NeuroRehabilitation最新文献

{"title":"Factors Explaining Limited Daily Hand-use in Individuals with Fair-Good Motor Ability Post-Stroke.","authors":"Yishai Bachar Kirshenboim, Hala Knshiboun Sadran, Jennifer Haddad, Amitai S Oberman, Debbie Rand","doi":"10.1177/10538135261468788","DOIUrl":"10.1177/10538135261468788","url":null,"abstract":"<p><p>BackgroundDespite fair-to-good motor ability of their affected upper extremity, individuals post-stroke often exhibit limited daily hand-use, possibly due to factors beyond the motor impairment.ObjectiveTo identify the factors that best explain the variance in daily hand-use, beyond the motor impairment.MethodsA cross-sectional study included individuals post-stroke with fair-to-good upper extremity motor ability (Fugl-Meyer Assessment>30/66). Hand-use was assessed using the Rating of Everyday Arm-Use in the Community and Home (REACH), which is a self-report questionnaire. We assessed the following factors (tools); proprioception (Thumb Localization Test), executive functions (Color Trails Test; upper extremity dual-task capacity), self-efficacy (Confidence in Arm and Hand Movement scale), and depressive symptoms (Geriatric Depression Scale). Ordinal logistic regression evaluated the contribution of these factors to daily hand-use.ResultsFifty-nine individuals post-stroke (41.7% women, aged 25-88). Despite high motor ability [median (IQR), FMA: 57 (51-63)], daily hand-use was limited, most participants scoring REACH levels 2-3 out of 5. Dual-task capacity and upper-extremity self-efficacy were significant predictors, explaining 45.9% of the variance in hand-use. Each unit increase in dual-task capacity and self-efficacy raised REACH levels by 5.8% and 4.2%, respectively. Proprioceptive deficits and depressive symptoms were not significant predictors.ConclusionsLimited hand-use was explained by reduced dual-task capacity and lower self-efficacy among individuals with fair-good upper-extremity motor ability post-stroke. These factors may represent promising targets for future rehabilitation interventions and should be considered during clinical assessment.</p>","PeriodicalId":19717,"journal":{"name":"NeuroRehabilitation","volume":" ","pages":"331-340"},"PeriodicalIF":2.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148562564","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Improved Flexor Spasticity in Patients with Chronic Stroke Using a Dynamic Wrist-Hand Stretching Device: A Pilot Randomized Controlled Trial.","authors":"Jacob Kim, Justin Kim, Philbert Chen, Phillip Siwoo Kim, Gun Seo Jung, Hyeon-Taek Hong, Kyoung Tae Kim","doi":"10.1177/10538135261465903","DOIUrl":"10.1177/10538135261465903","url":null,"abstract":"<p><p>BackgroundHand and wrist spasticity is a common post-stroke complication that compromises quality of life and functional independence. Because conventional stretching is time-intensive, devices that enable consistent, minimally supervised stretching may improve long-term management. This study evaluated the efficacy of Hand Stretcher^®, a novel dynamic stretching device, for reducing spasticity and improving hand function in patients with chronic stroke.MethodsThirty chronic stroke patients (>12 months post-stroke) with mild upper limb motor weakness (Manual Muscle Testing (MMT) grade3-4) and mild-to-moderate spasticity (Modified Ashworth Scale (MAS) < 3) were enrolled. Participants were randomized to an intervention group (n = 15), which used the dynamic passive stretching device 4 times daily for 15-20 min per session, 7 days a week, over 2 months, and a control group (n = 15). Both groups also received conventional rehabilitation. Outcomes included MAS, MMT, Manual Functional Test, and Brunnstrom stage, assessed at baseline (T0), 1 month (T1), and end of the 2-month intervention period (T2).ResultsOnly the intervention group showed significant reductions in wrist and finger flexor spasticity with no serious adverse events. Manual Functional Test and Brunnstrom stage also improved at T2. No significant changes in wrist or finger extensor strength (MMT) were observed in either group.ConclusionTwo months of intensive use of the Hand Stretcher^® significantly reduced wrist and finger flexor spasticity without concurrent gains in extensor strength in patients with chronic stroke. These preliminary findings support the device's potential as a safe, practical adjunct to conventional rehabilitation in post-stroke recovery.Clinical Trial Registration NumberThe study was registered with the Clinical Research Information Service (CRIS) (KCT 0010204).</p>","PeriodicalId":19717,"journal":{"name":"NeuroRehabilitation","volume":" ","pages":"302-311"},"PeriodicalIF":2.