Osaka city medical journal最新文献_第9页

Huge liver abscess radiologically mimicking cystadenocarcinoma. 巨大肝脓肿，影像学表现酷似囊腺癌。

Osaka city medical journal Pub Date : 2009-06-01

Takatsugu Yamamoto, Nobusuke Fukumoto, Tsuyoshi Ichikawa, Seikan Hai, Masao Ogawa, Shogo Tanaka, Takahiro Uenishi, Tadashi Tsukamoto, Kazuhiro Hirohashi, Shoji Kubo, Koichi Ohno

{"title":"Huge liver abscess radiologically mimicking cystadenocarcinoma.","authors":"Takatsugu Yamamoto, Nobusuke Fukumoto, Tsuyoshi Ichikawa, Seikan Hai, Masao Ogawa, Shogo Tanaka, Takahiro Uenishi, Tadashi Tsukamoto, Kazuhiro Hirohashi, Shoji Kubo, Koichi Ohno","doi":"","DOIUrl":"","url":null,"abstract":"A 72-old-year Japanese man was incidentally found to have out liver dysfunction on serum examination and a cystic tumor in the liver. Dynamic computed tomography revealed a solitary cystic tumor 14 cm in diameter with multiple septa. The cyst wall was occasionally irregular with hyperarterial inflow. After admission, he suffered from fever and right upper abdominal pain. We suspected cystadenocarcinoma with intraluminal infection. Percutaneous transhepatic drainage was performed. However, neither cytologic examination nor culture test was positive. The cystic tumor had been decreasing in size, and hepatic resection performed. Macroscopically, the tumor was a gray-yellow solid tumor with a fine boundary between tumor and liver parenchyma, and the cystic lesion collapsed. Microscopically, the tumor consisted of hepatic infarction, degenerated Glisson's sheath, and chronic inflammation, and chronic liver abscess was diagnosed. Most cases of bacterial liver abscess can be diagnosed because progression is accompanied by typical signs. However, it is difficult to diagnose liver abscess in the chronic phase because chronic liver abscesses exhibit various features on imaging series without typical signs or symptoms. When atypical liver cyst is found, the possibility of liver abscess in chronic phase should be considered.","PeriodicalId":19613,"journal":{"name":"Osaka city medical journal","volume":"55 1","pages":"53-9"},"PeriodicalIF":0.0,"publicationDate":"2009-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"28376550","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Acceleration time of fetal arterial blood flow velocity waveforms: a preliminary study. 胎儿动脉血流速度波形加速时间的初步研究。

Osaka city medical journal Pub Date : 2009-06-01

Sachiyo Nishimoto, Yuichiro Nakai, Tomoyo Yasui, Mie Tahara, Akemi Nakano, Makiko Matsumoto, Hiroyuki Nobeyama, Rika Nishihara, Naoko Iwanaga, Osamu Ishiko

{"title":"Acceleration time of fetal arterial blood flow velocity waveforms: a preliminary study.","authors":"Sachiyo Nishimoto, Yuichiro Nakai, Tomoyo Yasui, Mie Tahara, Akemi Nakano, Makiko Matsumoto, Hiroyuki Nobeyama, Rika Nishihara, Naoko Iwanaga, Osamu Ishiko","doi":"","DOIUrl":"","url":null,"abstract":"Background: Doppler ultrasonography has been widely used for fetal estimation, but most of them were estimated by the resistance and pulsatility indices. Acceleration time is one of parameters of flow velocity waveforms, but only few reports had discussed acceleration time of fetal circulation.Methods: We analyzed Doppler flow velocity waveforms of fetal middle cerebral artery, descending aorta and abdominal umbilical artery obtained from 70 normal pregnant women between 18 and 40 weeks. Acceleration time was cross-sectionaly examined throughout pregnancy course.Results: The acceleration times revealed no remarkable changes throughout pregnancy course in the middle cerebral artery, but significant increases were observed in the acceleration time of the descending aorta between 18-23 and 24-32 weeks. It also significantly decreased after 33 weeks compared to that of 18-32 weeks in the umbilical artery.Conclusions: The acceleration time in fetal descending aorta is significantly shorter than that in the abdominal umbilical artery between 18 and 32 weeks of gestation. The umbilical arterial acceleration time apparently decreases throughout pregnancy course. Its values are almost double for that in the descending aorta between 18 and 23 weeks, but it becomes to be equal to the aortic acceleration time. The continuous decrease of the umbilical arterial acceleration time might be a result of a relative increase of placental flow.","PeriodicalId":19613,"journal":{"name":"Osaka city medical journal","volume":"55 1","pages":"29-34"},"PeriodicalIF":0.0,"publicationDate":"2009-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"28376545","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Survival analysis of malignant melanoma in Japan--multivariate analysis of prognostic factors. 日本恶性黑色素瘤的生存分析——预后因素的多变量分析

