Pain MedicinePub Date : 2025-09-01DOI: 10.1093/pm/pnaf047
James S Cho, Alanah Grisham, Annette Wang, Rafael Vazquez, Charles Kelly, Pascal Scemama, David Hao
{"title":"Focused anatomic review: ultrasound-guided peripheral nerve stimulation of the femoral, iliohypogastric, and ilioinguinal nerves.","authors":"James S Cho, Alanah Grisham, Annette Wang, Rafael Vazquez, Charles Kelly, Pascal Scemama, David Hao","doi":"10.1093/pm/pnaf047","DOIUrl":"10.1093/pm/pnaf047","url":null,"abstract":"","PeriodicalId":19744,"journal":{"name":"Pain Medicine","volume":" ","pages":"591-595"},"PeriodicalIF":3.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143974922","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pain MedicinePub Date : 2025-09-01DOI: 10.1093/pm/pnaf065
{"title":"Corrigendum to: The implementation of a pain navigator program in the department of Veterans Affairs' (VA) health care systems: a cluster randomized pragmatic clinical trial.","authors":"","doi":"10.1093/pm/pnaf065","DOIUrl":"10.1093/pm/pnaf065","url":null,"abstract":"","PeriodicalId":19744,"journal":{"name":"Pain Medicine","volume":" ","pages":"616"},"PeriodicalIF":3.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12405745/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144234717","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pain MedicinePub Date : 2025-09-01DOI: 10.1093/pm/pnaf045
Robert W Hurley, Alexandra M Coffield, Spencer W Faircloth, Jae C Yong, Meredith C B Adams
{"title":"Cost disparities between pain and opioid use disorder formulations of buprenorphine in US health care system: a cross-sectional analysis.","authors":"Robert W Hurley, Alexandra M Coffield, Spencer W Faircloth, Jae C Yong, Meredith C B Adams","doi":"10.1093/pm/pnaf045","DOIUrl":"10.1093/pm/pnaf045","url":null,"abstract":"","PeriodicalId":19744,"journal":{"name":"Pain Medicine","volume":" ","pages":"611-614"},"PeriodicalIF":3.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12405749/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144024210","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pain MedicinePub Date : 2025-09-01DOI: 10.1093/pm/pnaf119
Min Cao, Jialu Xu, Lan Zhu
{"title":"Construction and validation of medication deviation in cancer pain patients with oral opioid formulations during hospital-to-home transition.","authors":"Min Cao, Jialu Xu, Lan Zhu","doi":"10.1093/pm/pnaf119","DOIUrl":"https://doi.org/10.1093/pm/pnaf119","url":null,"abstract":"<p><strong>Objective: </strong>The transition from hospital to home is a high-risk period for medication errors, particularly in patients receiving opioids. We constructed and validated a Medication Deviation Risk Prediction Model (MDRP) in cancer pain patients during hospital-to-home transition.</p><p><strong>Methods: </strong>The medication deviation assessment table was constructed to determine whether there was a medication deviation in the MDRP modeling group. Univariate analysis and logistic regression were used to analyze influencing factors. The model's goodness of predictive effect was tested using Hosmer-Lemeshow (H-L) and Receiver Operating Characteristic (ROC) curves. External validation was performed using the same methods, and developed a simple risk scoring scale.</p><p><strong>Results: </strong>In the modelling group, 33.33% (51/153) had medication deviation, while 66.67% (102/153) had no medication deviation. BPI score, number of comorbidities, presence of long-term caregivers, medication adherence, and presence of anxiety/depression were the five independent influencing factors in the construction of MDRP (P < 0.05). The H-L test yielded p = 0.402, and the area under the ROC curves (AUC) was 0.875, with sensitivity at 0.765 and specificity at 0.882. The validation group results were consistent with the modeling group. a simple risk scoring scale was developed with a total score of 6, a cutoff value of 4, and an AUC of 0.886. The predictive accuracy of the scoring scale was 86.90%.</p><p><strong>Conclusion: </strong>The MDRP of cancer pain patients had high sensitivity and specificity. The simple risk scoring scale was convenient and practical in clinical practice.</p>","PeriodicalId":19744,"journal":{"name":"Pain Medicine","volume":" ","pages":""},"PeriodicalIF":3.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144964119","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pain MedicinePub Date : 2025-09-01DOI: 10.1093/pm/pnaf046
