Proceedings IEEE International Symposium on Bio-Informatics and Biomedical Engineering最新文献

Simulation studies on the dynamics of diabetes mellitus 糖尿病动力学的模拟研究

Proceedings IEEE International Symposium on Bio-Informatics and Biomedical Engineering Pub Date : 2000-11-08 DOI: 10.1109/BIBE.2000.889612

F. Erzen, G. Birol, A. Çinar

引用次数: 20

A global description of medical image with high precision 一种高精度的医学图像全局描述

Proceedings IEEE International Symposium on Bio-Informatics and Biomedical Engineering Pub Date : 2000-11-08 DOI: 10.1109/BIBE.2000.889620

R. Chbeir, Franck Favetta

{"title":"A global description of medical image with high precision","authors":"R. Chbeir, Franck Favetta","doi":"10.1109/BIBE.2000.889620","DOIUrl":"https://doi.org/10.1109/BIBE.2000.889620","url":null,"abstract":"Medical Imaging suffers from different problems. This paper explores the authors' solution that aims to provide efficient retrieval of medical imaging. Depending on the user, the same image can be described through different views. In essence, an image can be described on the basis of either low-level properties, such as texture or color; context, such as date of acquisition or author; or semantic content, such as real-world objects and relations. The authors' approach consists of providing a global description solution capable of integrating different dimensions (or views) of a medical image. The description problem of medical images during both storage and retrieval processes is studied. Few proposed solutions take into consideration the heterogeneity of user competence (physician, researcher, student, etc.) and the necessity of a high expressive power for medical imaging description. For example, spatial content in terms of relationships in surgical or radiation therapy of brain tumors is very decisive because the location of a tumor has profound implications on a therapeutic decision. Visual solutions are recommended and are the most appropriated for non computer-scientist users. However, current visual languages suffer from several problems, especially ambiguities generated by the user and/or the system at different levels of image description, imprecision and no respect of the integrity of spatial relations. This framework exposes the authors' solution showing how this problematic can be resolved. An implementation has been realized to prove their proposition.","PeriodicalId":196846,"journal":{"name":"Proceedings IEEE International Symposium on Bio-Informatics and Biomedical Engineering","volume":"41 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2000-11-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123876964","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 17

A compiler to transfer controlled vocabularies and ontologies represented in an object-oriented programming language into text mark-up languages 一种编译器，用于将用面向对象编程语言表示的受控词汇表和本体转换为文本标记语言

Proceedings IEEE International Symposium on Bio-Informatics and Biomedical Engineering Pub Date : 2000-11-08 DOI: 10.1109/BIBE.2000.889593

J. Reich

引用次数: 0

Kleisli: its exchange format, supporting tools, and an application in protein interaction extraction Kleisli:其交换格式，支持工具，以及在蛋白质相互作用提取中的应用

Proceedings IEEE International Symposium on Bio-Informatics and Biomedical Engineering Pub Date : 2000-11-08 DOI: 10.1109/BIBE.2000.889585

L. Wong

引用次数: 23

A framework of automated reconstruction of microbial metabolic pathways 微生物代谢途径的自动重建框架

Proceedings IEEE International Symposium on Bio-Informatics and Biomedical Engineering Pub Date : 2000-11-08 DOI: 10.1109/BIBE.2000.889606

A. Bansal

引用次数: 7

Global optimization approaches to MEG source localization MEG源定位的全局优化方法

Proceedings IEEE International Symposium on Bio-Informatics and Biomedical Engineering Pub Date : 2000-11-08 DOI: 10.1109/BIBE.2000.889611

T. Jiang, Xiaodong Li, F. Kruggel

引用次数: 4

The Prometheus taxonomic database 普罗米修斯分类数据库

Proceedings IEEE International Symposium on Bio-Informatics and Biomedical Engineering Pub Date : 2000-11-08 DOI: 10.1109/BIBE.2000.889590

