NeuroRehabilitation最新文献

{"title":"Uncertainty in Illness and Posttraumatic Growth among Young and Middle-Aged Stroke Patients: A Mediation Model of Coping Styles and Rumination.","authors":"Xinyi Chen, Jiao Yang, Xin Zhou, Xi Cao","doi":"10.1177/10538135261445651","DOIUrl":"https://doi.org/10.1177/10538135261445651","url":null,"abstract":"<p><p>BackgroundStroke keeps on the rise in young and middle-aged individuals. This group may experience positive psychological changes, such as posttraumatic growth (PTG), which facilitates recovery. However, PTG in young and middle-aged stroke patients is not yet fully understood in China. This study aims to examine the associations between uncertainty in illness and PTG among young and middle-aged patients with stroke, and to explore whether coping styles and rumination are associated with this relationship.MethodsA cross-sectional study was conducted from September 2022 to February 2023 in a tertiary hospital in Guangzhou, China, enrolling 204 stroke patients aged 18 to 59 years. Sociodemographic and clinical data were obtained via interviews and medical records. Data on PTG, uncertainty in illness, coping styles, and rumination were collected via the Posttraumatic Growth Inventory (PTGI), Mishel Uncertainty in Illness Scale for Adults (MUIS-A), Simplified Coping Style Questionnaire (SCSQ), and Event-Related Rumination Inventory (ERRI). Data were analyzed using Pearson correlation and path analysis in SPSS 26.0 and Mplus 8.3.ResultsTotally 204 participants were included. The mean score for PTG was $52.27 ± 12.06. Uncertainty in illness was negatively correlated with PTG (<i>β</i>= -0.61, <i>p</i> < 0.01). Path analysis revealed that positive coping styles (<i>β</i>= -0.21, <i>p</i> < 0.001) and deliberate rumination (<i>p</i> = -0.12, <i>p</i> = 0.002) were significantly associated with the relationship between uncertainty in illness and PTG. These variables accounted for 44.7% and 25.9% of the total effect, respectively.ConclusionUncertainty in illness is significantly associated with PTG among young and middle-aged stroke patients, such association was mediated by positive coping styles and deliberate rumination.</p>","PeriodicalId":19717,"journal":{"name":"NeuroRehabilitation","volume":" ","pages":"10538135261445651"},"PeriodicalIF":1.8,"publicationDate":"2026-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147841251","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Outpatient Occupational Therapy, Physiotherapy, and Speech Language Pathology Interventions for People with Functional Neurologic Disorder: A Scoping Review.","authors":"Elliot J Gann, Alec M Grove, Elizabeth Erb-Trefilek, Julianne Pearson, Meagan Watson, Mark M Mañago","doi":"10.1177/10538135261440539","DOIUrl":"https://doi.org/10.1177/10538135261440539","url":null,"abstract":"<p><p>BackgroundFunctional neurologic disorder (FND) is a disabling condition commonly managed by occupational therapists (OT), physiotherapists (PT), and speech-language pathologists (SLP). While consensus recommendations for OT, PT, and SLP provide general principles for assessment and treatment, there is limited understanding of how interventions are delivered or how outcomes are measured, particularly in the outpatient setting.PurposeThis scoping review describes the characteristics (mode, frequency, duration) of outpatient OT, PT, and SLP interventions for individuals with FND, assesses their alignment with consensus FND recommendations, and maps outcome measures to the International Classification of Functioning (ICF) model.MethodsThree electronic databases (Medline, Embase, and CINAHL) were searched for articles that included individuals diagnosed with FND, reported characteristics of outpatient OT, PT, or SLP interventions, and were published in English.ResultsThirty-one studies were included (PT, n = 14, SLP, n = 8, multidisciplinary n = 6, and OT, n = 3). Most studies (n = 22, 71%) included interventions that aligned with FND recommendations and commonly consisted of education, movement retraining with diverted attention, and symptom management plans. Intervention frequency ranged from daily sessions over one week to twice-monthly sessions across three months. The outcome measures were primarily patient-rated, and most frequently mapped to the body structure and function domain of the ICF.ConclusionsOutpatient OT, PT, and SLP interventions predominantly included components of FND recommendations yet varied in mode, frequency, and outcome measure selection. Future research is needed to examine the optimal parameters and modes, compare specific interventions, and identify outcomes that encompass all ICF domains.