Byron Schneider, Jordan A Buttner, W Evan Rivers, Ameet Nagpal, Jaymin Patel, Patricia Zheng, Zachary L McCormick, David J Kennedy, Reza Ehsanian
{"title":"Discrepancies of calculated percentage pain reduction versus patient reported percentage perceived reduction in pain intensity after axial spine medial branch block.","authors":"Byron Schneider, Jordan A Buttner, W Evan Rivers, Ameet Nagpal, Jaymin Patel, Patricia Zheng, Zachary L McCormick, David J Kennedy, Reza Ehsanian","doi":"10.1093/pm/pnaf046","DOIUrl":"10.1093/pm/pnaf046","url":null,"abstract":"<p><strong>Objective: </strong>This study compares 2 pain intensity metrics, calculated percentage pain reduction (CPPR) and patient-reported percentage pain reduction (PRPPR), in patients undergoing medial branch nerve blocks (MBB) to determine their comparability and agreement.</p><p><strong>Methods: </strong>A retrospective review of prospectively enrolled consecutive MBB patients with axial spine pain from multiple centers. Data were collected via self-report pain diaries and analyzed using linear regression models, concordance correlation coefficients (CCC), and Bland-Altman plots.</p><p><strong>Results: </strong>One hundred and fifty pain diaries yielded 1182/1350 (88%) valid comparisons between CPPR and PRPPR. The CCC was lowest immediately and at 0.5 hours post-injection (0.44 and 0.47) and ranged from 0.58 to 0.62 at later times. Precision, measuring correlation, was poor, while accuracy, measuring the degree of deviation from perfect agreement, was greater than 0.90. Bland-Altman plots showed PRPPR indicated greater pain relief than CPPR at all times, with bias decreasing as pain relief increased. Agreement was higher at 0% and 100% improvement compared to 50% on Bland-Altman plots.</p><p><strong>Conclusions: </strong>The CCC ranged from 0.44 to 0.62 between PRPPR and CPPR in patients with chronic axial pain undergoing diagnostic MBB. PRPPR scores showed greater pain relief than CPPR scores, especially over time. Agreement was higher at extremes of pain relief, while partial average pain relief demonstrated less agreement. Clinicians should therefore not assume equivalence between CPPR and PRPPR. More importantly, there is significant variability in how a patient is categorized for MBB success depending on the measure employed.</p>","PeriodicalId":19744,"journal":{"name":"Pain Medicine","volume":" ","pages":"527-537"},"PeriodicalIF":3.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144041020","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pain MedicinePub Date : 2025-09-01DOI: 10.1093/pm/pnaf029
Candice L Collins, Karen England, Saranrat W Conrad, Hannah Day, Ermias Tilahun, Gerald Dal Pan, Tamra Meyer
{"title":"Patient-reported duration of opioid analgesic use after discharge from surgical procedures or other types of acute pain: a scoping review.","authors":"Candice L Collins, Karen England, Saranrat W Conrad, Hannah Day, Ermias Tilahun, Gerald Dal Pan, Tamra Meyer","doi":"10.1093/pm/pnaf029","DOIUrl":"10.1093/pm/pnaf029","url":null,"abstract":"<p><strong>Objective: </strong>To conduct a scoping literature review of patient-reported duration and amount of post-discharge or outpatient opioid analgesic use for acute pain.</p><p><strong>Design: </strong>We searched PubMed for studies, published from January 1, 2017, through June 27, 2022, describing patient-reported opioid analgesic use after discharge from surgical procedures or other types of acute pain.</p><p><strong>Outcomes: </strong>We abstracted and standardized information on the duration (days) and amount of use (converted to 5 mg oxycodone tablets using morphine milligram equivalents).</p><p><strong>Results: </strong>From 86 studies, we found that duration and amount of opioid analgesic use varied greatly across and within surgical procedures. For some minimally invasive procedures, a minority of patients reported using no opioids. Various factors were associated with the duration or amount of opioid analgesic use, such as preoperative opioid use. Gaps and limitations in the literature include: few studies assessing non-surgical acute pain and certain specific surgical procedures, and methodologic differences limiting comparability across studies.