Proceedings IEEE International Symposium on Bio-Informatics and Biomedical Engineering最新文献_第4页

Mining residue contacts in proteins using local structure predictions 利用局部结构预测挖掘蛋白质中的残馀接触

Proceedings IEEE International Symposium on Bio-Informatics and Biomedical Engineering Pub Date : 2000-11-08 DOI: 10.1109/BIBE.2000.889604

Mohammed J. Zaki, Shanrong Jin, C. Bystroff

引用次数: 57

Phylogenetic tree reconstruction using self-adaptive genetic algorithm 基于自适应遗传算法的系统发育树重建

Proceedings IEEE International Symposium on Bio-Informatics and Biomedical Engineering Pub Date : 2000-11-08 DOI: 10.1109/BIBE.2000.889599

A. Skourikhine

引用次数: 17

Hierarchical control for artificial hearts 人工心脏的层次控制

Proceedings IEEE International Symposium on Bio-Informatics and Biomedical Engineering Pub Date : 2000-11-08 DOI: 10.1109/BIBE.2000.889631

J. Boston, J. Antaki, M. Simaan

引用次数: 4

A divide and conquer deformable contour method 分而治之的可变形轮廓法

Proceedings IEEE International Symposium on Bio-Informatics and Biomedical Engineering Pub Date : 2000-11-08 DOI: 10.1109/BIBE.2000.889628

Xun Wang, William G. Wee

{"title":"A divide and conquer deformable contour method","authors":"Xun Wang, William G. Wee","doi":"10.1109/BIBE.2000.889628","DOIUrl":"https://doi.org/10.1109/BIBE.2000.889628","url":null,"abstract":"A divide and conquer strategy in the deformable contour method is presented. An initial inside closed contour is divided into segments, and these segments are allowed to deform separately preserving segments' connectivity. A deformable contour algorithm is adapted to each contour segment movement. A maximum area threshold, A/sub max/, is used to stop these outward contour segment marchings. Clear and blur contour points are then identified, and the whole contour is repartitioned into clear, blur, and gap segments. A bi-directional searching method is then recursively applied to each, blur, or gap segment until a final contour is sought. At this point, a search for contour within contour segment is undertaken so that the inner most contour can be searched. At all times, a global snake type performance index is used to find each local contour segment. Experiments have shown that the method has the capability of moving a contour into the neighboring region of the solution contour by overcoming all the above inhomogeneous interior, and of adapting each contour segment searching operation to different local difficulties, through a contour partition and repartition scheme in searching for a final solution. These experiments include ultrasound images of pig heart, MRI brain images, and MRI knee images having complex shapes and/or with gaps, inhomogeneous interior and contour region brightness distributions.","PeriodicalId":196846,"journal":{"name":"Proceedings IEEE International Symposium on Bio-Informatics and Biomedical Engineering","volume":"93 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2000-11-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124530564","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Pencil beam scanning: a dynamical approach to proton therapy 铅笔束扫描:质子治疗的动态方法

Proceedings IEEE International Symposium on Bio-Informatics and Biomedical Engineering Pub Date : 2000-11-08 DOI: 10.1109/BIBE.2000.889630

R. Sepulchre, M. Gérard, B. Marchand, D. Prieels

引用次数: 1

Futuristic combinatorial analog computing systems: the DNA synchro solution 未来组合模拟计算系统:DNA同步解决方案

Proceedings IEEE International Symposium on Bio-Informatics and Biomedical Engineering Pub Date : 2000-11-08 DOI: 10.1109/BIBE.2000.889600

E. Hibbs

引用次数: 0

A digital retina-like low level vision processor 一种类似视网膜的数字低电平视觉处理器

Proceedings IEEE International Symposium on Bio-Informatics and Biomedical Engineering Pub Date : 2000-11-08 DOI: 10.1109/BIBE.2000.889616

J. S. Mertoguno, N. Bourbakis

引用次数: 6

Gene mapping by haplotype pattern mining 单倍型模式挖掘的基因定位

Proceedings IEEE International Symposium on Bio-Informatics and Biomedical Engineering Pub Date : 2000-11-08 DOI: 10.1109/BIBE.2000.889596

Hannu (TT) Toivonen, P. Onkamo, Kari Vasko, V. Ollikainen, P. Sevon, H. Mannila, J. Kere

引用次数: 14

Feedback analysis of calcium homeostasis and parturient paresis 钙稳态与分娩轻瘫的反馈分析

Proceedings IEEE International Symposium on Bio-Informatics and Biomedical Engineering Pub Date : 2000-11-08 DOI: 10.1109/BIBE.2000.889629

H. El-Samad, M. Khammash

{"title":"Feedback analysis of calcium homeostasis and parturient paresis","authors":"H. El-Samad, M. Khammash","doi":"10.1109/BIBE.2000.889629","DOIUrl":"https://doi.org/10.1109/BIBE.2000.889629","url":null,"abstract":"In the technological and engineering sciences feedback control methods have been studied and applied extensively to man-made systems. Recently, there has been an increasing interest as to the applicability of feedback and control theory to the life sciences. In a previous paper (H. El-Samad et al., \"Calcium homeostasis: a feedback control point of view,\" Proceedings of the 2000 American Control Conference, Chicago, Il, June 2000), the applicability of control theory to the analysis of calcium homeostasis was investigated. A mathematical model for this homeostatic mechanism was derived. Here, the authors provide an overview of this model, and then use it to study a pathological condition of the calcium regulatory mechanism in dairy cows. The clinical condition studied is referred to as parturient paresis (milk fever) and is the result of severe hypocalcemia at the time of parturition. The authors show that their mathematical feedback model for calcium homeostasis exhibits dynamic behavior that can correspond to milk fever. They then present a rigorous mathematical result that guarantees the presence of milk fever-like dynamics for a range of model parameters.","PeriodicalId":196846,"journal":{"name":"Proceedings IEEE International Symposium on Bio-Informatics and Biomedical Engineering","volume":"22 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2000-11-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125333676","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A schema-based approach to building a bioinformatics database federation 基于模式的生物信息学数据库联盟构建方法

Proceedings IEEE International Symposium on Bio-Informatics and Biomedical Engineering Pub Date : 2000-11-08 DOI: 10.1109/BIBE.2000.889584

G. Kemp, N. Angelopoulos, P. Gray

{"title":"A schema-based approach to building a bioinformatics database federation","authors":"G. Kemp, N. Angelopoulos, P. Gray","doi":"10.1109/BIBE.2000.889584","DOIUrl":"https://doi.org/10.1109/BIBE.2000.889584","url":null,"abstract":"Developments in our ability to integrate and analyse the data held in existing heterogeneous data resources can lead to an increase in our understanding of biological function at all levels. However, supporting ad-hoc queries across multiple data resources and correlating the data retrieved from these is still difficult. To address this, we are building a mediator based on the functional data model database, P/FDM, which integrates access to heterogeneous, distributed biological databases, while making use of existing search engines and indexes, without infringing on the autonomy of the underlying databases. Central to our design philosophy is the use of schemas. We have adopted a federated architecture with a five-level schema, arising from the use of the ANSI-SPARC three-level schema to describe both the existing autonomous data resources and the mediator itself. We describe the use of mapping functions and list comprehensions in query splitting, producing execution plans, code generation and result fusion. We give an example of cross-database querying involving data held locally in P/FDM systems and external data in the Sequence Retrieval System (SRS).","PeriodicalId":196846,"journal":{"name":"Proceedings IEEE International Symposium on Bio-Informatics and Biomedical Engineering","volume":"27 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2000-11-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"120845832","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 30