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148376436","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Feasibility of Integrating Music Therapy into Routine Speech-Language Rehabilitation for Post-Stroke Aphasia: A Real-World Outpatient Study.","authors":"Nattapat Taarmat, Benjamas Prathanee, Pornpan Kaenampornpan, Natthasart Unasri, Nichapatr Phutthikhamin","doi":"10.1177/10538135261465902","DOIUrl":"10.1177/10538135261465902","url":null,"abstract":"<p><p>BackgroundEvidence on the feasibility of integrating music therapy into routine post-stroke aphasia rehabilitation in real-world settings remains limited.ObjectiveTo examine the feasibility of integrating a structured music therapy protocol into conventional speech-language therapy for post-stroke aphasia and explore preliminary outcomes.MethodsThis quasi-experimental study was conducted in an outpatient speech-language clinic in Thailand. Participants received standard speech-language therapy or therapy combined with a manualised music therapy protocol. The intervention represents a dose-augmented feasibility design, as the experimental group received increased overall therapeutic contact time. Language performance was assessed using the Thai Adaptation of the Western Aphasia Battery, and anxiety using the State-Trait Anxiety Inventory, Form Y-2. Pre-post changes were examined using descriptive statistics and exploratory analyses, including paired tests for within-group comparisons and independent tests for between-group differences.ResultsThe intervention was feasible, with complete delivery and assessment. Within-group improvements in language performance were observed in both groups, with greater gains in the music therapy-augmented group; however, between-group differences were not statistically significant. Anxiety scores decreased in both groups, with no significant differences. Interpretation of anxiety outcomes is limited by the use of a trait-based measure, which may reflect the limited sensitivity of trait-based measure to short-term changes.ConclusionsIntegrating music therapy into routine speech-language rehabilitation for post-stroke aphasia is feasible in a real-world outpatient setting. Findings should be interpreted as exploratory and reflective of increased therapeutic exposure rather than modality-specific effectiveness. These results inform the design of future dose-matched and methodologically rigorous trials.</p>","PeriodicalId":19717,"journal":{"name":"NeuroRehabilitation","volume":" ","pages":"291-301"},"PeriodicalIF":2.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148405441","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Incomplete Cognitive Assessment in Post-Acute Stroke Rehabilitation: Recovering Clinically Interpretable Relationships from Routine Neuropsychological Data.","authors":"Alejandro García-Rudolph, Rocío Sánchez-Carrión, Katryna Cisek, Thi Nguyet Que Nguyen, Claudia Teixido-Font, Eloy Opisso, Rory O'Connor, Gelu Onose, Gunnar Cedersund","doi":"10.1177/10538135261464181","DOIUrl":"10.1177/10538135261464181","url":null,"abstract":"<p><p>BackgroundIn post-acute stroke rehabilitation, cognitive assessment is clinically important but frequently incomplete. Complete-case analysis excludes much of the sample, reducing representativeness.ObjectivesTo determine whether incomplete routine post-stroke cognitive assessments can still yield clinically interpretable relationships among cognitive, clinical, and contextual variables, and support group-level stratification using a reduced feasible cognitive set.MethodsRetrospective cohort study of adults admitted to post-acute stroke neuro-rehabilitation between 2007 and 2026 with at least one neuropsychological assessment. The baseline cohort included 2654 patients, with 5417 assessments within 6 months available for confirmatory analysis. The 24-subtest baseline battery showed 37.5% to 88.4% missingness. Five representative cognitive measures were selected based on data availability, domain coverage, and within-domain Spearman correlations. Bayesian networks were fitted in the baseline cohort, their stability was assessed by bootstrapping, key dependencies were examined across all available assessments.ResultsStable, bootstrap-supported dependency patterns were recovered and broadly replicated in the confirmatory analysis. Replicated associations linked age and time since injury to verbal learning and naming; stroke subtype to verbal learning, timed orientation/performance, and phonemic fluency. Verbal learning occupied a central position, with additional replicated links to naming, timed orientation/performance, and attentional span. Among the contextual variables, economic status was the only one showing a direct link to a cognitive measure (attentional span). Group-level stratification of verbal learning showed moderate performance (R² = 0.42).ConclusionsIncomplete routine cognitive assessments need not rely on complete-case restriction or score imputation; they can still support clinically meaningful interpretation and group-level stratification in post-acute stroke rehabilitation.