Paediatrica Indonesiana最新文献

Optic nerve sheath diameter and severity of central nervous infection 视神经鞘直径与中枢神经感染的严重程度

IF 0.2

Paediatrica Indonesiana Pub Date : 2023-11-13 DOI: 10.14238/pi63.5.2023.411-7

Anggun Puspita Dewi, Dzulfikar Djalil Lukmanul Hakim, Sri E Rahayuningsih, N. A. Risan, R. Ghrahani, R. Adrizain

{"title":"Optic nerve sheath diameter and severity of central nervous infection","authors":"Anggun Puspita Dewi, Dzulfikar Djalil Lukmanul Hakim, Sri E Rahayuningsih, N. A. Risan, R. Ghrahani, R. Adrizain","doi":"10.14238/pi63.5.2023.411-7","DOIUrl":"https://doi.org/10.14238/pi63.5.2023.411-7","url":null,"abstract":"Background Central nervous system (CNS) infection affects the brain, and can cause cerebral edema, increased intracranial pressure (ICP), cerebral herniation, and death. Measurement of the optic nerve sheath diameter (ONSD) by ultrasound is a new, non–invasive examination to predict ICP, with high sensitivity and specificity.Objective To analyze for a possible association between ONSD measured by ultrasonographic examination and severity of CNS infection. Methods This cross–sectional study was performed in the Pediatric Department of Hasan Sadikin Hospital, Bandung, West Java. Subjects were chosen by consecutive sampling. We measured ONSD, examined clinical manifestations, as well as performed a cerebrospinal fluid (CSF) study and imaging of CNS infection. Data analysis was done by paired T–test and one–way ANOVA, followed by Tukey test on significant variables. Results Subjects consisted of 32 children with CNS infection. The most common clinical symptoms were fever, decreased consciousness, and nuchal rigidity. Bivariate analysis revealed strong positive associations between ONSD and Glasgow Coma Scale (GCS), increased protein levels in CSF, and type of CNS infection. Conclusion Larger ONSD is significantly associated with lower GCS, increases CSF protein, and particular CNS infections. The ONSD is also associated with meningitis tuberculosis grade III, with a higher mean ONSD of both eyes compares to other CNS infections. Hence, the higher the ONSD, the more severe the degree of CNS infection.","PeriodicalId":19660,"journal":{"name":"Paediatrica Indonesiana","volume":"27 3","pages":""},"PeriodicalIF":0.2,"publicationDate":"2023-11-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139278202","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Fetus in fetu - the included twin/entrapped twin: a case report 胎儿--被包裹的双胞胎/被包裹的双胞胎：病例报告

IF 0.2

Paediatrica Indonesiana Pub Date : 2023-11-13 DOI: 10.14238/pi63.5.2023.418-24

Sanjay M. Khaladkar, Venkata Sai Mani Deepak Koganti, Vikas Leelavati Balasaheb Jadhav, Rachit Khandelwal, P. Lamghare

引用次数: 0

Quality of life of children with acute lymphoblastic leukemia 急性淋巴细胞白血病患儿的生活质量

IF 0.2

Paediatrica Indonesiana Pub Date : 2023-11-13 DOI: 10.14238/pi63.5.2023.405-10

Siti Arifah, Renu Pookboonmee, Autchareeya Patoomwan, Prasong Kittidumrongsuk, Mia Ratwita Andarsini

