NeuroRehabilitationPub Date : 2025-05-01Epub Date: 2025-02-26DOI: 10.1177/10538135251315378
Gang Liu, Chin-Hsuan Chia, Hai-Jun Jia, Jia-Xi Chen, Wei-Ning Wang, Shan Tian, Yue Cao, Jun-Fa Wu, Yi Wu, Cui-Wei Yang
{"title":"Taking Food to Mouth: Correlation Between Repetitive Movement and Upper Limb Flexion Synergy After Stroke.","authors":"Gang Liu, Chin-Hsuan Chia, Hai-Jun Jia, Jia-Xi Chen, Wei-Ning Wang, Shan Tian, Yue Cao, Jun-Fa Wu, Yi Wu, Cui-Wei Yang","doi":"10.1177/10538135251315378","DOIUrl":"https://doi.org/10.1177/10538135251315378","url":null,"abstract":"<p><p>BackgroundPathological upper-limb synergistic movement is a prevalent symptom of post-stroke motor dysfunction and pose a significant challenge in the rehabilitation of hemiplegia. However, the underlying mechanisms remain elusive, hindering the development of effective therapeutic strategies.ObjectiveThis study aims to explore the mechanisms underlying pathological synergic movements post-stroke by examining the interrelationship between motor modules associated with upper limb flexion synergy and the repetitive action of \"taking food to the mouth.\"MethodsSurface electromyography (sEMG) was employed to capture the EMG signals of normal elbow flexion, the act of \"taking food to the mouth,\" and post-stroke upper limb flexion synergy. Non-negative matrix factorization (NMF) was employed to compare and analyze the corresponding modular and coefficient matrices derived from these three motor tasks.ResultsThe modular matrix associated with flexion synergy exhibited the most significant correlation with the \"taking food to the mouth\" task, whereas the coefficient matrix shared the lowest correlation.ConclusionUpper limb flexion synergy after stroke may be related to the activation of the highly excitatory motor module formed by previously repeated movement of \"taking food to mouth\".</p>","PeriodicalId":19717,"journal":{"name":"NeuroRehabilitation","volume":"56 3","pages":"384-393"},"PeriodicalIF":1.7,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144004866","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
NeuroRehabilitationPub Date : 2025-05-01Epub Date: 2025-02-12DOI: 10.1177/10538135241308786
Charlotte Moeyersons, Evgenia Karagiannidou, Sarah Al Omari, Eva Swinnen, Mahyar Firouzi
{"title":"Impact of Transcranial Direct Current Stimulation on Dual-Task Gait Performance in Parkinson's Disease: A Systematic Review.","authors":"Charlotte Moeyersons, Evgenia Karagiannidou, Sarah Al Omari, Eva Swinnen, Mahyar Firouzi","doi":"10.1177/10538135241308786","DOIUrl":"10.1177/10538135241308786","url":null,"abstract":"<p><p>BackgroundParkinson's disease (PD) impairs motor and cognitive functions, increasing fall risk during dual-task activities. While transcranial direct current stimulation (tDCS), a non-invasive brain stimulation technique, has been studied for improving these functions in PD, its effect on dual-task gait remains unclear.ObjectiveThis review aims to evaluate the effects of tDCS on dual-task gait performance in PD.MethodsA systematic search was conducted in PubMed, Embase, and Web of Science for studies published before September 2024. Eligible studies included PD patients, used tDCS, and measured dual-task gait performance. Two researchers independently assessed methodological quality using the Cochrane Risk of Bias tool.ResultsFour randomized controlled trials and four crossover studies, involving 222 PD patients (mean age 64.17 years, range 50.9-72) at Hoehn & Yahr stages 1-3, met the inclusion criteria. Three of six studies targeting the dorsolateral prefrontal cortex showed significant improvements in dual-task gait performance, particularly in gait speed (<i>p</i> ≤ 0.046), compared to sham. No significant improvements were observed with primary motor cortex or cerebellar stimulation (all <i>p</i>'s ≥ 0.100).ConclusionstDCS targeting the dorsolateral prefrontal cortex may improve dual-task gait performance in PD, but further studies are needed to refine protocols and confirm its therapeutic potential.</p>","PeriodicalId":19717,"journal":{"name":"NeuroRehabilitation","volume":"56 3","pages":"289-301"},"PeriodicalIF":1.8,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143976485","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
