Perioperative Medicine最新文献

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Higher rate of undetected intraoperative damage of latex-free surgical gloves worn by scrub nurses. 消毒护士佩戴的无乳胶手术手套术中未被发现的损伤率较高。
IF 2 3区 医学
Perioperative Medicine Pub Date : 2025-05-06 DOI: 10.1186/s13741-025-00539-3
Leon Euler-Schmidt, Artur Barsumyan, Jan Adriaan Graw, Christian Soost, Yvonne Stephan, Rene Burchard
{"title":"Higher rate of undetected intraoperative damage of latex-free surgical gloves worn by scrub nurses.","authors":"Leon Euler-Schmidt, Artur Barsumyan, Jan Adriaan Graw, Christian Soost, Yvonne Stephan, Rene Burchard","doi":"10.1186/s13741-025-00539-3","DOIUrl":"https://doi.org/10.1186/s13741-025-00539-3","url":null,"abstract":"<p><strong>Background: </strong>Surgical gloves are a medical product and a cornerstone of prevention from surgical site infections and staff injury. This study aimed to investigate the integrity of surgical gloves worn by scrub nurses during selected procedures in both general and trauma surgery. The frequency of defects such as perforations or tears was identified. Furthermore, differences in durability between latex and latex-free gloves were analyzed.</p><p><strong>Methods: </strong>In a 3-month period, a total of 139 surgical glove pairs, both latex and latex-free, used during general or trauma surgery in an academic teaching hospital were collected immediately after procedures. The gloves were subjected to watertightness testing following European norm ISO EN 455:2022 standards. Only gloves visually presumed to be intact were tested for any concealed perforations.</p><p><strong>Results: </strong>The number of perforated glove pairs was similar in both departments (general surgery 25% (n = 14 of 57) vs. trauma surgery 28% (n = 23 of 82), p = 0.79). However, differences in perforation rates by glove models (latex vs. latex-free) were noticed. The likelihood of perforation was increased by a factor of 4.24 with the use of latex-free gloves (χ^2 = 8.48, p = 0.004).</p><p><strong>Conclusions: </strong>Perforation of surgical gloves worn by scrub nurses is a common event during various surgical procedures in general and trauma surgery. In several cases, members of the surgical team do not notice a perforation of a glove. The risk of undetected damage to a surgical glove is significantly higher when latex-free gloves are used. Further research is needed to investigate if the use of a second layer of gloves could reduce this perioperative risk for surgical staff and patients.</p>","PeriodicalId":19764,"journal":{"name":"Perioperative Medicine","volume":"14 1","pages":"51"},"PeriodicalIF":2.0,"publicationDate":"2025-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12054052/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144036383","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Global research trends in perioperative care for diabetic patients: a bibliometric and visualized study. 糖尿病患者围手术期护理的全球研究趋势:文献计量学和可视化研究。
IF 2 3区 医学
Perioperative Medicine Pub Date : 2025-04-30 DOI: 10.1186/s13741-025-00532-w
Jiangru Kang, Xin Chai, Tao Jia, Huiru Hu, Rong Fu, Huang Nie
{"title":"Global research trends in perioperative care for diabetic patients: a bibliometric and visualized study.","authors":"Jiangru Kang, Xin Chai, Tao Jia, Huiru Hu, Rong Fu, Huang Nie","doi":"10.1186/s13741-025-00532-w","DOIUrl":"https://doi.org/10.1186/s13741-025-00532-w","url":null,"abstract":"<p><p>Perioperative management in diabetic patients is important since their postoperative mortality and morbidity are higher than that of non-diabetic patients, which will exacerbate the burden on public health. We selected relevant publications from the WoSCC-SCIE between 2007 and 2024, utilizing VOSviewer and CiteSpace to analyze the collected information and generate knowledge maps. A total of 3167 articles from 792 journals and 83 countries/regions were included for analysis. Overall, there has been a continuous increase in publication volume. From the result of academic collaboration between different countries/regions and institutions, the USA occupies a central position in research strength. A total of 18,101 authors participated in research on \"perioperative management in diabetic patients\" with Dr. Guillermo