Perioperative Medicine最新文献

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The performance of ChatGPT in day surgery and pre-anesthesia risk assessment: a case-control study of 150 simulated patient presentations. ChatGPT 在日间手术和麻醉前风险评估中的表现:对 150 例模拟病人进行的病例对照研究。
IF 2 3区 医学
Perioperative Medicine Pub Date : 2024-11-21 DOI: 10.1186/s13741-024-00469-6
Tingting Cheng, Yu Li, Jiaqiu Gu, Yibo He, Guangbao He, Peipei Zhou, Shuyun Li, Hang Xu, Yang Bao, Xuejun Wang
{"title":"The performance of ChatGPT in day surgery and pre-anesthesia risk assessment: a case-control study of 150 simulated patient presentations.","authors":"Tingting Cheng, Yu Li, Jiaqiu Gu, Yibo He, Guangbao He, Peipei Zhou, Shuyun Li, Hang Xu, Yang Bao, Xuejun Wang","doi":"10.1186/s13741-024-00469-6","DOIUrl":"10.1186/s13741-024-00469-6","url":null,"abstract":"<p><strong>Background: </strong>Day surgery has developed rapidly in China in recent years, although it still faces a shortage of anesthesiologists to handle pre-anesthesia routine before surgery. We hypothesized that ChatGPT may assist anesthesia practitioners in preoperative assessment and answer questions on the concerns of patients. The aims of this study were to examine the ability of ChatGPT to assess preoperative risk and determine its accuracy in answering questions regarding knowledge and management of day surgery anesthesia.</p><p><strong>Methods: </strong>One-hundred fifty patient profiles were generated to simulate day surgery patient presentations that involved complications of varying acuity and severity. The ChatGPT group and the expert group were both required to evaluate the profiles of 150 simulated patients to determine their ASA-PS classification and whether day surgery was recommended. ChatGPT was then asked to answer 131 questions about day surgery anesthesia that represented the most common issues encountered in clinical practice. The performance of ChatGPT was assessed and graded independently by two experienced anesthesiologists.</p><p><strong>Results: </strong>A total of 150 patient profiles were included in the study (75 males [50.0%] and 75 females [50.0%]). There was no difference between the ChatGPT group and the expert group for the ASA-PS classification and assessment of anesthesia risk in the patient profiles (P > 0.05). Regarding recommendation for day surgery in patients with certain comorbidities (ASA ≥ II), the expert group was inclined to require further examination or treatment. In addition, the proportion of conclusions made by ChatGPT was smaller than that of the experts (i.e., ChatGPT n (%) vs. expert n (%): day surgery can be performed, 67 (47.9) vs. 31 (25.4); needs further treatment and evaluation, 56 (37.3) vs. 66 (44.0); and day surgery is not recommended, 18 (12.9) vs. 29 (9.3), P < 0.05). We showed that ChatGPT had extensive knowledge related to day surgery anesthesia (94.0% correct), with most of the points (70%) considered comprehensive. The performance of ChatGPT was also better in the domains of peri-anesthesia concerns, lifestyle, and emotional support.</p><p><strong>Conclusions: </strong>ChatGPT can assist anesthesia practitioners and surgeons by alerting them to the ASA-PS classification and assessing perioperative risk in day surgery patients. ChatGPT can also be trusted to answer questions and concerns related to pre-anesthesia and therefore has the potential to provide important assistance in clinical work.</p>","PeriodicalId":19764,"journal":{"name":"Perioperative Medicine","volume":"13 1","pages":"111"},"PeriodicalIF":2.0,"publicationDate":"2024-11-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11580513/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142688414","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Correction: The impact of preoperative stroke on 1-year mortality and days at home alive after major surgery: an observational cohort study. 更正:术前中风对大手术后 1 年死亡率和居家存活天数的影响:一项观察性队列研究。
IF 2 3区 医学
Perioperative Medicine Pub Date : 2024-11-12 DOI: 10.1186/s13741-024-00467-8
Matilda Widaeus, Alva Cedermark, Max Bell
{"title":"Correction: The impact of preoperative stroke on 1-year mortality and days at home alive after major surgery: an observational cohort study.","authors":"Matilda Widaeus, Alva Cedermark, Max Bell","doi":"10.1186/s13741-024-00467-8","DOIUrl":"10.1186/s13741-024-00467-8","url":null,"abstract":"","PeriodicalId":19764,"journal":{"name":"Perioperative Medicine","volume":"13 1","pages":"109"},"PeriodicalIF":2.0,"publicationDate":"2024-11-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11558809/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142625719","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The use of complementary and alternative medicine among surgical patients: a cross-sectional study. 手术患者使用补充和替代医学:一项横断面研究。