NeuroRehabilitationPub Date : 2025-03-01Epub Date: 2024-12-19DOI: 10.1177/10538135241296733
Buhyeon Yoon, Seonmi Park, Seungjun Oh, Joshua Sung H You
{"title":"Augmented Effect of Combined Robotic Assisted Gait Training and Proprioceptive Neuromuscular Facilitation-irradiation Technique on Muscle Activation and Ankle Kinematics in Hemiparetic Gait: A Preliminary Study.","authors":"Buhyeon Yoon, Seonmi Park, Seungjun Oh, Joshua Sung H You","doi":"10.1177/10538135241296733","DOIUrl":"https://doi.org/10.1177/10538135241296733","url":null,"abstract":"<p><p>BackgroundProprioceptive neuromuscular facilitation (PNF) alone has limited effectiveness in restoring gait, while robotic-assisted gait training (RAGT) improves motor relearning through repetitive, task-specific movements. Combining PNF with robotic gait training (PRGT) may enhance locomotor recovery by promoting proprioceptive awareness and muscle activation alongside repetitive gait retraining in stroke patients.ObjectiveThis study compares the immediate effects of PRGT and RAGT on ankle dorsiflexion and muscle activity in chronic hemiparetic stroke patients and healthy controls.MethodsThirty participants, including 15 stroke patients and 15 healthy controls, were randomly assigned to PRGT or RAGT for a single 30-min session. Muscle activity (pectoralis major, external oblique, internal oblique/transverse abdominis, rectus femoris, tibialis anterior) was measured using electromyography, while ankle dorsiflexion angle was assessed using a dual-axis inclinometer.ResultsPRGT significantly increased muscle activations compared to RAGT in stroke patients (<i>p</i> < 0.05). Additionally, there was a significant difference in ankle dorsiflexion between RAGT and PRGT in both groups (<i>p </i>< 0.05).ConclusionPRGT demonstrated superior immediate effects on muscle activation and ankle movement, suggesting that combining PNF with robotic-assisted gait training is beneficial for chronic stroke rehabilitation.</p>","PeriodicalId":19717,"journal":{"name":"NeuroRehabilitation","volume":"56 2","pages":"196-206"},"PeriodicalIF":1.7,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144027798","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
NeuroRehabilitationPub Date : 2025-03-01Epub Date: 2025-01-12DOI: 10.1177/10538135241304334
Zeynep Şafak İbişoğlu, Serdar Kilinc
{"title":"Comparison of Functional Electrical Stimulation Cycle vs. Conservative Rehabilitation on Functional Status and Muscle Features in Stroke Patients.","authors":"Zeynep Şafak İbişoğlu, Serdar Kilinc","doi":"10.1177/10538135241304334","DOIUrl":"https://doi.org/10.1177/10538135241304334","url":null,"abstract":"<p><p>BackgroundFunctional Electrical Stimulation (FES) Cycle is used in the rehabilitation of stroke.ObjectiveThe aim of this study is to investigate the effects of CR and FES cycle therapy on the functional status and muscle features in stroke patientsMethodsThe 1st Group(n = 15) received only CR for 6 weeks, and the 2nd Group(n = 15) received FES cycle 3 days a week for 4 weeks in addition to the CR treatment. Brunnstrom recovery staging(BRS), Fugl-Meyer lower extremity evaluation(FME); Berg Balance Scale(BBS), Functional Ambulation Classification(FAC), Barthel Index(BI), Fatigue Severity Scale(FSS), 6 min walk test(6mWT), knee extensor and knee flexor muscle strengths(KEMS, KFMS) in both groups were assessed before and after treatment(6th week). Pennate angle(PA) and rectus femoris muscle thickness(RFT) were measured.ResultsSignificant improvement was detected in BBS, FAS, BI, FME, 6mWT, KEMS, RFT scores after intra-group treatment compared to before treatment in both groups. Only the 2nd Group showed a significant difference in KFMS, FSS, BRS lower extremity, PA values after treatment compared to before. No significant superiority of the groups over each other was detected.ConclusionsCR and FES Cycle contribute to the improvement of the functional status of the patients, but their superiority over each other was not observed.