</p>","PeriodicalId":19717,"journal":{"name":"NeuroRehabilitation","volume":" ","pages":"10538135261440539"},"PeriodicalIF":1.8,"publicationDate":"2026-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147841331","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficacy of Manual Massage Therapy on Spasticity in Patients with Stroke and Cerebral Palsy: A Systematic Review and Meta-Analysis.","authors":"Hankyu Park, Byoungha Hwang, Minbong Kang","doi":"10.1177/10538135261447895","DOIUrl":"https://doi.org/10.1177/10538135261447895","url":null,"abstract":"<p><p>BackgroundSpasticity commonly complicates upper motor neuron syndromes, reducing quality of life. While manual massage is widely used to manage muscle tone, its overall efficacy remains unquantified.ObjectiveTo evaluate the effectiveness of pure manual massage interventions (without instruments) for reducing spasticity in patients with stroke and cerebral palsy and clarify its clinical neurorehabilitation role.MethodsA systematic search of multiple databases identified randomized controlled trials (RCTs) investigating manual massage for spasticity in patients with stroke or cerebral palsy. The primary outcome was spasticity measured by the Modified Ashworth Scale. Bias was assessed using RoB 2.0. We conducted a random-effects meta-analysis calculating pooled standardized mean differences (SMDs).ResultsFour RCTs (n = 253) were included. Manual massage was associated with reduced spasticity compared with controls (SMD=0.59, 95% CI 0.31-0.87), with low-to-moderate heterogeneity (I²=35.7%). Subgroup analysis demonstrated consistent, significant improvements in children with cerebral palsy (SMD=0.56, I²=0%). Conversely, results in adult stroke populations were non-significant with substantial heterogeneity (SMD=0.78, I²=73%). Despite spasticity reductions, downstream functional outcomes were not consistently improved.ConclusionsManual massage may be considered as a preparatory adjunct for reducing spasticity, particularly in children with cerebral palsy. However, the evidence base remains limited, most included interventions were delivered alongside conventional rehabilitation, and functional benefits were not consistently demonstrated.</p>","PeriodicalId":19717,"journal":{"name":"NeuroRehabilitation","volume":" ","pages":"10538135261447895"},"PeriodicalIF":1.8,"publicationDate":"2026-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147841290","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficacy of Multi-Domain Telerehabilitation in Patients with Stroke: A Non-Inferiority, Single-Blind, Randomized Controlled Trial.","authors":"Alessandro Picelli, Pawel Kiper, Valentina Varalta, Mirko Filippetti, Anna Righetti, Elisa Evangelista, Rita Di Censo, Cristina Fonte, Sara Federico, Luisa Cacciante, Alessia Carletto, Andrea Turolla, Michela Agostini, Paolo Tonin, Claudia Giacomozzi, Nicola Smania","doi":"10.1177/10538135261445401","DOIUrl":"https://doi.org/10.1177/10538135261445401","url":null,"abstract":"<p><p>ObjectiveAlthough telerehabilitation has emerged as a promising and accessible alternative to traditional in-person therapy, robust evidence supporting its clinical effectiveness across multiple functional domains remains limited. We tested the non-inferiority of synchronous multi-domain telerehabilitation for motor, cognitive, language, and disability outcomes in stroke survivors.DesignBicentric, single-blind (assessor-blinded), randomized controlled non-inferiority trial.MethodsFifty-six participants were randomized to home-based telerehabilitation or conventional outpatient therapy. Both groups completed twenty real-time supervised sessions over four weeks. The primary