Astrid-Marie De Souza, Kathryn R Armstrong, Kimberly Hoskins, Nicholas Tran, Kaelan C Naylor, Hilary V Romans, James E Potts, Martin C Hosking, David C Clarke
{"title":"有氧适能与先天性心脏病儿童运动参与有关","authors":"Astrid-Marie De Souza, Kathryn R Armstrong, Kimberly Hoskins, Nicholas Tran, Kaelan C Naylor, Hilary V Romans, James E Potts, Martin C Hosking, David C Clarke","doi":"10.1007/s00246-025-04014-0","DOIUrl":null,"url":null,"abstract":"<p><p>Anatomical and physiological differences in structural heart lesions may affect peak aerobic capacity ( <math><mover><mi>V</mi> <mo>˙</mo></mover> </math> O<sub>2peak</sub>) and influence sports participation in children with congenital heart disease (CHD). We hypothesized that a higher frequency of sports participation would be associated with higher <math> <mrow><mover><mi>V</mi> <mo>˙</mo></mover> <msub><mi>O</mi> <mrow><mn>2</mn> <mi>p</mi> <mi>e</mi> <mi>a</mi> <mi>k</mi></mrow> </msub> </mrow> </math> in these patients. A two-year, single-center, retrospective review (May 2016-November 2018) was conducted in CHD patients who had a maximal cardiopulmonary exercise test (CPET) and documented sport participation. Sports participation was categorized into 3 groups: 0-1 days/week; 2-3 days/week; and ≥ 4 days/week. <math><mover><mi>V</mi> <mo>˙</mo></mover> </math> O<sub>2peak</sub> z-scores, % <math><mover><mi>V</mi> <mo>˙</mo></mover> </math> O<sub>2</sub> at gas exchange threshold ( <math> <mrow><mover><mi>V</mi> <mo>˙</mo></mover> <msub><mi>O</mi> <mrow><mn>2</mn> <mi>G</mi> <mi>E</mi> <mi>T</mi></mrow> </msub> </mrow> </math> ), and O<sub>2</sub> pulse were calculated. Z-scores were calculated based on a reference population. Means and standard deviation (SD) are reported. p < 0.05 was considered statistically significant. In our study cohort (n = 56), <math><mover><mi>V</mi> <mo>˙</mo></mover> </math> O<sub>2peak</sub> z-score was - 1.01 ± 0.95; 83% had a z-score within ± 2 SD, while 59% were within one SD. The overall regression for sport participation with <math> <mrow><mover><mi>V</mi> <mo>˙</mo></mover> <msub><mi>O</mi> <mrow><mn>2</mn> <mi>p</mi> <mi>e</mi> <mi>a</mi> <mi>k</mi></mrow> </msub> </mrow> </math> and <math> <mrow><mover><mi>V</mi> <mo>˙</mo></mover> <msub><mi>O</mi> <mrow><mn>2</mn> <mi>G</mi> <mi>E</mi> <mi>T</mi></mrow> </msub> </mrow> </math> was statistically significant (R<sup>2</sup> = 0.40, F(4, 54) = 11.44, p = < .0001) and (R<sup>2</sup> = 0.17, F(4, 54) = 3.46, p = 0.0227), respectively. There was a significant main effect for O<sub>2</sub> pulse (R<sup>2</sup> = 0.41, F(4, 52) = 11.91, p < 0.0001) but not for HR<sub>peak</sub> (p = 0.86), SBP<sub>peak</sub> (p = 0.74) or DBP<sub>peak</sub> (p = 0.94). <math><mover><mi>V</mi> <mo>˙</mo></mover> </math> O<sub>2peak</sub> is higher in those who participate in sports compared to those who do not. It is unclear whether those with a higher <math><mover><mi>V</mi> <mo>˙</mo></mover> </math> O<sub>2peak</sub> are more inclined to participate in sports or whether sports participation leads to a higher <math><mover><mi>V</mi> <mo>˙</mo></mover> </math> O<sub>2peak</sub>.</p>","PeriodicalId":19814,"journal":{"name":"Pediatric Cardiology","volume":" ","pages":""},"PeriodicalIF":1.4000,"publicationDate":"2025-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Aerobic Fitness is Related to Sports Participation in Children with Congenital Heart Disease.