IF 2 3区 医学
Perioperative Medicine Pub Date : 2024-11-12 DOI: 10.1186/s13741-024-00468-7
Abdelkarim Barqawi, Aia Egbaria, Arwa Omari, Noura Abubaji, Faris Abushamma, Amer A Koni, Sa'ed H Zyoud
{"title":"The use of complementary and alternative medicine among surgical patients: a cross-sectional study.","authors":"Abdelkarim Barqawi, Aia Egbaria, Arwa Omari, Noura Abubaji, Faris Abushamma, Amer A Koni, Sa'ed H Zyoud","doi":"10.1186/s13741-024-00468-7","DOIUrl":"10.1186/s13741-024-00468-7","url":null,"abstract":"<p><strong>Background: </strong>The use of complementary and alternative medicine (CAM) has increased substantially around the world; various global studies have documented the use of CAM by surgical patients in the preoperative period, with rates of herbal medications and other nonherbal treatments ranging from 12 to 69%. This study aimed to identify the prevalence of CAM and its patterns of use among surgical patients.</p><p><strong>Methods: </strong>From December 2020 to April 2021, a descriptive cross-sectional study was undertaken in Palestine. A face‒to-face interview questionnaire was used. The participants were asked questions regarding sociodemographics, clinical information, CAM usage, reasons for its use, and opinions on its efficacy.</p><p><strong>Results: </strong>Among the 300 surgical patients who were interviewed in this study, 252 (84.0%) reported that they had ever used CAM, while a total of 122 (48.4%) had used CAM before their surgery, 81.7% of the respondents used herbal methods, and 64.7% of them used nonherbal methods. CAM use among our study population was not linked to specific demographics or other characteristics, except health insurance (p = 0.004). The most commonly used herbs among surgical patients are Salvia officinalis L. (Sage) (84.1%) and Pimpinella anisum L. (Anise) (75.5%). The highest percentage was found among patients with university qualifications (73.2%), who used more than three methods (p < 0.001). In addition, 59.4% of the females used more than three therapies, whereas 45.9% of the males did (p = 0.032).</p><p><strong>Conclusions: </strong>The herbal methods used are common among surgical patients in Palestine and are consistent with the enormous increase in the use of CAM. Therefore, awareness should be raised among the public regarding the risks and benefits of CAM use.</p>","PeriodicalId":19764,"journal":{"name":"Perioperative Medicine","volume":"13 1","pages":"110"},"PeriodicalIF":2.0,"publicationDate":"2024-11-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11559156/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142636089","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Chronic post-surgical pain after total knee arthroplasty: a narrative review. 全膝关节置换术后的慢性术后疼痛:叙述性综述。
IF 2 3区 医学
Perioperative Medicine Pub Date : 2024-11-05 DOI: 10.1186/s13741-024-00466-9
Dan Luo, Zhidong Fan, Wenqin Yin
{"title":"Chronic post-surgical pain after total knee arthroplasty: a narrative review.","authors":"Dan Luo, Zhidong Fan, Wenqin Yin","doi":"10.1186/s13741-024-00466-9","DOIUrl":"10.1186/s13741-024-00466-9","url":null,"abstract":"<p><p>Total knee arthroplasty (TKA) is an efficacious treatment for end-stage knee osteoarthritis, often accompanied by severe postoperative pain. In certain patients, this pain can persist for over 3 months and is referred to as chronic post-surgical pain (CPSP). Postoperative persistent pain has emerged as a significant and noteworthy issue impacting patient quality of life following TKA. The etiology of CPSP after TKA is multifaceted. Peripheral or central sensitizations resulting from inflammatory reactions, nerve injury, and neurobiological mechanisms are the primary mechanisms contributing to chronic persistent pain after TKA. Preoperative, intraoperative, and postoperative factors can induce pain sensitization. Once CPSP occurs after TKA, it significantly hampers patient recovery with challenging treatment options. Currently, among the preventive and therapeutic strategies for chronic pain after TKA, it is widely believed that early comprehensive preventive treatment to prevent acute to chronic pain transition can substantially reduce the incidence of CPSP following TKA. In recent years, studies have investigated perioperative strategies aimed at reducing the occurrence of persistent pain after TKA. This article provides an overview of advancements in understanding the pathogenesis, high-risk factors, and preventive measures for chronic pain following TKA. We hope that this review will guide future research directions on CPSP after TKA while contributing to clinical perioperative pain management.</p>","PeriodicalId":19764,"journal":{"name":"Perioperative Medicine","volume":"13 1","pages":"108"},"PeriodicalIF":2.0,"publicationDate":"2024-11-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11536853/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142583162","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Advances in the multimodal management of perioperative hypothermia: approaches from traditional Chinese and Western medicine. 围术期低体温多模式管理的进展:中西医方法。