outcome was change in Fugl-Meyer Assessment upper-extremity motor score (0-66); secondary outcomes included Fugl-Meyer Assessment lower-extremity motor (0-34), Aachen Aphasia Test (Italian version) naming/written language/comprehension, Oxford Cognitive Screen orientation and memory subtests, and Barthel Index. Non-inferiority was evaluated using a prespecified margin (Δ=-5.2) and confidence-interval-based linear mixed-effects models (per-protocol primary, intention-to-treat sensitivity); non-inferiority was concluded if the lower bound of the 95% CI for the adjusted between-group contrast at T1 (telerehabilitation minus conventional) was > -Δ.ResultsThe adjusted between-group difference in change for the primary outcome was compatible with non-inferiority at post-treatment, with consistent results in sensitivity analyses. No significant between-group differences were observed in language, cognitive, or functional independence outcomes, and findings were similar at one-month follow-up.ConclusionsSynchronous multi-domain telerehabilitation appears feasible and yields short-term motor recovery comparable to standard outpatient rehabilitation within a prespecified non-inferiority framework. Interpretation is limited by the short follow-up and restricted cognitive outcome coverage.</p>","PeriodicalId":19717,"journal":{"name":"NeuroRehabilitation","volume":" ","pages":"10538135261445401"},"PeriodicalIF":1.8,"publicationDate":"2026-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147819091","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Home-Based Telerehabilitation for Core Stability in Hereditary Ataxia: Feasibility and Preliminary Effects of a Pilot RCT.","authors":"Maria Masbernat-Almenara, Selma Peláez-Hervás, Helena Fernández-Lago, Laura Serra-Rusiñol, Francesc Rubí-Carnacea, Oriol Martínez-Navarro, Carlos Tersa-Miralles, Esteban Muñoz, Esther Rubinat-Arnaldo, Rosa Cabanas-Valdés","doi":"10.1177/10538135261431333","DOIUrl":"10.1177/10538135261431333","url":null,"abstract":"<p><p>BackgroundCore stability exercises (CSE) have shown efficacy in improving trunk function in individuals with hereditary ataxia (HA), but adherence to home programs is often low. Telerehabilitation (TR) could facilitate remote program delivery.ObjectivesTo assess the feasibility and preliminary effects of a 7-week home-based CSE-TR in individuals with HA.MethodsIn this single-blind, two-arm randomized controlled pilot study, participants performed a CSE-TR program 5 days per week, over 7 weeks. Two TR formats were compared: the Mixed Group (MG) combined asynchronous training with weekly synchronous sessions, while the Asynchronous Group (AG) received weekly follow-up calls. Feasibility outcomes included recruitment, adherence, compliance and retention. Preliminary effects-assessed at baseline, 7 weeks, and 12 weeks-included balance, gait performance, lower limb strength, fall risk, ataxia severity, and balance confidence.ResultsTwelve individuals with HA (mean age 49.5 ± 20.6 years) completed the study with 100% of retention. Statistically significant improvements over time were observed in gait performance (p < 0.0001), the MG showed significant gains at 7 weeks (p = 0.002) that were not maintained at follow-up. A significant time × group interaction was found for gait performance favoring the MG in the short term (p = 0.003). Balance confidence showed significant differences both over time (p = 0.046) and between groups (p = 0.014), with an unexpected decline in the MG. No other outcome measures reached statistical significance.ConclusionA home-based CSE-TR program is feasible and safe for individuals with HA and may provide functional benefits. Larger trials are needed to confirm effectiveness and optimize adherence.