Pamukkale Medical Journal最新文献

{"title":"Effect of resin photopolymerization on primary teeth pulpal temperature change.","authors":"Y. Erdoğan, I. Ertuğrul","doi":"10.31362/patd.1257746","DOIUrl":"https://doi.org/10.31362/patd.1257746","url":null,"abstract":"Purpose: The polymerization of restorative materials has the potential to increase pulpal temperature and may result in damage to the health of pulpal tissue. The aim of this study is to investigate the pulpal temperature change of primary teeth with two LED light-curing units (Valo Cordless®, EliparTM DeepCure-S) and three restorative groups (Filtek™ Bulk Fill Flowable, Filtek™ Z250 Universal Restorative and empty cavity) by using a microcirculation model. \u0000Material and Methods: Ten sound human maxillary second primary molars were used. Standardized Class V cavity preparations were performed with a dentin thickness of 1 mm and restorative groups were cured with LED light-curing units. The highest temperature point in the pulp chamber was recorded. A repeated measures ANOVA and paired samples t-test were used for analysis of the data (𝑝","PeriodicalId":19789,"journal":{"name":"Pamukkale Medical Journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91110837","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Factors associated with freqeuncy and severity of COVID-19 in patients with axial spondyloarthritis","authors":"M. Pekdiker, M. Kara, Emrah Koç, G. Kimyon","doi":"10.31362/patd.1223660","DOIUrl":"https://doi.org/10.31362/patd.1223660","url":null,"abstract":"Purpose: The severe course of COVID-19 in individuals with chronic diseases has led to concerns in the management of rheumatic diseases during the pandemic therefore we aimed to define the factors associated with the frequency and severity of COVID-19 in patients with axial spondyloarthritis (axSpa) in this study. \u0000Materials-Methods: Patients with axSpa who were followed up in three tertiary hospitals and used their treatment regularly for at least six months were included. We assessed the relationship between axSpa associated variables such as disease duration time, radiological severity, treatment and COVID-19 outcomes. \u0000Results: A total of 833 patients with a mean disease duration of 109 months were analyzed; 64.5% had ankylosing spondylitis, 35.5% had non-radiographic axSpa diagnosis, and 59.4% of patients were treated with biologic agent . The frequency of COVID-19 was 23% (n: 192); only five pateints (0.5%) had a history of intensive care unit. Advanced age, hypertension (HT), and diabetes mellitus (DM) were found to be significantly more common in those with involvement in high resolution computed tomography (HRCT) (p:0.02, p:0.01, and p","PeriodicalId":19789,"journal":{"name":"Pamukkale Medical Journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-03-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73059234","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Relationship Between Problematic Internet Use of Adolescents and Their Level of Satisfaction with Family Life","authors":"Ayse Kalkan, Esin Cerit","doi":"10.31362/patd.1194209","DOIUrl":"https://doi.org/10.31362/patd.1194209","url":null,"abstract":"Purpose: This study aimed to determine the relationship between the level of problematic internet use of adolescents and their level of satisfaction with family life. \u0000Method: The research was conducted in a cross-sectional descriptive design. 508 volunteer students from among the students studying at the high schools in Yozgat city center participated in the research which was carried out in the 2021-2022 academic year.. Data were collected through Google Forms questionnaires sent to students' smartphones. \u0000Results: The results of the analysis revealed a significant negative relationship between the problematic internet use of adolescents and their level of satisfaction with family life. Accordingly, a significant difference was determined between the variables of family income, academic achievement, father's educational background and father's child-rearing attitudes and problematic internet use. Furthermore, a significant difference was determined between the variables of academic achievement, parents’ living together, father's educational background, father's working status, family's economic income and the level of satisfaction with family life. \u0000Conclusion: In this study, the significance of the family with regard to the development of adolescents as healthy internet users was emphasized; it was suggested that preventive, protective and educational studies should be carried out and that the use of different methods, including other possible predictors, should be included in follow-up studies.","PeriodicalId":19789,"journal":{"name":"Pamukkale Medical Journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75175597","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Psychometric Properties of the General Phubbing Scale in Adolescents","authors":"Erdal Görkem Gavcar, Ahmet Büber, Murat Balkıs, Çağlar Şimşek","doi":"10.31362/patd.1232372","DOIUrl":"https://doi.org/10.31362/patd.1232372","url":null,"abstract":"Purpose: Numerous studies