E. Umpierrez from Emory University School of Medicine being the most productive author. We conclude that perioperative adverse clinical outcomes in diabetic patients and perioperative blood glucose management have consistently been research hotspots in this field. Additionally, continuous glucose monitoring and insulin administration under computer guidance, as well as the use of merging medications are likely to be frontier directions for future research. Research on perioperative care for diabetic patients has been further deepened worldwide, which will be crucial in further improving perioperative care for diabetic patients and enhancing postoperative recovery.</p>","PeriodicalId":19764,"journal":{"name":"Perioperative Medicine","volume":"14 1","pages":"50"},"PeriodicalIF":2.0,"publicationDate":"2025-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12042523/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144022928","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effects of ciprofol on respiratory-related adverse incidence in patients with obesity during painless gastroscopy: a prospective, randomized clinical trial. 环丙酚对无痛胃镜检查中肥胖患者呼吸相关不良事件的影响:一项前瞻性随机临床试验
IF 2 3区 医学
Perioperative Medicine Pub Date : 2025-04-29 DOI: 10.1186/s13741-025-00529-5
Yanjing Zhang, Danru Xie, Feifei Li, Mengjiao Che, Yaoheng Yang, Geng Li, Yiwen Zhang
{"title":"Effects of ciprofol on respiratory-related adverse incidence in patients with obesity during painless gastroscopy: a prospective, randomized clinical trial.","authors":"Yanjing Zhang, Danru Xie, Feifei Li, Mengjiao Che, Yaoheng Yang, Geng Li, Yiwen Zhang","doi":"10.1186/s13741-025-00529-5","DOIUrl":"https://doi.org/10.1186/s13741-025-00529-5","url":null,"abstract":"<p><strong>Background: </strong>Ciprofol is an intravenous anesthetic agent which in low doses produces sedation. It was developed via structural modification of propofol. Ciprofol is claimed to reduce respiratory depression. The object of the present study was to investigate whether or not ciprofol did actually reduce respiratory depression or not in patients with obesity undergoing gastroscopy.</p><p><strong>Methods: </strong>A total of 84 patients with obesity scheduled for gastroscopy were enrolled. The participants were randomly allocated to receive sedation with ciprofol (group C) or propofol (group P). The primary outcome was the incidence of respiratory-related adverse events (AEs), whereas the secondary outcomes were the incidence of further intraoperative and postoperative AEs; procedure and anesthesia success rates; Narcotrend index (NI); induction dosage; procedure time; recovery time; discharge time; and satisfaction ratings from the patients, anesthesiologists, and endoscopists.</p><p><strong>Results: </strong>The incidence of respiratory-related AEs was significantly lower in group C than in group P (17.5% vs. 57.5%; P < 0.001). The occurrence of hypotension and movement during procedural events in group C was markedly reduced compared with that in group P (P = 0.024 and 0.007, respectively). No notable differences were observed in the occurrence of additional AEs or in the success rates of the procedure and anesthesia between the two groups (P > 0.05). The three-point satisfaction levels were comparable between the groups (P > 0.05).</p><p><strong>Conclusions: </strong>0.4 mg/kg of ciprofol provides anesthesia comparable with 2.0 mg/kg of propofol. However, it is related to reduced respiratory-related AEs and hypotension during gastroscopy in patients with obesity; thus, ciprofol is preferred to propofol for anesthesia in obese patients.</p><p><strong>Trial registration: </strong>This study was registered in the Chinese Clinical Trial Registry (KYLS20230625; first registration date: 29/06/2023).</p>","PeriodicalId":19764,"journal":{"name":"Perioperative Medicine","volume":"14 1","pages":"49"},"PeriodicalIF":2.0,"publicationDate":"2025-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12038989/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144064343","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Incidence of prolonged time to tracheal extubation and its associated factors among adult patients undergoing elective surgery at Jimma Medical Center, Jimma, Oromia, Ethiopia, 2024. 2024年在埃塞俄比亚奥罗米亚吉马医疗中心接受择期手术的成年患者气管拔管时间延长的发生率及其相关因素
