G. Papava, I. Chitrekashvili, Marina Gurgenishvili, N. Gelashvili, K. Papava, K. Archvadze
{"title":"STUDY OF POLYCONDENSATION PROCESS TO RECEIVE BIODEGRADABLE POLYMERS","authors":"G. Papava, I. Chitrekashvili, Marina Gurgenishvili, N. Gelashvili, K. Papava, K. Archvadze","doi":"10.31435/rsglobal_ws/30062022/7835","DOIUrl":"https://doi.org/10.31435/rsglobal_ws/30062022/7835","url":null,"abstract":"Biodegradation of polymers of spatial structure is complicated at the impact of soil destructive microorganisms and biodegradation requires a long time. We have implemented a target-oriented synthesis of a polymer to receive linear structure polymers where labile peptide bonds are preserved. To implement target-oriented synthesis of a polymer and to determine optimal conditions for reaction mechanism we studied the process of kinetics and its regularities – reaction temperature, duration, components ratio, concentration, reaction speed constant, and activation energy. The Arrhenius factor and succession of the introduction of initial components to the reaction medium were computed, and catalyst nature and other properties were determined. A high effect of prolongation was achieved, when carbamide and formaldehyde molar ratio were 1:1. In this case linear structure polymer is formed where peptide -CH2 – NH – are preserved.","PeriodicalId":19855,"journal":{"name":"Pharmacy World & Science","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75258515","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
G. Papava, I. Chitrekashvili, E. Gavashelidze, Marina Gurgenishvili, N. Dokhturishvili, Shalva Papava
{"title":"SYNTHESIS OF AROMATIC POLYESTERS BASED ON NORBORNANE-CONTAINING DIOLS","authors":"G. Papava, I. Chitrekashvili, E. Gavashelidze, Marina Gurgenishvili, N. Dokhturishvili, Shalva Papava","doi":"10.31435/rsglobal_ws/30062022/7830","DOIUrl":"https://doi.org/10.31435/rsglobal_ws/30062022/7830","url":null,"abstract":"Aromatic polyesthers were synthesized on the base of policiclicbisphenols and dichloroanhydride of aromatic dicarboxylic acid by the method of equilibrium polycondensation in solvent. The obtained polymers are characterized by high heat-and thermal stability, are well soluble in chlorinated hydrocarbons and they form transparent films from solutions which are characterized by good mechanical and dielectric properties.","PeriodicalId":19855,"journal":{"name":"Pharmacy World & Science","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-06-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89239832","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"THE IMPACT OF DIESEL BUS EMISSIONS ON AIR POLLUTION IN ULAANBAATAR AND ATTEMPT TO REDUCE IT","authors":"Tsetsegmaa Agvaantseren, Bayarsuren Badarch, Altantsetseg Tseveg","doi":"10.31435/rsglobal_ws/30062022/7829","DOIUrl":"https://doi.org/10.31435/rsglobal_ws/30062022/7829","url":null,"abstract":"The advantages of diesel engines have led it to become the only solution for heavy-duty vehicles (HDV), including city buses. Exhaust gas from diesel engines (EG) is a common environmental pollutant and carcinogenic to human health. The paper presents the results of measuring the emissions of city buses running on high sulfur fuel with and without diesel particulate filter (DPF). The study was conducted in real traffic conditions along the regular route of the city of Ulaanbaatar. The measurements were carried out using the HORIBA PEMS (Portable Emissions Measurement System) and the gravimetric method. The measured data was used to determine the actual emission levels from city buses. The actual particulate matter (PM) emissions from city buses were determined during the warm and cold seasons on a daily basis. It is found that a bus with average daily mileage of 242 km emits average of 166.155 g of PM into the atmosphere per day. This fluctuates depending on the season - 141.3 g in summer and 175.8 g in winter. The actual PM emissions of a city bus is 0.6866 g/km. The NOx concentration in the exhaust gases is 1410.94 ppm on average. As a result of 6 months of measurements, a total of 346.651 kg of soot was collected from 24 buses. Innovation: Actual on-road emissions from Ulaanbaatar buses and a cassette-type DPF system with “active” outside the bus regeneration, that can reduce conventional diesel engine PM emissions by up to 90% regardless of the sulfur content of the fuels.","PeriodicalId":19855,"journal":{"name":"Pharmacy World & Science","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-06-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88752250","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"RESEARCH OF DESIGNS OF THE AXIAL DRUM EQUIPMENT OF STONE MATERIAL SORTING","authors":"Gunsen Ganbaatar, Yadam Renchinvanjil","doi":"10.31435/rsglobal_ws/30062022/7821","DOIUrl":"https://doi.org/10.31435/rsglobal_ws/30062022/7821","url":null,"abstract":"There are studies showing that 10% of the total energy generated in the world is spent on crushing and sifting and sorting processes in mining sectors. 