</p>","PeriodicalId":19717,"journal":{"name":"NeuroRehabilitation","volume":"56 2","pages":"207-218"},"PeriodicalIF":1.7,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144035096","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A Systematic Review and Meta-Analysis of the Effectiveness of Mulligan Mobilization with Movement on Pain, Range of Motion, Function, and Flexibility in Patients with Sciatica.","authors":"Hisham Hussein, Mohamed Atteya, Aisha Ansari, Ehab Kamel","doi":"10.1177/10538135241301693","DOIUrl":"10.1177/10538135241301693","url":null,"abstract":"<p><p>BackgroundThe Mulligan techniques address lumbar disc lesions and related dysfunctions. However, the current body of evidence of its effectiveness remains limited.AimsTo assess the effectiveness of the Mulligan concept on pain alleviation, range of motion, function, and flexibility in patients with sciatica.MethodsThis meta-analysis included randomized controlled trials that applied Mulligan techniques to patients with sciatica and assessed outcomes such as pain, range of motion, function, or flexibility. We searched six electronic databases to identify the relevant trials. The methodological quality of the studies was evaluated using the Cochrane risk of bias assessment.ResultsA total of 21 randomized controlled trials (RCTs) were included in this study. Three primary Mulligan techniques were performed: spinal mobilization with leg movement (SMWLM), bent leg raise (BLR), and traction straight leg raise (TSLR). In this review, seven trials exhibited a high to moderate risk of bias, while the remaining trials demonstrated a low risk of bias. The analysis revealed that SMWLG could be beneficial in improving pain (standardized mean difference [SMD] = -0.58, 95% confidence interval [CI] = -0.82 to -0.33, p < .001) and function (SMD = -1.02, 95% CI = -1.87 to -0.17, p = .02). Additionally, BLR showed potential benefits in improving flexibility, particularly when combined with standard treatment (SMD = 0.59, 95% CI = 0.30 to 0.88, p < .001).ConclusionsSMWLG demonstrates greater improvements in pain and function compared to other Mulligan techniques in patients with sciatica. However, the limited number of trials and the overall low quality of the existing literature highlight the need for future high-quality research that encompasses all related Mulligan techniques.</p>","PeriodicalId":19717,"journal":{"name":"NeuroRehabilitation","volume":"56 2","pages":"83-96"},"PeriodicalIF":1.7,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144010769","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
NeuroRehabilitationPub Date : 2025-03-01Epub Date: 2025-01-12DOI: 10.1177/10538135241296775
Minkwon Cho, Taewoong Jeong, Yijung Chung
{"title":"The Feasibility of non-motorized Treadmill Training on Lower Extremity Muscle Strength, Balance, and Gait in Patients with Stroke: A Pilot Study.","authors":"Minkwon Cho, Taewoong Jeong, Yijung Chung","doi":"10.1177/10538135241296775","DOIUrl":"https://doi.org/10.1177/10538135241296775","url":null,"abstract":"<p><p>BackgroundNon-motorized treadmills have been used for health improvement in healthy individuals and for enhancing physical fitness in athletes. However, there is a lack of research focusing on their use with patients with stroke.ObjectiveThis study aims to assess the impact of non-motorized treadmill training on lower limb strength, balance, and gait in patients with