发布求助
文献互助 智能选刊 最新文献

Pancreas最新文献

筛选
英文 中文
Screening of amino acids as a safe energy source for isolated rat pancreatic acini. 筛选氨基酸作为离体大鼠胰腺皮质的安全能量来源。
IF 2.9 4区 医学
Pancreas Pub Date : 2024-05-01 DOI: 10.1097/mpa.0000000000002350
Anastasiia M Zub, Bohdan O Manko, Volodymyr V Manko
{"title":"Screening of amino acids as a safe energy source for isolated rat pancreatic acini.","authors":"Anastasiia M Zub, Bohdan O Manko, Volodymyr V Manko","doi":"10.1097/mpa.0000000000002350","DOIUrl":"https://doi.org/10.1097/mpa.0000000000002350","url":null,"abstract":"Amino acids play an essential role in protein synthesis, metabolism and survival of pancreatic acini. Adequate nutritional support is important for acute pancreatitis treatment. However, high concentrations of arginine and lysine may induce acute pancreatitis. The study aimed to identify the most suitable L-amino acids as safe energy sources for pancreatic acinar cells.","PeriodicalId":19733,"journal":{"name":"Pancreas","volume":"8 1","pages":""},"PeriodicalIF":2.9,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140836396","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Early Hypophosphatemia as a Prognostic Marker in Acute Pancreatitis. 作为急性胰腺炎预后标志的早期低磷血症
IF 2.9 4区 医学
Pancreas Pub Date : 2024-05-01 DOI: 10.1097/mpa.0000000000002344
Connor F Stewart, Esther A Adeniran, Dhiraj Yadav, Fred S Gorelick, Rodger A Liddle, Bechien Wu, Stephen J Pandol, Christie Y Jeon
{"title":"Early Hypophosphatemia as a Prognostic Marker in Acute Pancreatitis.","authors":"Connor F Stewart, Esther A Adeniran, Dhiraj Yadav, Fred S Gorelick, Rodger A Liddle, Bechien Wu, Stephen J Pandol, Christie Y Jeon","doi":"10.1097/mpa.0000000000002344","DOIUrl":"https://doi.org/10.1097/mpa.0000000000002344","url":null,"abstract":"Acute pancreatitis (AP) is a complex disease representing a significant portion of gastrointestinal-related hospitalizations in the U.S. Understanding risk factors of AP might provide attractive therapeutic targets. We evaluated hypophosphatemia as a risk factor for worse outcomes in AP.","PeriodicalId":19733,"journal":{"name":"Pancreas","volume":"44 1","pages":""},"PeriodicalIF":2.9,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140836312","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Lipase-to-Amylase Ratio for the Prediction of Clinically Relevant Postoperative Pancreatic Fistula following Pancreaticoduodenectomy. 预测胰十二指肠切除术后临床相关胰瘘的脂肪酶与淀粉酶比率
IF 2.9 4区 医学
Pancreas Pub Date : 2024-05-01 DOI: 10.1097/mpa.0000000000002345
Juanita N Chui, William A Ziaziaris, Christopher B Nahm, Talia Fuchs, Sumit Sahni, Christopher S H Lim, Anthony J Gill, Jaswinder S Samra DPhil, Anubhav Mittal
{"title":"Lipase-to-Amylase Ratio for the Prediction of Clinically Relevant Postoperative Pancreatic Fistula following Pancreaticoduodenectomy.","authors":"Juanita N Chui, William A Ziaziaris, Christopher B Nahm, Talia Fuchs, Sumit Sahni, Christopher S H Lim, Anthony J Gill, Jaswinder S Samra DPhil, Anubhav Mittal","doi":"10.1097/mpa.0000000000002345","DOIUrl":"https://doi.org/10.1097/mpa.0000000000002345","url":null,"abstract":"Postoperative pancreatic fistula(POPF) represents a leading cause of morbidity and mortality following major pancreatic resections. This study aimed to evaluate the use of post-operative drain fluid lipase-to-amylase ratio(LAR) for the prediction of clinically relevant fistulae(CR-POPF).","PeriodicalId":19733,"journal":{"name":"Pancreas","volume":"1 1","pages":""},"PeriodicalIF":2.9,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140836169","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Syndecan-1 Levels and Early Positive Fluid Balance Are Associated with Disease Severity in Acute Pancreatitis. Syndecan-1水平和早期体液平衡阳性与急性胰腺炎的病情严重程度有关。
IF 2.9 4区 医学
Pancreas Pub Date : 2024-05-01 DOI: 10.1097/mpa.0000000000002366
Antti Turunen, Krista Kuuliala, Antti Kuuliala, Pauli Puolakkainen, Leena Kylänpää, Johanna Hästbacka, Outi Lindström
{"title":"Syndecan-1 Levels and Early Positive Fluid Balance Are Associated with Disease Severity in Acute Pancreatitis.","authors":"Antti Turunen, Krista Kuuliala, Antti Kuuliala, Pauli Puolakkainen, Leena Kylänpää, Johanna Hästbacka, Outi Lindström","doi":"10.1097/mpa.0000000000002366","DOIUrl":"https://doi.org/10.1097/mpa.0000000000002366","url":null,"abstract":"To study fluid balance and endothelial glycocalyx degradation, reflected by syndedan-1 and heparan sulfate (HS) levels, in early stages of acute pancreatitis (AP).","PeriodicalId":19733,"journal":{"name":"Pancreas","volume":"1 1","pages":""},"PeriodicalIF":2.9,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140842352","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Second Primary Neuroendocrine Tumors: A Case Series. 第二原发性神经内分泌肿瘤：病例系列。
