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Resveratrol activity on guinea pig isolated trachea from normal and albumin-sensitized animals 白藜芦醇对正常和白蛋白致敏豚鼠离体气管的活性研究
Pharmacological research communications Pub Date : 1988-12-01 Epub Date: 2009-02-19 DOI: 10.1016/S0031-6989(88)80846-4
E. Ragazzi, G. Froldi, G. Fassina
{"title":"Resveratrol activity on guinea pig isolated trachea from normal and albumin-sensitized animals","authors":"E. Ragazzi,&nbsp;G. Froldi,&nbsp;G. Fassina","doi":"10.1016/S0031-6989(88)80846-4","DOIUrl":"10.1016/S0031-6989(88)80846-4","url":null,"abstract":"<div><p>The relaxant effect of resveratrol on guinea pig isolated trachea (EC50=100 μM) was not due to interactions with histaminergic or cholinergic systems, but appeared to be influenced by beta-blockers, indomethacin and mepacrine. Antigen-induced contraction on sensitized trachea was partially antagonized by resveratrol. Resveratrol action may be partially related to arachidonic acid metabolism.</p></div>","PeriodicalId":19810,"journal":{"name":"Pharmacological research communications","volume":"20 ","pages":"Pages 79-82"},"PeriodicalIF":0.0,"publicationDate":"1988-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0031-6989(88)80846-4","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14043417","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 34
A comparative study of behavioural and autonomic effects of atropine and Atropa belladonna 阿托品和颠茄对行为和自主神经影响的比较研究
Pharmacological research communications Pub Date : 1988-12-01 Epub Date: 2009-02-19 DOI: 10.1016/S0031-6989(88)80839-7
Mazzanti G. , Tita B. , Bolle P. , Bonanomi M. , Piccinelli D.
{"title":"A comparative study of behavioural and autonomic effects of atropine and Atropa belladonna","authors":"Mazzanti G. ,&nbsp;Tita B. ,&nbsp;Bolle P. ,&nbsp;Bonanomi M. ,&nbsp;Piccinelli D.","doi":"10.1016/S0031-6989(88)80839-7","DOIUrl":"10.1016/S0031-6989(88)80839-7","url":null,"abstract":"<div><p>Atropa belladonna L. (Solanaceae) tincture was compared with atropine for its anticholinergic activity, both in vivo and in vitro. In all tests, the biological activity of A. belladonna resulted greater than that suggested by its alkaloid content. The results suggest the presence in A. belladonna leaves of unknown compounds with a significant biological activity.</p></div>","PeriodicalId":19810,"journal":{"name":"Pharmacological research communications","volume":"20 ","pages":"Pages 49-53"},"PeriodicalIF":0.0,"publicationDate":"1988-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0031-6989(88)80839-7","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14376285","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
BN-52021 protects guinea-pig from heart anaphylaxis BN-52021保护豚鼠免受心脏过敏反应
Pharmacological research communications Pub Date : 1988-12-01 Epub Date: 2009-02-19 DOI: 10.1016/S0031-6989(88)80845-2
Magni F., Rossoni G., Berti F.
