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Measuring apixaban and rivaroxaban in the presence of heparin/LMWH using a heparin neutralisation procedure 测量阿哌沙班和利伐沙班在肝素/低分子肝素存在下使用肝素中和程序
IF 3.6 3区 医学
Pathology Pub Date : 2025-02-01 DOI: 10.1016/j.pathol.2024.12.105
Mandy Hubbard , Cale Burge , Geoff Kershaw
{"title":"Measuring apixaban and rivaroxaban in the presence of heparin/LMWH using a heparin neutralisation procedure","authors":"Mandy Hubbard , Cale Burge , Geoff Kershaw","doi":"10.1016/j.pathol.2024.12.105","DOIUrl":"10.1016/j.pathol.2024.12.105","url":null,"abstract":"","PeriodicalId":19915,"journal":{"name":"Pathology","volume":"57 ","pages":"Page S21"},"PeriodicalIF":3.6,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143092303","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
More than meets the eye: lid and conjunctival injuries in cases of non-sexual assault are frequently accompanied by non-fatal strangulation 不只是表面现象：在非性侵犯案件中，眼睑和结膜损伤通常伴随着非致命的勒死
IF 3.6 3区 医学
Pathology Pub Date : 2025-02-01 DOI: 10.1016/j.pathol.2024.12.055
Vanita Parekh
{"title":"More than meets the eye: lid and conjunctival injuries in cases of non-sexual assault are frequently accompanied by non-fatal strangulation","authors":"Vanita Parekh","doi":"10.1016/j.pathol.2024.12.055","DOIUrl":"10.1016/j.pathol.2024.12.055","url":null,"abstract":"","PeriodicalId":19915,"journal":{"name":"Pathology","volume":"57 ","pages":"Page S11"},"PeriodicalIF":3.6,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143092492","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evolution and development of FAMSACA FAMSACA的演变与发展
IF 3.6 3区 医学
Pathology Pub Date : 2025-02-01 DOI: 10.1016/j.pathol.2024.12.059
Kathy Kramer
{"title":"Evolution and development of FAMSACA","authors":"Kathy Kramer","doi":"10.1016/j.pathol.2024.12.059","DOIUrl":"10.1016/j.pathol.2024.12.059","url":null,"abstract":"","PeriodicalId":19915,"journal":{"name":"Pathology","volume":"57 ","pages":"Page S12"},"PeriodicalIF":3.6,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143092495","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Hyperandrogenism in pregnancy 妊娠期高雄激素症
IF 3.6 3区 医学
Pathology Pub Date : 2025-02-01 DOI: 10.1016/j.pathol.2024.12.030
Laura Buckton
{"title":"Hyperandrogenism in pregnancy","authors":"Laura Buckton","doi":"10.1016/j.pathol.2024.12.030","DOIUrl":"10.1016/j.pathol.2024.12.030","url":null,"abstract":"","PeriodicalId":19915,"journal":{"name":"Pathology","volume":"57 ","pages":"Pages S6-S7"},"PeriodicalIF":3.6,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143093021","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Elder maltreatment – physical 虐待老人——身体虐待
IF 3.6 3区 医学
Pathology Pub Date : 2025-02-01 DOI: 10.1016/j.pathol.2024.12.050
Kim Collins
{"title":"Elder maltreatment – physical","authors":"Kim Collins","doi":"10.1016/j.pathol.2024.12.050","DOIUrl":"10.1016/j.pathol.2024.12.050","url":null,"abstract":"","PeriodicalId":19915,"journal":{"name":"Pathology","volume":"57 ","pages":"Page S10"},"PeriodicalIF":3.6,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143093031","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Challenging small gland proliferations of the breast 具有挑战性的乳腺小腺体增生
IF 3.6 3区 医学
Pathology Pub Date : 2025-02-01 DOI: 10.1016/j.pathol.2024.12.019
Melinda Lerwill
{"title":"Challenging small gland proliferations of the breast","authors":"Melinda Lerwill","doi":"10.1016/j.pathol.2024.12.019","DOIUrl":"10.1016/j.pathol.2024.12.019","url":null,"abstract":"","PeriodicalId":19915,"journal":{"name":"Pathology","volume":"57 ","pages":"Page S4"},"PeriodicalIF":3.6,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143097776","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Blood in the eyes: PMCT of Terson syndrome. Implications for our understanding of retinal haemorrhage 眼睛出血：Terson综合征的PMCT。对我们理解视网膜出血的启示
IF 3.6 3区 医学
Pathology Pub Date : 2025-02-01 DOI: 10.1016/j.pathol.2024.12.078
Chris O'Donnell
{"title":"Blood in the eyes: PMCT of Terson syndrome. Implications for our understanding of retinal haemorrhage","authors":"Chris O'Donnell","doi":"10.1016/j.pathol.2024.12.078","DOIUrl":"10.1016/j.pathol.2024.12.078","url":null,"abstract":"","PeriodicalId":19915,"journal":{"name":"Pathology","volume":"57 ","pages":"Page S15"},"PeriodicalIF":3.6,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143092373","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Epidemiology and antimicrobial resistance rates for Shigella species in a resource-rich setting 在资源丰富的环境中志贺氏杆菌的流行病学和抗菌药耐药率。
IF 3.6 3区 医学
Pathology Pub Date : 2025-02-01 DOI: 10.1016/j.pathol.2024.07.004
Samuel Baumgart , Thuy Phan , Genevieve McKew