IF 2 3区 医学
Perioperative Medicine Pub Date : 2024-10-29 DOI: 10.1186/s13741-024-00465-w
Bin Zhang, Hongmei Zhou, Xiahui Wang, Yeping Zheng, Li Hu
{"title":"Advances in the multimodal management of perioperative hypothermia: approaches from traditional Chinese and Western medicine.","authors":"Bin Zhang, Hongmei Zhou, Xiahui Wang, Yeping Zheng, Li Hu","doi":"10.1186/s13741-024-00465-w","DOIUrl":"10.1186/s13741-024-00465-w","url":null,"abstract":"<p><strong>Purpose: </strong>Maintaining normothermia during the perioperative period is crucial for preventing complications, such as surgical site infections, prolonged hospital stays, and adverse cardiovascular events. This study aimed to elucidate methods of perioperative temperature management by integrating Western and traditional Chinese medicine (TCM) approaches. By combining advanced techniques of Western medicine with holistic and preventative practices of TCM, we aimed to provide a comprehensive strategy for effective perioperative thermal regulation.</p><p><strong>Methods: </strong>And a comprehensive literature review was conducted to analyze the causes of perioperative hypothermia and methods of perioperative temperature management from both Western and traditional Chinese medicine (TCM) perspectives. Special emphasis was placed on evaluating the underlying factors contributing to perioperative hypothermia, as well as the effectiveness, selection criteria, indications, contraindications, adverse reactions, and potential complications associated with various temperature management techniques.</p><p><strong>Results: </strong>Effective prevention and management strategies include preoperative risk assessment, physical warming measures, environmental temperature control, pharmacological interventions, perioperative temperature monitoring, comprehensive warming protocols, and postoperative warming and monitoring. Integrating traditional Chinese medicine provides additional methods to enhance overall effectiveness and patient outcomes. By combining these approaches, healthcare providers can significantly reduce the incidence of inadvertent perioperative hypothermia (IPH) and its associated complications, improving patient safety and recovery.</p><p><strong>Conclusion: </strong>For IPH, a complex and challenging medical condition, both traditional Chinese medicine and Western medicine have established their own theoretical bases and developed corresponding prevention and treatment methods. However, it is important to note that although each of these methods has unique value and potential, they also have specific indications and unavoidable limitations. Therefore, by integrating and combining the complementary strengths and resources of traditional Chinese medicine and Western medicine, we can achieve a more comprehensive and effective prevention of IPH, ultimately improving the health and well-being of those affected.</p>","PeriodicalId":19764,"journal":{"name":"Perioperative Medicine","volume":"13 1","pages":"107"},"PeriodicalIF":2.0,"publicationDate":"2024-10-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11520774/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142546690","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Advancing care of the vulnerable and failing RV in the perioperative period. 推进围手术期对脆弱和衰竭的转录病毒的护理。
IF 2 3区 医学
Perioperative Medicine Pub Date : 2024-10-28 DOI: 10.1186/s13741-024-00463-y
Hayley E Andre, Andrew Shaw
{"title":"Advancing care of the vulnerable and failing RV in the perioperative period.","authors":"Hayley E Andre, Andrew Shaw","doi":"10.1186/s13741-024-00463-y","DOIUrl":"10.1186/s13741-024-00463-y","url":null,"abstract":"","PeriodicalId":19764,"journal":{"name":"Perioperative Medicine","volume":"13 1","pages":"106"},"PeriodicalIF":2.0,"publicationDate":"2024-10-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11520780/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142522636","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparison of intravenous nalbuphine and dexmedetomidine in combination with lidocaine aerosol inhalation in awake direct laryngoscopy: a randomized, double-blind, placebo-controlled trial. 在清醒直接喉镜检查中静脉注射纳布啡和右美托咪定联合吸入利多卡因气雾剂的比较:随机、双盲、安慰剂对照试验。
IF 2 3区 医学
Perioperative Medicine Pub Date : 2024-10-19 DOI: 10.1186/s13741-024-00461-0
Xingxing Li, Cuiyu Xie, Yangyang Wu, Weiwei Zhong, Yao Lu, Yuanhai Li