C. Raguenaud, J. Kennedy, P. Barclay

{"title":"The Prometheus taxonomic database","authors":"C. Raguenaud, J. Kennedy, P. Barclay","doi":"10.1109/BIBE.2000.889590","DOIUrl":"https://doi.org/10.1109/BIBE.2000.889590","url":null,"abstract":"M.R. Pullen et al. (2000) have designed a new model of plant taxonomy (called Prometheus); it supports multiple overlapping classifications, and distinguishes the process of naming from classifying. The concepts identified in this taxonomic model necessitated the design of a new database model - the Prometheus Object-Oriented Model (POOM) - to represent and manipulate the data. POOM is an extended object-oriented model which emphasises relationships, thereby providing graph behaviour in an object-oriented database and providing an expressive means of defining relationships between objects. Additionally, the Object Query Language (OQL) is extended to the Prometheus Object-Oriented Language (POOL) in order to provide unified querying of object-oriented graph structures. This paper presents a taxonomic database system designed in terms of the concepts offered by POOM. Through examples we show how the representation of the semantics and processes of taxonomy, not possible using existing data models, can be supported. Example POOL queries highlight the need for the extended features for manipulating relationships, graph structures and complex objects such as are found in taxonomies.","PeriodicalId":196846,"journal":{"name":"Proceedings IEEE International Symposium on Bio-Informatics and Biomedical Engineering","volume":"35 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2000-11-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124830417","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 12

Clustering 3D-structures of small amino acid chains for detecting dependences from their sequential context in proteins 聚类的小氨基酸链的3d结构检测依赖于他们的顺序上下文在蛋白质

Proceedings IEEE International Symposium on Bio-Informatics and Biomedical Engineering Pub Date : 2000-11-08 DOI: 10.1109/BIBE.2000.889588

Alexander Hinneburg, D. Keim, W. Brandt

{"title":"Clustering 3D-structures of small amino acid chains for detecting dependences from their sequential context in proteins","authors":"Alexander Hinneburg, D. Keim, W. Brandt","doi":"10.1109/BIBE.2000.889588","DOIUrl":"https://doi.org/10.1109/BIBE.2000.889588","url":null,"abstract":"In the past, a good number of rotamer libraries have been published, which allow a deeper understanding of the conformational behavior of amino acid residues in proteins. Since the number of available high-resolution X-ray protein structures has grown significantly over the last years, a more comprehensive analysis of the conformational behavior is possible today. In this paper, we present a method to compile a new class of rotamer libraries for detecting interesting relationships between residue conformations and their sequential context in proteins. The method is based on a new algorithm for clustering residue conformations. To demonstrate the effectiveness of our method, we apply our algorithm to a library consisting of all 8000 tripeptide fragments formed by the 20 native amino acids. The analysis shows some very interesting new results, namely that some specific tripeptide fragments show some unexpected conformation of residues instead of the highly preferred conformation. In the neighborhood of two asparagine residues, for example, threonine avoids the conformation which is most likely to occur otherwise. The new insights obtained by the analysis are important in understanding the formation and prediction of secondary structure elements and will consequently be crucial for improving the state-of-the-art of protein folding.","PeriodicalId":196846,"journal":{"name":"Proceedings IEEE International Symposium on Bio-Informatics and Biomedical Engineering","volume":"3 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2000-11-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129577827","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Wearable computer as a multi-parametric monitor for physiological signals 作为生理信号多参数监测器的可穿戴计算机

Proceedings IEEE International Symposium on Bio-Informatics and Biomedical Engineering Pub Date : 2000-11-08 DOI: 10.1109/BIBE.2000.889613

J. C. D. Conway, C. Coelho, D. Silva, A. O. Fernandes, L. C. G. Andrade, H. Carvalho

引用次数: 10

Genomic signature is preserved in short DNA fragments 基因组特征保存在短的DNA片段中

Proceedings IEEE International Symposium on Bio-Informatics and Biomedical Engineering Pub Date : 2000-11-08 DOI: 10.1109/BIBE.2000.889603

P. Deschavanne, A. Giron, Joseph Vilain, Christine Dufraigne, B. Fertil

引用次数: 53