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Immunoprecipitation assays for the detection of specific extractable nuclear antigen ​autoantibodies: a role in the modern immunology laboratory? 用于检测特异性可提取核抗原自身抗体的免疫沉淀测定：在现代免疫学实验室中的作用？
IF 3.6 3区 医学
Pathology Pub Date : 2025-02-01 DOI: 10.1016/j.pathol.2024.08.008
Dimitra Beroukas , Peter J. Roberts-Thomson , Tom P. Gordon , Adrian Y.S. Lee
{"title":"Immunoprecipitation assays for the detection of specific extractable nuclear antigen ​autoantibodies: a role in the modern immunology laboratory?","authors":"Dimitra Beroukas , Peter J. Roberts-Thomson , Tom P. Gordon , Adrian Y.S. Lee","doi":"10.1016/j.pathol.2024.08.008","DOIUrl":"10.1016/j.pathol.2024.08.008","url":null,"abstract":"","PeriodicalId":19915,"journal":{"name":"Pathology","volume":"57 1","pages":"Pages 120-121"},"PeriodicalIF":3.6,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142625683","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
New challenges for HIV testing in the setting of long-acting cabotegravir pre-exposure prophylaxis 长效卡博替拉韦暴露前预防疗法对艾滋病毒检测的新挑战。
IF 3.6 3区 医学
Pathology Pub Date : 2025-02-01 DOI: 10.1016/j.pathol.2024.08.011
Eloise Williams , Doris Chibo , Jodie D'Costa , Suellen Nicholson , Kathy Jackson , Chuan K. Lim , Deborah A. Williamson
{"title":"New challenges for HIV testing in the setting of long-acting cabotegravir pre-exposure prophylaxis","authors":"Eloise Williams , Doris Chibo , Jodie D'Costa , Suellen Nicholson , Kathy Jackson , Chuan K. Lim , Deborah A. Williamson","doi":"10.1016/j.pathol.2024.08.011","DOIUrl":"10.1016/j.pathol.2024.08.011","url":null,"abstract":"","PeriodicalId":19915,"journal":{"name":"Pathology","volume":"57 1","pages":"Pages 105-107"},"PeriodicalIF":3.6,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142625769","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cribriform intraductal carcinoma of the prostate may be more aggressive than cribriform conventional/acinar prostatic adenocarcinoma 前列腺楔形导管内癌可能比楔形传统/尖锐前列腺腺癌更具侵袭性。
IF 3.6 3区 医学
Pathology Pub Date : 2025-02-01 DOI: 10.1016/j.pathol.2024.08.012
Ying Wang , Yuki Teramoto , Hiroshi Miyamoto
{"title":"Cribriform intraductal carcinoma of the prostate may be more aggressive than cribriform conventional/acinar prostatic adenocarcinoma","authors":"Ying Wang ,&nbsp;Yuki Teramoto ,&nbsp;Hiroshi Miyamoto","doi":"10.1016/j.pathol.2024.08.012","DOIUrl":"10.1016/j.pathol.2024.08.012","url":null,"abstract":"<div><div>It remains to be determined if the prognostic value of cribriform morphology (Crib) associated with intraductal carcinoma of the prostate (IDC) is equivalent to that in conventional/acinar prostatic adenocarcinoma (CPA). We herein assessed radical prostatectomy findings and long-term oncologic outcomes in 732 men with Grade Group 2–4 CPA without any Gleason pattern 5. Our cases were divided into four cohorts according to the absence or presence of Crib within CPA and/or IDC: Cohort-1, no Crib (<em>n</em>=347; 47.4%); Cohort-2, Crib only in CPA (<em>n</em>=203; 27.7%); Cohort-3, Crib only in IDC (<em>n</em>=17; 2.3%); and Cohort-4, Crib in both CPA and IDC (<em>n</em>=165; 22.5%). Compared with that in CPA only (Cohort-2), Crib in both CPA and IDC (Cohort-4) was significantly associated with adverse histopathological features, including higher tumour grade/stage and larger tumour volume. Univariate analysis revealed significantly higher risks of postoperative recurrence in patients with Crib in IDC only [Cohort-3; hazard ratio (HR) 2.450, <em>p</em>=0.022] or both CPA and IDC (Cohort-4; HR 2.835, <em>p</em>&lt;0.001) than in those with Crib in CPA only (Cohort-2), whereas the prognosis was analogous between Cohort-3 and Cohort-4 (<em>p</em>=0.913). In a multivariable analysis [Crib in CPA only (Cohort-2) as a reference], Crib in IDC only (Cohort-3; HR 3.821, <em>p</em>=0.002) or both CPA and IDC (Cohort-4; HR 1.905, <em>p</em>=0.004) showed significantly worse recurrence-free survival. Compared with Crib in CPA only, its presence in both CPA and IDC was thus found to be independently associated with a poorer prognosis, suggesting a potentially greater clinical impact of Crib in IDC than in CPA.</div></div>","PeriodicalId":19915,"journal":{"name":"Pathology","volume":"57 1","pages":"Pages 3-9"},"PeriodicalIF":3.6,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142731716","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Publishing and reviewing in the changing world of pathology journals 在不断变化的病理期刊中发表和评论