</p>","PeriodicalId":19717,"journal":{"name":"NeuroRehabilitation","volume":" ","pages":"440-452"},"PeriodicalIF":1.8,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147634145","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Understanding the Link Between Spirituality and Neurorehabilitation: A Narrative Review.","authors":"Paul Olowoyo, Adefolarin Malomo, Kehinde Adigun, Anna Ranta, Mayowa Owolabi","doi":"10.1177/10538135261423944","DOIUrl":"10.1177/10538135261423944","url":null,"abstract":"<p><p>BackgroundSpirituality is an essentially universal human experience and is incorporated into concepts of health and well-being in many cultures. The spiritual domain of quality of life, spared in the disability paradox, may be harnessed for recovery through internal adaptation and coping skills. This can help the individual attain his/her full potential while optimizing health-related quality of life. This narrative review explored the role of spirituality in neurorehabilitation.MethodsWe conducted a narrative review of relevant articles published between 2000 and 2024 using the following search terms: \"spirituality\", \"spiritual care\", \"neurorehabilitation\", \"stroke rehabilitation\", \"brain injury rehabilitation\", \"spinal cord injury\", \"Parkinson's disease\", \"recovery\", \"neuroplasticity\", \"music therapy\". Similar articles were harmonized to avoid redundancy.ResultsWe retrieved 9,200 articles. After the removal of non-relevant duplicates, 50 articles were reviewed. We observed that many cultures have recognized the experience of spirituality and its impact on health for centuries. Recent advances in neuroradiology have enabled us to map such experiences to specific brain pathways. Their activation is associated with increased neuronal activities that potentially lead to the strengthening of existing synapses, the formation of new synapses, and spatial re-orientation of neuronal networks, suggesting that spiritual activation may favorably contribute to neuroplasticity. There is emerging evidence that supports the benefits of spiritually-based interventions such as meditation, prayer, singing, dancing, yoga, and others for improvement in patients.ConclusionWhile observational data are strong, more randomized controlled trials (RCTs) are needed to establish the role of spiritual interventions and inclusion in neurorehabilitation guidelines towards achieving holistic restoration.</p>","PeriodicalId":19717,"journal":{"name":"NeuroRehabilitation","volume":" ","pages":"406-412"},"PeriodicalIF":1.8,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147390628","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Modified Constraint-Induced Movement Therapy with Trunk Restraint for Upper Extremity Functional Motor Recovery, Balance and Health-Related Quality of Life in Chronic Stroke: A Single-Blinded Randomized Controlled Clinical Trial.","authors":"Abdulrhman M Shahhar, Abdul Rahim Shaik, Vandana Esht, Mohammed Mansour Alshehri, Karthick Balasubramanian, Ramya Ramasamy Sanjeevi, Khadijah Abdulrahman Alfaleh, Weam Okab Alsalem, Wajd A Fathi, Shaima A Alothman","doi":"10.1177/10538135261417372","DOIUrl":"10.1177/10538135261417372","url":null,"abstract":"<p><p>BackgroundThe upper extremity functional recovery remains a major challenge for specialists during post stroke rehabilitation, pertaining to adoption of various compensatory strategies by patients leading to motor redundancy and persistent functional limitations.ObjectivesThe study aimed to evaluate the effectiveness of Patient Tailored-Modified Constraint Induced Movement Therapy (mCIMT) combined with Trunk Restraint (TR) on Upper Extremity motor ability, balance, and health-related quality of life (HR-QOL) in chronic stroke survivors.MethodsIn this patient-blinded trial, 34 voluntary patients with chronic hemiplegia (>6 months post-stroke), aged 45-65 years, with Mini-Mental State Examination (MMSE) scores > 24 having and spasticity graded 1 or 1 + on Modified Ashworth Scale (MAS), were recruited and randomly allocated (1:1) to experimental or control groups. The experimental group received 60 min of Conventional Physical Therapy (CPT) plus 120 min of mCIMT with TR, while the control group received CPT treatment alone, three sessions per week for six consecutive weeks. Outcomes were assessed pre- and post-intervention using the Wolf Motor Function Test (WMFT), Berg Balance Scale (BBS), and Stroke Specific Quality of Life Scale (SS-QOL).ResultsBoth groups demonstrated significant improvements from baseline to post-intervention (<i>p</i> < 0.01) across all outcome measures. However, the experimental group exhibited significantly greater gains in functional ability, as reflected by SS-QOL scores (<i>p</i> < 0.005), compared to the control group.ConclusionEighteen sessions of mCIMT along with TR, delivered over six weeks in combination with CPT, demonstrated significant improvements in all outcomes (WMFT, BBS, and SS-QOL) among chronic stroke patients and is as beneficial to individual rehabilitation as conventional therapy alone.