52.7% of the total mining industries extract metal ores, and 36.3% of them extract coal. It can be seen that there is a need for sorting the materials with particles in these sectors. According to the needs, the energy expenditure is high and the devices and equipment used still maintain their traditional designs and makes. The process of sorting out the materials with particles is sifted by the flat-surfaced, trommel-shaped, and cylindrical mesh surfaces positioned on the vertical axis. The above methods are still in use, and this becomes the basis of mechanical sifting methods. Therefore, the researchers continue to work on perfecting the above methods. The goal of this research work is to survey and determine the possibility that changes in the designs of sifting equipment with the trommels can improve the influences that are created during the sifting process, the efficiency of sifting, and the productivity of the device or equipment. In this research work, with the purpose to improve the parameters of sifting materials with particles, we will change the design of the cylindrical trommel of the cross trommel sieve, which is often used in the sifting process to the axle to its axis, and in order to confirm the results of the experiment by determining the CAD analysis of axle trommel and the movement of one particle inside of it using the ADAMS software, the experiment on the real equipment shall be rationalized by putting into the mathematic modeling, develop the physical modeling using the “EDEM solution” software and process the results.","PeriodicalId":19855,"journal":{"name":"Pharmacy World & Science","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81788857","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Natela Khetsuriani, Madlena Chkhaidze, Georgi AbramiShvili, Jumbler Iosebidze
{"title":"PRODUCTION AND STUDY OF BIO GAZOLINES","authors":"Natela Khetsuriani, Madlena Chkhaidze, Georgi AbramiShvili, Jumbler Iosebidze","doi":"10.31435/rsglobal_ws/30062022/7820","DOIUrl":"https://doi.org/10.31435/rsglobal_ws/30062022/7820","url":null,"abstract":"Combustible ethanol was obtained from agricultural waste. Test samplesE0 (petrolgazoline) and E5, E10 and E20 (epanpl/gazoline blend) were prepared and their physical, chemical and technical characteristics were studied. The effect of bioethanol on the ecological compatibility of the automobile engine has been studied. The objects of research were Regular, Premium and Super of Petrol gasoline Samples, as well as a of 10%, 20% and 30%. bioethanol/gazoline blends. The study of the ecological properties of the test additive was carried out at the stand of automobile engines SAK-670 (Germany), on which the engine of a BMW-316 car with coupling sleeve and a transmission assembly is installed. The stand is equipped with brakes and torque sensors, as well as with crankshaft speed and fuel consumption measuring instruments. The test mixtures during an idle running of engine cause a decrease in the CO content in the exhaust gases by 10-16%, and this taking into account their low cost, indicate the prospect of expanding the use of fuel ethanol.","PeriodicalId":19855,"journal":{"name":"Pharmacy World & Science","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-05-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78535896","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Kovalchuk A. V., Zinich O. V., Prybyla O. V., Kushnareva N. M., Kovalchuk V. M., Shyshkan-Shyshova K. O.
{"title":"OSTEOCALCIN ROLE IN THE REGULATION OF INSULIN SECRETION AND OSTEOTROPIC EFFECTS OF DIFFERENT CLASSES OF ANTI-DIABETIC DRUGS (LITERATURE REVIEW AND OWN RESEARCH)","authors":"Kovalchuk A. V., Zinich O. V., Prybyla O. V., Kushnareva N. M., Kovalchuk V. M., Shyshkan-Shyshova K. O.","doi":"10.31435/rsglobal_ws/30042022/7803","DOIUrl":"https://doi.org/10.31435/rsglobal_ws/30042022/7803","url":null,"abstract":"Background. Current data suggest that bone tissue produces hormonally active factors - modulators of metabolic processes throughout the body. The most significant osteoproteins is osteocalcin, the non-collagen structural protein of the bone matrix, which is synthesized by osteoblasts and enters the bloodstream during the resorption of bone tissue. Osteocalcin is involved in the regulation of energy balance, insulin secretion, peripheric insulin sensitivity, and adipocyte’s function, while being an important marker of bone remodeling. The aim of this study was to investigate the relationship between osteocalcin levels and metabolic parameters in 97 patients with type 2 diabetes over 50 years of age, in the course of pharmacotherapy using different classes of antidiabetic drugs, namely human insulin, glucagon-like peptide-1 agonists (aGLP), and sodium-glucose co-transporter 2 (SGLT2) inhibitors, depending on presence of obesity. Results. There was found the highest serum osteocalcin level in patients without obese who received a metabolically active therapy with insulin or aGLP-1, comparing to nonobese subjects of SGLT2 inhibitors therapy group. The lowest level of HbA1c and triglycerides observed in non-obese patients on the background of taking aGLP-1. Conclusion. It can be assumed that the factor determining the hypoglycemic efficacy of investigated drugs may be the pathogenesis of type 2 diabetes which depends on the degree of obesity, while the type of antidiabetic therapy has a corrective effect, probably mediated by changes in body weight and fat distribution.","PeriodicalId":19855,"journal":{"name":"Pharmacy World & Science","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85619100","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"DIESEL ENGINE FUEL AND OIL CONTAMINATION IN THE AGRICULTURE SECTOR OF MONGOLIA","authors":"Erdenesaikhan Oyunsurtal, Ulziibaatar