NeuroRehabilitation最新文献

{"title":"Predictors of Anxiety Symptoms Over the 10 Years After TBI in Asian Americans/Pacific Islanders: A Model System Study.","authors":"Bani Malhotra, Stephanie Agtarap, Bridget Xia, Olivia Chapman, Mia E Dini, Amy Starosta, Daniel W Klyce, Juan Carlos Arango-Lasprilla, Umesh M Venkatesan, Paul B Perrin","doi":"10.1177/10538135261439933","DOIUrl":"10.1177/10538135261439933","url":null,"abstract":"<p><p>BackgroundAnxiety symptoms are common after traumatic brain injury (TBI), and its impact over time may be influenced by demographic and injury-related factors. Specifically, there is a need to characterize post-injury anxiety symptom trajectories after TBI in understudied racial/ethnic groups.ObjectiveTo examine demographic and injury-related predictors of anxiety trajectories over the first 10 years following TBI in an Asian American and Pacific Islander (AAPI) sample.MethodsParticipants were 272 individuals enrolled in the U.S. TBI Model System study. Participants self-identified as AAPI and completed the Generalized Anxiety Disorder-7 scale (GAD-7) at 1, 2, 5, and/or 10-year post-injury follow ups. Over the 10-year period, unconditional growth models assessed curvature of GAD-7 score trajectories, and hierarchical linear modeling (HLM) identified baseline predictors of those trajectories. Secondary HLMs assessed changes in anxiety trajectory slopes over time as a function of significant baseline predictors.ResultsClinically significant anxiety symptoms affected 10.9-13.4% of the participants across the four time points. Over 10 years, anxiety was characterized by a linear, flat/stable, low-level trajectory. A higher overall anxiety trajectory was predicted by lower educational attainment and pre-injury history (vs. no such history) of mental health treatment, with no significant interactions between these predictors over time.ConclusionsEducational background and pre-injury mental health history are risk factors in the development and maintenance of anxiety symptoms in AAPIs with TBI and should be considered in culturally responsive screening and intervention. The disaggregation of AAPI subgroups may be help reframe and target treatment efforts in this heterogeneous population.</p>","PeriodicalId":19717,"journal":{"name":"NeuroRehabilitation","volume":" ","pages":"668-677"},"PeriodicalIF":2.0,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147639518","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Home-Based Telerehabilitation for Core Stability in Hereditary Ataxia: Feasibility and Preliminary Effects of a Pilot RCT.","authors":"Maria Masbernat-Almenara, Selma Peláez-Hervás, Helena Fernández-Lago, Laura Serra-Rusiñol, Francesc Rubí-Carnacea, Oriol Martínez-Navarro, Carlos Tersa-Miralles, Esteban Muñoz, Esther Rubinat-Arnaldo, Rosa Cabanas-Valdés","doi":"10.1177/10538135261431333","DOIUrl":"10.1177/10538135261431333","url":null,"abstract":"<p><p>BackgroundCore stability exercises (CSE) have shown efficacy in improving trunk function in individuals with hereditary ataxia (HA), but adherence to home programs is often low. Telerehabilitation (TR) could facilitate remote program delivery.ObjectivesTo assess the feasibility and preliminary effects of a 7-week home-based CSE-TR in individuals with HA.MethodsIn this single-blind, two-arm randomized controlled pilot study, participants performed a CSE-TR program 5 days per week, over 7 weeks. Two TR formats were compared: the Mixed Group (MG) combined asynchronous training with weekly synchronous sessions, while the Asynchronous Group (AG) received weekly follow-up calls. Feasibility outcomes included recruitment, adherence, compliance and retention. Preliminary effects-assessed at baseline, 7 weeks, and 12 weeks-included balance, gait performance, lower limb strength, fall risk, ataxia severity, and balance confidence.ResultsTwelve individuals with HA (mean age 49.5 ± 20.6 years) completed the study with 100% of retention. Statistically significant improvements over time were observed in gait performance (p < 0.0001), the MG showed significant gains at 7 weeks (p = 0.002) that were not maintained at follow-up. A significant time × group interaction was found for gait performance favoring the MG in the short term (p = 0.003). Balance confidence showed significant differences both over time (p = 0.046) and between groups (p = 0.014), with an unexpected decline in the MG. No other outcome measures reached statistical significance.ConclusionA home-based CSE-TR program is feasible and safe for individuals with HA and may provide functional benefits. Larger trials are needed to confirm effectiveness and optimize adherence.