Pediatric Allergy and Immunology最新文献

{"title":"Age-specific issues of accidental exposure in pediatric food allergy: A multicenter survey.","authors":"Toshiko Itazawa, Moeka Oguri, Taisuke Kato, Muneyuki Shimizu, Motokazu Nakabayashi, Takuya Wada, Yasunori Ito, Osamu Higuchi, Junko Yamamoto, Miwa Kawashiri, Yoichi Onoue, Miki Takao, Yoko Adachi, Gyokei Murakami, Yuichi Adachi","doi":"10.1111/pai.70017","DOIUrl":"https://doi.org/10.1111/pai.70017","url":null,"abstract":"","PeriodicalId":19929,"journal":{"name":"Pediatric Allergy and Immunology","volume":"35 12","pages":"e70017"},"PeriodicalIF":4.3,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142838752","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Health-related quality of life difference between children with hen's egg-induced enterocolitis syndrome and those with IgE-mediated allergy.","authors":"Naoki Kajita, Makoto Kaneko, Go Kusakawa, Kumiko Morita, Koichi Yoshida","doi":"10.1111/pai.70010","DOIUrl":"https://doi.org/10.1111/pai.70010","url":null,"abstract":"","PeriodicalId":19929,"journal":{"name":"Pediatric Allergy and Immunology","volume":"35 12","pages":"e70010"},"PeriodicalIF":4.3,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142790648","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"High rate of tolerance for quail's egg in hen's egg FPIES patients.","authors":"Naoki Kajita, Go Kusakawa, Keiko Hirao, Shoko Yokoyama, Emi Morikawa, Kumiko Morita, Masami Narita, Koichi Yoshida","doi":"10.1111/pai.70009","DOIUrl":"https://doi.org/10.1111/pai.70009","url":null,"abstract":"","PeriodicalId":19929,"journal":{"name":"Pediatric Allergy and Immunology","volume":"35 12","pages":"e70009"},"PeriodicalIF":4.3,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142786409","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reply to Wang et al.","authors":"Alicia Adiwidjaja, Justin Jones, Patrick Ross, Matthew Keefer, Margaret J Klein, Jonathan M Tan","doi":"10.1111/pai.70015","DOIUrl":"https://doi.org/10.1111/pai.70015","url":null,"abstract":"","PeriodicalId":19929,"journal":{"name":"Pediatric Allergy and Immunology","volume":"35 12","pages":"e70015"},"PeriodicalIF":4.3,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142838754","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Duration of food protein-induced allergic proctocolitis (FPIAP) and the role of intestinal microbiota.","authors":"G N Vallianatou, N Douladiris, L Mageiros, E Manousakis, V Zisaki, M Galani, P Xepapadaki, S Taka, N G Papadopoulos","doi":"10.1111/pai.70008","DOIUrl":"10.1111/pai.70008","url":null,"abstract":"<p><strong>Background: </strong>Food protein-induced allergic proctocolitis (FPIAP) is the leading cause of rectal bleeding in infants. Tolerance is presumed to develop until the first year of age, although natural history studies are scarce, making the determination of the ideal duration for any intervention, challenging. Intestinal microbiota (IM) is crucial in food allergy development; however, data for FPIAP remain limited. This study aimed to assess FPIAP remission after 3 months of milk avoidance and its correlation with IM longitudinal changes.</p><p><strong>Methods: </strong>A prospective observational study of infants aged ≤6 months with a diagnosis of FPIAP. After 3 months of management according to a clinical algorithm, infants were subjected to a milk challenge using either a cow (CM) or a goat (GM) milk formula in a random order. Stool samples were collected longitudinally for microbiome analysis.</p><p><strong>Results: </strong>Out of 61 infants, 57 were challenged (29 with CM, 28 with GM). Of these, 55 (96.5%) achieved tolerance, with no difference in tolerance rates between CM (28/29) and GM (27/28). The average age of tolerance development was 6.3 months. Enterobacteriaceae clusters (Klebsiella- and Shigella-dominated) were most often represented in samples from symptomatic infants. In contrast, Bacteroides and Bifidobacteria clusters emerged later, in apparently healthy infants.</p><p><strong>Conclusion: </strong>A 3-month intervention was sufficient for almost all infants to achieve tolerance. GM was tolerated equally well to CM. Symptomatic FPIAP is associated with immature enterotypes, while disease remission coincides with microbiome changes in time.