{"title":"Comparison of intravenous nalbuphine and dexmedetomidine in combination with lidocaine aerosol inhalation in awake direct laryngoscopy: a randomized, double-blind, placebo-controlled trial.","authors":"Xingxing Li, Cuiyu Xie, Yangyang Wu, Weiwei Zhong, Yao Lu, Yuanhai Li","doi":"10.1186/s13741-024-00461-0","DOIUrl":"https://doi.org/10.1186/s13741-024-00461-0","url":null,"abstract":"<p><strong>Background: </strong>The airway should be thoroughly and accurately evaluated before anesthesia induction and endotracheal intubation. Awake direct laryngoscopy (ADL) can provide rapid, accurate, and intuitive airway assessment, especially for suspected difficult airways, and sometimes eliminates the need for fiberoptic intubation in some suspicious difficult airway cases. However, an optimal regimen has not been determined.</p><p><strong>Methods: </strong>In this double-blind, controlled study, prior to ADL, 60 patients scheduled for general anesthesia were randomly allocated to receive 0.75 μg/kg of dexmedetomidine (Dex group, n = 20), 0.15 mg/kg of nalbuphine (Nal group, n = 20), or a placebo (control group, n = 20) intravenously over 10 min. At the same time, all study subjects received nebulized lidocaine for 15 min. The primary outcome was patient tolerance as assessed by a 5-point ADL comfort score, while secondary outcomes included satisfaction, coughing, pain, nausea and vital signs.</p><p><strong>Results: </strong>Patients undergoing ADL in the Nal group had higher tolerance scores than those in the control and Dex groups [4 (3,4) vs. 3 (2,2.75), P < 0.017, and 4 (3,4) vs. 2 (2,2,75), P < 0.001, respectively] and higher satisfaction [7 (6,8) vs. 4 (3,5.75), P < 0.017, and 7 (6,8) vs. 5.5 (5,6), P < 0.001, respectively]. Additionally, the Nal group had significantly fewer adverse events, such as pain and nausea than the control and Dex groups. The sedation score and peripheral oxygen and saturation were significantly higher in the Nal group than in the Dex group, with no difference between the Nal and control groups (P < 0.001, P = 0.159, respectively).</p><p><strong>Conclusions: </strong>Intravenous nalbuphine in combination with lidocaine aerosol inhalation significantly improved patient tolerance and satisfaction while reducing nausea, coughing, pain, sedation, and SpO<sub>2</sub> levels during ADL.</p>","PeriodicalId":19764,"journal":{"name":"Perioperative Medicine","volume":"13 1","pages":"105"},"PeriodicalIF":2.0,"publicationDate":"2024-10-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11490102/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142471874","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Health optimisation for patients with obesity before elective orthopaedic surgery: a qualitative study of professionals' views on restrictive approaches and future practice. 骨科择期手术前肥胖症患者的健康优化:专业人士对限制性方法和未来实践的定性研究。
IF 2 3区 医学
Perioperative Medicine Pub Date : 2024-10-18 DOI: 10.1186/s13741-024-00460-1
Joanna McLaughlin, Ruth Kipping, Hugh McLeod, Andrew Judge, Amanda Owen-Smith
{"title":"Health optimisation for patients with obesity before elective orthopaedic surgery: a qualitative study of professionals' views on restrictive approaches and future practice.","authors":"Joanna McLaughlin, Ruth Kipping, Hugh McLeod, Andrew Judge, Amanda Owen-Smith","doi":"10.1186/s13741-024-00460-1","DOIUrl":"https://doi.org/10.1186/s13741-024-00460-1","url":null,"abstract":"<p><strong>Background: </strong>Preoperative health optimisation for elective surgery entails supporting patients to improve their health in preparation for their treatment and recovery. While there is consensus that this process should address obesity, approaches vary across England. Despite guidance from the National Institute for Health and Care Excellence to the contrary, restrictive approaches with body mass index thresholds for referral to arthroplasty are in use. This qualitative study aimed to investigate the views of professionals on the current use and future implications of these policies.</p><p><strong>Methods: </strong>Semi-structured interviews were conducted with 20 professionals including clinicians, commissioners, policymakers, and health service managers, with experience of developing and/or implementing health optimisation policies for elective arthroplasty. Participants were sampled from areas in England with and without restrictive policies. We undertook thematic analysis of the interview data.