\",\"authors\":\"Astrid-Marie De Souza, Kathryn R Armstrong, Kimberly Hoskins, Nicholas Tran, Kaelan C Naylor, Hilary V Romans, James E Potts, Martin C Hosking, David C Clarke\",\"doi\":\"10.1007/s00246-025-04014-0\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Anatomical and physiological differences in structural heart lesions may affect peak aerobic capacity ( <math><mover><mi>V</mi> <mo>˙</mo></mover> </math> O<sub>2peak</sub>) and influence sports participation in children with congenital heart disease (CHD). We hypothesized that a higher frequency of sports participation would be associated with higher <math> <mrow><mover><mi>V</mi> <mo>˙</mo></mover> <msub><mi>O</mi> <mrow><mn>2</mn> <mi>p</mi> <mi>e</mi> <mi>a</mi> <mi>k</mi></mrow> </msub> </mrow> </math> in these patients. A two-year, single-center, retrospective review (May 2016-November 2018) was conducted in CHD patients who had a maximal cardiopulmonary exercise test (CPET) and documented sport participation. Sports participation was categorized into 3 groups: 0-1 days/week; 2-3 days/week; and ≥ 4 days/week. <math><mover><mi>V</mi> <mo>˙</mo></mover> </math> O<sub>2peak</sub> z-scores, % <math><mover><mi>V</mi> <mo>˙</mo></mover> </math> O<sub>2</sub> at gas exchange threshold ( <math> <mrow><mover><mi>V</mi> <mo>˙</mo></mover> <msub><mi>O</mi> <mrow><mn>2</mn> <mi>G</mi> <mi>E</mi> <mi>T</mi></mrow> </msub> </mrow> </math> ), and O<sub>2</sub> pulse were calculated. Z-scores were calculated based on a reference population. Means and standard deviation (SD) are reported. p < 0.05 was considered statistically significant. In our study cohort (n = 56), <math><mover><mi>V</mi> <mo>˙</mo></mover> </math> O<sub>2peak</sub> z-score was - 1.01 ± 0.95; 83% had a z-score within ± 2 SD, while 59% were within one SD. The overall regression for sport participation with <math> <mrow><mover><mi>V</mi> <mo>˙</mo></mover> <msub><mi>O</mi> <mrow><mn>2</mn> <mi>p</mi> <mi>e</mi> <mi>a</mi> <mi>k</mi></mrow> </msub> </mrow> </math> and <math> <mrow><mover><mi>V</mi> <mo>˙</mo></mover> <msub><mi>O</mi> <mrow><mn>2</mn> <mi>G</mi> <mi>E</mi> <mi>T</mi></mrow> </msub> </mrow> </math> was statistically significant (R<sup>2</sup> = 0.40, F(4, 54) = 11.44, p = < .0001) and (R<sup>2</sup> = 0.17, F(4, 54) = 3.46, p = 0.0227), respectively. There was a significant main effect for O<sub>2</sub> pulse (R<sup>2</sup> = 0.41, F(4, 52) = 11.91, p < 0.0001) but not for HR<sub>peak</sub> (p = 0.86), SBP<sub>peak</sub> (p = 0.74) or DBP<sub>peak</sub> (p = 0.94). <math><mover><mi>V</mi> <mo>˙</mo></mover> </math> O<sub>2peak</sub> is higher in those who participate in sports compared to those who do not. It is unclear whether those with a higher <math><mover><mi>V</mi> <mo>˙</mo></mover> </math> O<sub>2peak</sub> are more inclined to participate in sports or whether sports participation leads to a higher <math><mover><mi>V</mi> <mo>˙</mo></mover> </math> O<sub>2peak</sub>.</p>\",\"PeriodicalId\":19814,\"journal\":{\"name\":\"Pediatric Cardiology\",\"volume\":\" \",\"pages\":\"\"},\"PeriodicalIF\":1.4000,\"publicationDate\":\"2025-09-25\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Pediatric Cardiology\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1007/s00246-025-04014-0\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"CARDIAC & CARDIOVASCULAR SYSTEMS\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Pediatric Cardiology","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1007/s00246-025-04014-0","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"CARDIAC & CARDIOVASCULAR SYSTEMS","Score":null,"Total":0}