</p>","PeriodicalId":19929,"journal":{"name":"Pediatric Allergy and Immunology","volume":"35 12","pages":"e70008"},"PeriodicalIF":4.3,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11616471/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142771250","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Eczematoid lesions and extensive molluscum contagiosum in a child with novel CARMIL2 defect.","authors":"Sathish Kumar Loganathan, Sumit Goel, Sanjib Mondal, Daniel Leung, Koon Wing Chan, Yu Lung Lau, Pandiarajan Vignesh, Amit Rawat","doi":"10.1111/pai.70003","DOIUrl":"https://doi.org/10.1111/pai.70003","url":null,"abstract":"","PeriodicalId":19929,"journal":{"name":"Pediatric Allergy and Immunology","volume":"35 12","pages":"e70003"},"PeriodicalIF":4.3,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142771253","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Low serum vitamin D is associated with egg white sensitization at age 1 year.","authors":"Fumiya Yamaide, Madoka Tomura, Mamoru Satoh, Yuzuka Kunii, Taiji Nakano, Fumio Nomura, Naoki Shimojo","doi":"10.1111/pai.70021","DOIUrl":"https://doi.org/10.1111/pai.70021","url":null,"abstract":"","PeriodicalId":19929,"journal":{"name":"Pediatric Allergy and Immunology","volume":"35 12","pages":"e70021"},"PeriodicalIF":4.3,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142895837","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mulch pneumonitis in chronic granulomatous disease: More than just a fungal infection.","authors":"Maarja Soomann, Seraina Prader, Tayfun Güngör, Jana Pachlopnik Schmid, Adilia Warris, Johannes Trück","doi":"10.1111/pai.70002","DOIUrl":"https://doi.org/10.1111/pai.70002","url":null,"abstract":"","PeriodicalId":19929,"journal":{"name":"Pediatric Allergy and Immunology","volume":"35 12","pages":"e70002"},"PeriodicalIF":4.3,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142791577","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reviewer Award 2024.","authors":"","doi":"10.1111/pai.70011","DOIUrl":"https://doi.org/10.1111/pai.70011","url":null,"abstract":"","PeriodicalId":19929,"journal":{"name":"Pediatric Allergy and Immunology","volume":"35 12","pages":"e70011"},"PeriodicalIF":4.3,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142807404","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Molecular allergen sensitization drives phenotypes of severe asthma in children: Evidence from a megacity cohort (SAMP).","authors":"Mélisande Bourgoin-Heck, Victoria Wolff-Goldnadel, Yannick Chantran, Sarah Saf, Tamazoust Guiddir, Flore Amat, Fanny Rancière, Isabelle Momas, Stéphanie Wanin, Thierry Rose, Philippe Saint-Pierre, Jocelyne Just","doi":"10.1111/pai.70014","DOIUrl":"10.1111/pai.70014","url":null,"abstract":"<p><strong>Background: </strong>Several major sensitization profiles have been described in children with asthma, but it remains unclear how these profiles relate to asthma phenotypes. The aim of this study was to determine allergenic sensitization profiles in a megacity cohort (SAMP).</p><p><strong>Methods: </strong>This was a cross-sectional analysis performed from 2011 to 2015 including preschool and school-age children with severe and moderate asthma from the SAMP cohort. We performed ALEX multiplex array and carried out cluster analysis.</p><p><strong>Results: </strong>Data from 367 children were analyzed: 224 of preschool age and 143 of school age, respectively 84 (38%) and 114 (80%) presented at least one allergic sensitization. At preschool age, three clusters were identified: Cluster 1, Few sensitizations to inhaled allergen molecular families and non-type 2 (T2) inflammation (n = 61); Cluster 2, Predominant sensitization to HDM molecular families (n = 16); Cluster 3, Severe asthma with multiple sensitizations to inhaled and food allergen molecular families (n = 7). At school age, five clusters were identified: Cluster 1, Few sensitizations to inhaled allergen molecular families and non-T2 inflammation (n = 43); Cluster 2, Predominant sensitization to HDM molecular families (n = 31); Cluster 3, Predominant sensitization to PR-10 protein family (n = 25); Cluster 4, Severe asthma with predominant sensitization to tropomyosin family (n = 11); Cluster 5, Severe asthma with multiple sensitizations to inhaled and food allergen molecular families (n = 4).</p><p><strong>Conclusion: </strong>These results underline the heterogeneity of sensitization profiles in severe allergic childhood asthma. The most severe asthma phenotypes were associated with multiple sensitizations to both inhaled and food allergen molecular families as expected, and to the tropomyosin molecular family, a novel finding.</p>","PeriodicalId":19929,"journal":{"name":"Pediatric Allergy and Immunology","volume":"35 12","pages":"e70014"},"PeriodicalIF":4.3,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11619752/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142786412","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}