Pediatric Cardiology最新文献_第8页

Predicting Cardiac Magnetic Resonance-Derived Ejection Fraction from Echocardiogram Via Deep Learning Approach in Tetralogy of Fallot. 基于深度学习的法洛四联症超声心动图预测心脏磁共振射血分数。

IF 1.5 4区医学

Pediatric Cardiology Pub Date : 2025-03-04 DOI: 10.1007/s00246-025-03802-y

Arnav Adhikari, G Vick Wesley, Minh B Nguyen, Tam T Doan, Mounica Y Rao, Anitha Parthiban, Lance Patterson, Kashika Adhikari, David Ouyang, Jeffery S Heinle, Lalita Wadhwa

{"title":"Predicting Cardiac Magnetic Resonance-Derived Ejection Fraction from Echocardiogram Via Deep Learning Approach in Tetralogy of Fallot.","authors":"Arnav Adhikari, G Vick Wesley, Minh B Nguyen, Tam T Doan, Mounica Y Rao, Anitha Parthiban, Lance Patterson, Kashika Adhikari, David Ouyang, Jeffery S Heinle, Lalita Wadhwa","doi":"10.1007/s00246-025-03802-y","DOIUrl":"https://doi.org/10.1007/s00246-025-03802-y","url":null,"abstract":"Systolic function assessment is essential in children with congenital heart disease. Traditional methods of echocardiographic left ventricular ejection fraction (LVEF) estimation might overestimate systolic function compared to the gold standard of cardiac magnetic resonance imaging (CMR), especially in Tetralogy of Fallot (TOF). Deep learning technologies such as EchoNet-Dynamic offer more consistent cardiac evaluations and can potentially accurately predict LVEF using echocardiographic videos. The EchoNet-Dynamic/EchoNet-Peds models predict LVEF using echocardiograms with expert-measured LVEF as the ground truth. Using a transfer learning approach, we fine-tuned this model to predict LVEF with CMR-derived LVEF as ground truth and TOF echocardiograms as input images. For echocardiograms in the PSAX view, the model predicted CMR LVEF with an R2 of 0.79 and an MAE of 4.41. For the A4C view, the model predicted CMR LVEF with an R2 of 0.53 and an MAE of 6.4. Plotted ROC curves indicate that both tuned models differentiated well between normal and reduced LVEF. This study shows the potential of Convolutional Neural Network (CNN) models in transforming the field of cardiac imaging interpretation via a hybrid approach using the CMR labels and echocardiogram videos offering advancements over conventional methods.","PeriodicalId":19814,"journal":{"name":"Pediatric Cardiology","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2025-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143557385","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Contraception Use in Adolescents and Young Adults with Congenital Heart Disease. 患有先天性心脏病的青少年和青壮年避孕措施的使用

IF 1.5 4区医学

Pediatric Cardiology Pub Date : 2025-03-03 DOI: 10.1007/s00246-025-03791-y

Jaclyn Giafaglione, May Ling Mah, Lydia K Wright

{"title":"Contraception Use in Adolescents and Young Adults with Congenital Heart Disease.","authors":"Jaclyn Giafaglione, May Ling Mah, Lydia K Wright","doi":"10.1007/s00246-025-03791-y","DOIUrl":"https://doi.org/10.1007/s00246-025-03791-y","url":null,"abstract":"Women with congenital heart disease (CHD) are at elevated risk for morbidity and mortality during childbirth. Pediatric cardiologists are in a unique position to provide reproductive counseling to their patients with CHD. We evaluated contraception use in adolescents and young adults with CHD seen in a pediatric cardiology practice. Utilizing retrospective chart review, we evaluated all encounters for female patients aged 14 - 21 years with CHD between January 2017 and June 2023 at a tertiary care center. Female patients without CHD seen over the same period were included as a comparator group. Logistic regression was used to evaluate predictors of contraception use. There were 12, 368 visits included in our study. Of the 9924 visits in patients without CHD, 23% were on contraception, and of the 2444 visits in patients with CHD, 22% were on contraception. There was an increase in contraception use over time. Controlling for age at visit, later visit year was associated with contraception use (OR 1.09 [95% CI 1.04-10.9] per year). CHD was associated with lower likelihood of contraception use [OR 0.79 [95% CI 0.70 - 0.88]). Those with single ventricle (SV) CHD and complex CHD used long-acting reversible contraception more often (54% and 46% respectively) compared to those with simple or moderate CHD (17% and 16% respectively) or no CHD (18%). Patients with CHD are receiving contraception at a lower rate than those without CHD. Given the risks that women with CHD face with pregnancy, there should be a dedicated effort to increase the percentage of women with CHD on contraception.","PeriodicalId":19814,"journal":{"name":"Pediatric Cardiology","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2025-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143542761","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Rebuttal to "Comment on: Early Post-operative ECG Changes as a Predictor of Post-pericardiotomy Syndrome Following Atrial Septal Defect Repair". 对 "关于：术后早期心电图变化作为心房室间隔缺损修复术后心包切开综合征的预测指标 "的评论。