</p>","PeriodicalId":19717,"journal":{"name":"NeuroRehabilitation","volume":" ","pages":"268-278"},"PeriodicalIF":2.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148412551","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Pilot Table Tennis-Based Neurorehabilitation Program to Improve Parkinson's Disease Symptoms.","authors":"Antonio Barbera, Matthew Woodward, Isabelle Buard, Stefan Sillau, Ramon Ortega Montes, Jeanne Feuerstein","doi":"10.1177/10538135261468787","DOIUrl":"10.1177/10538135261468787","url":null,"abstract":"<p><p>BackgroundExercise is the only established disease-modifying intervention in Parkinson's disease (PD), and continued exploration of innovative and engaging exercise modalities may further enhance outcomes for individuals living with PD. Table tennis (TT) is a cognitively engaging, task-specific activity integrating visuospatial processing, anticipatory motor planning, and dynamic postural control.ObjectiveTo examine the feasibility, including attendance, retention, and safety, and effects of a 12 week TT-based program, NeuroPong^TM, on motor and non-motor symptoms in individuals with PD.MethodsIn this single-arm pilot study, 30 participants were enrolled and 26 completed 12 weeks of twice-weekly, 2-h TT sessions. The primary outcome was the Movement Disorders Society-Unified Parkinson's Disease Rating Scale Part III (MDS-UPDRS III). Secondary outcomes included the Berg Balance Scale (BBS), Timed Up and Go (TUG), Six-Minute Walk Test (6MWT), Montreal Cognitive Assessment (MoCA) and several patient-reported outcomes. Pre-post comparisons were conducted using paired T-tests.ResultsImprovements were observed in the MDS-UPDRS Part III (mean change -5.73, 95% CI -9.02 to -2.44, p = 0.0014), BBS (mean change +3.08, 95% CI 1.987 to 4.17, p < 0.0001), TUG (mean change -1.04, 95% CI <b>-</b>1.69 to -0.38, p = 0.0032), and 6MWT (mean change 66.77, 95% CI 49.82 to 83.71, p < 0.0001). Self-reported depression decreased (Hospital Anxiety and Depression Scale, HADS-D mean change -1.12, 95% CI -1.97 to -0.26, p = 0.0129). Attendance averaged approximately 90%, and no adverse events were reported. No significant changes were observed in other outcomes.ConclusionsA 12-week TT-based program, NeuroPong™, was feasible and associated with improvement in motor function, balance, walking endurance and self-reported depression in PD. The multidimensional motor and cognitive demands of table tennis may contribute to these observed benefits. Larger randomized controlled trials are warranted.</p>","PeriodicalId":19717,"journal":{"name":"NeuroRehabilitation","volume":" ","pages":"241-248"},"PeriodicalIF":2.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148448494","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Immediate Effects of Exercise and Manual Therapy on Cervico-Mandibular Mobility and Postural Alignment in Children with Spastic Cerebral Palsy: A Randomized Crossover Trial.","authors":"Özge Baykan Çopuroğlu, Baki Umut Tuğay, Muhammet Furkan Vatan","doi":"10.1177/10538135261463254","DOIUrl":"10.1177/10538135261463254","url":null,"abstract":"<p><p>BackgroundSpastic cerebral palsy (CP) commonly impairs cervico-mandibular mobility and motor coordination due to increased muscle tone and altered postural control, potentially affecting head stability and orofacial function.ObjectiveTo compare the immediate effects of exercise- and manual therapy-based interventions on temporomandibular and cervical mobility in children with spastic CP, contrasting active versus passive rehabilitation strategies.MethodsThis single-blind, randomized crossover trial included 52 children with spastic CP (mean age 10.8 ± 2.4 years; GMFCS levels I-IV). Each received one exercise and one manual therapy session in randomized order with a one-week interval. Owing to missed second-week appointments, 44 children completed the exercise session and 48 completed the manual therapy session, resulting in partial crossover completion. Mandibular range of motion (maximal opening, lateral deviation, protrusion), cervical range of motion (flexion, extension, rotation), and craniovertebral angle were assessed immediately before and after each intervention.ResultsBoth interventions produced significant immediate improvements in mandibular and cervical mobility (p < 0.001). Exercise resulted in greater gains in selected active mandibular movements, whereas manual therapy elicited larger improvements in cervical mobility. Craniovertebral angle increased following both interventions, with no significant between-intervention difference, indicating comparable effects on head posture. Effect sizes were moderate to large, and no carryover effects were detected.ConclusionExercise and manual therapy induce modality-specific immediate neuromechanical responses in the cervico-mandibular system in children with spastic CP. These findings reflect short-term rather than long-term effects and suggest both approaches may be considered in individualized pediatric neurorehabilitation planning.