indicate that the use of smartphones among adolescents has increased recently. Studies on phubbing generally focus on how parental phubbing affects adolescents. This study aims to contribute to the literature by revealing the validity and reliability of the scale measuring phubbing behavior in adolescents. \u0000 \u0000Material and Methods: The sample included 206 adolescents aged 12-17 who applied to Pamukkale University Medical Faculty Hospital Child and Adolescent Psychiatry Outpatient Clinics and Kırıkkale Yüksek İhtisas Hospital Child and Adolescent Psychiatry Outpatient Clinic. \u0000 \u0000Results: To evaluate the construct validity of the General Phubbing Scale (GPS) in adolescents, first and second level confirmatory factor analyses were performed. The data model fit was shown to be at an acceptable level. The general phubbing was negatively related to social connectedness and positively related to internet addiction. Test-retest analysis indicated that the subdimensions nomophobia, interpersonal conflict, self-isolation, problem acceptance, and total score were 0.82, 0.80, 0.71, 0.66 and 0.81, respectively. The coefficients of internal consistency for the subdimensions of nomophobia, interpersonal conflict, self-isolation, problem acceptance, and total score were 0.78, 0.85, 0.92, 0.77, and 0.94. Furthermore, it has been shown that the GPS structure was identical for both genders. \u0000 \u0000Conclusion: This study demonstrated that the GPS can be used as a valid and reliable measurement tool for determining general phubbing levels for the clinical adolescent sample.","PeriodicalId":19789,"journal":{"name":"Pamukkale Medical Journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87444603","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of quality of life and post-operative complications of our radical prostatectomy series for 5 years. 5 YILLIK RADİKAL PROSTATEKTOMİ SERİMİZİN POSTOPERATİF KOMPLİKASYON VE YAŞAM KALİTELERİNİN DEĞERLENDİRİLMESİ","authors":"Cihan Toktaş, I. Acar, Ö. L. Tuncay","doi":"10.31362/patd.1225431","DOIUrl":"https://doi.org/10.31362/patd.1225431","url":null,"abstract":"The aim of this study is to evaluate health status, erectile function, continence status and mental status of the patients. We also analyze demographic features and post-operative complications. We want to detect changings in surgical techniques and complication rates, so we will obtain accurate knowledges for the patients who will undergo radical prostatectomy in the future. \u000067 patient included to this study with permission of Pamukkale University ethic commission. We phoned patients and ask to come hospital to filling out forms and to ask few questiones. We suggest them to fill out generel health quality, IIEF, ICIQ and MMT forms. We also asked them how they decide to undergo operation, satisfaction and regret for treatment We record demographic and follow-up informations of patient from database of our hospital \u0000We found that the number of the patients who undergone radical prostatectomy increased over the years and the lenght of stay in hospital and the risk of additional operation for urethral stricture decreased over the yeary \u0000Data from our study were compatible with the existing literature- \u0000 \u0000 \u0000Çalışmamızın amacı kliniğimizde son 5 yılda yapılan radikal prostatektomi ameliyatlarının hastaların genel sağlık durumları, erektil fonksiyonları, kontinans durumları ve mental durumlarını değerlendirmek ayrıca hastaların demografik özellikleri ile post-operastif takiplerini retrospektif olarak değeılendirmektir. Bu değerlendirmeler sonucunda kliniğimizde yapılan radikal prostatektomi ameliyatlarının yıllar içinde teknik ve sonuçlar açısından değişimi saptanacak ayrıca önümüzdeki yıllarda bu ameliyatın önerileceği hasta grubuna sunulabilecek somut verilere ulaşılabilecektir. \u0000Çalışmaya Pamukkale Üniversitesi Tıbbi Etik kuruldan alınan izinle toplam 67 hasta dahil edildin Hastalar telefonla aranarak hastaneye çağıldı. Hastalara genel sağlık durumu, 11EF, ICIQ ve MMT sorgu formları uygulandı. Ayrıca hastalara operasyona karar aşamasındaki tutumları, tedavi memnuniyetleri ve aynı tedaviyi tekrar kabul edip etmeyecekleri soruldu„ Ardından hastaların operasyon ve operasyon sonrası takip bilgileri hastane hasta takip sisteminden kaydedildi, \u0000Çalışma kliniğimizin son 2 yılda radikal prostatektomi sayısında altış olduğu ayrıca vaka sayısında artışla birlikte hastaların hastanede kalış süıeleıinin ve darlık nedeniyle ek girişim riskinin azaldığı saptanmıştır. \u0000Çalışmamızdan elde edilen veriler mevcut literatür ile uyumlu saptanmıştır","PeriodicalId":19789,"journal":{"name":"Pamukkale Medical Journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85333722","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of the presence of SARS-CoV-2 in the aqueous humor and vitreous in patients undergoing combined phaco-vitrectomy surgery","authors":"Göksu Hande Naz Şimdivar, Emine Çiloğlu, T. Incekalan, Neşe ÇETİN DOĞAN, Nevzat Ünal, Hivda ÜlbeĞİ Polat, E. Akçael","doi":"10.31362/patd.1232525","DOIUrl":"https://doi.org/10.31362/patd.1232525","url":null,"abstract":"Purpose: To investigate the presence of virus in the aqueous humor and vitreous of patients undergoing elective combined cataract and pars plana vitrectomy during the Coronavirus disease 2019 (COVID-19) pandemic. \u0000Materials and methods: In this prospective cross-sectional study, of the patients to undergo elective surgery, those who had a negative severe acute respiratory syndrome coronavirus 2 ( SARS-CoV-2) nasal swab test 24-72 hours prior to the surgery and who were asymptomatic were included. SARS-CoV-2 IgG antibodies were evaluated in blood samples taken 24-72 hours before the operation. 