</p><p><strong>Conclusions: </strong>Patient-reported data of opioid analgesic use to manage various types of acute pain helps inform opioid prescribing guidelines, but gaps across the existing literature must be carefully considered. We conclude that (1) there is wide variation in patient-reported opioid analgesic use across types of surgical procedures as well as within surgical procedures, potentially driven by patient, surgical, and institutional factors and (2) there continue to be unused tablets prescribed for many types of postsurgical pain, especially for minimally invasive procedures. In part, this work informed the April 2023 Food and Drug Administration's opioid analgesic labeling changes.</p>","PeriodicalId":19744,"journal":{"name":"Pain Medicine","volume":" ","pages":"503-514"},"PeriodicalIF":3.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143730869","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pain MedicinePub Date : 2025-09-01DOI: 10.1093/pm/pnaf053
Bishaal Tej Gurung, Louisa Picco, Grant Russell, Christopher Pearce, Suzanne Nielsen, Ting Xia
{"title":"Understanding the first prescription: clinical and demographic drivers of strong opioid use in primary care.","authors":"Bishaal Tej Gurung, Louisa Picco, Grant Russell, Christopher Pearce, Suzanne Nielsen, Ting Xia","doi":"10.1093/pm/pnaf053","DOIUrl":"10.1093/pm/pnaf053","url":null,"abstract":"<p><strong>Aim: </strong>To evaluate the demographic and clinical factors that influence the initiation of weak versus strong opioids among opioid-naïve patients in Australian primary care settings.</p><p><strong>Methods: </strong>This retrospective cohort study focused on opioid-naïve patients, defined as those receiving an eligible opioid prescription with no prior opioid prescriptions in the prior year. The study used general practice data extracted in partnership with Primary Health Networks via the POpulation Level Analysis and Reporting (POLAR) platform. Opioid prescriptions at the time of initiation were categorized as weak or strong. We used multivariate probit model analysis to identify the demographic and clinical factors associated with type of opioid at initiation of prescribing.</p><p><strong>Results: </strong>We identified 415 098 opioid-naïve patients in primary care between January 1, 2018, and July 31, 2023, with 17% initiated on strong opioids. The probability of initiation with a strong opioid increased in patients who were more than 80 years of age by 25.0% (95% CI: 0.244 to 0.257) compared with patients who were 20-29 years of age. Patients with diagnoses of pain related to injury procedures (9.7% increase; 95% CI: 0.093 to 0.101) or with prior antipsychotic prescriptions (6.2% increase; 95% CI: 0.055 to 0.067) had higher probabilities of being prescribed strong opioids at initiation than did those without these conditions.</p><p><strong>Conclusion: </strong>One in 6 patients initiated on opioids in primary care was prescribed a strong opioid. This study highlights key factors associated with initiation of strong opioids among opioid-naïve patients. Further assessment of clinical suitability and outcomes associated with strong opioid prescribing can inform our understanding of opioid use in primary care.</p>","PeriodicalId":19744,"journal":{"name":"Pain Medicine","volume":" ","pages":"583-590"},"PeriodicalIF":3.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12405760/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143975444","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pain MedicinePub Date : 2025-09-01DOI: 10.1093/pm/pnaf098
Samantha M Meints, Jolin Yamin
{"title":"Editorial: Are they being difficult or just having a difficult time?","authors":"Samantha M Meints, Jolin Yamin","doi":"10.1093/pm/pnaf098","DOIUrl":"10.1093/pm/pnaf098","url":null,"abstract":"","PeriodicalId":19744,"journal":{"name":"Pain Medicine","volume":" ","pages":"501-502"},"PeriodicalIF":3.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12405747/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144699215","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pain MedicinePub Date : 2025-09-01DOI: 10.1093/pm/pnaf048