</p>","PeriodicalId":19717,"journal":{"name":"NeuroRehabilitation","volume":" ","pages":"218-227"},"PeriodicalIF":2.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148361953","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Quantifying Physical Activity Through Step Count Estimation Across Multiple Wearable Sensor Configurations: A Validation Study in Post-Stroke and Healthy Adults.","authors":"Louise Macq, Stéphanie Dehem, Thierry Lejeune, Virginie Otlet","doi":"10.1177/10538135261463255","DOIUrl":"10.1177/10538135261463255","url":null,"abstract":"<p><p>ObjectiveThe study aimed to identify the most accurate protocol for measuring stride-count in post-stroke and healthy individuals, by comparing different wearable-sensors, their placement and data processing against a gold-standard instrumented treadmill.MethodsEighteen post-stroke and 18 healthy adults walked at multiple speeds on an instrumented treadmill equipped with force plates. Participants wore six ActiGraph accelerometers (wrists, hips, ankles), and pressure insoles. Stride counts from each sensor configuration were estimated using a custom raw-acceleration peak-detection algorithm and the manufacturer's algorithm (ActiLife^®). Accuracy and agreement with the gold standard were assessed across walking speeds and sensor locations using the concordance correlation coefficient (CCC) and linear mixed-effects model.ResultsStride count accuracy was influenced by walking speed across all wearable configurations, improving with gait velocity. Pressure-sensing insoles demonstrated the highest accuracy and agreement with the gold standard in both groups across speeds (CCC = 0.999 for healthy subjects; 0.996 for post-stroke). The custom peak-detection algorithm applied to ankle-worn accelerometers provided accurate and robust stride estimates across speeds (CCC = 0.986 in healthy subjects; 0.990 post-stroke). In contrast, the manufacturer's algorithm consistently misestimated stride counts in both groups. No side-to-side differences were observed for any sensor placement.ConclusionPressure insoles and our custom raw-acceleration algorithm applied to ankle-worn accelerometers yielded the highest stride-count accuracy across walking speeds in both populations.Trial registry name and URLClinicalTrails.gov (Registration ID: NCT06943014).</p>","PeriodicalId":19717,"journal":{"name":"NeuroRehabilitation","volume":" ","pages":"249-267"},"PeriodicalIF":2.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148405439","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cough Assistance Techniques in Adolescents and Young Adults with Neuromuscular Diseases Using Home Noninvasive Ventilatory Support: A Preliminary Cross-Sectional Physiological Study.","authors":"Roberto Vera-Uribe, Edna Karla Ferreira Laurentino, Rodrigo Torres-Castro, Luis Vasconcello-Castillo, Marisol Barros-Poblete, Matías Otto-Yáñez, Javiera Rosales-Fuentes, Jaime Ahumada, Rebeca Paiva Reinero, Guilherme Augusto De Freitas Fregonezi, Jordi Vilaró","doi":"10.1177/10538135261468009","DOIUrl":"10.1177/10538135261468009","url":null,"abstract":"<p><p>BackgroundProgressive respiratory muscle weakness in neuromuscular diseases (NMD) impairs cough effectiveness and increases respiratory morbidity. We compared peak cough flow (PCF) and vital capacity (VC) across airway clearance/cough augmentation techniques in adolescents and young adults using home noninvasive ventilation (NIV).MethodsIn this cross-sectional physiological study, adolescents and young adults with NMD receiving home NIV were evaluated at home. PCF and VC were measured at baseline and immediately after manual assisted cough (MAC), NIV at usual settings, NIV at inspiratory positive airway pressure of 30 cmH2O, air stacking (AS), glossopharyngeal breathing (GPB), and mechanical insufflation-exsufflation (MI-E). Techniques were tested alone and in combination with MAC; the sequence was randomized within participants.ResultsTwenty-four participants (70.8% male; age 17.5 ± 2.4 years) were included. Baseline PCF was 211.2 ± 89.4 L/min. Compared with baseline, PCF increased with MAC, AS, NIV at usual settings, NIV at 30 cmH2O, and MI-E (all p < 0.05), whereas GPB showed no significant change. When combined with MAC, all techniques further increased PCF (e.g., AS + MAC, 306.7 ± 98.4; NIV-30 + MAC, 297.1 ± 94.0 L/min; all p < 0.001), with no between-technique differences. VC increased after AS, MI-E, and NIV (all p < 0.005), but not after GPB.ConclusionsIn adolescents and young adults with NMD using home NIV, AS, NIV, and MI-E improved cough effectiveness and lung volume, and adding MAC produced additional PCF gains.</p>","PeriodicalId":19717,"journal":{"name":"NeuroRehabilitation","volume":" ","pages":"228-240"},"PeriodicalIF":2.