IF 2 3区 医学
Perioperative Medicine Pub Date : 2025-04-24 DOI: 10.1186/s13741-025-00520-0
Gemechisa Akuma Wayesa, Mitiku Berhanu Wedajo, Wondu Reta Demissie, Admasu Belay Gizaw, Assefa Hika Gudeta, Guteta Gudina Gula
{"title":"Incidence of prolonged time to tracheal extubation and its associated factors among adult patients undergoing elective surgery at Jimma Medical Center, Jimma, Oromia, Ethiopia, 2024.","authors":"Gemechisa Akuma Wayesa, Mitiku Berhanu Wedajo, Wondu Reta Demissie, Admasu Belay Gizaw, Assefa Hika Gudeta, Guteta Gudina Gula","doi":"10.1186/s13741-025-00520-0","DOIUrl":"https://doi.org/10.1186/s13741-025-00520-0","url":null,"abstract":"<p><strong>Purpose: </strong>Extubation refers to removing the breathing tube from the patient's airway after surgery under general anesthesia with tracheal intubation. Extubation procedures typically take less than 15 min, and if they take more, they are prolonged. Whether or not to extubate a patient depends on several factors, including the patient's preoperative status, the type of surgery, anesthetic methods, and expected recovery after the procedure. Thus, the study's objective was to determine the incidence of prolonged extubation and its associated factors among adult patients undergoing surgery at Jimma Medical Center.</p><p><strong>Methods: </strong>A prospective observational study through a consecutive sampling technique was conducted. Ethical clearance and approval were obtained from the institutional review board of Jimma University. Data on the extubation time and possible associated factors for a prolonged extubation time were collected using a data collection checklist. After being entered into EpiData 4.6 and exported into SPSS 25, descriptive analyses and logistic regression were carried out. In multivariate variables, p ≤ 0.05 was declared as statistical significance.</p><p><strong>Result: </strong>Three-hundred eight adult patients were enrolled in the current study. Of these, the incidence of prolonged extubation was 24.7% (95% CI [20.0-29.9]). The identified associated factors were age ≥ 55 years (AOR = 5.7, 95% CI [2.62, 12.69], p ≤ 001); ASAPS > II (AOR = 4.27, 95% CI [1.59, 11.45], p = 004); BMI ≥ 30 kg/m<sup>2</sup> (AOR = 6.6, 95% CI [2.37, 18.36], p ≤ 001); the use of benzodiazepine (AOR = 3.43, 95% CI [1.42, 8.25], p = 0.006); using of isoflurane (AOR = 0.35, 95% CI [0.15, 0.78], p = 0.011); prone position (AOR = 4.68, 95% CI [1.56, 14.07], p = 0.006); extubation in afternoon (AOR = 2.69, 95% CI [1.26, 5.74]; p = 0.011); and duration of surgery ≥ 210 min (AOR = 5.2, 95% CI [2.32, 11.72], p ≤ 0.001).</p><p><strong>Conclusions: </strong>The study found that prolonged time to extubation occurred in one-fourth of the patients. The independent factors statistically associated with prolonged extubation were older ages, higher ASA class, obesity (≥ 30 kg/m<sup>2</sup>), the use of benzodiazepine, halothane for maintenance, prone position, extubation in the afternoon, and longer procedures (≥ 210 min).</p>","PeriodicalId":19764,"journal":{"name":"Perioperative Medicine","volume":"14 1","pages":"48"},"PeriodicalIF":2.0,"publicationDate":"2025-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12020074/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144005084","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The impact of frailty on functional recovery after cardiac surgery-a case control study. 心脏手术后虚弱对功能恢复的影响——一项病例对照研究。
IF 2 3区 医学
Perioperative Medicine Pub Date : 2025-04-23 DOI: 10.1186/s13741-025-00526-8
M Abdelmonem, M Elsayed, D Awadallah, O Don, R H Bennett, O G Mackay, S Pookayil, C Archer, M Mahgoub, M J Bennett