stroke, and compare it with flat ground walking training.MethodsThe participants included 22 patients with stroke, divided into two groups: non-motorized treadmill training group (<i>n </i>= 11) and flat ground walking training group (<i>n </i>= 11). All participants underwent 20 training sessions, 30 min each, five times a week for four weeks. Outcome measures included the digital dynamometer, Medical Research Council scale (MRC), Berg Balance Scale (BBS), Four Square Step Test (FSST), 6-Minute Walk Test (6MWT), and GAITRite.ResultsThe non-motorized treadmill training group showed significant improvements compared to the flat ground walking group in hip abductor and extensor muscle strength, knee flexor and extensor muscle strength, MRC, BBS, FSST, 6MW and gait parameters (<i>p </i>< 0.05).ConclusionsNon-motorized treadmill training may be considered an effective gait rehabilitation method in clinical settings for patients experiencing stroke with reduced lower limb strength, balance, and walking ability.</p>","PeriodicalId":19717,"journal":{"name":"NeuroRehabilitation","volume":"56 2","pages":"186-195"},"PeriodicalIF":1.7,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144019255","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
NeuroRehabilitationPub Date : 2025-03-01Epub Date: 2025-03-20DOI: 10.1177/10538135241301692
Tao Jiang, Jiamin Yan, Xiaohan Li, Minguang Yang, Yueyang Zhuang, Zhimin Ding, Mengquan Tan, Sijia Xia, Rui Li, Wenju Wang, Feng Chen, Xi Xie, Weilin Liu
{"title":"tDCS Combined with CIMT for Post-stroke Upper Extremity Rehabilitation: A Systematic Review and Meta-Analysis.","authors":"Tao Jiang, Jiamin Yan, Xiaohan Li, Minguang Yang, Yueyang Zhuang, Zhimin Ding, Mengquan Tan, Sijia Xia, Rui Li, Wenju Wang, Feng Chen, Xi Xie, Weilin Liu","doi":"10.1177/10538135241301692","DOIUrl":"10.1177/10538135241301692","url":null,"abstract":"<p><p>BackgroundTranscranial direct current stimulation (tDCS) has been widely used as an adjunctive treatment for motor function after stroke.ObjectiveTo quantify the effect of tDCS combined with constraint-induced movement therapy (CIMT) on the functional recovery of the upper limb after stroke.MethodsBy May 2024, two independent authors screened relevant randomized controlled trials (RCTs) published in English from PubMed, Embase, Web of Science and the Cochrane Library. Publication bias was assessed using the Egger's test.ResultsOf the 221 retrieved records, seven publications met the criteria for systematic review and quantitative analysis. According to estimates of Hedges'g, significant effects were revealed from Fugl-Meyer Assessment for Upper Limbs (UL-FMA) for upper limb impairment (<i>g</i> = 0.587, 95% CI = 0.256 to 0.919, <i>p</i> < 0.05<i>)</i> and Motor Activity Log-Amount of Movement (MAL-AoM) for perceived amount of motor (<i>g</i> = 0.386, 95% CI = 0.030 to 0.743, <i>p</i> < 0.05). Significant results favoring combined therapy were not found in Motor Activity Log-Quality of Movement (MAL-QoM) (<i>g</i> = 0.181, 95% CI = -0.169 to 0.531, <i>p</i> > 0.05), grip strength (<i>g</i> = 0.135, 95% CI = -0.214 to 0.485, <i>p</i> > 0.05) or Wolf Motor Function Test (WMFT) (<i>g</i> = 0.210, 95% CI = -0.117 to 0.537, <i>p</i> > 0.05).ConclusionsOur findings confirmed that tDCS enhanced the effect of CIMT in improving upper limb impairment and perceived amount of motor in daily life after stroke.</p>","PeriodicalId":19717,"journal":{"name":"NeuroRehabilitation","volume":"56 2","pages":"97-112"},"PeriodicalIF":1.8,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144018133","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
NeuroRehabilitationPub Date : 2025-03-01Epub Date: 2025-04-22DOI: 10.1177/10538135251327280
Francesca Cecchi