Osaka city medical journal Pub Date : 2009-06-01

Shinji Uehara, Riei Kamo, Teruichi Harada, Masamitsu Ishii

{"title":"Survival analysis of malignant melanoma in Japan--multivariate analysis of prognostic factors.","authors":"Shinji Uehara, Riei Kamo, Teruichi Harada, Masamitsu Ishii","doi":"","DOIUrl":"","url":null,"abstract":"Background: The prognostic factors of cutaneous melanoma reported in Japan were different from those in US and Europe in evaluating the prognostic values of the biopsy types, sex, anatomic location and so on. The aim of this study was to identify the prognostic factors for survival in cutaneous melanoma in Japan by performing univariate and multivariate analyses.Methods: We studied a total of 103 patients with cutaneous melanoma, treated in Osaka City University Hospital during the period 1991-2003. Eleven factors were evaluated by uni- and multivariate analyses. Kaplan-Meier analyses were performed to estimate and compare five-year survival rates. After checking for independence, prognostic factors were then evaluated applying a Cox proportional hazards model in localized melanoma patients and in all invasive melanoma patients.Results: On univariate analysis, anatomic location, ulceration, tumor thickness, Clark's level, lymph node metastasis, distant metastasis and TNM staging were significantly related to five-year survival rates. Clark's level and TNM staging were excluded after checking for independence. Multivariate analysis revealed that significant prognostic factors were tumor thickness and anatomic location in localized melanoma patients, and distant metastasis, tumor thickness, sex and anatomic location in all invasive melanoma patients.Conclusions: Thinner tumors, female gender and location on the extremity are favorable prognostic features in malignant melanoma. Tumor thickness whose best cut-off point is 4 or 5 mm is the most important prognostic factor in predicting survival in the melanoma patient. These results were similar to those in U.S. and Europe.","PeriodicalId":19613,"journal":{"name":"Osaka city medical journal","volume":"55 1","pages":"35-52"},"PeriodicalIF":0.0,"publicationDate":"2009-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"28376546","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Utility of novel volumetric intravascular ultrasound analysis software for coronary artery disease. 新型冠状动脉疾病血管内超声分析软件的应用。

Osaka city medical journal Pub Date : 2009-06-01

Takara Tsumori, Toru Kataoka, Yoshiki Kobayashi, Gao Xiaohui, Hiroaki Takeshita, Nobuyuki Shirai, Ryo Matsumoto, Shinji Nakata, Shoichi Ehara, Minoru Yoshiyama

{"title":"Utility of novel volumetric intravascular ultrasound analysis software for coronary artery disease.","authors":"Takara Tsumori, Toru Kataoka, Yoshiki Kobayashi, Gao Xiaohui, Hiroaki Takeshita, Nobuyuki Shirai, Ryo Matsumoto, Shinji Nakata, Shoichi Ehara, Minoru Yoshiyama","doi":"","DOIUrl":"","url":null,"abstract":"Background: Volumetric intravascular ultrasound (IVUS) analysis has contributed significantly to the assessment of coronary artery disease. The aim of this study is to validate the novel IVUS analysis software (NICORAS) compared to the previously validated software (EchoPlaque).Methods: Selected from clinical cases, we used 30 IVUS images that utilized motorized pullback at 0.5 mm/sec. Judging from at least two vascular landmarks, identical coronary artery segments were selected and analyzed with two software systems (NICORAS and EchoPlaque). Lumen and external elastic membrane (EEM) borderlines were traced at every 0.5 mm interval. Plaque area was calculated as EEM minus lumen area. Then, volumetric IVUS data were calculated using interpolated frame data from which lumen, EEM, and plaque volume were computed.Results: The average analyzed coronary segment was 15.4 +/- 4.3 mm. There was excellent agreement between NICORAS and EchoPlaque for lumen volume (r = 0.999, p < 0.0001), EEM volume (r= 0.999, p < 0.0001), and plaque volume (r = 0.998, p < 0.0001).Conclusion: The new volumetric IVUS analysis software provided IVUS data similar to previously examined software.","PeriodicalId":19613,"journal":{"name":"Osaka city medical journal","volume":"55 1","pages":"1-7"},"PeriodicalIF":0.0,"publicationDate":"2009-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"28454364","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comparison of fundus autofluorescence of age-related macular degeneration between a fundus camera and a confocal scanning laser ophthalmoscope. 眼底相机与激光共聚焦扫描检眼镜对老年性黄斑变性眼底自身荧光的比较。