{"title":"The impact of frailty on functional recovery after cardiac surgery-a case control study.","authors":"M Abdelmonem, M Elsayed, D Awadallah, O Don, R H Bennett, O G Mackay, S Pookayil, C Archer, M Mahgoub, M J Bennett","doi":"10.1186/s13741-025-00526-8","DOIUrl":"https://doi.org/10.1186/s13741-025-00526-8","url":null,"abstract":"<p><strong>Background: </strong>Good functional recovery after cardiac surgery can be reported as 'days alive and out of hospital' in the first 30 days after a procedure (DAOH<sub>30</sub>) and 'days at home' in the first year (DAH<sub>365</sub>), which integrate several clinically important outcomes, including death, hospital length of stay, quality of recovery and hospital readmission. They depend on the preservation or early recovery of physiological and functional capacity, both of which may be lost in patients living with frailty.</p><p><strong>Case presentation: </strong>We measured frailty with a multidimensional approach, incorporating 30 variables spanning comorbidity, sensory, cognitive, psychosocial, disability and pharmaceutical domains, which together make up the Patient Frailty Index (pFI). We further explored the impact of socioeconomic factors on functional recovery using the Welsh Index of Multiple Deprivation (WIMD). The outcome measures included duration of level 3 and level 2 care, duration of hospital stay, readmission and both short- and longer-term mortality. A total of 669 patients were included in the final analysis. A total of 224 (33.5%) of the patients were 'frail'. They were more likely to have chronic obstructive pulmonary disease, heart failure and diabetes and to be in the lowest decile for deprivation. Frailty was not associated with either sex or advanced age. Patients deemed to be 'frail' had a longer stay in intensive care, required level 3 cardiovascular and respiratory support for longer and stayed longer in the hospital. They spent fewer days at home in the first 30 days, largely due to days requiring advanced cardiovascular support, and fewer days at home in the first year, with most days lost to patients who died in the first year following their surgery. A moderation analysis examined whether the WIMD modified the effect of frailty on recovery after cardiac surgery. The interaction term, after confirming there were no collinearity concerns, was not significant, either for DAOH<sub>30</sub> or DAH<sub>365</sub>, indicating no evidence of moderation.</p><p><strong>Conclusions: </strong>Short- and medium-term measures of good functional recovery were lower in 'frail' patients, and longer-term survival was also significantly reduced. An accumulation of deficits assessment of frailty, incorporating multiple domains, builds a more accurate picture of increasing vulnerability and can be acquired from patients' electronic health records. In a surgical population that is increasingly comorbid, these findings should inform decisions on preoperative priority setting, prehabilitation, postoperative resources and discharge planning.</p>","PeriodicalId":19764,"journal":{"name":"Perioperative Medicine","volume":"14 1","pages":"46"},"PeriodicalIF":2.0,"publicationDate":"2025-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12016124/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144011643","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Global trends in artificial intelligence research in anesthesia from 2000 to 2023: a bibliometric analysis. 从2000年到2023年麻醉人工智能研究的全球趋势:文献计量分析。
IF 2 3区 医学
Perioperative Medicine Pub Date : 2025-04-23 DOI: 10.1186/s13741-025-00531-x
Yi Ou, Xiaoyi Hu, Cong Luo, Yajun Li
{"title":"Global trends in artificial intelligence research in anesthesia from 2000 to 2023: a bibliometric analysis.","authors":"Yi Ou, Xiaoyi Hu, Cong Luo, Yajun Li","doi":"10.1186/s13741-025-00531-x","DOIUrl":"https://doi.org/10.1186/s13741-025-00531-x","url":null,"abstract":"<p><strong>Background: </strong>Interest in artificial intelligence (AI) research in anesthesia is growing rapidly. However, there is a lack of bibliometric analysis to measure and analyze global scientific publications in this field. The aim of this study was to identify the hotspots and trends in AI research in anesthesia through bibliometric analysis.</p><p><strong>Methods: </strong>English articles and reviews published from 2000 to 2023 were retrieved from the Web of Science Core Collection (WoSCC) database. The extracted data were summarized and analyzed using Microsoft Excel, and bibliometric analysis were conducted with VOSviewer software.