0.1 cc of aqueous humor and 0.1 cc of vitreous fluid were aspirated at the beginning of the surgery. The presence of SARS-CoV-2 viral ribonucleic acid (RNA) was evaluated by real-time reverse transcriptase polymerase chain reaction (RT-PCR). \u0000Results: Of 66 participants, 39 were male (59.1%) while 27 were female (40.9%). Twenty five patients (37.8%) had a history of COVID-19 between 20 days - 60 days (mean 49 days) before the surgery. There were 58 patients (87.9%) with a history of vaccination before the operation and 8 patients (12.1%) without a history of vaccination. No SARS CoV 2 RNA was detected in the aqueous humor and vitreous samples of any patient. IgG against SARSCoV-2 was detected in 3 patients who had not been vaccinated against COVID-19 before and had no known history of COVID-19. \u0000Conclusion: We did not find any SARS-CoV-2 viral genetic material in the aqueous and vitreous fluids of asymptomatic participants whose nasal swab test was negative, even if they recently had COVID-19.","PeriodicalId":19789,"journal":{"name":"Pamukkale Medical Journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-03-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84335047","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of the frequency of MEFV gene variants in patients with a pre-diagnosis of Familial Mediterranean Fever (FMF) in southeast Turkey.","authors":"Derya Karaer, Bahtiyar Şahinoğlu, A. Gürler, K. Karaer","doi":"10.31362/patd.1255344","DOIUrl":"https://doi.org/10.31362/patd.1255344","url":null,"abstract":"Purpose: Familial Mediterranean Fever (FMF) is a hereditary auto inflammatory disease (MIM#249100). The most common symptoms are high fever, abdominal pain and arthralgia. FMF is the result of variations in the MEditerraneanFeVer (MEFV) gene, which is located on chromosome 16p13.3, consists of 10 exons and encodes the pyrin (marenostrin) protein. The frequency of MEFV gene variants that cause FMF varies according to ethnic groups, countries and even different regions in the same country. In this study, we aimed to determine the frequency and distribution of MEFV gene alterations that cause Familial Mediterranean fever in southeastern Turkey. \u0000Materials and Methods: A total of 6,660 patients with a prediagnosis of FMF, including 3,495 women and 3,165 men, were included in the study. Fragment analysis was performed to investigate the MEFV gene variations of the patients and the 19 most common variants in the Turkish population were examined. \u0000Results: We found at least one variation in 50.17% (3,341) of our 6,660 patients. In our patients, 108 different genotypes; in Exon 2, 3, 5 and 10 and we identified 16 different variations. We found 2,120 (63.21%) patients heterozygous, 693 (20.74%) compound heterozygotes, 275 (8.23%) homozygous and 261 (7.81%) complex genotypes. The 5 variants with the highest allele frequency are respectively; R202Q (27.84%), M694V (22.83%), E148Q (21.98%), V726A (7.42%), and M680I(G>C) (6.39%). \u0000Conclusion: We identified the most common prevalence of MEFV gene alteration in a large patient group in our region. High R202Q mutation rates were among the remarkable results of this study.","PeriodicalId":19789,"journal":{"name":"Pamukkale Medical Journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88322735","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Relationship between cerebrovascular diseases and human leukocyte antigen subgroups","authors":"Ufuk Cinkir, Eylem Teke, E. Mete","doi":"10.31362/patd.1263788","DOIUrl":"https://doi.org/10.31362/patd.1263788","url":null,"abstract":"Purpose: Ischemic stroke is classified as large artery atherosclerosis, small vessel occlusion (lacunar infarcts), ischemic stroke due to other identified causes, and cryptogenic. The human leukocyte antigen (HLA) complex is a group of genes on chromosome six in humans responsible for encoding cell-surface proteins that regulate the immune system. In this study, HLA’s roles in the pathophysiology of ischemic stroke, especially the lacunar subgroup, are investigated, and their potential mechanisms are presented. \u0000Materials and methods: This study consisted of 49 patients with ischemic stroke and 50 healthy participants. HLA-A, HLA-B, HLA-C, HLA-DQB, and HLA-DRB subgroup genomes were assessed. \u0000Results: A statistically significant difference in the presence of HLA-A, HLA-B, HLA-C, HLA-DQB, and HLA-DRB subgroups was found between the control and patient groups. The presence of HLA-A*02, HLA-A*30, HLA-B*08, HLA-B*15, and HLA-DQB*06 genomes was higher in the patient group