{"title":"BN-52021 protects guinea-pig from heart anaphylaxis","authors":"Magni F.,&nbsp;Rossoni G.,&nbsp;Berti F.","doi":"10.1016/S0031-6989(88)80845-2","DOIUrl":"10.1016/S0031-6989(88)80845-2","url":null,"abstract":"<div><p>BN-52021 preserves “in vitro” the actively sensitized guinea-pig heart from the immunological reaction. This ginkgolide reduces mediator release (histamine, thromboxane-A<sub>2</sub> and slow reacting substance of anaphylaxis) in a dose-dependent manner, particularly that of histamine. These results evidence either an important role for PAF in guinea pig anaphylaxis or a wider spectrum of activity for BN-52021.</p></div>","PeriodicalId":19810,"journal":{"name":"Pharmacological research communications","volume":"20 ","pages":"Pages 75-78"},"PeriodicalIF":0.0,"publicationDate":"1988-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0031-6989(88)80845-2","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14376291","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 43
Head-twitch and forepaw-shake responses after single and repeated treatment with rolipram: Interaction with noradrenergic and dopaminergic agonists and antagonists 罗利普兰单次和重复治疗后的头抽搐和前爪抖动反应:与去甲肾上腺素能和多巴胺能激动剂和拮抗剂的相互作用
Pharmacological research communications Pub Date : 1988-12-01 Epub Date: 2007-09-04 DOI: 10.1016/S0031-6989(88)80759-8
A. Flugy, M. Gagliano, S. La Rocca, V. Novara, G. Cannizzaro
{"title":"Head-twitch and forepaw-shake responses after single and repeated treatment with rolipram: Interaction with noradrenergic and dopaminergic agonists and antagonists","authors":"A. Flugy,&nbsp;M. Gagliano,&nbsp;S. La Rocca,&nbsp;V. Novara,&nbsp;G. Cannizzaro","doi":"10.1016/S0031-6989(88)80759-8","DOIUrl":"10.1016/S0031-6989(88)80759-8","url":null,"abstract":"","PeriodicalId":19810,"journal":{"name":"Pharmacological research communications","volume":"20 12","pages":"Pages 1127-1128"},"PeriodicalIF":0.0,"publicationDate":"1988-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0031-6989(88)80759-8","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14042084","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prostaglandins and prostaglandin-like compounds in plants 植物中的前列腺素和类似前列腺素的化合物
Pharmacological research communications Pub Date : 1988-12-01 Epub Date: 2009-02-19 DOI: 10.1016/S0031-6989(88)80851-8
E. Bosisio
{"title":"Prostaglandins and prostaglandin-like compounds in plants","authors":"E. Bosisio","doi":"10.1016/S0031-6989(88)80851-8","DOIUrl":"10.1016/S0031-6989(88)80851-8","url":null,"abstract":"","PeriodicalId":19810,"journal":{"name":"Pharmacological research communications","volume":"20 ","pages":"Pages 99-103"},"PeriodicalIF":0.0,"publicationDate":"1988-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0031-6989(88)80851-8","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14205337","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Pharmacological analysis of intrinsic neural control of rat duodenum motility in vitro 体外大鼠十二指肠运动内在神经控制的药理学分析
Pharmacological research communications Pub Date : 1988-12-01 Epub Date: 2007-09-04 DOI: 10.1016/S0031-6989(88)80749-5
R. Serio, A. Postorino
{"title":"Pharmacological analysis of intrinsic neural control of rat duodenum motility in vitro","authors":"R. Serio,&nbsp;A. Postorino","doi":"10.1016/S0031-6989(88)80749-5","DOIUrl":"10.1016/S0031-6989(88)80749-5","url":null,"abstract":"","PeriodicalId":19810,"journal":{"name":"Pharmacological research communications","volume":"20 12","pages":"Pages 1107-1108"},"PeriodicalIF":0.0,"publicationDate":"1988-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0031-6989(88)80749-5","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14341180","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Nigral control of hippocampal epilepsy: a dopaminergic hypothesis 海马癫痫的神经控制:多巴胺能假说
Pharmacological research communications Pub Date : 1988-12-01 Epub Date: 2007-09-04 DOI: 10.1016/S0031-6989(88)80750-1
Sabatino Michele, Giuseppe Caravaglios, Vittorio La Grutta
{"title":"Nigral control of hippocampal epilepsy: a dopaminergic hypothesis","authors":"Sabatino Michele,&nbsp;Giuseppe Caravaglios,&nbsp;Vittorio La Grutta","doi":"10.1016/S0031-6989(88)80750-1","DOIUrl":"10.1016/S0031-6989(88)80750-1","url":null,"abstract":"","PeriodicalId":19810,"journal":{"name":"Pharmacological research communications","volume":"20 12","pages":"Pages 1109-1110"},"PeriodicalIF":0.0,"publicationDate":"1988-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0031-6989(88)80750-1","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14341181","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Correlation with 3H-MPP+ binding sites by debrisoquin and some analogues in mouse brain 碎片醌及其类似物与小鼠脑内3H-MPP+结合位点的相关性
