{"title":"Comments on \"Lumbar Medial Branch Cryoneurolysis Improves Pain and Function Versus Radiofrequency Ablation for Chronic Low Back Pain: 12-Month Randomized Pilot Study\".","authors":"Shahin Azizov","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":19841,"journal":{"name":"Pain physician","volume":"29 2","pages":"E129"},"PeriodicalIF":2.5,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147777703","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Junchao Zhang, Lei Tong, Rui Guo, Xiafei Zhou, Yun Li, Yunzhong Zhan, Yi Mao
{"title":"Effect of Paravertebral Blocks Combined with Percutaneous Kyphoplasty on Thoracic Vertebral Fractures Complicated with Costal Pain.","authors":"Junchao Zhang, Lei Tong, Rui Guo, Xiafei Zhou, Yun Li, Yunzhong Zhan, Yi Mao","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>Vertebral augmentation surgery has shown good results for treating osteoporotic vertebral compression fractures, but its effect on relieving costal pain is not satisfactory.</p><p><strong>Objective: </strong>To study the clinical efficacy of combining thoracic paravertebral nerve blocks (TPVNBs) with percutaneous kyphoplasty (PKP) in the treatment of thoracic vertebral fractures with costal pain, providing a reference for clinical diagnosis and management.</p><p><strong>Study design: </strong>A retrospective study.</p><p><strong>Setting: </strong>A single medical center in China.</p><p><strong>Methods: </strong>This was a retrospective cohort study. Patients who underwent PKP for thoracic fractures with costal pain at Quzhou People's Hospital from March 1, 2021, to March 1, 2023, were included. They were divided into a paravertebral block group (PVB group) and a control group. Pain intensity was measured using the Visual Analog Scale (VAS) before surgery and at multiple postoperative intervals. Physical function was evaluated using the Patient-Reported Outcomes Measurement Information System Physical Function (PROMIS PF) tool, and treatment satisfaction was recorded using the Modified Macnab Criteria.</p><p><strong>Results: </strong>A total of 73 patients met the inclusion criteria, with 35 in the PVB group and 38 in the control group. Preoperative VAS scores for back pain and costal pain were similar between the 2 groups. Postoperatively, both groups experienced significant pain reduction, but the PVB group had better costal pain relief in the early follow-up period (within the first 3 months) and greater early functional recovery. At 12 months, the satisfaction rate was higher in the PVB group (94.3%) than in the control group (76.3%).</p><p><strong>Limitations: </strong>The study's retrospective design, small sample size, short follow-up period, and incomplete understanding of pathogenesis limit the generalizability and long-term assessment of its findings.</p><p><strong>Conclusion: </strong>A combination of PKP and PVB can significantly improve the pain relief rate and the quality of life in the early postoperative period of patients with thoracic vertebral fractures and costal pain.</p>","PeriodicalId":19841,"journal":{"name":"Pain physician","volume":"29 2","pages":"E81-E86"},"PeriodicalIF":2.5,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147778092","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Vitamin D Supplementation in the Management of Painful Diabetic Peripheral Neuropathy: A Narrative Review.","authors":"Seoyon Yang, Dong Soon Jang, Min Cheol Chang","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>Painful diabetic peripheral neuropathy (DPN), a debilitating complication of diabetes mellitus (DM), significantly reduces quality of life. Vitamin D deficiency is common in patients with DM and has been associated with both the presence and severity of DPN.</p><p><strong>Objectives: </strong>This systematic review aims to investigate whether vitamin D supplementation improves neuropathic symptoms in patients with painful DPN.</p><p><strong>Study design: </strong>A narrative review.</p><p><strong>Methods: </strong>A systematic literature search was conducted in MEDLINE (PubMed), the Cochrane Library, Embase, Scopus, and the Web of Science for English-language articles published through August 7, 2025. Studies were included if they evaluated the effects of vitamin D supplementation in patients with painful DPN.</p><p><strong>Results: </strong>Overall, 50 articles were identified through the database search. After screening titles and abstracts, 39 articles were excluded for not meeting the inclusion criteria. The remaining 11 articles were assessed for full-text eligibility. Finally, 7 studies were included in this review. Most of those studies reported improvements in pain scores, quality of life, and serum 25(OH)D levels following vitamin D supplementation. The findings suggest that vitamin D alleviates neuropathic pain by modulating inflammatory responses, promoting nerve regeneration, and enhancing the expression of neurotrophic factors.</p><p><strong>Limitations: </strong>Further randomized controlled trials are needed to confirm the therapeutic efficacy of vitamin D supplementation and to establish the optimal dosage, frequency, and treatment duration associated with it.</p><p><strong>Conclusion: </strong>The findings support the consideration of vitamin D supplementation as a potential adjunctive strategy for managing painful DPN.</p>","PeriodicalId":19841,"journal":{"name":"Pain physician","volume":"29 2","pages":"E67-E74"},"PeriodicalIF":2.5,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147778120","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Comment on \"Comparison of Different Spinal Level Approaches in Splanchnic Sympathetic Neurolysis for Intractable Upper Abdominal Cancer Pain\".","authors":"Ling Ye, Peiying You","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":19841,"journal":{"name":"Pain physician","volume":"29 2","pages":"E120-E121"},"PeriodicalIF":2.5,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147777721","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Pain after Heart Surgery: The Tip of the Iceberg.","authors":"Mesut Engin, Filiz Ata, Umran Karaca, Senol Yavuz","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":19841,"journal":{"name":"Pain physician","volume":"29 2","pages":"E126"},"PeriodicalIF":2.5,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147778093","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Tugce Gezer Karabacak, Savas Sencan, Serdar Kokar, Osman Hakan Gunduz
{"title":"The Effect of Different Spinal Levels on Splanchnic Sympathetic Neurolysis Remains Controversial.","authors":"Tugce Gezer Karabacak, Savas Sencan, Serdar Kokar, Osman Hakan Gunduz","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":19841,"journal":{"name":"Pain physician","volume":"29 2","pages":"E119"},"PeriodicalIF":2.5,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147778143","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Comment on \"Is Fibromyalgia a Nociplastic or a Mixed-pain Condition? International, Multidisciplinary Recommendations for Pain Phenotyping in Fibromyalgia Syndrome\".","authors":"Antonio Alcantara Montero","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":19841,"journal":{"name":"Pain physician","volume":"29 2","pages":"E122-E123"},"PeriodicalIF":2.5,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147777669","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Maram A T M Khaled, Jessica D Spence, Charles S Brudney, Emilie P Belley-Cote
{"title":"Comments on \"Significant, Meaningful, or Dangerous? Rethinking How We Interpret Evidence\".","authors":"Maram A T M Khaled, Jessica D Spence, Charles S Brudney, Emilie P Belley-Cote","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":19841,"journal":{"name":"Pain physician","volume":"29 2","pages":"E134-E135"},"PeriodicalIF":2.5,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147777750","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}