Jaira Ehlers, Barbara Regina França, Graziele Borges Bueno, Jessica S Vebber, Rogério Boff Borges, Iraci L S Torres, Felipe Fregni, Wolnei Caumo
{"title":"Cross-cultural validation of the revised graded chronic pain scale in Brazilian Portuguese: advancing health and disability assessment across cultures.","authors":"Jaira Ehlers, Barbara Regina França, Graziele Borges Bueno, Jessica S Vebber, Rogério Boff Borges, Iraci L S Torres, Felipe Fregni, Wolnei Caumo","doi":"10.1093/pm/pnaf048","DOIUrl":"10.1093/pm/pnaf048","url":null,"abstract":"","PeriodicalId":19744,"journal":{"name":"Pain Medicine","volume":" ","pages":"603-606"},"PeriodicalIF":3.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144036894","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pain MedicinePub Date : 2025-09-01DOI: 10.1093/pm/pnaf035
Jennifer Kawi, Chao Hsing Yeh, Nada Lukkahatai, Hulin Wu, Natalia E Morone, Ronald Glick, Elizabeth A Schlenk, Claudia Campbell, Johannes Thrul, Xinran Huang, Hongyu Wang, Hejingzi Monica Jia, Paul Christo, Constance Johnson
{"title":"Auricular point acupressure for older adults with chronic low back pain: a randomized controlled trial.","authors":"Jennifer Kawi, Chao Hsing Yeh, Nada Lukkahatai, Hulin Wu, Natalia E Morone, Ronald Glick, Elizabeth A Schlenk, Claudia Campbell, Johannes Thrul, Xinran Huang, Hongyu Wang, Hejingzi Monica Jia, Paul Christo, Constance Johnson","doi":"10.1093/pm/pnaf035","DOIUrl":"10.1093/pm/pnaf035","url":null,"abstract":"<p><strong>Objective: </strong>Efficacious modalities are limited in chronic low back pain (cLBP). We determined the efficacy of auricular point acupressure (APA) in older adults with cLBP.</p><p><strong>Design: </strong>3-arm randomized controlled trial.</p><p><strong>Setting: </strong>Baltimore, Maryland.</p><p><strong>Participants: </strong>Participants, ≥60 years with cLBP, were randomized (1:1:1) to APA with ear points targeted to cLBP (T-APA, n = 92), points nontargeted to cLBP (NT-APA, n = 91), or waitlist education control (n = 89), and followed up to 6 months (6M). Participants in the APA groups received 4 weekly APA sessions; the education control group received 4 weekly educational sessions.</p><p><strong>Intervention: </strong>APA.</p><p><strong>Main outcomes and measures: </strong>Primary outcomes were pain (Numerical Rating Scale) and function (Roland-Morris Disability Questionnaire).</p><p><strong>Results: </strong>There were 272 participants (174 women [64%]; mean [SD] age 70.0 [6.95] years; 62% non-White). Compared to control, the T-APA group had significant improvement on pain from baseline to postintervention and 1-month (1M) follow-up by 1.73 and 1.26 points (P ≤ .001) respectively. The NT-APA group achieved similar improvements in pain. The improvement in function by T-APA and NT-APA was significant at postintervention by 1.89 and 2.68 points (P = .04 and .004) respectively, minimal at 1M follow-up, but significant at 6M in both APA groups. There were no statistically significant differences in treatment responses between the APA groups. Both APA groups had higher responder rates in pain and function at postintervention and 1M follow-up compared to the control group (odds ratio ranged from 2.11 to 6.32). The APA effects were sustained at 6M follow-up.</p><p><strong>Conclusions: </strong>APA treatments significantly improved pain and function compared to control; effects were sustained at 6M. APA should be recommended as a nonpharmacologic therapy for older adults with cLBP.</p><p><strong>Clinical trial registration number: </strong>Trial registry: Clinicaltrials.gov; Trial ID: NCT03589703; URL: https://clinicaltrials.gov/ct2/show/record/NCT03589703.</p>","PeriodicalId":19744,"journal":{"name":"Pain Medicine","volume":" ","pages":"515-526"},"PeriodicalIF":3.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12405757/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143730835","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}