IF 1.5 4区医学

Pediatric Cardiology Pub Date : 2025-03-01 Epub Date: 2024-11-13 DOI: 10.1007/s00246-024-03711-6

William Hanna, Kristen Hyberg, Iqbal El-Assad

引用次数: 0

Letter to the Editor: "Risk Factors and Outcomes Associated with Gaps in Care in Children with Congenital Heart Disease". 致编辑的信：“与先天性心脏病患儿护理缺口相关的危险因素和结果”。

IF 1.5 4区医学

Pediatric Cardiology Pub Date : 2025-03-01 Epub Date: 2024-12-24 DOI: 10.1007/s00246-024-03758-5

Disha Bai, Sonia Kumari, Kanwal Majeed

引用次数: 0

An Infant with High-Output Heart Failure and Pulmonary Hypertension Resulting from a Giant Cutaneous Hemangioma. 巨大皮肤血管瘤导致婴儿高输出性心力衰竭和肺动脉高压。

IF 1.5 4区医学

Pediatric Cardiology Pub Date : 2025-03-01 Epub Date: 2024-06-01 DOI: 10.1007/s00246-024-03528-3

Andrew A Lawson, Wayne H Franklin, Nicolas F M Porta, Alan Nugent, Amanda Hauck

引用次数: 0

NT-proBNP for Predicting All-Cause Death and Heart Transplant in Children and Adults with Heart Failure. NT-proBNP 用于预测儿童和成人心力衰竭患者的全因死亡和心脏移植。

IF 1.5 4区医学

Pediatric Cardiology Pub Date : 2025-03-01 Epub Date: 2024-05-09 DOI: 10.1007/s00246-024-03489-7

Walter Schmitt, Christian Diedrich, Taye H Hamza, Michaela Meyer, Thomas Eissing, Stefanie Breitenstein, Joseph W Rossano, Steven E Lipshultz

{"title":"NT-proBNP for Predicting All-Cause Death and Heart Transplant in Children and Adults with Heart Failure.","authors":"Walter Schmitt, Christian Diedrich, Taye H Hamza, Michaela Meyer, Thomas Eissing, Stefanie Breitenstein, Joseph W Rossano, Steven E Lipshultz","doi":"10.1007/s00246-024-03489-7","DOIUrl":"10.1007/s00246-024-03489-7","url":null,"abstract":"Plasma N-terminal prohormone B-type natriuretic peptide (NT-proBNP) concentration is a heart failure (HF) biomarker in adults and children. Its prognostic value for HF-related events has been established only in adults. Therefore, we aimed to test the hypothesis that plasma NT-proBNP concentrations predicted the risk of heart transplantation or death in children with HF. We studied the medical records of 109 children with HF enrolled in the IBM Watson Explorys database and from 150 children enrolled in the Pediatric Cardiomyopathy Registry (PCMR). Nonlinear regression was used to assess the relationship between plasma NT-proBNP concentrations and the risk of events in the two cohorts. All children in the PCMR cohort had dilated cardiomyopathy. The Explorys cohort also included children with congenital cardiovascular malformations. Median plasma NT-proBNP concentrations were 1250 pg/mL and 184 pg/mL in the Explorys and PCMR cohorts, respectively. The percentage of deaths/heart transplantations was 7%/22%, over 2 years in the Explorys cohort and 3%/16% over 5 years in the PCMR cohort. Mean estimates of plasma NT-proBNP concentration indicative of half-maximum relative risk for events (EC50 values) at 2 and 5 years were 3730 pg/mL and 4199 pg/mL, respectively, values both close to the mean of 3880 pg/mL established for adults with HF. The plasma NT-proBNP concentration is suitable for estimating relative risk of mortality and heart transplantation in children with HF, independent of etiology and shows similar relations to clinical outcomes as in adults, indicating its likely value as a surrogate marker both for adult and pediatric HF.ClinicalTrials.gov Identifiers: NCT00005391 (May 26, 2000), NCT01873976 (June 10, 2013).","PeriodicalId":19814,"journal":{"name":"Pediatric Cardiology","volume":" ","pages":"694-703"},"PeriodicalIF":1.5,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11842395/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140898715","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Rebuttal to Letter to the Editor: Congenital Heart Defects in Patients with Anorectal Malformations: A Retrospective Cohort Study of 281 Patients. 对致编辑信的反驳：肛肠畸形患者的先天性心脏缺陷：一项281例患者的回顾性队列研究。