{"title":"Quality of life of children with acute lymphoblastic leukemia","authors":"Siti Arifah, Renu Pookboonmee, Autchareeya Patoomwan, Prasong Kittidumrongsuk, Mia Ratwita Andarsini","doi":"10.14238/pi63.5.2023.405-10","DOIUrl":"https://doi.org/10.14238/pi63.5.2023.405-10","url":null,"abstract":"Background Acute lymphoblastic leukemia (ALL) is the most common cancer in children worldwide, which requires long treatment. This condition and its subsequent treatment change the body's physiology, reducing children’s quality of life. Objective To describe the quality of life in children with acute lymphoblastic leukemia in Java, Indonesia. Methods This descriptive study with a cross-sectional approach included parents who had children with ALL at three referral hospitals in Java, Indonesia, between January 2021 and May 2022. We recruited 188 mothers or fathers who accompanied their children for follow-up visits or hospitalization. Children’s quality of life as the primary outcome was evaluated by parent proxy using the PedsQL 3.0 cancer module. Results Most parents were mothers (81.9%); parents’ ages ranged from 22 to 59 years. The mean age of children was 7.63 (SD 3.85) years, with 63.3% boys and 147 (78.2%) treated in maintenance phase during the study. The mean overall children’s QoL score was 84.37 and it classified as high (73.9% of subjects), no children had very low QoL. The lowest mean sub-scale QoL score was in procedural anxiety (72.25), whereas the highest sub-scale score was in communication (91.56). Conclusion There is an improvement in QoL of children with ALL in Indonesia. However, the procedural anxiety sub-scale requires more interventions to reduce anxiety and alleviate pain during invasive procedures.","PeriodicalId":19660,"journal":{"name":"Paediatrica Indonesiana","volume":"71 6","pages":""},"PeriodicalIF":0.2,"publicationDate":"2023-11-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139278178","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Quality of life in children with chronic kidney disease 慢性肾病儿童的生活质量

IF 0.2

Paediatrica Indonesiana Pub Date : 2023-11-08 DOI: 10.14238/pi63.5.2023.395-404

Ari Fibrianto, Hertanti Indah Lestari, Yudianita Kesuma, Moretta Damayanti, Eka Intan Fitriana, Rismarini Rismarini

{"title":"Quality of life in children with chronic kidney disease","authors":"Ari Fibrianto, Hertanti Indah Lestari, Yudianita Kesuma, Moretta Damayanti, Eka Intan Fitriana, Rismarini Rismarini","doi":"10.14238/pi63.5.2023.395-404","DOIUrl":"https://doi.org/10.14238/pi63.5.2023.395-404","url":null,"abstract":"Background Chronic kidney disease (CKD) has become a global burden on the healthcare system and significantly impacts the quality of life of children with the condition. Objective To assess quality of life in children with CKD as well as its relationship with sociodemographic, medical, and psychosocial factors. Methods This cross-sectional analytic study was conducted from June to November 2021 at Dr. Moh Hoesin Hospital, Palembang. Children with CKD aged 2–18 years were included by consecutive sampling. Parents and patients were asked to complete the PedsQL™ generic score scale version 4.0 questionnaire. Results We assessed quality of life in 112 children with CKD from parents’ and children’s reports in the PedsQL™ questionnaire. Physical and emotional parameters had the lowest scores. Based on parental reports, quality of life was significantly associated with disease severity (P=0.002), behavioral disorders (P=0.007), and sleep disturbances (P=0.001). Based on the children’s reports, the factors significantly associated with quality of life were anemia (P=0.044), sleep disturbances (P=0.024), and behavioral disorders (P=0.002). Almost one-third of children with CKD had general impairment of quality of life, both from parental reports (32.1%) and children’s reports (33.0%). Conclusion Disease severity, anemia, sleep disturbance, and behavioral disorders were all associated with poorer quality of life in children with CKD.","PeriodicalId":19660,"journal":{"name":"Paediatrica Indonesiana","volume":"144 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2023-11-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139283069","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Preoperative hypoalbuminemia and severe acute malnutrition as prognostic factors for postoperative complications in major abdominal surgery: A single-center retrospective study 术前低白蛋白血症和严重急性营养不良是腹部大手术术后并发症的预后因素：单中心回顾性研究