than in the control group (p≤0.05). Nevertheless, HLA-DQB*03 and HLA-DRB*11 genomes were found more in the control group than the patient group (p≤0.05) \u0000Conclusion: The results of this study pioneered in scrutinizing HLA alleles in small vascular disease (SVD). HLA-A*01, HLA-A*30, HLA-B*08, HLA-B*15, HLA-DQB*06, HLA-DQB*03 and HLA-DRB*11 are associated with HLA alleles of stroke patients with small vessel occlusion. We attempted to provide objective evidence for whether HLA genomes could act as a discriminative factor between SVD patients and control groups, which might hold considerable promise for future therapies.","PeriodicalId":19789,"journal":{"name":"Pamukkale Medical Journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79754544","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Investigation of the effect of perineural invasion on survival rates in rectal tumors.","authors":"U. Ozgen, U. Sungurtekin, N. Demirkan","doi":"10.31362/patd.1250890","DOIUrl":"https://doi.org/10.31362/patd.1250890","url":null,"abstract":"Purpose: Colorectal cancers compose the third most common cancer group leading to death, with increasing rates in developed countries after lung and breast cancers. Rectal cancers make up about 30% of all colorectal cancers. Although many factors affecting recurrence and survival in rectal cancer have been identified, the stage of the tumor is the most important prognostic factor. However, many additional parameters that can be associated with survival and affect the adjuvant treatment plan have been identified besides the stage. Perineural invasion (PNI) is one of the parameters that can be associated with survival and affect the adjuvant treatment plan in colorectal cancers. The aim of this study is to investigate the effects of various histopathological prognostic factors, including PNI, on disease-free survival, overall survival, and recurrence rates in patients with rectal cancer who underwent surgery. Materials and methods: The clinical records of patients diagnosed with rectal cancer and operated on at the Department of General Surgery, Faculty of Medicine, Pamukkale University between 2008-2014 were reviewed. To investigate the factors affecting disease-free survival, recurrence rates, and overall survival, the presence of PNI, serum CEA levels, cTNM stage, pT stage, pN stage, number of metastatic LNs, tumor budding status, histopathological grades, lymphocyte infiltration, and presence of desmoplasia were evaluated in patients. \u0000Results: A total of 124 patients were included in the study. 42 patients (33.9%) had PNI while 82 patients (66.1%) did not have PNI. Of the 45 patients with recurrence, 26 had PNI while 19 did not have PNI. Of the 79 patients without recurrence, 16 had PNI while 63 did not have PNI. Similarly, PNI was seen more frequently in deaths related to the disease. The 3-year average survival of patients with and without PNI was 55% and 89%, respectively (p","PeriodicalId":19789,"journal":{"name":"Pamukkale Medical Journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72646489","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Closure of the appendix stump with two different suture materials in laparoscopic appendectomy in children","authors":"Osman Uzunlu","doi":"10.31362/patd.1249448","DOIUrl":"https://doi.org/10.31362/patd.1249448","url":null,"abstract":"Purpose: To evaluate the outcomes of the closure of the appendix base using two different suture materials that we used in our clinic with those published in the literature. \u0000 \u0000Materials and methods: The study retrospectively reviews 36 cases of children who underwent laparoscopic appendectomies. The patients were divided into two groups: the Vicryl suture group and the silk suture group. Laboratory results, diagnostic algorithms, surgical techniques, and complications were investigated. \u0000 \u0000Results: \u0000Sixteen (44%) of the cases were male, and twenty (56%) were female. All patients' mean hospital admission time was 2.22±1.6 days (range: 1–7 days). The mean WBC and CRP levels were 14.67±5.8x109/L, 139.3±120 mg/L in the vicryl group and 15.36±6.4x109/L and 86±80 mg/L in the silk group. Small bowel obstruction was observed in nine patients in the vicryl group and six patients in the silk group. Ultrasonography was performed in 31 of the cases, the appendix was visualized in 21 cases (67%).Intravenous contrast-enhanced CT imaging was applied in 25 cases. At laparoscopic exploration, 20 cases were classified as complicated—17 due to perforation, and 3 due to gangrene. All cases were treated with broad-spectrum antibiotics. The mean follow-up period was 43 months (range: 10-117 months); none of the patients experienced intraoperative complications, and only two patients had minor complications in the postoperative period. \u0000 \u0000Conclusion: In all circumstances and regardless of the appendix's diameter, the appendix stump can be securely closed with both silk and vicryl suture material.","PeriodicalId":19789,"journal":{"name":"Pamukkale Medical Journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72884251","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}