IF 1.5 4区医学

Pediatric Cardiology Pub Date : 2025-03-01 Epub Date: 2025-01-28 DOI: 10.1007/s00246-024-03739-8

Cunera M C de Beaufort, Tara M Mackay, Markus F Stevens, Jorinde A W Polderman, Justin R de Jong, Annelies E van der Hulst, Bart Straver, Ramon R Gorter

引用次数: 0

Feasibility of Electric Impedance Tomography in the Assessment of Lung Perfusion and Ventilation in Congenital Pulmonary Vein Stenosis. 电阻抗断层扫描评价先天性肺静脉狭窄患者肺灌注和通气的可行性。

IF 1.5 4区医学

Pediatric Cardiology Pub Date : 2025-03-01 DOI: 10.1007/s00246-025-03816-6

Jenny E Zablah, Catalina Vargas-Acevedo, Nilton da BarbosaRosa, Omid Rajabi Shishvan, Gary Saulnier, David Isaacson, Gareth J Morgan, Jennifer L Mueller

{"title":"Feasibility of Electric Impedance Tomography in the Assessment of Lung Perfusion and Ventilation in Congenital Pulmonary Vein Stenosis.","authors":"Jenny E Zablah, Catalina Vargas-Acevedo, Nilton da BarbosaRosa, Omid Rajabi Shishvan, Gary Saulnier, David Isaacson, Gareth J Morgan, Jennifer L Mueller","doi":"10.1007/s00246-025-03816-6","DOIUrl":"https://doi.org/10.1007/s00246-025-03816-6","url":null,"abstract":"Pulmonary vein stenosis (PVS) is a complex disease that requires repeated percutaneous interventions. Electrical impedance tomography (EIT) is a functional imaging technique that provides real-time images of pulmonary perfusion and ventilation. We aimed to determine the feasibility of EIT to evaluate ventilation/perfusion in PVS before and after catheter-based interventions. EIT was conducted in patients with PVS using the ACT5 EIT system. Lung regions were segmented from the perfusion images, and time-dependent blood volume curves were computed voxel-wise and by lung region. The distribution of pulmonary blood flow (PBF) was computed from EIT images and compared pre and post intervention. Finally, a blinded interventional cardiologist reviewed the results to evaluate three findings: (1) side and extent of PVS, (2) perfusion, and (3) ventilation. During the study period, twelve patients were included. Of these, seven were female (58.3%) with a median age of 3.5 years. Six patients had history of prematurity, and four had history of previous surgical PVS intervention. Three patients (25%) had an episode of pulmonary hemorrhage during the current intervention. In general, ventilation/perfusion data were successfully obtained in all cases. EIT correctly depicted all 12 cases of PVS correlating with angiography performed on the same day. EIT is a non-invasive, radiation-free technique that estimates lung perfusion/ventilation and percent distribution of PBF. The subject-based evaluation of EIT correlates to the severity and sidedness of the veins involved. This technology has the potential of providing perfusion/ventilation information in-PVS patients without the need of contrast or radiation.","PeriodicalId":19814,"journal":{"name":"Pediatric Cardiology","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143537755","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Use of a Postoperative Care Management Pathway Reduces the Incidence of Chylothorax Post-Fontan Palliation. 术后护理管理路径的使用降低了方坦姑息术后乳糜胸的发生率。

IF 1.5 4区医学

Pediatric Cardiology Pub Date : 2025-03-01 Epub Date: 2024-06-11 DOI: 10.1007/s00246-024-03494-w

Alanna Ash, Lindsay Ryerson, Vijay Anand, Jennifer Conway, Rae Foshaug, George Slim, Iman Naimi, Luke Eckersley