IF 1.7 4区 医学
Pancreas Pub Date : 2024-05-01 DOI: 10.1097/MPA.0000000000002348
Pamela O Emengo, Michelle K Kim, Celia M Divino
{"title":"Second Primary Neuroendocrine Tumors: A Case Series.","authors":"Pamela O Emengo, Michelle K Kim, Celia M Divino","doi":"10.1097/MPA.0000000000002348","DOIUrl":"10.1097/MPA.0000000000002348","url":null,"abstract":"","PeriodicalId":19733,"journal":{"name":"Pancreas","volume":"53 5","pages":"e467-e469"},"PeriodicalIF":1.7,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140904856","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Molecular Demonstration of the Tumorigenic Role of APC in Pancreatic Solid Pseudopapillary Neoplasm Widens the Spectrum of FAP-Associated Neoplasms. 胰腺实体假乳头状瘤中 APC 致癌作用的分子证据拓宽了 FAP 相关肿瘤的范围
IF 2.9 4区 医学
Pancreas Pub Date : 2024-05-01 DOI: 10.1097/MPA.0000000000002347
Amedeo Sciarra, Alina Lungu, Charles Bénière, Sofia Facchi, Maria Grazia Tibiletti, Anna Maria Chiaravalli, Ian Fournier, Jean-Philippe Rey, Igor Letovanec, Stefano La Rosa
{"title":"Molecular Demonstration of the Tumorigenic Role of APC in Pancreatic Solid Pseudopapillary Neoplasm Widens the Spectrum of FAP-Associated Neoplasms.","authors":"Amedeo Sciarra, Alina Lungu, Charles Bénière, Sofia Facchi, Maria Grazia Tibiletti, Anna Maria Chiaravalli, Ian Fournier, Jean-Philippe Rey, Igor Letovanec, Stefano La Rosa","doi":"10.1097/MPA.0000000000002347","DOIUrl":"10.1097/MPA.0000000000002347","url":null,"abstract":"","PeriodicalId":19733,"journal":{"name":"Pancreas","volume":"53 5","pages":"e466-e467"},"PeriodicalIF":2.9,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140904890","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Epidemiology and Prognostic Nomogram for Predicting Long-Term Disease-Specific Survival in Patients With Pancreatic Carcinoid Tumor: A SEER-Based Study. 预测胰腺类癌患者长期疾病特异性生存的流行病学和预后提名图：基于 SEER 的研究。
IF 2.9 4区 医学
Pancreas Pub Date : 2024-05-01 Epub Date: 2024-03-13 DOI: 10.1097/MPA.0000000000002320
Hai Lin, Yufang Li, Yutong Chen, Linjuan Zeng, Bixiang Li, Shili Chen
{"title":"Epidemiology and Prognostic Nomogram for Predicting Long-Term Disease-Specific Survival in Patients With Pancreatic Carcinoid Tumor: A SEER-Based Study.","authors":"Hai Lin, Yufang Li, Yutong Chen, Linjuan Zeng, Bixiang Li, Shili Chen","doi":"10.1097/MPA.0000000000002320","DOIUrl":"10.1097/MPA.0000000000002320","url":null,"abstract":"<p><strong>Objectives: </strong>Pancreatic carcinoid tumor (PCT) is described as a malignant form of carcinoid tumors. However, the epidemiology and prognostic factors for PCT are poorly understood.</p><p><strong>Materials and methods: </strong>The data of 2447 PCT patients were included in this study from the Surveillance, Epidemiology, and End Results database and randomly divided into a training cohort (1959) and a validation cohort (488). The epidemiology of PCT was calculated, and independent prognostic factors were identified to construct a prognostic nomogram for predicting long-term disease-specific survival (DSS) among PCT patients.</p><p><strong>Results: </strong>The incidence of PCT increased remarkably from 2000 to 2018. The 1-, 5-, and 10-year DSS rates were 96.4%, 90.3%, and 86.5%, respectively. Age at diagnosis, stage, surgery, radiotherapy, and chemotherapy were identified as independent prognostic factors to construct a prognostic nomogram. The C -indices; area under the receiver operating characteristic curves for predicting 1-, 5-, and 10-year DSS, and calibration plots of the nomogram in both cohorts indicated a high discriminatory accuracy, preferable survival predictive ability, and optimal concordances, respectively.</p><p><strong>Conclusions: </strong>The incidence of PCT has increased rapidly since 2000. In addition, we established a practical, effective, and accurate prognostic nomogram for predicting the long-term DSS of PCT patients.</p>","PeriodicalId":19733,"journal":{"name":"Pancreas","volume":" ","pages":"e424-e433"},"PeriodicalIF":2.9,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140294220","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Clinical significance of MUC-4 and associated proteins in Pancreatic and Periampullary Cancers. 胰腺癌和髓周癌中 MUC-4 及其相关蛋白的临床意义。
