology and research on nano particles.