{"title":"Use of a Postoperative Care Management Pathway Reduces the Incidence of Chylothorax Post-Fontan Palliation.","authors":"Alanna Ash, Lindsay Ryerson, Vijay Anand, Jennifer Conway, Rae Foshaug, George Slim, Iman Naimi, Luke Eckersley","doi":"10.1007/s00246-024-03494-w","DOIUrl":"10.1007/s00246-024-03494-w","url":null,"abstract":"Pleural effusions and chylothorax are challenging morbidities post-Fontan palliation. We sought to evaluate the efficacy of our Fontan Care Pathway (FCP) in reducing the incidence of post-operative chylothorax and Time to Chest Tube Removal (TTCTR), and to determine risk factors associated with longer TTCTR. Between 2016 and 2022 our institutional approach to post-Fontan care fell into three categories: Group 1 (n = 36): no standardized approach; Group 2 (n = 30): a prophylactic chylothorax diet (fat content < 5%); Group 3 (n = 57): the FCP (a chylothorax diet, fluid restriction, supplemental O2 and aggressive diuresis). The incidence of chylothorax and TTCTR was compared between groups. Predictors of TTCTR were analyzed using linear regression modelling, adjusting for covariates. Chylothorax rate decreased in Group 3 compared to Groups 1 and 2 (9% vs. 28% and 33% respectively, p = 0.011), without alteration in TTCTR. Univariate factors associated with median TTCTR included chylothorax (+ 13.7 days, p = 0.001), additional procedures at time of Fontan (+ 2.4 days per procedure p = 0.017), Fontan revision or takedown (+ 11.7 days, p = 0.018) and minor/major complications (+ 5.1, p = 0.01 and + 15.8, p < 0.001, respectively). On multivariable analysis, chylothorax (+ 6.5 days, p = 0.005) and major complications (+ 15.8 days, p = 0.001) were associated with increased TTCTR. When chylothorax was excluded from multivariable analysis, the FCP showed a significant decrease in TTCTR (- 3.3 days, p = 0.034). A bundled therapy approach was associated with reduced laboratory confirmed chylothorax post-Fontan, whereas diet change alone was not. Additional studies in this area, with larger sample sizes are warranted.","PeriodicalId":19814,"journal":{"name":"Pediatric Cardiology","volume":" ","pages":"727-735"},"PeriodicalIF":1.5,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141301260","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Treatment of Primary Cardiac Tumors in Children: A Single Center 18-Year Experience. 儿童原发性心脏肿瘤的治疗：单中心 18 年经验

IF 1.5 4区医学

Pediatric Cardiology Pub Date : 2025-03-01 Epub Date: 2024-05-07 DOI: 10.1007/s00246-024-03493-x

Ok Jeong Lee, Ilkun Park, Ji-Hyuk Yang, I-Seok Kang, June Huh, Jinyoung Song, Tae-Gook Jun

{"title":"Treatment of Primary Cardiac Tumors in Children: A Single Center 18-Year Experience.","authors":"Ok Jeong Lee, Ilkun Park, Ji-Hyuk Yang, I-Seok Kang, June Huh, Jinyoung Song, Tae-Gook Jun","doi":"10.1007/s00246-024-03493-x","DOIUrl":"10.1007/s00246-024-03493-x","url":null,"abstract":"This study aimed to compare the clinical characteristics and courses of pediatric patients with cardiac tumors in nonoperative and operative groups to help guide treatment decisions. We reviewed the medical records of patients diagnosed with primary pediatric cardiac tumors at our institution between 2003 and 2020. Demographic data, clinical characteristics, and follow-up data between the operation and nonoperation groups were compared. A total of 56 patients were included in the study. Thirteen patients underwent surgery. The median age was 1.4 months (range, 1 to 18 years). The patients in the operation group had more frequent symptoms or signs, such as desaturation, respiratory difficulty, murmur, a higher mass area/chamber area (MC) ratio, decreased ventricular contractility, and significant ventricular outflow tract obstruction (VOTO). An MC ratio of 0.568 was the cutoff value for differentiating patients with symptoms or signs of heart failure and decreased ventricular contractility. At the last follow-up, all patients had good ventricular contractility except one patient in the operative group with fibroma. In the non-operative group, rhabdomyomas often regressed spontaneously, while fibromas often increased in size. Two patients in the nonoperative group died. In the operative group, there was no early or late mortality or tumor recurrence. In this study, patients had good outcomes with or without surgery, even when the tumor was large, or surgery was performed in early infancy.","PeriodicalId":19814,"journal":{"name":"Pediatric Cardiology","volume":" ","pages":"719-726"},"PeriodicalIF":1.5,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140866957","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0