</p>","PeriodicalId":19717,"journal":{"name":"NeuroRehabilitation","volume":" ","pages":"440-452"},"PeriodicalIF":2.0,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147634145","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Understanding the Link Between Spirituality and Neurorehabilitation: A Narrative Review.","authors":"Paul Olowoyo, Adefolarin Malomo, Kehinde Adigun, Anna Ranta, Mayowa Owolabi","doi":"10.1177/10538135261423944","DOIUrl":"10.1177/10538135261423944","url":null,"abstract":"<p><p>BackgroundSpirituality is an essentially universal human experience and is incorporated into concepts of health and well-being in many cultures. The spiritual domain of quality of life, spared in the disability paradox, may be harnessed for recovery through internal adaptation and coping skills. This can help the individual attain his/her full potential while optimizing health-related quality of life. This narrative review explored the role of spirituality in neurorehabilitation.MethodsWe conducted a narrative review of relevant articles published between 2000 and 2024 using the following search terms: \"spirituality\", \"spiritual care\", \"neurorehabilitation\", \"stroke rehabilitation\", \"brain injury rehabilitation\", \"spinal cord injury\", \"Parkinson's disease\", \"recovery\", \"neuroplasticity\", \"music therapy\". Similar articles were harmonized to avoid redundancy.ResultsWe retrieved 9,200 articles. After the removal of non-relevant duplicates, 50 articles were reviewed. We observed that many cultures have recognized the experience of spirituality and its impact on health for centuries. Recent advances in neuroradiology have enabled us to map such experiences to specific brain pathways. Their activation is associated with increased neuronal activities that potentially lead to the strengthening of existing synapses, the formation of new synapses, and spatial re-orientation of neuronal networks, suggesting that spiritual activation may favorably contribute to neuroplasticity. There is emerging evidence that supports the benefits of spiritually-based interventions such as meditation, prayer, singing, dancing, yoga, and others for improvement in patients.ConclusionWhile observational data are strong, more randomized controlled trials (RCTs) are needed to establish the role of spiritual interventions and inclusion in neurorehabilitation guidelines towards achieving holistic restoration.</p>","PeriodicalId":19717,"journal":{"name":"NeuroRehabilitation","volume":" ","pages":"406-412"},"PeriodicalIF":2.0,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147390628","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Modified Constraint-Induced Movement Therapy with Trunk Restraint for Upper Extremity Functional Motor Recovery, Balance and Health-Related Quality of Life in Chronic Stroke: A Single-Blinded Randomized Controlled Clinical Trial.","authors":"Abdulrhman M Shahhar, Abdul Rahim Shaik, Vandana Esht, Mohammed Mansour Alshehri, Karthick Balasubramanian, Ramya Ramasamy Sanjeevi, Khadijah Abdulrahman Alfaleh, Weam Okab Alsalem, Wajd A Fathi, Shaima A Alothman","doi":"10.1177/10538135261417372","DOIUrl":"10.1177/10538135261417372","url":null,"abstract":"<p><p>BackgroundThe upper extremity functional recovery remains a major challenge for specialists during post stroke rehabilitation, pertaining to adoption of various compensatory strategies by patients leading to motor redundancy and persistent functional limitations.ObjectivesThe study aimed to evaluate the effectiveness of Patient Tailored-Modified Constraint Induced Movement Therapy (mCIMT) combined with Trunk Restraint (TR) on Upper Extremity motor ability, balance, and health-related quality of life (HR-QOL) in chronic stroke survivors.MethodsIn this patient-blinded trial, 34 voluntary patients with chronic hemiplegia (>6 months post-stroke), aged 45-65 years, with Mini-Mental State Examination (MMSE) scores > 24 having and spasticity graded 1 or 1 + on Modified Ashworth Scale (MAS), were recruited and randomly allocated (1:1) to experimental or control groups. The experimental group received 60 min of Conventional Physical Therapy (CPT) plus 120 min of mCIMT with TR, while the control group received CPT treatment alone, three sessions per week for six consecutive weeks. Outcomes were assessed pre- and post-intervention using the Wolf Motor Function Test (WMFT), Berg Balance Scale (BBS), and Stroke Specific Quality of Life Scale (SS-QOL).ResultsBoth groups demonstrated significant improvements from baseline to post-intervention (<i>p</i> < 0.01) across all outcome measures. However, the experimental group exhibited significantly greater gains in functional ability, as reflected by SS-QOL scores (<i>p</i> < 0.005), compared to the control group.ConclusionEighteen sessions of mCIMT along with TR, delivered over six weeks in combination with CPT, demonstrated significant improvements in all outcomes (WMFT, BBS, and SS-QOL) among chronic stroke patients and is as beneficial to individual rehabilitation as conventional therapy alone.