Osaka city medical journal Pub Date : 2009-06-01

Manabu Yamamoto, Takeya Kohno, Kunihiko Shiraki

{"title":"Comparison of fundus autofluorescence of age-related macular degeneration between a fundus camera and a confocal scanning laser ophthalmoscope.","authors":"Manabu Yamamoto, Takeya Kohno, Kunihiko Shiraki","doi":"","DOIUrl":"","url":null,"abstract":"Background: Fundus autofluorescence (FAF) has been examined using two devices, which were the conventional confocal scanning laser ophthalmoscope and the improved fundus camera. We examined the comparison of fundus autofluorescence (FAF) from a fundus camera (FC) and a confocal scanning laser ophthalmoscope (cSLO) in patients with age-related macular degeneration (AMD).Methods: Two hundreds ninety-two eyes of 202 AMD patients were examined for FAF. FAF images were captured with a FC and a cSLO system, and were compared for serous retinal detachment lesion (SRD), subretinal fibrovascular tissue lesion (FVM), pigment epithelial detachment lesion (PED), geographic atrophy lesion (GA), macular aria, and choroidal vessels.Results: Clear FAF images were obtained using both instruments in 212 eyes of 147 patients (72.6%). Correlations of FAF findings between the 2 systems existed for SRD, FVM, and GA, but not for PED. The FAF accordance rates between the 2 systems were 61.1% at SRD, 68.4% at FVM, 35% at PED, and 83.4% at GA; and GA had a significantly higher accordance ratio than other lesions. FAF images with the cSLO tended to hypoautofluorescence compared to those with a FC, except at GA. Maculas without any abnormal lesion of 41 eyes apparently hypoautofluorescence more with the cSLO than the FC. Some choroidal vessels autofluoresced in 21 eyes only with the FC.Conclusions: FAF examination differed between the two systems. To compare two FAF images may be useful for identifying pathogonomonic fundus changes undetectable by only either FAF examination.","PeriodicalId":19613,"journal":{"name":"Osaka city medical journal","volume":"55 1","pages":"19-27"},"PeriodicalIF":0.0,"publicationDate":"2009-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"28376543","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Evaluation of attention-deficit/hyperactivity disorder symptoms in male children with high-functioning pervasive developmental disorders. 高功能广泛性发育障碍男性儿童注意缺陷/多动障碍症状的评价

Osaka city medical journal Pub Date : 2008-06-01

Noriaki Matsushima, Dai Miyawaki, Hisashi Tsuji, Kazuhiro Takahashi, Akemi Horino, Takeshi Kawaguchi, Futoshi Suzuki, Nobuo Kiriike

{"title":"Evaluation of attention-deficit/hyperactivity disorder symptoms in male children with high-functioning pervasive developmental disorders.","authors":"Noriaki Matsushima, Dai Miyawaki, Hisashi Tsuji, Kazuhiro Takahashi, Akemi Horino, Takeshi Kawaguchi, Futoshi Suzuki, Nobuo Kiriike","doi":"","DOIUrl":"","url":null,"abstract":"Background: Although there are many reports of high rates of hyperactivity and attention deficits in children with Pervasive Developmental Disorders (PDD), controversy remains about the applicability of the diagnosis of Attention-Deficit/Hyperactivity Disorder (ADHD) to PDD children. The present study elucidates the similarities and differences of ADHD symptoms in PDD children compared to ADHD children.Methods: Twenty-seven male children with PDD+ADHD Combined type (ADHD-C), 17 males with ADHD-C, and 9 males with PDD without ADHD-C, were compared on measures of ADHD symptoms and related behaviors using parent ratings and teacher ratings on the ADHD Rating Scale (ADHDRS), the Child Behavior Checklist (CBCL) and the Teacher Report Form (TRF).Results: The PDD+ADHD-C and the ADHD-C groups had significantly higher ratings than the PDD only group for all the scores on both the parent-rated and the teacher-rated ADHDRS. The ADHD-C and PDD+ADHD-C groups had significantly higher scores than the PDD group on Delinquent Behavior, Aggressive Behavior, and Externalizing Behavior of the CBCL and on Delinquent Behavior of the TRF; there were no significant differences between the ADHD-C and PDD+ADHD-C groups on any scores of the CBCL and TRF.Conclusions: The PDD+ADHD-C and ADHD-C groups share a similar profile of ADHD symptoms and externalizing behaviors, and the comorbidity of ADHD and PDD should be suspected when ADHD symptoms are present in PDD children.","PeriodicalId":19613,"journal":{"name":"Osaka city medical journal","volume":"54 1","pages":"1-10"},"PeriodicalIF":0.0,"publicationDate":"2008-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"27698611","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The effects of nifekalant hydrochloride on the QT dispersion after direct-current defibrillation. 盐酸尼非卡兰特对直流除颤后QT离散度的影响。