IF 0.2

Paediatrica Indonesiana Pub Date : 2023-11-06 DOI: 10.14238/pi63.5.2023.389-94

Lestarina Veronica Haloho, N. Nurnaningsih, Endy Paryanto

{"title":"Preoperative hypoalbuminemia and severe acute malnutrition as prognostic factors for postoperative complications in major abdominal surgery: A single-center retrospective study","authors":"Lestarina Veronica Haloho, N. Nurnaningsih, Endy Paryanto","doi":"10.14238/pi63.5.2023.389-94","DOIUrl":"https://doi.org/10.14238/pi63.5.2023.389-94","url":null,"abstract":"Background Hypoalbuminemia and malnutrition are common factors that can adversely affect wound healing and increase the risk of postoperative infections. Improvements in albumin and preoperative nutritional status are expected to reduce the incidence of complications following postoperative abdominal surgery. Objective To evaluate the roles of hypoalbuminemia and poor preoperative nutritional status as prognostic factors for postoperative complications in pediatric patients undergoing major abdominal surgery. Methods This retrospective cohort study included pediatric patients aged 1 month to 18 years who underwent major abdominal surgery and were treated in the pediatric intensive care unit (PICU) of Dr. Sardjito Hospital between January 1, 2017 to December 31, 2021. The primary was the incidence of postoperative complications within 14 days after the surgical procedure. Results Out of the 201 pediatric patients included in the study, 54.7% were male. We observed an overall complication rate of 21.3% following abdominal surgery, with sepsis as the most frequent, affecting 14.9% of the cases. On average, postoperative complications occurred approximately 10.9 days after surgery. Multivariate analysis identified severe acute malnutrition [hazard ratio (HR) 2.09 (95%CI 1.01 to 4.33); P=0.047], preoperative hypoalbuminemia of >2.5 to 3.0 g/dL [HR 3.64 (95%CI 1.57 to 8.41); P=0.003], preoperative hypoalbuminemia ?2.5 g/dL [HR 3.1 (95%CI 1.11 to 8.64); P=0.03], and age <1 year [HR 2.16 (95%CI 1.09 to 4.11); P=0.026] as significant prognostic factors for post-abdominal surgery complications in children. Conclusion Preoperative severe acute malnutrition and preoperative hypoalbuminemia of ?3 g/dL are significant prognostic factors for the occurrence of postoperative complications in pediatric patients undergoing abdominal surgery. Infants less than one year of age are at increased risk of such complications.","PeriodicalId":19660,"journal":{"name":"Paediatrica Indonesiana","volume":"56 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2023-11-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139288119","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Cumulative cyclophosphamide dose and serum anti-Mullerian hormone levels in adolescent cancer survivors in Indonesia 印度尼西亚青少年癌症幸存者的环磷酰胺累积剂量和血清抗穆勒氏管激素水平

IF 0.2

Paediatrica Indonesiana Pub Date : 2023-11-03 DOI: 10.14238/pi63.5.2023.376-82

Sri Mulatsih, S. Ayuandari, Naafi Rizqi Rahmawati, Rizki Oktasari, Agung Dewanto

{"title":"Cumulative cyclophosphamide dose and serum anti-Mullerian hormone levels in adolescent cancer survivors in Indonesia","authors":"Sri Mulatsih, S. Ayuandari, Naafi Rizqi Rahmawati, Rizki Oktasari, Agung Dewanto","doi":"10.14238/pi63.5.2023.376-82","DOIUrl":"https://doi.org/10.14238/pi63.5.2023.376-82","url":null,"abstract":"Background As both the prevalence and survival rates of cancer in children and adolescents has risen, longer-term effects of cancer treatment must be investigated. High-risk gonadotoxic chemotherapeutic agents such as cyclophosphamide may affect the ovarian reserve and impact female adolescent fertility. Anti-Mullerian hormone is a reliable marker to assess ovarian reserve. Objective To assess for a possible correlation between the cumulative dose of cyclophosphamide and serum anti-Mullerian hormone (AMH) levels among adolescent cancer patients. Methods This cross-sectional study included 12-18-year-old adolescent female cancer patients who had experienced menarche and received cyclophosphamide therapy. We recorded the patients’ full history, including menstrual history, computed the cumulative dose of cyclophosphamide received, and measured serum AMH levels. The correlation test was performed to evaluate for a possible correlation between the cumulative dose of cyclophosphamide and ovarian reserve as represented by AMH levels. Results Out of 12 female adolescent cancer patients, three complained of disturbances in their menstrual cycles. Low levels of AMH (<1.5 ng/mL) were noted in five patients. Median cumulative cyclophosphamide dose was 1,000 mg/m2 (range 1,000 to 5,250 mg/m2). Cumulative cyclophosphamide dose was negatively correlated with serum AMH levels, but this correlation was not statistically significant (r=-0.316, P=0.318). Conclusion This study has not been able to show a correlation between cumulative cyclophosphamide dose and serum AMH level. Regular evaluation of fertility and involvement of fertility team is recommended in adolescents receiving high-risk gonadotoxic chemotherapeutic agents.","PeriodicalId":19660,"journal":{"name":"Paediatrica Indonesiana","volume":"1 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2023-11-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139289715","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Maternal barriers to stimulating early childhood development on Tidore Island 蒂多尔岛上母亲在促进幼儿发展方面遇到的障碍

