与中轴性脊柱炎患者COVID-19发病频率和严重程度相关的因素

M. Pekdiker, M. Kara, Emrah Koç, G. Kimyon
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摘要

目的:慢性疾病患者的COVID-19严重病程引起了对大流行期间风湿性疾病管理的关注,因此我们在本研究中旨在确定与轴性脊柱炎(axSpa)患者中COVID-19频率和严重程度相关的因素。材料-方法:选取在三甲医院定期随访治疗6个月以上的axSpa患者。我们评估了axSpa相关变量(如疾病持续时间、放射学严重程度、治疗和COVID-19结局)之间的关系。结果:共分析833例患者,平均病程109个月;64.5%的患者有强直性脊柱炎,35.5%的患者有非影像学诊断,59.4%的患者接受过生物制剂治疗。COVID-19的频率为23% (n: 192);仅有5例(0.5%)患者有重症监护史。高龄、高血压(HT)和糖尿病(DM)在高分辨率计算机断层扫描(HRCT)患者中更为常见(p:0.02、p:0.01和p
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Factors associated with freqeuncy and severity of COVID-19 in patients with axial spondyloarthritis
Purpose: The severe course of COVID-19 in individuals with chronic diseases has led to concerns in the management of rheumatic diseases during the pandemic therefore we aimed to define the factors associated with the frequency and severity of COVID-19 in patients with axial spondyloarthritis (axSpa) in this study. Materials-Methods: Patients with axSpa who were followed up in three tertiary hospitals and used their treatment regularly for at least six months were included. We assessed the relationship between axSpa associated variables such as disease duration time, radiological severity, treatment and COVID-19 outcomes. Results: A total of 833 patients with a mean disease duration of 109 months were analyzed; 64.5% had ankylosing spondylitis, 35.5% had non-radiographic axSpa diagnosis, and 59.4% of patients were treated with biologic agent . The frequency of COVID-19 was 23% (n: 192); only five pateints (0.5%) had a history of intensive care unit. Advanced age, hypertension (HT), and diabetes mellitus (DM) were found to be significantly more common in those with involvement in high resolution computed tomography (HRCT) (p:0.02, p:0.01, and p
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