Pharmacological research communications Pub Date : 1988-12-01 Epub Date: 2007-09-04 DOI: 10.1016/S0031-6989(88)80748-3
S. Ruju, M. Del Zompo, M.P. Piccardi, R. Maggio, G.U. Corsini
{"title":"Correlation with 3H-MPP+ binding sites by debrisoquin and some analogues in mouse brain","authors":"S. Ruju,&nbsp;M. Del Zompo,&nbsp;M.P. Piccardi,&nbsp;R. Maggio,&nbsp;G.U. Corsini","doi":"10.1016/S0031-6989(88)80748-3","DOIUrl":"10.1016/S0031-6989(88)80748-3","url":null,"abstract":"","PeriodicalId":19810,"journal":{"name":"Pharmacological research communications","volume":"20 12","pages":"Pages 1105-1106"},"PeriodicalIF":0.0,"publicationDate":"1988-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0031-6989(88)80748-3","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14392009","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Algae as possible sources of antitumoural agents. Preliminary evaluation of the “in vitro” cytostatic activity of crude extracts 藻类可能是抗肿瘤药物的来源。粗提物体外抑细胞活性的初步评价
Pharmacological research communications Pub Date : 1988-12-01 Epub Date: 2009-02-19 DOI: 10.1016/S0031-6989(88)80834-8
V. Kosovel , A. Avanzini , V. Scarcia , A. Furlani
{"title":"Algae as possible sources of antitumoural agents. Preliminary evaluation of the “in vitro” cytostatic activity of crude extracts","authors":"V. Kosovel ,&nbsp;A. Avanzini ,&nbsp;V. Scarcia ,&nbsp;A. Furlani","doi":"10.1016/S0031-6989(88)80834-8","DOIUrl":"10.1016/S0031-6989(88)80834-8","url":null,"abstract":"<div><p>Aqueous, ethanolic and chloroformic extracts of 13 algae from the Gulf of Trieste (North Adriatic Sea) were assayed <u>in vitro</u> against human tumour established cell line (KB). Some of them exhibit a noteworthy cytostatic activity, in particular <u>Dictyopteris membranacea</u> (Stackh.)Batt., which significantly inhibits the growth of the cell cultures in all the three diffe<u>r</u> ent crude extracts, was quantitatively screened in different periods of the year for the presence of cytostatic compound(s).</p></div>","PeriodicalId":19810,"journal":{"name":"Pharmacological research communications","volume":"20 ","pages":"Pages 27-31"},"PeriodicalIF":0.0,"publicationDate":"1988-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0031-6989(88)80834-8","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14376280","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 17
Papaver somniferum L. var. album D.C. cultivated in Sicily: Phytochemical Investigation and use 西西里岛栽培罂粟:植物化学研究与利用
Pharmacological research communications Pub Date : 1988-12-01 Epub Date: 2009-02-19 DOI: 10.1016/S0031-6989(88)80857-9
Attaguile G. , Barbagallo C. , Savoca F.
{"title":"Papaver somniferum L. var. album D.C. cultivated in Sicily: Phytochemical Investigation and use","authors":"Attaguile G. ,&nbsp;Barbagallo C. ,&nbsp;Savoca F.","doi":"10.1016/S0031-6989(88)80857-9","DOIUrl":"10.1016/S0031-6989(88)80857-9","url":null,"abstract":"<div><p>The authors evaluated the vegetative growth and alkaloid content of the Papaver somniferum L. var. album D.C. capsules cultivated in Assoro (Enna) Sicily, in relation to the geographical position, environmental conditions and soil type. Gas chromatography revealed low alkaloid opiate producing capacity which makes cultivation for therapeutic and toxicologic purposes uneconomic. On the contrary, the elevated production of capsules containing numerous seeds justifies its cultivation for extraction of oil for the food industry and paint production.</p><p>The results suggest that the cultivation of Papaver somniferum studied is used for baking traditional cakes and bread.</p></div>","PeriodicalId":19810,"journal":{"name":"Pharmacological research communications","volume":"20 ","pages":"Pages 129-133"},"PeriodicalIF":0.0,"publicationDate":"1988-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0031-6989(88)80857-9","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14377595","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
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