</p><p><strong>Results: </strong>Participants described pre-surgical health optimisation as an important trigger for health improvement but identified current resourcing and inadequacies in provision of weight management support as significant barriers to success. Participants expressed concerns about the appropriateness and fairness of including obesity as a determinant to restrict access to surgery. They described short-term financial pressures underlying the use of restrictive body mass index thresholds and a lack of an evidence base, such that policies amounted to rationing and risked exacerbations of health inequalities. The study identified four priorities for improvements to future health optimisation practices: developing and implementing national guidance with flexibility for local variation, initiating patient engagement in primary care with onward integration across all services, improving resourcing to support effective equitable impact, and addressing wider determinants of obesity through societal change.</p><p><strong>Conclusions: </strong>Overall, participants had limited expectations of the impact of health optimisation policies on obesity without additional support, investment, and national guideline implementation. They raised strong concerns over current restrictive approaches. We conclude that addressing concerns around weight management support service availability and impacts on health inequalities is essential for shaping effective health optimisation policies. Future policy direction should support health optimisation to be offered early (ideally in primary care). Health optimisation interventions should be non-restrictive, inclusive, and well-monitored, particularly around equality impact.</p>","PeriodicalId":19764,"journal":{"name":"Perioperative Medicine","volume":"13 1","pages":"104"},"PeriodicalIF":2.0,"publicationDate":"2024-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11488359/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142471889","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Simplified rapid hydration and contrast-associated acute kidney injury among CKD patients stratified by Mehran score: sub-analysis from the TIME Trial. 按 Mehran 评分分层的 CKD 患者中简化快速水化和造影剂相关急性肾损伤:TIME 试验的子分析。
IF 2 3区 医学
Perioperative Medicine Pub Date : 2024-10-14 DOI: 10.1186/s13741-024-00462-z
Yanyan Zhang, Yaokun Liu, Bin Zhang, Fan Yang, Yanjun Gong, Bo Zheng, Yong Huo
{"title":"Simplified rapid hydration and contrast-associated acute kidney injury among CKD patients stratified by Mehran score: sub-analysis from the TIME Trial.","authors":"Yanyan Zhang, Yaokun Liu, Bin Zhang, Fan Yang, Yanjun Gong, Bo Zheng, Yong Huo","doi":"10.1186/s13741-024-00462-z","DOIUrl":"https://doi.org/10.1186/s13741-024-00462-z","url":null,"abstract":"<p><p>Simplified rapid hydration has been proven to be non-inferior to standard hydration in preventing contrast-associated acute kidney injury among chronic kidney disease patients undergoing coronary angiography. The current investigation aimed to further confirm the feasibility and safety of the newly proposed hydration method-simplified rapid hydration (SH) in each risk stratification by Mehran risk score (MRS). Eligible patients (n = 954) randomized to the SH group and standard hydration group were allocated into 2 groups based on MRS: low to moderate-risk and high to very high-risk groups. Primary endpoints were the incidence of contrast-associated acute kidney injury (CA-AKI) and acute heart failure (AHF) (SH vs standard hydration). Secondary endpoints included serum creatinine (Scr), blood urea nitrogen (BUN), cystatin-C (Cys-C), and C-reactive protein (CRP) at 24 h, 48 h, and 72 h after PCI procedure, and the incidence of major adverse cardiac events (MACE). MRS was associated with a higher incidence of CA-AKI (OR = 1.101, 95%CI 1.049-1.156, P < 0.001). In the low to moderate-risk and high to very-high-risk groups, the incidence of CA-AKI in the SH and standard hydration group was 3.3% versus 4.9% (P = 0.5342), 10% versus 12% (P = 0.6392), respectively. Meanwhile, there might be subtle differences in renal function indexes and inflammatory indicators between SH and the control group at different time points. The preventive effect of SH in CA-AKI was similar to standard hydration regardless of MRS-guided risk stratification.</p>","PeriodicalId":19764,"journal":{"name":"Perioperative Medicine","volume":"13 1","pages":"103"},"PeriodicalIF":2.0,"publicationDate":"2024-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11476824/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142471890","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of preoperative oral carbohydrate on the postoperative recovery quality of patients undergoing daytime oral surgery: a randomized controlled trial. 术前口服碳水化合物对日间口腔手术患者术后恢复质量的影响:随机对照试验。
IF 2 3区 医学
Perioperative Medicine Pub Date : 2024-10-14 DOI: 10.1186/s13741-024-00459-8
Weixiang Tang, Gaige Meng, Chen Yang, Yue Sun, Weiwei Zhong, Yao Lu
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