IF 3.6 3区 医学
Pathology Pub Date : 2025-02-01 DOI: 10.1016/j.pathol.2024.12.004
John R. Burnett , Wendy A. Cooper , Tristan Rutland , Diana Jones , Belinda Neill
{"title":"Publishing and reviewing in the changing world of pathology journals","authors":"John R. Burnett ,&nbsp;Wendy A. Cooper ,&nbsp;Tristan Rutland ,&nbsp;Diana Jones ,&nbsp;Belinda Neill","doi":"10.1016/j.pathol.2024.12.004","DOIUrl":"10.1016/j.pathol.2024.12.004","url":null,"abstract":"","PeriodicalId":19915,"journal":{"name":"Pathology","volume":"57 ","pages":"Page S1"},"PeriodicalIF":3.6,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143091822","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Problematic patterns of in-situ breast carcinoma 原位乳腺癌的可疑模式
IF 3.6 3区 医学
Pathology Pub Date : 2025-02-01 DOI: 10.1016/j.pathol.2024.12.015
Melinda Lerwill
{"title":"Problematic patterns of in-situ breast carcinoma","authors":"Melinda Lerwill","doi":"10.1016/j.pathol.2024.12.015","DOIUrl":"10.1016/j.pathol.2024.12.015","url":null,"abstract":"","PeriodicalId":19915,"journal":{"name":"Pathology","volume":"57 ","pages":"Page S4"},"PeriodicalIF":3.6,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143092112","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Measuring apixaban and rivaroxaban in the presence of heparin/LMWH using a heparin neutralisation procedure 测量阿哌沙班和利伐沙班在肝素/低分子肝素存在下使用肝素中和程序
IF 3.6 3区 医学
Pathology Pub Date : 2025-02-01 DOI: 10.1016/j.pathol.2024.12.105
Mandy Hubbard , Cale Burge , Geoff Kershaw
{"title":"Measuring apixaban and rivaroxaban in the presence of heparin/LMWH using a heparin neutralisation procedure","authors":"Mandy Hubbard ,&nbsp;Cale Burge ,&nbsp;Geoff Kershaw","doi":"10.1016/j.pathol.2024.12.105","DOIUrl":"10.1016/j.pathol.2024.12.105","url":null,"abstract":"","PeriodicalId":19915,"journal":{"name":"Pathology","volume":"57 ","pages":"Page S21"},"PeriodicalIF":3.6,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143092303","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
More than meets the eye: lid and conjunctival injuries in cases of non-sexual assault are frequently accompanied by non-fatal strangulation 不只是表面现象：在非性侵犯案件中，眼睑和结膜损伤通常伴随着非致命的勒死
IF 3.6 3区 医学
Pathology Pub Date : 2025-02-01 DOI: 10.1016/j.pathol.2024.12.055
Vanita Parekh
{"title":"More than meets the eye: lid and conjunctival injuries in cases of non-sexual assault are frequently accompanied by non-fatal strangulation","authors":"Vanita Parekh","doi":"10.1016/j.pathol.2024.12.055","DOIUrl":"10.1016/j.pathol.2024.12.055","url":null,"abstract":"","PeriodicalId":19915,"journal":{"name":"Pathology","volume":"57 ","pages":"Page S11"},"PeriodicalIF":3.6,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143092492","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evolution and development of FAMSACA FAMSACA的演变与发展
IF 3.6 3区 医学
Pathology Pub Date : 2025-02-01 DOI: 10.1016/j.pathol.2024.12.059
Kathy Kramer
{"title":"Evolution and development of FAMSACA","authors":"Kathy Kramer","doi":"10.1016/j.pathol.2024.12.059","DOIUrl":"10.1016/j.pathol.2024.12.059","url":null,"abstract":"","PeriodicalId":19915,"journal":{"name":"Pathology","volume":"57 ","pages":"Page S12"},"PeriodicalIF":3.6,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143092495","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Hyperandrogenism in pregnancy 妊娠期高雄激素症
IF 3.6 3区 医学
Pathology Pub Date : 2025-02-01 DOI: 10.1016/j.pathol.2024.12.030
Laura Buckton
{"title":"Hyperandrogenism in pregnancy","authors":"Laura Buckton","doi":"10.1016/j.pathol.2024.12.030","DOIUrl":"10.1016/j.pathol.2024.12.030","url":null,"abstract":"","PeriodicalId":19915,"journal":{"name":"Pathology","volume":"57 ","pages":"Pages S6-S7"},"PeriodicalIF":3.6,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143093021","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Elder maltreatment – physical 虐待老人——身体虐待
IF 3.6 3区 医学
Pathology Pub Date : 2025-02-01 DOI: 10.1016/j.pathol.2024.12.050
Kim Collins
{"title":"Elder maltreatment – physical","authors":"Kim Collins","doi":"10.1016/j.pathol.2024.12.050","DOIUrl":"10.1016/j.pathol.2024.12.050","url":null,"abstract":"","PeriodicalId":19915,"journal":{"name":"Pathology","volume":"57 ","pages":"Page S10"},"PeriodicalIF":3.6,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143093031","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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