</p><p><strong>Results: </strong>AI research literature in anesthesia has exhibited rapid growth in recent years. The United States leads in the number of publications and citations, with Stanford University as the most prolific institution. Hyung-Chul Lee is the author with the highest number of publications. The journal Anesthesiology is highly recognized and authoritative in this field. Recent keywords include \"musculoskeletal pain\", \"precision medicine\", \"stratification\", \"images\", \"mean arterial pressure\", \" enhanced recovery after surgery\", \"frailty\", \"telehealth\", \"postoperative delirium\" and \"postoperative mortality\" indicating hot topics in AI research in anesthesia.</p><p><strong>Conclusions: </strong>Publications on AI research in the field of anesthesia have experienced rapid growth over the past two decades and are likely to continue increasing. Research areas such as depth of anesthesia (DOA) and drug infusion (including electroencephalography and deep learning), perioperative risk assessment and prediction (covering mean arterial pressure, frailty, postoperative delirium, and mortality), image classification and recognition (for applications such as ultrasound-guided nerve blocks, vascular access, and difficult airway assessment), and perioperative pain management (particularly musculoskeletal pain) have garnered significant attention. Additionally, topics such as precision medicine, enhanced recovery after surgery, and telehealth are emerging as new hotspots and future directions in this field.</p>","PeriodicalId":19764,"journal":{"name":"Perioperative Medicine","volume":"14 1","pages":"47"},"PeriodicalIF":2.0,"publicationDate":"2025-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12016147/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144037603","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Clinical value of NT-proBNP, MPO, and NLR combined with echocardiography in prediction of malignant arrhythmia in elderly patients with valvular heart disease. NT-proBNP、MPO、NLR联合超声心动图预测老年瓣瓣膜病患者恶性心律失常的临床价值
IF 2 3区 医学
Perioperative Medicine Pub Date : 2025-04-22 DOI: 10.1186/s13741-025-00527-7
Jianping Liu, Apei Zhou, Meiduan Zheng, Ling Wang, Ping Zeng
{"title":"Clinical value of NT-proBNP, MPO, and NLR combined with echocardiography in prediction of malignant arrhythmia in elderly patients with valvular heart disease.","authors":"Jianping Liu, Apei Zhou, Meiduan Zheng, Ling Wang, Ping Zeng","doi":"10.1186/s13741-025-00527-7","DOIUrl":"https://doi.org/10.1186/s13741-025-00527-7","url":null,"abstract":"<p><strong>Objective: </strong>We aimed to probe the clinical value of N-terminus pro-brain natriuretic peptide (NT-proBNP), myeloperoxidase (MPO), and neutrophil lymphocyte ratio (NLR) combined with echocardiography in the prediction of malignant arrhythmias (MA) in elderly patients with valvular heart disease (VHD).</p><p><strong>Methods: </strong>MPO, NT-proBNP, and NLR were detected in blood samples. After 1 year of follow-up, receiver operating characteristic curves were analyzed to determine the clinical value of NT-proBNP, MPO, NLR, and echocardiography for predicting MA in patients with VHD.</p><p><strong>Results: </strong>MPO, NT-proBNP, and NLR were higher in the VHD group. MPO, NT-proBNP, and NLR were higher with severe cardiac dysfunction. MPO, NT-proBNP, NLR, and LVESV in the MA group were higher. NT-proBNP was an independent factor influencing the occurrence of MA in elderly patients with VHD. The AUC for predicting MA in elderly patients with VHD using NT-proBNP, MPO, NLR, and echocardiography were 0.782 (sensitivity 61.50%, specificity 94.60%, 95% CI 0.630-0.934), 0.759 (sensitivity 69.20%, specificity 81.10%, 95% CI 0.579-0.938), 0.736 (sensitivity 76.90%, specificity 64.90%, 95% CI 0.562-0.910), and 0.782 (sensitivity 76.90%, specificity 75.70%, 95% CI 0.646-0.918), respectively. The AUC for the combined prediction using NT-proBNP, MPO, NLR, and echocardiography was 0.913 (sensitivity 76.90%, specificity 94.60%, 95% CI 0.820-1.000), higher than that of each parameter alone (P < 0.05).</p><p><strong>Conclusion: </strong>The combination of NT-proBNP, MPO, NLR, and echocardiography has a predictive value in detecting MA in elderly VHD patients.</p>","PeriodicalId":19764,"journal":{"name":"Perioperative Medicine","volume":"14 1","pages":"44"},"PeriodicalIF":2.0,"publicationDate":"2025-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12016093/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144064342","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Association between the preoperative N-terminal pro-B-type natriuretic peptide and acute kidney injury in gastrointestinal surgery patients managed with enhanced recovery strategy: a retrospective cohort study. 一项回顾性队列研究:采用增强恢复策略的胃肠手术患者术前n端前b型利钠肽与急性肾损伤的关系
