Oral oncology最新文献_第2页

Robotic parotidectomy via retroauricular incision: A safe and feasible approach for benign parotid tumors

IF 4 2区医学

Oral oncology Pub Date : 2025-03-24 DOI: 10.1016/j.oraloncology.2025.107253

Ping Han , Faya Liang , Ying Li, Peiliang Lin, Renhui Chen, Xijun Lin, Xiaoming Huang

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Efficacy of pembrolizumab monotherapy for advanced gingival malignant melanoma: A case report

IF 4 2区医学

Oral oncology Pub Date : 2025-03-22 DOI: 10.1016/j.oraloncology.2025.107267

Jie Li , Chong-tao Xu , Wei Wu

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Sclerosing mucoepidermoid carcinoma with eosinophilia of the thyroid: Clinicopathological characterization and whole-exome sequencing insights

IF 4 2区医学

Oral oncology Pub Date : 2025-03-19 DOI: 10.1016/j.oraloncology.2025.107259

Nan Song , Xianglei He , Ting Duan , Luanxue Yu , Jiawei Ming , Jiawei Yu , Zhenying Guo

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Commentary on, “Post-treatment monitoring of surgically treated oropharyngeal squamous cell carcinoma patients using human papillomavirus cell-free DNA”

IF 4 2区医学

Oral oncology Pub Date : 2025-03-17 DOI: 10.1016/j.oraloncology.2025.107257

Gnanaprakash Jeyaraj

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AI-driven histopathologic insights in HPV-positive head and neck squamous cell carcinomas

IF 4 2区医学

Oral oncology Pub Date : 2025-03-17 DOI: 10.1016/j.oraloncology.2025.107261

Carlos M. Ardila , Pradeep Kumar Yadalam

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Commentary on, “Thyroid volumes after intensity-modulated radiotherapy as predictors of radiation-induced hypothyroidism in nasopharyngeal carcinoma: A retrospective study”

IF 4 2区医学

Oral oncology Pub Date : 2025-03-17 DOI: 10.1016/j.oraloncology.2025.107256

Gnanaprakash Jeyaraj

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Letter to Editor on, “Induction chemotherapy and concurrent chemoradiotherapy with cisplatin for T4 nasoethmoidal squamous cell carcinoma: The value of paclitaxel, carboplatin and cetuximab (PCE)”

IF 4 2区医学

Oral oncology Pub Date : 2025-03-17 DOI: 10.1016/j.oraloncology.2025.107255

Gnanaprakash Jeyaraj

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Oral HPV incidence and risk factors for acquisition

IF 4 2区医学

Oral oncology Pub Date : 2025-03-17 DOI: 10.1016/j.oraloncology.2025.107249

Gypsyamber DSouza , Sakshi Tewari , Tanya Troy , Paige Bleyer , Mabel Korley , Jennafer Kwait , Ken Ho , Maura Gillison , Dorothy Wiley , Jason Lazar , Kathleen M. Weber , Howard Strickler , Cecile D Lahiri , Frank Palella , Linda Struijk , Carole Fakhry

{"title":"Oral HPV incidence and risk factors for acquisition","authors":"Gypsyamber DSouza , Sakshi Tewari , Tanya Troy , Paige Bleyer , Mabel Korley , Jennafer Kwait , Ken Ho , Maura Gillison , Dorothy Wiley , Jason Lazar , Kathleen M. Weber , Howard Strickler , Cecile D Lahiri , Frank Palella , Linda Struijk , Carole Fakhry","doi":"10.1016/j.oraloncology.2025.107249","DOIUrl":"10.1016/j.oraloncology.2025.107249","url":null,"abstract":"<div><h3>Background</h3><div>We evaluated incidence of oral HPV infection, which precedes HPV-related oropharynx cancer.</div></div><div><h3>Methods</h3><div>In this prospective multicenter cohort of participants with HIV and demographically similar participants without HIV, oral rinse and gargle samples were collected every 6–12 months and tested for 35 HPV types (anyHPV), 13 of which were oncogenic (oncHPV). Kaplan Meier and Cox regression were used for incidence curves and clustered risk factor hazard ratios. Logistic regression was used to determine relative odds of same infection at next visit.</div></div><div><h3>Results</h3><div>The 1587 participants had a median follow-up of 3.67 years, 422 had 708 incident type-specific oral HPV detected. The most common oncHPV was HPV16 [incidence rate = 7.8 per 1000 person-years (95 %CI 5.8–10.6)]. At 5 years, the cumulative incidence of anyHPV, oncHPV and HPV16 was 34.9 % (95 %CI = 31.9 %, 38.3 %), 17.1% (95 %CI = 14.8 %, 19.8 %) and 4.0 % (95 %CI = 2.9, 5.6 %), respectively. Risk of incident oral HPV infection was independently associated with a higher number of oral sex partners, current smoking, younger age, prevalent oral anyHPV, living with HIV and lower CD4 counts. Prevalent oncHPV at baseline had greater odds of being re-detected at subsequent visits than an incident oncHPV detected for the first-time at a later visit. Detection of oral HPV type at one visit was associated with highly elevated odds of detecting that same type-specific infection at the next visit (OR > 100).</div></div><div><h3>Conclusion</h3><div>Cumulative incidence of oral HPV is increased among PLWH and with prevalent oral HPV, represents a mix of new and intermittently detected infections, and is higher among those with repeated detection of oral HPV.</div></div>","PeriodicalId":19716,"journal":{"name":"Oral oncology","volume":"163 ","pages":"Article 107249"},"PeriodicalIF":4.0,"publicationDate":"2025-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143642416","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Two-year follow-up of a rare primary branchial cleft carcinoma: Case analysis and management insights