Tserendorj","doi":"10.31435/rsglobal_ws/30042022/7806","DOIUrl":"https://doi.org/10.31435/rsglobal_ws/30042022/7806","url":null,"abstract":"The study was conducted to determine the amount of contamination such as soot and silicon iron of engine oil and fuel contamination of tractors of Mongolia's agricultural sector. According this research, tractors were randomly selected for field testing during spring’s sowing and summer and autumn harrowing time, and fuel and oil samples were taken from them with a special vacuum suction according relevant instructions and the amount of contamination was determined in accredited laboratory of Tecenomics Mongolia LLC. According to the test results, fuel contamination increases exponentially and oil contamination increases polynomial, those results depending on the type of agricultural works, and period of the work in the field of the tractors.","PeriodicalId":19855,"journal":{"name":"Pharmacy World & Science","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-04-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78845646","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"CRANIOTOMY WITH A HERMETIC CLOSURE OF THE CRANIAL CAVITY","authors":"Napoleon Meskhia","doi":"10.31435/rsglobal_ws/30042022/7805","DOIUrl":"https://doi.org/10.31435/rsglobal_ws/30042022/7805","url":null,"abstract":"Surgical intervention on the contents of the cranial cavity is universally carried out by applying several burr holes, which remain uncovered and serve as a site for the development of a number of postoperative complications. The lack of hemeticity of the skull in some cases require repeated intervention. The purpose of the proposal is to create a trepanation method that excludes the formation of burr holes and promotes hermetic closure of the cranial cavity, excluding the possibility of postoperative complications.The goal is achieved by sawing out conical holes in the skull with the simultaneous formation of small bone flaps in the form of a truncated cone. A large bone fragment of a derivative form is cut out with the proposed tool or in the usual way with a Gigli or Olivecrona saw. In the absence of contraindications, a large bone flap is placed in place, and small bone fragments are combined with the place of their sawing, thereby restoring the integrity of the skull, which is closed at the end of the intervention.The hermetic craniotomy method eliminates the possibility of developing postoperative complications inherent in craniotomy methods, carried out by applying burr holes.The method of craniotomy, which provides for hermetic closure of the cranial cavity, among other things, returns the brain to its natural state, protected from all kinds of external influences, including postoperative complications","PeriodicalId":19855,"journal":{"name":"Pharmacy World & Science","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89242173","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"MALABSORPTION AND LACTOSE INTOLERANCE: PATHOPHYSIOLOGY, DIAGNOSIS AND TREATMENT OF PATHOGENESIS","authors":"Olena Sharikadze","doi":"10.31435/rsglobal_ws/30042022/7804","DOIUrl":"https://doi.org/10.31435/rsglobal_ws/30042022/7804","url":null,"abstract":"The problem of lactose metabolism remains relevant from the standpoint of various areas of medical research. Clinicians, anthropologists, physiologists and geneticists are engaged in the study of lactose digestion devices and various types of disorders associated with it, including lactose intolerance.Determination of such mechanisms allows us to understand not only the nutritional causes of the development of functional intestinal symptoms, but also the evolution of man and nutrition, culture and lifestyle. Symptoms of lactose intolerance are abdominal pain, flatulence, nausea, bloating, and diarrhea after drinking milk or dairy products. These symptoms may be caused by malabsorption of lactose, which is the result of low levels of lactase in the small intestine. Symptoms also occur after consumption of lactose or lactose products, with no apparent effect on the human microbiota and overall health. Therefore, of particular concern are the strict dairy-free diets commonly prescribed for patients with such complaints.This article discusses modern recommendations for the diagnosis and treatment of lactose malabsorption and lactose intolerance, which largely comply with European recommendations.","PeriodicalId":19855,"journal":{"name":"Pharmacy World & Science","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-04-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83172728","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"THE INTENSIVE TECHNOLOGY OF GROWING STRAWBERRIES UNDER COVER","authors":"Leila Ebralidze, Shota Lominadze","doi":"10.31435/rsglobal_ws/28022022/7775","DOIUrl":"https://doi.org/10.31435/rsglobal_ws/28022022/7775","url":null,"abstract":"The intensive technology of growing strawberries under cover, the production of maximum yield in the greenhouses, the structure of strawberry beds, the preparation, composting and sterilization of the substrate, raising the seedlings of strawberry, comparative economic evaluation they are KEYWORDS reviewed in the article.","PeriodicalId":19855,"journal":{"name":"Pharmacy World & Science","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76651209","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}