IF 2 3区 医学
Perioperative Medicine Pub Date : 2025-04-22 DOI: 10.1186/s13741-025-00528-6
Zefei Zhang, Ziyu Zheng, Huang Nie, Hailong Dong, Chong Lei
{"title":"Association between the preoperative N-terminal pro-B-type natriuretic peptide and acute kidney injury in gastrointestinal surgery patients managed with enhanced recovery strategy: a retrospective cohort study.","authors":"Zefei Zhang, Ziyu Zheng, Huang Nie, Hailong Dong, Chong Lei","doi":"10.1186/s13741-025-00528-6","DOIUrl":"https://doi.org/10.1186/s13741-025-00528-6","url":null,"abstract":"<p><p>Importance Previous evidence has indicated that N-terminal pro-B-type natriuretic peptide (NT-proBNP) is associated with postoperative acute kidney injury (AKI). However, the association between preoperative NT-proBNP level and postoperative AKI in surgeries managed with enhanced recovery after surgery (ERAS) strategy requires further clarification.Objective To explore the association between preoperative NT-proBNP and the incidence of postoperative AKI in patients who underwent gastrointestinal surgeries and managed with ERAS strategy.Design A retrospective cohort study.Setting A review of documented cases of elective gastrointestinal surgeries managed with ERAS strategy occurred at Xijing Hospital from 01 May 2017 to 30 June 2022.Participants A total of 629 patients aged 18 years or older who were scheduled for elective gastrointestinal surgeries and subjected to the ERAS strategy with preoperative NT-proBNP and creatinine measurements were included in the analysis.Exposure Preoperative serum concentrations of NT-proBNP.Main outcomes and measures The primary outcome was the incidence of postoperative AKI. Preoperative NT-proBNP was divided into high- or low-level groups based on the median (165 pg/ml). Logistic regression was used to explore the association between increased preoperative NT-proBNP level and risk of AKI.Results After screening 1932 case records, 629 cases were included in the final analyses. The average age was 63.5 (15.3) years old and 197 (31.3%) of them were female. Among them, 112 (17.8%) developed postoperative AKI. The incidence of AKI was 21% in the high NT-proBNP group, and 14.6% in the low NT-proBNP group. Patients with higher preoperative NT-proBNP levels (≥ 165 pg/mL) have significant higher risk of postoperative AKI as compared to those in the lower group (adjusted OR 1.75; 95% CI 1.12 to 2.73).Conclusions and relevance Increased preoperative NT-proBNP is associated with an elevated risk of postoperative AKI in patients who underwent gastrointestinal surgery and managed with ERAS strategy.Trial registry number Clinical trial registry number: NCT06145347.</p>","PeriodicalId":19764,"journal":{"name":"Perioperative Medicine","volume":"14 1","pages":"45"},"PeriodicalIF":2.0,"publicationDate":"2025-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12016297/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144022922","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Measures to accelerate recovery from stage III tuberculous empyema: tuberculous empyema surgical and recovery methods. 加速III期结核性脓肿恢复的措施:结核性脓肿手术和恢复方法。
IF 2 3区 医学
Perioperative Medicine Pub Date : 2025-04-17 DOI: 10.1186/s13741-025-00530-y
Jiakun Liu, Yanchao Luan, Qingsong Han, Wei Zhao
{"title":"Measures to accelerate recovery from stage III tuberculous empyema: tuberculous empyema surgical and recovery methods.","authors":"Jiakun Liu, Yanchao Luan, Qingsong Han, Wei Zhao","doi":"10.1186/s13741-025-00530-y","DOIUrl":"https://doi.org/10.1186/s13741-025-00530-y","url":null,"abstract":"<p><strong>Objectives: </strong>To evaluate the effects of video-assisted thoracoscopic decortication (VATD) and enhanced recovery after surgery (ERAS) in patients with stage III tuberculous empyema.