<b>Trial registry name and URL:</b> ClinicalTrails.gov (Registration ID: NCT06692569).</p>","PeriodicalId":19717,"journal":{"name":"NeuroRehabilitation","volume":" ","pages":"413-428"},"PeriodicalIF":2.0,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146106621","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Physiotherapy Interventions for Chronic Stroke: A Systematic Review of Functionality and Quality of Life Outcomes.","authors":"Andrea Razón Karake, Ximena Arantza Valencia Silva, Ángela Hernández Suárez, Teresa Ponce-Lopez, Antonio Ibarra, Yolanda Cruz-Martínez","doi":"10.1177/10538135261420356","DOIUrl":"10.1177/10538135261420356","url":null,"abstract":"<p><p>IntroductionStroke is a neurological alteration which significantly impacts patient's functional abilities and quality of life. Physiotherapy interventions, including therapeutic exercise, robotic therapy, electrotherapy and hydrotherapy, have demonstrated positive effects in addressing the sequelae that persist in the chronic phase.MethodsThis systematic review was registered in PROSPERO (CRD420251102428). Searches were conducted in Cochrane, PubMed, PEDro, Scopus, and Google Scholar. Randomized controlled trials of physiotherapy interventions in chronic stroke were included if they reported outcomes for functionality and quality of life. Methodological quality was assessed using the PEDro scale. 35 articles met the inclusion criteria, of which 18 focused on therapeutic exercise, 8 on robotic therapy, 8 on electrotherapy, and 1 on hydrotherapy, comprising a total of 2,412 patients.ResultsTherapeutic exercise is the most extensively studied intervention in chronic stroke, consistently demonstrating the most favorable outcomes in functionality. Robotic therapy was the second modality showing improvements in functionality, particularly in gait, balance and hand function. Electrotherapy, along with robotic therapy showed the greatest impact on quality of life outcomes. Evidence for hydrotherapy remains limited, with a single trial reporting improvements in balance. Overall, these results suggest that no single physiotherapy modality is superior across all domains, emphasizing the need for a multimodal and individualized approach in chronic stroke rehabilitation.ConclusionPhysiotherapy interventions in chronic stroke show clear benefits, with therapeutic exercise showing the greatest impact on functional recovery and electrotherapy and robotic therapy on quality of life.</p>","PeriodicalId":19717,"journal":{"name":"NeuroRehabilitation","volume":" ","pages":"346-370"},"PeriodicalIF":2.0,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147390608","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Characteristics and Trends of Randomized Controlled Trials on Post-Stroke Unilateral Spatial Neglect Rehabilitation: A Systematic Review.","authors":"Sarvenaz Mehrabi, Mohammad R Safaei-Qomi, Cecilia Flores-Sandoval, Jamie L Fleet, Ricardo Viana, Sean Dukelow, Robert Teasell","doi":"10.1177/10538135261420360","DOIUrl":"10.1177/10538135261420360","url":null,"abstract":"<p><p>BackgroundUnilateral spatial neglect (USN) is a common post-stroke deficit that adversely affects activities of daily living and functional independence. Despite advancements in stroke rehabilitation research, USN-specific rehabilitation studies remain relatively limited, contributing to a gap in evidence-based clinical practice.ObjectiveTo characterize randomized controlled trials (RCTs) evaluating post-stroke USN rehabilitation interventions and to provide an overview of the intervention types studied and gaps in the current literature.MethodsSystematic searches of MEDLINE, Embase, Scopus, CINAHL, and PsycINFO were conducted from inception to December 31, 2024. The methodological quality of included RCTs was assessed using the PEDro scale.ResultsA total of 123 RCTs were included, collectively enrolling 3,419 participants. The annual number of trials has remained stable in recent years. The mean sample size was 27.8, and the majority of RCTs (60.2%) were conducted in the subacute phase post-stroke. A total of 44 unique types of intervention were examined across the 123 RCTs. Top-down interventions were evaluated in 49 RCTs (39.8%), while bottom-up therapies were examined in 82 RCTs (66.6%), and pharmacological interventions were used in only 6 studies (4.9%).ConclusionsFuture RCTs on neglect should recruit larger sample sizes, evaluate the efficacy of combined interventions, and implement time-sensitive treatment strategies to maximize gains in the earlier post stroke phase. Additionally, RCTs are needed to specifically address the impact of treatment timing on outcomes, and the long-term effects.