IF 0.2

Paediatrica Indonesiana Pub Date : 2023-11-02 DOI: 10.14238/pi63.5.2023.361-9

Gilbert Renardi Kusila

{"title":"Maternal barriers to stimulating early childhood development on Tidore Island","authors":"Gilbert Renardi Kusila","doi":"10.14238/pi63.5.2023.361-9","DOIUrl":"https://doi.org/10.14238/pi63.5.2023.361-9","url":null,"abstract":"Background The first 5 years of life provide a foundation for neuroplastic development, which establishes the capacity to accomplish complicated tasks in later life. However, this period is vulnerable to multiple stressors and adversities that prevent children from achieving age-related developmental milestones. Mothers as primary caregivers may find it challenging to engage her child in stimulating activities. Objectives To understand maternal barriers to stimulating early childhood development and potential interventions that can be developed. Methods This explorative, qualitative study was conducted in 13 different service coverage areas of the Soasio Community Health Center (Puskesmas), Tidore Islands, North Maluku, Indonesia. A total of 30 mothers participated in structured interview sessions. The analysis was conducted inductively, by generating some key issues from the interview. Results Eight maternal barriers to engaging in child stimulation activities were found: (1) family members, (2) gender-related interaction, (3) partial understanding of child health-related information, (4) prioritizing one developmental achievement over others, (5) timidity in decision making, (6) delaying stimulation due to overreliance on the role of school, (7) responsive feeding, and (8) media. Maternal motivation, societal awareness of child development, and support of maternal and family mental health are needed to improve maternal engagement in child stimulation. Conclusions Family, community, and life experiences may become maternal barriers to stimulating childhood development. Providing better social support, information access, and woman empowerment in decision-making will help mothers to be more engaged in child development stimulation activities.","PeriodicalId":19660,"journal":{"name":"Paediatrica Indonesiana","volume":"54 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2023-11-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139290936","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Prophylactic efficacy of 400 vs. 200 mg/kg /day calcium gluconate to prevent neonatal hypocalcemia 400 与 200 毫克/千克/天葡萄糖酸钙预防新生儿低钙血症的疗效对比

