Astrid-Marie De Souza, Kathryn R Armstrong, Kimberly Hoskins, Nicholas Tran, Kaelan C Naylor, Hilary V Romans, James E Potts, Martin C Hosking, David C Clarke
{"title":"Aerobic Fitness is Related to Sports Participation in Children with Congenital Heart Disease.","authors":"Astrid-Marie De Souza, Kathryn R Armstrong, Kimberly Hoskins, Nicholas Tran, Kaelan C Naylor, Hilary V Romans, James E Potts, Martin C Hosking, David C Clarke","doi":"10.1007/s00246-025-04014-0","DOIUrl":null,"url":null,"abstract":"<p><p>Anatomical and physiological differences in structural heart lesions may affect peak aerobic capacity ( <math><mover><mi>V</mi> <mo>˙</mo></mover> </math> O<sub>2peak</sub>) and influence sports participation in children with congenital heart disease (CHD). We hypothesized that a higher frequency of sports participation would be associated with higher <math> <mrow><mover><mi>V</mi> <mo>˙</mo></mover> <msub><mi>O</mi> <mrow><mn>2</mn> <mi>p</mi> <mi>e</mi> <mi>a</mi> <mi>k</mi></mrow> </msub> </mrow> </math> in these patients. A two-year, single-center, retrospective review (May 2016-November 2018) was conducted in CHD patients who had a maximal cardiopulmonary exercise test (CPET) and documented sport participation. Sports participation was categorized into 3 groups: 0-1 days/week; 2-3 days/week; and ≥ 4 days/week. <math><mover><mi>V</mi> <mo>˙</mo></mover> </math> O<sub>2peak</sub> z-scores, % <math><mover><mi>V</mi> <mo>˙</mo></mover> </math> O<sub>2</sub> at gas exchange threshold ( <math> <mrow><mover><mi>V</mi> <mo>˙</mo></mover> <msub><mi>O</mi> <mrow><mn>2</mn> <mi>G</mi> <mi>E</mi> <mi>T</mi></mrow> </msub> </mrow> </math> ), and O<sub>2</sub> pulse were calculated. Z-scores were calculated based on a reference population. Means and standard deviation (SD) are reported. p < 0.05 was considered statistically significant. In our study cohort (n = 56), <math><mover><mi>V</mi> <mo>˙</mo></mover> </math> O<sub>2peak</sub> z-score was - 1.01 ± 0.95; 83% had a z-score within ± 2 SD, while 59% were within one SD. The overall regression for sport participation with <math> <mrow><mover><mi>V</mi> <mo>˙</mo></mover> <msub><mi>O</mi> <mrow><mn>2</mn> <mi>p</mi> <mi>e</mi> <mi>a</mi> <mi>k</mi></mrow> </msub> </mrow> </math> and <math> <mrow><mover><mi>V</mi> <mo>˙</mo></mover> <msub><mi>O</mi> <mrow><mn>2</mn> <mi>G</mi> <mi>E</mi> <mi>T</mi></mrow> </msub> </mrow> </math> was statistically significant (R<sup>2</sup> = 0.40, F(4, 54) = 11.44, p = < .0001) and (R<sup>2</sup> = 0.17, F(4, 54) = 3.46, p = 0.0227), respectively. There was a significant main effect for O<sub>2</sub> pulse (R<sup>2</sup> = 0.41, F(4, 52) = 11.91, p < 0.0001) but not for HR<sub>peak</sub> (p = 0.86), SBP<sub>peak</sub> (p = 0.74) or DBP<sub>peak</sub> (p = 0.94). <math><mover><mi>V</mi> <mo>˙</mo></mover> </math> O<sub>2peak</sub> is higher in those who participate in sports compared to those who do not. It is unclear whether those with a higher <math><mover><mi>V</mi> <mo>˙</mo></mover> </math> O<sub>2peak</sub> are more inclined to participate in sports or whether sports participation leads to a higher <math><mover><mi>V</mi> <mo>˙</mo></mover> </math> O<sub>2peak</sub>.</p>","PeriodicalId":19814,"journal":{"name":"Pediatric Cardiology","volume":" ","pages":""},"PeriodicalIF":1.4000,"publicationDate":"2025-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Pediatric Cardiology","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1007/s00246-025-04014-0","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"CARDIAC & CARDIOVASCULAR SYSTEMS","Score":null,"Total":0}
引用次数: 0
Abstract
Anatomical and physiological differences in structural heart lesions may affect peak aerobic capacity ( O2peak) and influence sports participation in children with congenital heart disease (CHD). We hypothesized that a higher frequency of sports participation would be associated with higher in these patients. A two-year, single-center, retrospective review (May 2016-November 2018) was conducted in CHD patients who had a maximal cardiopulmonary exercise test (CPET) and documented sport participation. Sports participation was categorized into 3 groups: 0-1 days/week; 2-3 days/week; and ≥ 4 days/week. O2peak z-scores, % O2 at gas exchange threshold ( ), and O2 pulse were calculated. Z-scores were calculated based on a reference population. Means and standard deviation (SD) are reported. p < 0.05 was considered statistically significant. In our study cohort (n = 56), O2peak z-score was - 1.01 ± 0.95; 83% had a z-score within ± 2 SD, while 59% were within one SD. The overall regression for sport participation with and was statistically significant (R2 = 0.40, F(4, 54) = 11.44, p = < .0001) and (R2 = 0.17, F(4, 54) = 3.46, p = 0.0227), respectively. There was a significant main effect for O2 pulse (R2 = 0.41, F(4, 52) = 11.91, p < 0.0001) but not for HRpeak (p = 0.86), SBPpeak (p = 0.74) or DBPpeak (p = 0.94). O2peak is higher in those who participate in sports compared to those who do not. It is unclear whether those with a higher O2peak are more inclined to participate in sports or whether sports participation leads to a higher O2peak.
期刊介绍:
The editor of Pediatric Cardiology welcomes original manuscripts concerning all aspects of heart disease in infants, children, and adolescents, including embryology and anatomy, physiology and pharmacology, biochemistry, pathology, genetics, radiology, clinical aspects, investigative cardiology, electrophysiology and echocardiography, and cardiac surgery. Articles which may include original articles, review articles, letters to the editor etc., must be written in English and must be submitted solely to Pediatric Cardiology.