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Pharmacological research communications最新文献

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Pertussis toxin inhibits the behavioural and ECoG effects induced by clonidine and yohimbine after their microinfusion into the locus coeruleus 百日咳毒素可抑制可乐定和育亨宾微量注入蓝斑后引起的行为和ECoG效应
Pharmacological research communications Pub Date : 1988-12-01 DOI: 10.1016/S0031-6989(88)80743-4
De Sarro G.B., Ascioti C., Audino M.G., Nisticò G.
{"title":"Pertussis toxin inhibits the behavioural and ECoG effects induced by clonidine and yohimbine after their microinfusion into the locus coeruleus","authors":"De Sarro G.B., Ascioti C., Audino M.G., Nisticò G.","doi":"10.1016/S0031-6989(88)80743-4","DOIUrl":"10.1016/S0031-6989(88)80743-4","url":null,"abstract":"","PeriodicalId":19810,"journal":{"name":"Pharmacological research communications","volume":"20 12","pages":"Pages 1095-1096"},"PeriodicalIF":0.0,"publicationDate":"1988-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0031-6989(88)80743-4","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14341178","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Radioactivity from 137Cs in plant drugs and their preparations after chernobyl 切尔诺贝利事故后植物药物及其制剂中137Cs的放射性
Pharmacological research communications Pub Date : 1988-12-01 DOI: 10.1016/S0031-6989(88)80862-2
A. Menghini , R. Borio , S. Chiocchini , P. Scampoli
{"title":"Radioactivity from 137Cs in plant drugs and their preparations after chernobyl","authors":"A. Menghini ,&nbsp;R. Borio ,&nbsp;S. Chiocchini ,&nbsp;P. Scampoli","doi":"10.1016/S0031-6989(88)80862-2","DOIUrl":"10.1016/S0031-6989(88)80862-2","url":null,"abstract":"<div><p>The <sup>137</sup>Cs contents was determined in 406 plant drug samples harvested in 1986 and 1987 after the Chernobyl accident and in their preparations. Very high values were found in drugs produced in Eastern Europe and in Italy. The decoction contain about 80% of <sup>137</sup>Cs present in the drugs.</p></div>","PeriodicalId":19810,"journal":{"name":"Pharmacological research communications","volume":"20 ","pages":"Pages 155-159"},"PeriodicalIF":0.0,"publicationDate":"1988-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0031-6989(88)80862-2","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14376279","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Results of Smilax macrophylla Vers. in normal hyperuricemic and hyperuricosuric rats 菝葜的研究结果。正常高尿酸血症大鼠和高尿酸大鼠
Pharmacological research communications Pub Date : 1988-12-01 DOI: 10.1016/S0031-6989(88)80841-5
D. Giachetti, I. Taddei, E. Taddei
{"title":"Results of Smilax macrophylla Vers. in normal hyperuricemic and hyperuricosuric rats","authors":"D. Giachetti,&nbsp;I. Taddei,&nbsp;E. Taddei","doi":"10.1016/S0031-6989(88)80841-5","DOIUrl":"https://doi.org/10.1016/S0031-6989(88)80841-5","url":null,"abstract":"<div><p><u>Smilax macrophylla</u> Vers., administred per os at the doses of 1 or 2 g/kg in normal rats or in rats made hyperuricemic and hyperuricosuric by potassium oxonate (250 mg/Kg p.o.) or fructose (4 g/Kg p.o.) does not modify diuresis, but increases the excretion of uric acid and allantoin in normal rats and in those pretreated with fructose, whereas it is inactive in oxonate pretreated rats. Allantoinemia is not modified by fructose or oxonate, whereas uricemia is modified.</p></div>","PeriodicalId":19810,"journal":{"name":"Pharmacological research communications","volume":"20 ","pages":"Pages 59-62"},"PeriodicalIF":0.0,"publicationDate":"1988-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0031-6989(88)80841-5","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89998759","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