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148497858","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Stroke-specific Movement Patterns During Passage Through a Narrow-Opening: A Cross-Sectional Study.","authors":"Daisuke Muroi, Hiroshi Matsui, Takayuki Tomono, Juntaro Sakazaki, Yutaro Saito, Aki Nakazawa, Kentaro Kodama, Takahiro Higuchi","doi":"10.1177/10538135261464177","DOIUrl":"10.1177/10538135261464177","url":null,"abstract":"<p><p>PurposeIndividuals with stroke have difficulty rotating their trunk and adjusting their supporting foot when negotiating spatial constraints. This study aimed to classify movement patterns used when passing through narrow openings and to identify factors associated with stroke-specific patterns.MethodsTwenty-three individuals with stroke (age: 60.7 ± 10.1 years, time after stroke: 15.2 ± 21.1 months, subacute and chronic, independently ambulatory), 23 age-matched community-dwelling adults (61.0 ± 9.7 years), and 12 young adults (25.4 ± 2.5 years) were recruited. Participants walked through openings of various widths. Movement patterns were independently classified by three trained physical therapists, and inter-rater agreement was assessed. Generalized linear mixed models with participants as a random effect were used to examine associations between pattern selection and clinical/environmental factors.ResultsFive passing patterns were identified: (A) pivot, (B-1) early pivot, (B-2) early pivot with reverse trunk rotation, (C) multiple steps, and (D) no-rotation. Inter-rater agreement was substantial (Cohen's <i>κ</i> = .76). Stroke-specific patterns were patterns B-2 and C. The mixed-model analysis showed that B-2 and C were more likely with narrower openings (odds ratio [OR]: .52, 95% confidence interval [CI]: .39-.70; and OR: .18, 95% CI: .11-.32, respectively; both <i>p</i> < .001). TUG performance was not significantly associated with pattern C (OR: 1.22, 95% CI: .99-1.49, <i>p</i> = .056).ConclusionOpening width was associated with stroke-specific pattern selection. Multi-step strategies may reflect increased stability demands, whereas pivot-like strategies may be associated with better mobility. These findings may help clinicians assess movement behaviors in constrained environments.</p>","PeriodicalId":19717,"journal":{"name":"NeuroRehabilitation","volume":" ","pages":"279-290"},"PeriodicalIF":2.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148369416","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Association of Depression, Anxiety, and Quality of Life with Sexual Function in Young-to-Middle-Aged Stroke Patients: A Case-Control Study.","authors":"A Ozakgul, Z Tulek, K Kılıçaslan, S Erden Melikoğlu, H Kaya","doi":"10.1177/10538135261468010","DOIUrl":"10.1177/10538135261468010","url":null,"abstract":"<p><p>BackgroundDespite its impact, sexual health remains a neglected component of rehabilitation for younger stroke patients.AimTo evaluate sexual dysfunction prevelance in stroke patients and examine its association with health-related quality of life and psychological distress.MethodsThis case-control study included 30 stroke patients and 30 matched controls. Data were collected using the Arizona Sexual Experience Scale (ASEX), Stroke-Specific Quality of Life Scale (SSQOL), and Hospital Anxiety and Depression Scale (HADS).ResultsPatients had significantly higher total ASEX scores (19.3 ± 6.6 vs. 13.0 ± 3.1, <i>p</i> < 0.001), and a higher prevalence of dysfunction than controls (<i>p</i> = 0.004), reporting a significant decline in sexual satisfaction (7.5 to 4.1, <i>p</i> < 0.001). Sexual function was significantly associated with the SSQOL Energy, Thinking, and Language domains (<i>p</i> < 0.05), and HADS-Depression (<i>r</i> = 0.450, <i>p</i> = 0.013), but not with functional state.Strengths and LimitationsStrengths include a matched control group. Limitations include a small sample and cross-sectional design, potential selection bias from a high refusal rate, and restricted psychological variance due to clinical exclusions.ConclusionSexual dysfunction represents a multifaceted challenge for young-to-middle-aged stroke patients, appearing more closely linked to perceived quality of life domains (cognitive, energy, emotional well-being) than to motor deficits. Sexual health may be affected even in patients with low physical disability.Clinical ImplicationsRehabilitation should address holistic needs. Healthcare professionals could benefit from incorporating sexual health screenings into routine care, considering the management of fatigue and depressive symptoms to support long-term well-being.</p>","PeriodicalId":19717,"journal":{"name":"NeuroRehabilitation","volume":" ","pages":"321-330"},"PeriodicalIF":2.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13507502/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148579555","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}