</p><p><strong>Methods: </strong>The 360 participants were divided into four groups according to the treatment received: thoracotomy decortication (TD) + traditional recovery procedures (TRP), TD + ERAS, VATD + TRP, and VATD + ERAS. We evaluated the effects of the treatment modalities on various intraoperative and postoperative outcome measures. Multivariate analysis was then performed to identify risk factors associated with increased postoperative the length of hospital (LOS).</p><p><strong>Results: </strong>There were significant differences between the TD and VATS groups in terms of the duration of surgery, intraoperative blood loss, postoperative drainage, postoperative erythrocyte sedimentation rate (ESR), LOS, and pain levels. The use of ERAS also showed significant effects in certain outcome measures. There were no significant differences in the incidence of postoperative complications among the groups. The use of VATD and ERAS procedures, and preoperative antituberculosis therapy, was inversely associated with the LOS.</p><p><strong>Conclusions: </strong>Implementation of VATD and ERAS procedures in patients with stage III tuberculous empyema can significantly reduce the LOS and improve patient outcomes in a safe and effective manner.</p>","PeriodicalId":19764,"journal":{"name":"Perioperative Medicine","volume":"14 1","pages":"43"},"PeriodicalIF":2.0,"publicationDate":"2025-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12004697/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144031530","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Impact of prolonged cardiopulmonary bypass on gastrointestinal complications in cardiac surgery: a retrospective cohort study. 心脏手术中延长体外循环对胃肠道并发症的影响:一项回顾性队列研究。
IF 2 3区 医学
Perioperative Medicine Pub Date : 2025-04-15 DOI: 10.1186/s13741-025-00524-w
Xiaofang Yang, Ning Lu, Luxi Yang, Boxia Li, Wenjun Zhou, Yuanmin Li, Bing Song, Jinqiu Yuan, Wenbo Meng
{"title":"Impact of prolonged cardiopulmonary bypass on gastrointestinal complications in cardiac surgery: a retrospective cohort study.","authors":"Xiaofang Yang, Ning Lu, Luxi Yang, Boxia Li, Wenjun Zhou, Yuanmin Li, Bing Song, Jinqiu Yuan, Wenbo Meng","doi":"10.1186/s13741-025-00524-w","DOIUrl":"https://doi.org/10.1186/s13741-025-00524-w","url":null,"abstract":"<p><strong>Background: </strong>Gastrointestinal complications (GICs) following cardiac surgery with cardiopulmonary bypass (CPB) significantly impact postoperative recovery and clinical outcomes.</p><p><strong>Methods: </strong>This single-center, retrospective cohort study evaluated the incidence, risk factors, and outcomes of GICs in patients undergoing cardiac surgery with CPB between January 2018 and December 2023. Patients were stratified by CPB duration (≥ 120 min vs. < 120 min). Propensity Score Matching (PSM) in a 1:2 ratio was used to control for baseline confounders. The primary outcome was the occurrence of GICs within 30 days post-surgery.</p><p><strong>Results: </strong>Among 1444 patients, 686 had prolonged CPB duration, with an overall GICs incidence of 8.59% (124/1444). After PSM, the prolonged CPB group exhibited a significantly higher incidence of GICs compared to the normal CPB group (8.09% vs. 4.31%, p = 0.041). Multivariate logistic regression identified prolonged CPB duration (≥ 120 min; OR, 1.86; 95% CI, 1.06-3.26, p = 0.029), hypertension (OR 1.86; 95% CI, 1.01-3.44; p = 0.049), left ventricular ejection fraction (LVEF; OR, 0.92; 95% CI, 0.88-0.96; p < 0.001), and aortic surgery (OR, 2.72; 95% CI, 1.20-6.19; p = 0.017) as independent risk factors for GICs. Additionally, prolonged ventilator time and higher in-hospital costs were more prevalent in the prolonged CPB group.</p><p><strong>Conclusions: </strong>Prolonged CPB (≥ 120 min), hypertension, LVEF, and aortic surgery are significant risk factors for GICs following cardiac surgery with CPB. Early identification of high-risk patients may facilitate timely intervention, reduce complications, and improve postoperative recovery outcomes.</p><p><strong>Trial registration: </strong>ClinicalTrials.gov: NCT06697405.</p>","PeriodicalId":19764,"journal":{"name":"Perioperative Medicine","volume":"14 1","pages":"42"},"PeriodicalIF":2.0,"publicationDate":"2025-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11998269/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144022840","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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