</p>","PeriodicalId":19717,"journal":{"name":"NeuroRehabilitation","volume":" ","pages":"371-380"},"PeriodicalIF":2.0,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146227972","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Safety, Feasibility, and Efficacy of the Lumbar Type Hybrid Assistive Limb with Brain Injury-Related Lower Limb Hemiparesis in the Acute Phase: A Pilot Randomized Crossover Trial.","authors":"Gakuto Kitamura, Hiroki Tanaka, Manabu Nankaku, Takayuki Kikuchi, Takumi Kawano, Tomoyo Komatsu, Susumu Miyamoto, Ryosuke Ikeguchi","doi":"10.1177/10538135261423946","DOIUrl":"10.1177/10538135261423946","url":null,"abstract":"<p><p>PurposeThis study aimed to investigate the safety, feasibility, and effect on hemiparetic muscle activity during sit-to-stand exercises using the lumbar type HAL in patients with acute-phase lower limb hemiparesis caused by ischemic stroke, cerebral hemorrhage, or postoperative brain tumor.MethodsThis randomized crossover study included twelve participants (ischemic stroke: 6, cerebral hemorrhage: 2, brain tumor: 4) for part 1, which assessed safety and comfort of sit-to-stand exercise using HAL, and ten participants (ischemic stroke: 4, cerebral hemorrhage: 3, brain tumor: 3) for part 2, which investigated the effect of HAL on muscle activities during sit-to-stand exercises. Participants performed either five sets (part 1) or a single set (part 2) of ten repetitions of sit-to-stand exercises under two conditions: with and without HAL assistance. Outcome included vital signs (blood pressure, heart rate, and percutaneous oxygen saturation), fatigue level in part 1. Muscle activity of bilateral gluteus maximus, biceps femoris, and vastus lateralis during the exercises were assessed in part 2. Outcomes were compared between the two conditions.ResultsThe results demonstrated that there were no significant changes in vital signs and fatigue between two conditions. Furthermore, HAL effectively increased muscle activity (μV) in the hemiparetic side vastus lateralis during the exercises (median, quartile range: 101.1, 55.8-125.9 vs. 79.9, 52.0-103.3, p = 0.03).ConclusionsThese findings suggest that the lumbar type HAL can be safely and feasibly used in patients with acute brain injury-related lower limb paresis, with potential effects on hemiparetic muscle activation. However, these results should be interpreted cautiously as exploratory observations.Registry informationClinical utility of cybernic system for patients with neurological diseases causing who need comprehensive nursing care (Clinical utility of cybernic system for patients with neurological diseases causing who need comprehensive nursing care (CUCSPND)), https://jrct.niph.go.jp/en-latest-detail/jRCTs052180074, jRCTs052180074.The effect of motor therapy using robot suit HAL for the patients with damaged brain (motor therapy using robot suit HAL), https://jrct.niph.go.jp/en-latestdetail/jRCTs052180223, jRCTs052180223.</p>","PeriodicalId":19717,"journal":{"name":"NeuroRehabilitation","volume":" ","pages":"429-439"},"PeriodicalIF":2.0,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147317712","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Multidisciplinary Management of Post-Stroke Depression: A Survey of Therapists' Observations.","authors":"Diletta Maria Pisaniello, Ingela Kerstin Johnson, Sara Anello, Pier Carlo Battain","doi":"10.1177/10538135261420363","DOIUrl":"10.1177/10538135261420363","url":null,"abstract":"<p><p>BackgroundPost-stroke depression is common yet frequently underdiagnosed, substantially hindering rehabilitation engagement and functional recovery. Understanding its impact from the clinician's perspective is critical to optimizing care.ObjectiveThis study aimed to explore how post-stroke depression affects patient autonomy and rehabilitation processes from the viewpoint of occupational, physical, and speech therapists.MethodsAn observational mixed-methods study was conducted via an online survey of 111 neurorehabilitation therapists. Quantitative data were analyzed descriptively; qualitative responses from open-ended questions underwent thematic analysis.ResultsTherapists reported that post-stroke depression profoundly influences rehabilitation through: (1) reduced patient motivation and collaboration; (2) the consequent need for adapted therapeutic strategies (e.g., modified goal-setting and relational approaches); (3) significant professional challenges in patient engagement; and (4) an increased emotional burden on therapists. Consequently, interventions are routinely modified, requiring more time, interdisciplinary coordination, and psychological support.ConclusionsThis study underscores that post-stroke depression necessitates a fundamentally adapted, team-based rehabilitation approach tailored to motivational deficits. The findings highlight the importance of early screening, therapist training in motivational and relational skills, and structured support for clinicians to improve both patient outcomes and therapist well-being.