<b>Trial registry name and URL:</b> ClinicalTrails.gov (Registration ID: NCT06692569).</p>","PeriodicalId":19717,"journal":{"name":"NeuroRehabilitation","volume":" ","pages":"413-428"},"PeriodicalIF":1.8,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146106621","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Safety, Feasibility, and Efficacy of the Lumbar Type Hybrid Assistive Limb with Brain Injury-Related Lower Limb Hemiparesis in the Acute Phase: A Pilot Randomized Crossover Trial.","authors":"Gakuto Kitamura, Hiroki Tanaka, Manabu Nankaku, Takayuki Kikuchi, Takumi Kawano, Tomoyo Komatsu, Susumu Miyamoto, Ryosuke Ikeguchi","doi":"10.1177/10538135261423946","DOIUrl":"10.1177/10538135261423946","url":null,"abstract":"<p><p>PurposeThis study aimed to investigate the safety, feasibility, and effect on hemiparetic muscle activity during sit-to-stand exercises using the lumbar type HAL in patients with acute-phase lower limb hemiparesis caused by ischemic stroke, cerebral hemorrhage, or postoperative brain tumor.MethodsThis randomized crossover study included twelve participants (ischemic stroke: 6, cerebral hemorrhage: 2, brain tumor: 4) for part 1, which assessed safety and comfort of sit-to-stand exercise using HAL, and ten participants (ischemic stroke: 4, cerebral hemorrhage: 3, brain tumor: 3) for part 2, which investigated the effect of HAL on muscle activities during sit-to-stand exercises. Participants performed either five sets (part 1) or a single set (part 2) of ten repetitions of sit-to-stand exercises under two conditions: with and without HAL assistance. Outcome included vital signs (blood pressure, heart rate, and percutaneous oxygen saturation), fatigue level in part 1. Muscle activity of bilateral gluteus maximus, biceps femoris, and vastus lateralis during the exercises were assessed in part 2. Outcomes were compared between the two conditions.ResultsThe results demonstrated that there were no significant changes in vital signs and fatigue between two conditions. Furthermore, HAL effectively increased muscle activity (μV) in the hemiparetic side vastus lateralis during the exercises (median, quartile range: 101.1, 55.8-125.9 vs. 79.9, 52.0-103.3, p = 0.03).ConclusionsThese findings suggest that the lumbar type HAL can be safely and feasibly used in patients with acute brain injury-related lower limb paresis, with potential effects on hemiparetic muscle activation. However, these results should be interpreted cautiously as exploratory observations.Registry informationClinical utility of cybernic system for patients with neurological diseases causing who need comprehensive nursing care (Clinical utility of cybernic system for patients with neurological diseases causing who need comprehensive nursing care (CUCSPND)), https://jrct.niph.go.jp/en-latest-detail/jRCTs052180074, jRCTs052180074.The effect of motor therapy using robot suit HAL for the patients with damaged brain (motor therapy using robot suit HAL), https://jrct.niph.go.jp/en-latestdetail/jRCTs052180223, jRCTs052180223.</p>","PeriodicalId":19717,"journal":{"name":"NeuroRehabilitation","volume":" ","pages":"429-439"},"PeriodicalIF":1.8,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147317712","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Characteristics and Trends of Randomized Controlled Trials on Post-Stroke Unilateral Spatial Neglect Rehabilitation: A Systematic Review.","authors":"Sarvenaz Mehrabi, Mohammad R Safaei-Qomi, Cecilia Flores-Sandoval, Jamie L Fleet, Ricardo Viana, Sean Dukelow, Robert Teasell","doi":"10.1177/10538135261420360","DOIUrl":"10.1177/10538135261420360","url":null,"abstract":"<p><p>BackgroundUnilateral spatial neglect (USN) is a common