{"title":"Does Nutritional Therapy Reduce Disability and Improve Activities of Daily Living After a Stroke? - A Cochrane Review Summary with Commentary.","authors":"Francesca Cecchi","doi":"10.1177/10538135251327280","DOIUrl":"https://doi.org/10.1177/10538135251327280","url":null,"abstract":"<p><p>BackgroundMalnutrition can severely impact post-stroke functional recovery, but the effects of nutritional therapy (NT) on disability and activities of daily living (ADL) after stroke are not thoroughly investigated.Objectivesthe aim of the Cochrane Review by Sakai et al. (2023) was to evaluate the effectiveness of NT in reducing disability and improving ADL after stroke. The aim of this Corner is to provide a summary of Sakai et al. with comments from a rehabilitation perspective.Methodsrandomised controlled trials (RCTs) enrolling persons with stroke, investigating NT (defined as the administration of supplemental nutrients), compared with placebo, usual care (UC), or another type of NT were searched. Disability (modified Rankin score-mRS) and activities of daily living (ADL) were the primary outcomes.ResultsThe review included 52 trials (11,926 participants) with most studies conducted in the acute phase (36) and 25 types of supplements used. There was no difference in disability nor all-cause mortality, but oral energy and protein supplements may improve ADL. There was a higher risk of diarrohea, hyper- and hypoglycemia in participants receiving NT.ConclusionsThe effects of NT on disability and ADL after stroke is still uncertain, while NT may associate to increased adverse events. Future research should focus on targeted nutritional interventions to improve function after stroke, based on a theoretical rationale.</p>","PeriodicalId":19717,"journal":{"name":"NeuroRehabilitation","volume":"56 2","pages":"254-256"},"PeriodicalIF":1.7,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143993403","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
NeuroRehabilitationPub Date : 2025-03-01Epub Date: 2025-02-20DOI: 10.1177/10538135241306674
C Massot, M A Guyot, A Blanchard, L Norberciak, C Donze
{"title":"Effectiveness of Aerobic Treadmill Training on Walking Distance in Patients with Multiple Sclerosis with Moderate Disability: A Randomised Controlled Multicentre Trial.","authors":"C Massot, M A Guyot, A Blanchard, L Norberciak, C Donze","doi":"10.1177/10538135241306674","DOIUrl":"https://doi.org/10.1177/10538135241306674","url":null,"abstract":"<p><p>BackgroundPatients with Multiple Sclerosis (PwMS) have gait disorders. The efficiency of treadmill training on walking distance is debatable.ObjectiveThis study evaluated the efficacy of a 6-week treadmill training program at heart rate at the first ventilatory threshold (HR<sub>VT1</sub>) on walking distance compared with a control group in PwMS.MethodsThis prospective, multicenter study included 46 PwMS with moderate disability which randomized into training group (TG) and control group (CG). Patients performed cardiopulmonary exercise test to determine HR<sub>VT1</sub>. TG realized walking treadmill training program at HR<sub>VT1</sub>: 18 sessions (3 sessions/week) over 6 weeks. The distance on the six-minute walk test (6MWT), Timed 25 foot walk, patient-reported walking ability, berg balance scale, fatigue scale, the HR at the end of the 6MWT (HR<sub>6MWT</sub>) were collected at baseline, 6 weeks and 12 weeks.ResultsThe 6MWT distance showed a significant overall group effect (30.6 m; 95%CI = (6.6; 54.6); <i>p </i>= 0.017). The perceived impact of walking was significantly decreased in the TG (-6.1; 95% CI = (-9.2; -2.9); p = 0.0006). No correlation was found between HR<sub>VT1</sub> and HR<sub>6MWT</sub>.ConclusionAerobic treadmill training significantly enhanced walking distance and reduced perceived walking difficulties in PwMS.</p>","PeriodicalId":19717,"journal":{"name":"NeuroRehabilitation","volume":"56 2","pages":"243-253"},"PeriodicalIF":1.7,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144004802","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}