引用次数: 0
摘要
心脏结构病变的解剖和生理差异可能影响先天性心脏病(CHD)患儿的峰值有氧能力(V˙o2峰值)并影响运动参与。我们假设,在这些患者中,更高频率的运动参与将与更高的V˙o2 p e a k相关。一项为期两年的单中心回顾性研究(2016年5月至2018年11月)对进行最大心肺运动试验(CPET)并记录参加运动的冠心病患者进行了研究。参与体育活动分为3组:每周0-1天;2 - 3天/周;≥4天/周。计算V˙O2峰z分数、气体交换阈值(V˙O2 2g G E T) % V˙O2和O2脉冲。z分数是根据参考人群计算的。报告均值和标准差(SD)。p V˙o2峰z-score为- 1.01±0.95;83%的z-score在±2个标准差范围内,59%的z-score在1个标准差范围内。运动参与与V˙O˙O˙e˙k和V˙O˙G˙e˙T的整体回归分别具有统计学意义(R2 = 0.40, F(4,54) = 11.44, p = 2 = 0.17, F(4,54) = 3.46, p = 0.0227)。O2脉冲(R2 = 0.41, F(4,52) = 11.91)、p峰(p = 0.86)、SBPpeak (p = 0.74)、DBPpeak (p = 0.94)均有显著主效应。参加体育运动的人的V˙o2峰值高于不参加体育运动的人。目前尚不清楚是具有较高V˙o2峰的人更倾向于参加体育运动,还是体育运动导致更高的V˙o2峰。
Aerobic Fitness is Related to Sports Participation in Children with Congenital Heart Disease.
Anatomical and physiological differences in structural heart lesions may affect peak aerobic capacity ( O2peak) and influence sports participation in children with congenital heart disease (CHD). We hypothesized that a higher frequency of sports participation would be associated with higher in these patients. A two-year, single-center, retrospective review (May 2016-November 2018) was conducted in CHD patients who had a maximal cardiopulmonary exercise test (CPET) and documented sport participation. Sports participation was categorized into 3 groups: 0-1 days/week; 2-3 days/week; and ≥ 4 days/week. O2peak z-scores, % O2 at gas exchange threshold ( ), and O2 pulse were calculated. Z-scores were calculated based on a reference population. Means and standard deviation (SD) are reported. p < 0.05 was considered statistically significant. In our study cohort (n = 56), O2peak z-score was - 1.01 ± 0.95; 83% had a z-score within ± 2 SD, while 59% were within one SD. The overall regression for sport participation with and was statistically significant (R2 = 0.40, F(4, 54) = 11.44, p = < .0001) and (R2 = 0.17, F(4, 54) = 3.46, p = 0.0227), respectively. There was a significant main effect for O2 pulse (R2 = 0.41, F(4, 52) = 11.91, p < 0.0001) but not for HRpeak (p = 0.86), SBPpeak (p = 0.74) or DBPpeak (p = 0.94). O2peak is higher in those who participate in sports compared to those who do not. It is unclear whether those with a higher O2peak are more inclined to participate in sports or whether sports participation leads to a higher O2peak.
期刊介绍:
The editor of Pediatric Cardiology welcomes original manuscripts concerning all aspects of heart disease in infants, children, and adolescents, including embryology and anatomy, physiology and pharmacology, biochemistry, pathology, genetics, radiology, clinical aspects, investigative cardiology, electrophysiology and echocardiography, and cardiac surgery. Articles which may include original articles, review articles, letters to the editor etc., must be written in English and must be submitted solely to Pediatric Cardiology.