post-stroke deficit that adversely affects activities of daily living and functional independence. Despite advancements in stroke rehabilitation research, USN-specific rehabilitation studies remain relatively limited, contributing to a gap in evidence-based clinical practice.ObjectiveTo characterize randomized controlled trials (RCTs) evaluating post-stroke USN rehabilitation interventions and to provide an overview of the intervention types studied and gaps in the current literature.MethodsSystematic searches of MEDLINE, Embase, Scopus, CINAHL, and PsycINFO were conducted from inception to December 31, 2024. The methodological quality of included RCTs was assessed using the PEDro scale.ResultsA total of 123 RCTs were included, collectively enrolling 3,419 participants. The annual number of trials has remained stable in recent years. The mean sample size was 27.8, and the majority of RCTs (60.2%) were conducted in the subacute phase post-stroke. A total of 44 unique types of intervention were examined across the 123 RCTs. Top-down interventions were evaluated in 49 RCTs (39.8%), while bottom-up therapies were examined in 82 RCTs (66.6%), and pharmacological interventions were used in only 6 studies (4.9%).ConclusionsFuture RCTs on neglect should recruit larger sample sizes, evaluate the efficacy of combined interventions, and implement time-sensitive treatment strategies to maximize gains in the earlier post stroke phase. Additionally, RCTs are needed to specifically address the impact of treatment timing on outcomes, and the long-term effects.</p>","PeriodicalId":19717,"journal":{"name":"NeuroRehabilitation","volume":" ","pages":"371-380"},"PeriodicalIF":1.8,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146227972","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Physiotherapy Interventions for Chronic Stroke: A Systematic Review of Functionality and Quality of Life Outcomes.","authors":"Andrea Razón Karake, Ximena Arantza Valencia Silva, Ángela Hernández Suárez, Teresa Ponce-Lopez, Antonio Ibarra, Yolanda Cruz-Martínez","doi":"10.1177/10538135261420356","DOIUrl":"10.1177/10538135261420356","url":null,"abstract":"<p><p>IntroductionStroke is a neurological alteration which significantly impacts patient's functional abilities and quality of life. Physiotherapy interventions, including therapeutic exercise, robotic therapy, electrotherapy and hydrotherapy, have demonstrated positive effects in addressing the sequelae that persist in the chronic phase.MethodsThis systematic review was registered in PROSPERO (CRD420251102428). Searches were conducted in Cochrane, PubMed, PEDro, Scopus, and Google Scholar. Randomized controlled trials of physiotherapy interventions in chronic stroke were included if they reported outcomes for functionality and quality of life. Methodological quality was assessed using the PEDro scale. 35 articles met the inclusion criteria, of which 18 focused on therapeutic exercise, 8 on robotic therapy, 8 on electrotherapy, and 1 on hydrotherapy, comprising a total of 2,412 patients.ResultsTherapeutic exercise is the most extensively studied intervention in chronic stroke, consistently demonstrating the most favorable outcomes in functionality. Robotic therapy was the second modality showing improvements in functionality, particularly in gait, balance and hand function. Electrotherapy, along with robotic therapy showed the greatest impact on quality of life outcomes. Evidence for hydrotherapy remains limited, with a single trial reporting improvements in balance. Overall, these results suggest that no single physiotherapy modality is superior across all domains, emphasizing the need for a multimodal and individualized approach in chronic stroke rehabilitation.ConclusionPhysiotherapy interventions in chronic stroke show clear benefits, with therapeutic exercise showing the greatest impact on functional recovery and electrotherapy and robotic therapy on quality of life.</p>","PeriodicalId":19717,"journal":{"name":"NeuroRehabilitation","volume":" ","pages":"346-370"},"PeriodicalIF":1.8,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147390608","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}