2nd inter-regional meeting of the Basilicata, Calabria, Campania, Puglia, Sardegna, Sicilia Group of the Italian Pharmacological Society. Cagliari, May 30-31, 1988. Communications. 意大利药理学学会Basilicata, Calabria, Campania, Puglia, Sardegna, Sicilia小组第二次区域间会议。1988年5月30日至31日，卡利亚里。通信。
Pharmacological research communications Pub Date : 1988-12-01
{"title":"2nd inter-regional meeting of the Basilicata, Calabria, Campania, Puglia, Sardegna, Sicilia Group of the Italian Pharmacological Society. Cagliari, May 30-31, 1988. Communications.","authors":"","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":19810,"journal":{"name":"Pharmacological research communications","volume":"20 12","pages":"1061-128"},"PeriodicalIF":0.0,"publicationDate":"1988-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14341171","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Neurochemical and behavioral effects of cadmium alone or associated with selenium in the rat 镉单独或与硒结合对大鼠神经化学和行为的影响
Pharmacological research communications Pub Date : 1988-12-01 DOI: 10.1016/S0031-6989(88)80727-6
A. Agriolas, W. Fratta, S. Luciani, E. Marmo, M. Miele , M.S. Desolf , P. Demontis , G. Esposito , A. Congiu , V. Anania
{"title":"Neurochemical and behavioral effects of cadmium alone or associated with selenium in the rat","authors":"A. Agriolas,&nbsp;W. Fratta,&nbsp;S. Luciani,&nbsp;E. Marmo,&nbsp;M. Miele ,&nbsp;M.S. Desolf ,&nbsp;P. Demontis ,&nbsp;G. Esposito ,&nbsp;A. Congiu ,&nbsp;V. Anania","doi":"10.1016/S0031-6989(88)80727-6","DOIUrl":"10.1016/S0031-6989(88)80727-6","url":null,"abstract":"","PeriodicalId":19810,"journal":{"name":"Pharmacological research communications","volume":"20 12","pages":"Pages 1063-1064"},"PeriodicalIF":0.0,"publicationDate":"1988-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0031-6989(88)80727-6","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14341172","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
Study on the action mechanism of some flavones through registration of intracardiac potentials in anesthetized dogs 通过对麻醉犬心内电位的记录研究某些黄酮的作用机制
Pharmacological research communications Pub Date : 1988-12-01 DOI: 10.1016/S0031-6989(88)80732-X
F. Occhiuto , G. Busà , A. De Pasquale
{"title":"Study on the action mechanism of some flavones through registration of intracardiac potentials in anesthetized dogs","authors":"F. Occhiuto ,&nbsp;G. Busà ,&nbsp;A. De Pasquale","doi":"10.1016/S0031-6989(88)80732-X","DOIUrl":"10.1016/S0031-6989(88)80732-X","url":null,"abstract":"","PeriodicalId":19810,"journal":{"name":"Pharmacological research communications","volume":"20 12","pages":"Pages 1073-1074"},"PeriodicalIF":0.0,"publicationDate":"1988-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0031-6989(88)80732-X","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14341176","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
Glycosides of the Magydaris Pastinacea L. 马兜草苷类化合物的研究。
Pharmacological research communications Pub Date : 1988-12-01 DOI: 10.1016/S0031-6989(88)80853-1
Cerri R., Dessì G., Manconi P.M., Serra D., Pau A.