{"title":"Epidemiology and antimicrobial resistance rates for Shigella species in a resource-rich setting","authors":"Samuel Baumgart ,&nbsp;Thuy Phan ,&nbsp;Genevieve McKew","doi":"10.1016/j.pathol.2024.07.004","DOIUrl":"10.1016/j.pathol.2024.07.004","url":null,"abstract":"<div><div>Shigellosis is an acute, often dysenteric, diarrhoeal illness that is responsible for much morbidity and mortality worldwide. Increasing rates of multidrug-resistant (MDR) and extensively drug-resistant (XDR) ​<em>Shigella</em> species have been detected worldwide and a regular review of local epidemiological and resistance rates is necessary to help guide empirical antibiotic choice. This retrospective laboratory study of faecal isolates between 2013 and 2023 demonstrates increasing rates of resistance to third-generation cephalosporins, azithromycin and ciprofloxacin, alongside an overall increase in MDR and XDR isolates.</div></div>","PeriodicalId":19915,"journal":{"name":"Pathology","volume":"57 1","pages":"Pages 94-99"},"PeriodicalIF":3.6,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142505680","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparison of commonly used equations for sodium adjustment in hyperglycaemia 高血糖患者钠调整常用公式的比较。
IF 3.6 3区 医学
Pathology Pub Date : 2025-02-01 DOI: 10.1016/j.pathol.2024.07.009
Que Lam , Nilika Wijeratne
{"title":"Comparison of commonly used equations for sodium adjustment in hyperglycaemia","authors":"Que Lam ,&nbsp;Nilika Wijeratne","doi":"10.1016/j.pathol.2024.07.009","DOIUrl":"10.1016/j.pathol.2024.07.009","url":null,"abstract":"","PeriodicalId":19915,"journal":{"name":"Pathology","volume":"57 1","pages":"Pages 113-116"},"PeriodicalIF":3.6,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142546736","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Concentration of kidney markers and detection of exosomes in urine samples collected in cotton wool balls in preterm and term neonates 早产儿和足月新生儿用棉球收集的尿液样本中肾脏标志物的浓度和外泌体的检测。
IF 3.6 3区 医学
Pathology Pub Date : 2025-02-01 DOI: 10.1016/j.pathol.2024.07.006
Eveline Staub , Qinghua Cao , Xin-Ming Chen , Carol Pollock
{"title":"Concentration of kidney markers and detection of exosomes in urine samples collected in cotton wool balls in preterm and term neonates","authors":"Eveline Staub ,&nbsp;Qinghua Cao ,&nbsp;Xin-Ming Chen ,&nbsp;Carol Pollock","doi":"10.1016/j.pathol.2024.07.006","DOIUrl":"10.1016/j.pathol.2024.07.006","url":null,"abstract":"<div><div>Collecting urine samples in neonates by catheterisation or suprapubic puncture causes trauma, whereas self-adhesive collection bags can damage fragile skin. An alternative method is the collection of samples from urine-soaked cotton wool balls placed in diapers. The aim of this study was to compare the concentration of albumin, creatinine, neutrophil gelatinase-associated lipocalin (NGAL), and uromodulin between clean-catch urine and samples collected in cotton wool balls in neonates and assess the efficiency of exosome extraction. Standard clean-catch urine samples were assayed for albumin, creatinine, NGAL, and uromodulin using commercial enzyme-linked immunosorbent assay (ELISA) kits. Concentrations were compared to the same urine samples extracted immediately from soaked cotton wool balls (sample 2, S2) or the urine extracted from cotton wool balls placed in a diaper in a warm incubator for 2 h before extraction (sample 3, S3). Exosomes were extracted from all three samples of one patient for visualisation by electron microscopy. Twenty-six infants (17 males) of median gestational age at birth of 32+1 weeks had urine collected at a median age of 29 days at 37+6 weeks corrected age. Concentrations in S2 and S3 were within 10% of the concentration of standard samples in 46% and 35% of specimens for albumin, 69% and 58% for creatinine, 12% and 12% for NGAL, and 27% and 15% for uromodulin, respectively, without consistent positive or negative bias. Urine albumin/creatinine ratios (UACRs) were 4.3% less in S2 and 4.5% less in S3 than in standard samples. Exosomes were extracted and visualised from all three sample types. Neonatal urine samples extracted from cotton wool balls can be used to screen for relevant albuminuria ​but provide imprecise estimates of NGAL and uromodulin. The proof of exosome extraction from urine collection in cotton wool balls opens the potential to examine exosomal cargo.</div></div>","PeriodicalId":19915,"journal":{"name":"Pathology","volume":"57 1","pages":"Pages 81-86"},"PeriodicalIF":3.6,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142625676","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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