</p>","PeriodicalId":19717,"journal":{"name":"NeuroRehabilitation","volume":" ","pages":"463-473"},"PeriodicalIF":2.0,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146227932","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Modeling Long-Term Depression Trajectories After Spinal Cord Injury Using Irregularly Sampled Assessments and Rehabilitation Baseline Predictors.","authors":"Alejandro García-Rudolph, Maria Dolors Soler, Anna Gilabert, Eloy Opisso, Joan Saurí","doi":"10.1177/10538135261433166","DOIUrl":"10.1177/10538135261433166","url":null,"abstract":"<p><p>PurposeTo identify and characterize latent trajectories of depression using growth mixture modeling (GMM) applied to irregularly timed assessments spanning up to 20 years post-injury, examine baseline rehabilitation variables significantly associated with trajectory membership, and determine predictors of sustained depressive burden.MethodsThis retrospective observational cohort study included adults with traumatic or non-traumatic spinal cord injury admitted for inpatient rehabilitation within 3 months post-injury (2005-2023), with follow-up extending until May 2025. Depressive symptoms were assessed using the Hospital Anxiety and Depression Scale (HADS-D) at admission, discharge, and follow-up, totaling 3,258 assessments (n = 679 patients). GMM identified latent trajectories while accommodating irregularly spaced assessments. Predictors of trajectory membership were analyzed through multivariable regression with quantified model discrimination.ResultsA 3-class GMM solution provided optimal fit (entropy=0.75). Most participants (81.6%) followed a stable low-depression trajectory (Class 1). A borderline depression trajectory (Class 2; 8.4%) remained persistently elevated, while a probable depression trajectory (Class 3; 10.0%) displayed delayed worsening peaking at 5-7 years post-injury. Class 3 included a significantly higher proportion of non-traumatic injuries (63%) and females (44.1%), with most patients (85.3%) showing no depressive symptoms during rehabilitation, but later exhibiting a marked increase in depressive burden. Logistic regression predicting Class 2 achieved good discrimination (AUC=0.81; 95% CI, 0.65-0.97), identifying baseline depressive symptoms, tetraplegia, female sex, and primary level of education as significant predictors.ConclusionsIrregularly sampled follow-ups revealed distinct depression trajectories, including delayed-onset risk. Findings emphasize early rehabilitation-based screening and long-term monitoring to target follow-up and psychological support.</p>","PeriodicalId":19717,"journal":{"name":"NeuroRehabilitation","volume":" ","pages":"486-499"},"PeriodicalIF":2.0,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147513836","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficacy of Robot-Assisted Training Plus Acupuncture Therapy on Lower Limb Functional Recovery in Stroke Patients: A Systematic Review and Meta-Analysis.","authors":"Weihao Ke, Xiaoxuan Ren, Hongxin Cheng, Liang Yang, Xiaomin Lai, Zhenyu Wang","doi":"10.1177/10538135261420364","DOIUrl":"10.1177/10538135261420364","url":null,"abstract":"<p><p>PurposeTo assess the effectiveness of robot-assisted training (RAT) plus acupuncture therapy (AT) on lower limb functional recovery in stroke patients.MethodsThe study protocol was registered with INPLASY (INPLASY2024120107). We searched CNKI, Wanfang, VIP, CBM, PubMed, Embase, Web of Science, and Cochrane Library for RCTs comparing RAT plus AT versus conventional rehabilitation, RAT alone, or AT alone. The risk of bias was assessed using the Cochrane risk-of-bias tool 2.0.ResultsTwenty-one studies (n = 1821) were included. Meta-analyses showed RAT plus AT yielded superior improvements in FMA-LE (MD = 4.02, 95% CI [3.12, 4.93], I² = 89%), FAC (MD = 0.66, 95% CI [0.43, 0.89], I² = 86%), MBI (MD = 9.88, 95% CI [6.43, 13.33], I² = 83%), and BBS (MD = 6.79, 95% CI [5.43, 8.16], I² = 90%). Significant improvements were also observed in gait parameters: step length (MD = 7.42, 95% CI [6.48, 8.36], I² = 12%), step speed (MD = 0.16, 95% CI [0.12, 0.21], I² = 90%), and step width (MD = -2.22, 95% CI [3.96, -0.48], I² = 90%). Sensitivity analyses verified the robustness of these findings.ConclusionRAT plus AT effectively ameliorates post-stroke lower limb dysfunction, demonstrating superior improvements in motor function, gait parameters, and daily living activities compared to monotherapies.</p>","PeriodicalId":19717,"journal":{"name":"NeuroRehabilitation","volume":" ","pages":"381-395"},"PeriodicalIF":2.0,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147317719","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}