{"title":"Glycosides of the Magydaris Pastinacea L.","authors":"Cerri R.,&nbsp;Dessì G.,&nbsp;Manconi P.M.,&nbsp;Serra D.,&nbsp;Pau A.","doi":"10.1016/S0031-6989(88)80853-1","DOIUrl":"10.1016/S0031-6989(88)80853-1","url":null,"abstract":"<div><p>From the alcoholic extract of fresh rhizomes from <u>Magydaris Pastinacea</u> the glycosidic fraction was separated: it appears to be made up of seven different constituents one of which, 7-0-β-glucopyranosil-8(2′,3′-dihydroxy-3′methyl)-butylcoumarin isolated and identified by us, is relatively more abundant.</p></div>","PeriodicalId":19810,"journal":{"name":"Pharmacological research communications","volume":"20 ","pages":"Pages 109-112"},"PeriodicalIF":0.0,"publicationDate":"1988-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0031-6989(88)80853-1","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14377591","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
The PAF-acether receptor antagonist BN-52021 inhibits mediator release during guinea-PIG active lung anaphylaxis paf -乙醚受体拮抗剂BN-52021抑制豚鼠活动性肺过敏反应期间介质释放
Pharmacological research communications Pub Date : 1988-12-01 DOI: 10.1016/S0031-6989(88)80726-4
Berti F. , Galli G. , Magni F. , Rossoni G. , Villa L. , Puglisi L. , Pasargiklian R. , P. Braquet
{"title":"The PAF-acether receptor antagonist BN-52021 inhibits mediator release during guinea-PIG active lung anaphylaxis","authors":"Berti F. ,&nbsp;Galli G. ,&nbsp;Magni F. ,&nbsp;Rossoni G. ,&nbsp;Villa L. ,&nbsp;Puglisi L. ,&nbsp;Pasargiklian R. ,&nbsp;P. Braquet","doi":"10.1016/S0031-6989(88)80726-4","DOIUrl":"10.1016/S0031-6989(88)80726-4","url":null,"abstract":"<div><p>An anaphylactic reaction was induced with the specific antigen (1 mg Ovalbumin) in perfused lungs from actively sensitized guinea-pigs in order to evaluate the ability of the ginkgolide BN-52021 (0.4, 4, 40 ug/ml) to modulate the mediator release. The ginkgolide reduces in a dose dependent manner the release of histamine (22%, 45% and 75% of inhibition), TXB<sub>2</sub> (77% of inhibition at the maximal dose used) and of SRS-A to a lower extent (only 33% at the higher dose). BN-52021 was still powerful in reducing histamine release induced by immunological reaction in indomethacin treated animals. In conclusion, the present “in-vitro” results confirm the beneficial activity of this ginkgolide, already demonstrated by the same Authors in “in-vivo” experiment, in anaphylactic reactions, and further substantiate the wider spectrum of action of the ginkgolide beside its specific PAF receptor antagonistic activity.</p></div>","PeriodicalId":19810,"journal":{"name":"Pharmacological research communications","volume":"20 12","pages":"Pages 1047-1059"},"PeriodicalIF":0.0,"publicationDate":"1988-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0031-6989(88)80726-4","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13608256","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Receptor-mediated activation of tyrosine hydroxylase by corticotropin-releasing factor in striatal synaptosomes 纹状体突触体中促肾上腺皮质激素释放因子介导的酪氨酸羟化酶受体激活
Pharmacological research communications Pub Date : 1988-12-01 DOI: 10.1016/S0031-6989(88)80744-6
Maria C. Olianas, Pierlugi Onali
{"title":"Receptor-mediated activation of tyrosine hydroxylase by corticotropin-releasing factor in striatal synaptosomes","authors":"Maria C. Olianas,&nbsp;Pierlugi Onali","doi":"10.1016/S0031-6989(88)80744-6","DOIUrl":"10.1016/S0031-6989(88)80744-6","url":null,"abstract":"","PeriodicalId":19810,"journal":{"name":"Pharmacological research communications","volume":"20 12","pages":"Pages 1097-1098"},"PeriodicalIF":0.0,"publicationDate":"1988-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0031-6989(88)80744-6","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14042080","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Drugs from the sea 海上毒品
Pharmacological research communications Pub Date : 1988-12-01 DOI: 10.1016/S0031-6989(88)80832-4
Antonio Imbesi (Dean of the School of Pharmacy)
{"title":"Drugs from the sea","authors":"Antonio Imbesi (Dean of the School of Pharmacy)","doi":"10.1016/S0031-6989(88)80832-4","DOIUrl":"10.1016/S0031-6989(88)80832-4","url":null,"abstract":"","PeriodicalId":19810,"journal":{"name":"Pharmacological research communications","volume":"20 ","pages":"Pages 1-21"},"PeriodicalIF":0.0,"publicationDate":"1988-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0031-6989(88)80832-4","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14377589","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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