IF 0.2

Paediatrica Indonesiana Pub Date : 2023-11-01 DOI: 10.14238/pi63.5.2023.346-52

Liza Apsera, P. Sianturi, S. Nafianti

{"title":"Prophylactic efficacy of 400 vs. 200 mg/kg /day calcium gluconate to prevent neonatal hypocalcemia","authors":"Liza Apsera, P. Sianturi, S. Nafianti","doi":"10.14238/pi63.5.2023.346-52","DOIUrl":"https://doi.org/10.14238/pi63.5.2023.346-52","url":null,"abstract":"Background Serum calcium is at its lowest level within 24–48 hours after birth, rendering the neonate vulnerable to hypocalcemia. In our center, despite prophylactic administration of 200 mg/kg/day calcium gluconate, the prevalence of neonatal hypocalcemia remains high. Aim To determine the prophylactic efficacy of 400 vs. 200 mg/kg/day calcium gluconate in preventing neonatal hypocalcemia. Methods A randomized clinical trial with a pre- and post-test experimental design was done on neonates who fasted or received only minimal enteral feeding. Subjects were randomized to receive either 400 mg/kg/day (intervention group) or 200 mg/kg/day (control group) of intravenous calcium gluconate. We compared serum ionized calcium levels on the first day of admission before calcium gluconate administration and on the third day of hospitalization between the intervention and control groups. Results The median ionized calcium levels in the intervention vs. control group before calcium gluconate administration was 1.16 (range 0.4-2.4) mmol/L vs. 1.15 (range 0.6-4.5) mmol/L , respectively (P=0.561). After three days of calcium gluconate administration, the median ionized calcium level was 1.19 (range 0.7-1.45) mmol/L vs. 1.19 (range 0.68-4.6) mmol/L in the intervention vs. control group, respectively (P=0.828). The difference in pre- vs. post-administration ionized calcium levels was significant within the intervention group (P=0.032), but not within the control group (P=0.128). Conclusion Prophylactic intravenous calcium gluconate at 400 mg/kg/day was not more effective in preventing neonatal hypocalcemia than 200 mg/kg/day.","PeriodicalId":19660,"journal":{"name":"Paediatrica Indonesiana","volume":"818 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139299473","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Intestinal microbiota and health in infants and children 婴幼儿肠道微生物群与健康

IF 0.2

Paediatrica Indonesiana Pub Date : 2023-10-31 DOI: 10.14238/pi63.5.2023.325-7

Fabian Hendricx, Yvan Vandenplas

引用次数: 0

Development, validity, and reliability of a questionnaire on mothers’ knowledge in complementary feeding practices (PI-MPASI) in Indonesia 印度尼西亚母亲辅食喂养知识问卷（PI-MPASI）的开发、有效性和可靠性

IF 0.2

Paediatrica Indonesiana Pub Date : 2023-10-30 DOI: 10.14238/pi63.5.2023.335-45

Rini Andriani, B. Supriyatno, A. Kekalih, D. Sjarif

{"title":"Development, validity, and reliability of a questionnaire on mothers’ knowledge in complementary feeding practices (PI-MPASI) in Indonesia","authors":"Rini Andriani, B. Supriyatno, A. Kekalih, D. Sjarif","doi":"10.14238/pi63.5.2023.335-45","DOIUrl":"https://doi.org/10.14238/pi63.5.2023.335-45","url":null,"abstract":"Background A number of complementary educational feeding modules have been circulating in the community, but mothers have yet to use them optimally. There is an urgent need for an effective educational method on appropriate complementary feeding and an instrument to measure maternal knowledge in proper complementary feeding practices. Objective To develop and assess the validity and reliability of a questionnaire on complementary feeding practices. Methods We conducted a qualitative study to develop a questionnaire followed by a cross-sectional study to test the validity and the reliability of the PI-MPASI questionnaire. The research team designed the PI-MPASI questionnaire through a literature review with a team of experts, based on the evidence-based feeding practice recommendations for infants and toddlers in Indonesia as compiled by the Indonesian Pediatric Society (IPS) in 2015. Content validation was carried out through expert review, whilst the construct validity and the reliability were tested on 110 mothers who met the inclusion criteria. Results In the content validity assessment, an average congruent percentage of 90% was obtained for the sub-themes of time, nutritional adequacy, safety, and feeding responsiveness as the four essential points that mothers should know regarding proper complementary feeding practices. Most of the item scores showed moderate to high correlations with the total score, with reliability test showcasing a good internal consistency (Cronbach's alpha = 0.715). Conclusion This study showed that our questionnaire on mothers’ knowledge in complementary feeding practices (PI-MPASI) is a valid and reliable instrument to assess maternal knowledge on correct complementary feeding practices in Indonesia.","PeriodicalId":19660,"journal":{"name":"Paediatrica Indonesiana","volume":"16 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2023-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139309728","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0