IF 2.9 4区 医学
Pancreas Pub Date : 2024-05-01 DOI: 10.1097/mpa.0000000000002340
Sumaira Rashid, Nidhi Singh, Safoora Rashid, Prasenjit Das, Surabhi Gupta, Shyam S Chauhan, Hem Chandra Sati, Nihar Ranjan Dash, Atul Sharma, Sharmistha Dey, Anoop Saraya
{"title":"Clinical significance of MUC-4 and associated proteins in Pancreatic and Periampullary Cancers.","authors":"Sumaira Rashid, Nidhi Singh, Safoora Rashid, Prasenjit Das, Surabhi Gupta, Shyam S Chauhan, Hem Chandra Sati, Nihar Ranjan Dash, Atul Sharma, Sharmistha Dey, Anoop Saraya","doi":"10.1097/mpa.0000000000002340","DOIUrl":"https://doi.org/10.1097/mpa.0000000000002340","url":null,"abstract":"This study primarily aimed to assess the expression of MUC-4 in patients with Pancreatic Ductal Adenocarcinoma (PDAC) as compared with controls and assess its clinical relevance.","PeriodicalId":19733,"journal":{"name":"Pancreas","volume":"44 1","pages":""},"PeriodicalIF":2.9,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140836397","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Research progress on the mechanism of acute hypertriglyceridemic pancreatitis. 急性高甘油三酯性胰腺炎机制的研究进展。
IF 2.9 4区 医学
Pancreas Pub Date : 2024-05-01 DOI: 10.1097/mpa.0000000000002364
Yiteng Meng, Peiyu Han, Xiaoyu Ma, Yiting He, Hetian Chen, Hongbo Ren
{"title":"Research progress on the mechanism of acute hypertriglyceridemic pancreatitis.","authors":"Yiteng Meng, Peiyu Han, Xiaoyu Ma, Yiting He, Hetian Chen, Hongbo Ren","doi":"10.1097/mpa.0000000000002364","DOIUrl":"https://doi.org/10.1097/mpa.0000000000002364","url":null,"abstract":"The incidence rate of hypertriglyceridemia pancreatitis (HTGP) has experienced a notable increase in recent years, with eclipsing alcohol as the second leading cause of acute pancreatitis (AP). HTGP is often associated with more severe local and systemic complications. Recognized as a metabolic disorder hypertriglyceridemia (HTG), holds significant relevance in the pathogenesis of HTGP, yet its mechanisms are not fully understood. Both primary (genetic) and secondary (acquired) factors contribute to elevated triglyceride (TG) levels, which concurrently influence the progression of HTGP. This article presents a comprehensive review of the evolving research on HTGP pathogenesis, encompassing lipid synthesis and metabolism, calcium signal transduction, inflammatory mediators, endoplasmic reticulum stress, autophagy, mitochondrial injury by fatty acids, oxidative stress response, genetic factors, and gene mutations. By unraveling the intricate mechanisms underlying HTGP, this article aims to enhance physicians' understanding of the disease and facilitate the development of potential targeted pharmacological interventions for patients.","PeriodicalId":19733,"journal":{"name":"Pancreas","volume":"90 1","pages":""},"PeriodicalIF":2.9,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140828886","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Quality of Life Following TPIAT: A Patient Experience Survey. TPIAT 治疗后的生活质量：患者体验调查。
IF 2.9 4区 医学
Pancreas Pub Date : 2024-05-01 DOI: 10.1097/mpa.0000000000002353
Laura Barthold, Kerrington D Smith, Sushela S Chaidarun, Dawn A Fischer, Timothy B Gardner
{"title":"Quality of Life Following TPIAT: A Patient Experience Survey.","authors":"Laura Barthold, Kerrington D Smith, Sushela S Chaidarun, Dawn A Fischer, Timothy B Gardner","doi":"10.1097/mpa.0000000000002353","DOIUrl":"https://doi.org/10.1097/mpa.0000000000002353","url":null,"abstract":"Total pancreatectomy with islet autotransplantation (TPIAT) is performed to improve the quality of life (QOL) of patients with chronic pancreatitis. Few reports have documented QOL following TPIAT, with none using the pancreatitis-specific Pancreatitis Quality of Life Instrument (PANQOLI). We surveyed patients at our center who underwent TPIAT to document postoperative QOL.","PeriodicalId":19733,"journal":{"name":"Pancreas","volume":"59 1","pages":""},"PeriodicalIF":2.9,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140828954","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
首页 上一页
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整，为了账户安全，请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
请完成安全验证×
相关产品
×
本文献相关产品
联系我们：info@booksci.cn Book学术提供免费学术资源搜索服务，方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号：481959085
Book学术官方微信