IF 4 2区医学

Oral oncology Pub Date : 2025-03-13 DOI: 10.1016/j.oraloncology.2025.107215

Jiayu Shen , Xin Wei , Zhiyan Wu , Xi Li , Sichen Han , Xinliang Duan , Yao Yuan , Peng Liu , Zilin Wang

引用次数: 0

Changes in unmet needs after treatment for head and neck cancers – A prospective longitudinal cohort study

IF 4 2区医学

Oral oncology Pub Date : 2025-03-12 DOI: 10.1016/j.oraloncology.2025.107250

John Mohan Mathew , Ionut Busca , Zeynep Baskurt , Meredith Giuliani , Naa Kwarley Quartey , Jennifer Jones , Maureen McQuestion , Janet Papadakos , John Waldron , Jessica Weiss , Jolie Ringash

{"title":"Changes in unmet needs after treatment for head and neck cancers – A prospective longitudinal cohort study","authors":"John Mohan Mathew , Ionut Busca , Zeynep Baskurt , Meredith Giuliani , Naa Kwarley Quartey , Jennifer Jones , Maureen McQuestion , Janet Papadakos , John Waldron , Jessica Weiss , Jolie Ringash","doi":"10.1016/j.oraloncology.2025.107250","DOIUrl":"10.1016/j.oraloncology.2025.107250","url":null,"abstract":"<div><h3>Objectives</h3><div>This study aimed to assess changes in unmet needs among patients with head and neck cancer (HNC) from pre-treatment to two years post-treatment and identify factors associated with higher levels of unmet needs.</div></div><div><h3>Materials & Methods</h3><div>Patients treated for HNC at Princess Margaret Cancer Centre between June 2016 and February 2019 were recruited. Participants completed the Cancer Survivors’ Unmet Needs Measure Questionnaire (CaSUN), the Functional Assessment of Cancer Therapy − Head and Neck (FACT-HN) questionnaire, and the EuroQol EQ-5D-5L utility and Visual Analog Scale (EQ-5D-5L and VAS) pre-treatment and at 3, 6, 12, and 24-months post-treatment.</div></div><div><h3>Results</h3><div>Among 332 eligible patients approached, 197 were included. Significant reductions in number of unmet needs were observed between baseline and all follow-ups: 48 % fall at 3 months (p < 0.001), 39 % at 6 (p = 0.001), 54 % at 12 (p < 0.001), and 59 % at 24 months (p < 0.001). Higher education (p = 0.018, RR 1.88 [95 % CI 1.1–3.1]) and lower baseline FACT-HN & EQ-5D-5L VAS scores (p < 0.001, RR 0.98 [95 % CI 0.96–0.99] & p = 0.02, RR 0.99 [95 % CI 0.97–1 respectively]) were associated with higher unmet needs pre-treatment. Younger age (p = 0.041, RR 0.95 [95 %C I 0.9–1]) and lower baseline FACT-HN scores (p = 0.028, RR 0.97 [95 % CI 0.95–1]) were associated with higher unmet needs at 24 months.</div></div><div><h3>Conclusions</h3><div>Patients with HNC experience unmet needs, but the number declines from pre-treatment to two years post-treatment. Younger age, higher educational level, lower baseline FACT HN and EQ-5D-5L scores were associated with higher levels of unmet needs at various follow-up stages.</div></div>","PeriodicalId":19716,"journal":{"name":"Oral oncology","volume":"163 ","pages":"Article 107250"},"PeriodicalIF":4.0,"publicationDate":"2025-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143610697","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0