Osaka city medical journal Pub Date : 2008-06-01

Keiko Maeda, Masahiko Takagi, Hiroaki Tatsumi, Eiichiro Nakagawa, Minoru Yoshiyama

{"title":"The effects of nifekalant hydrochloride on the QT dispersion after direct-current defibrillation.","authors":"Keiko Maeda, Masahiko Takagi, Hiroaki Tatsumi, Eiichiro Nakagawa, Minoru Yoshiyama","doi":"","DOIUrl":"","url":null,"abstract":"Background: Although nifekalant hydrochloride (NIFE) has been demonstrated to suppress ventricular tachyarrhythmia, especially electrical storm, the mechanism by which it does so is still unclear. We examined its effects on the spatial dispersion of repolarization (SDR) after implantable cardioverter-defibrillator (ICD) shock.Methods and results: In twenty five patients with an ICD, we recorded the 87-lead ECG during sinus rhythm (the CONTROL group) under general anesthesia, after NIFE administration alone, and just after termination of induced ventricular fibrillation (VF) by ICD shock with or without NIFE administration. In all recordings, the corrected QT interval (QTc) was measured in each lead. The dispersion of QTc (QTc-D; maximum QTc minus minimum QTc) was also measured. Compared with the CONTROL, the QTc-D exhibited significant deterioration after ICD shock (61 +/- 12, 91 +/- 24 ms(1/2), respectively, p < 0.001). However, the QTc-D after NIFE administration either with or without ICD shock did not differ from the CONTROL group (65 +/- 20, 61 +/- 18, and 61 +/- 12 ms(1/2), respectively, p = 0.99).Conclusions: NIFE suppressed the deterioration of SDR by ICD shock. This might be a mechanism by which NIFE suppresses recurrence of ventricular tachyarrhythmia after ICD shock.","PeriodicalId":19613,"journal":{"name":"Osaka city medical journal","volume":"54 1","pages":"11-9"},"PeriodicalIF":0.0,"publicationDate":"2008-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"27698612","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Contralateral pneumothorax after lung cancer surgery: report of two cases. 肺癌术后对侧气胸2例报告。

Osaka city medical journal Pub Date : 2008-06-01

Takashi Iwata, Kiyotoshi Inoue, Noritoshi Nishiyama, Nobuhiro Izumi, Shinjiro Mizuguchi, Ryuhei Morita, Takuma Tsukioka, Shigefumi Suehiro

{"title":"Contralateral pneumothorax after lung cancer surgery: report of two cases.","authors":"Takashi Iwata, Kiyotoshi Inoue, Noritoshi Nishiyama, Nobuhiro Izumi, Shinjiro Mizuguchi, Ryuhei Morita, Takuma Tsukioka, Shigefumi Suehiro","doi":"","DOIUrl":"","url":null,"abstract":"Due to recent increases in numbers of patients who underwent surgical treatments for lung cancer, numbers of complications of contralateral pneumothorax after lung surgery are suggested to increase. Moreover, recent spread of surgical indication to elderly people and patients with severely damaged pulmonary function may lead postoperative complication of contralateral pneumothorax more lethal. We herein describe 2 cases of contralateral pneumothorax following lung cancer surgery with a review of recent literatures. Case 1 underwent left lower lobectomy with combined partial resection of the chest wall for lung cancer. Five months later, he suffered from contralateral pneumothorax and respiratory failure. Immediate chest drainage followed by bullectomy and pleurodesis were performed. Case 2 was surgically treated for left lung cancer. Preoperative computed tomography incidentally demonstrated contralateral pneumothorax. Chest drainage was started immediately, followed by left lower lobectomy. Contralateral bullectomy and pleurodesis were performed 6 days after lobectomy. Both patients have been well without recurrence of pneumothorax or lung cancer.","PeriodicalId":19613,"journal":{"name":"Osaka city medical journal","volume":"54 1","pages":"41-6"},"PeriodicalIF":0.0,"publicationDate":"2008-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"27698615","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Long-term cardiovascular outcomes following ischemic heart disease in patients with and without peripheral vascular disease. 伴有或不伴有周围血管疾病的缺血性心脏病患者的长期心血管预后

Osaka city medical journal Pub Date : 2008-06-01

Shinji Nakata, Yoshiaki Yokoi, Ryo Matsumoto, Nobuyuki Shirai, Ryo Otsuka, Kenichi Sugioka, Hidetoshi Yoshitani, Shoichi Ehara, Toru Kataoka, Minoru Yoshiyama

{"title":"Long-term cardiovascular outcomes following ischemic heart disease in patients with and without peripheral vascular disease.","authors":"Shinji Nakata, Yoshiaki Yokoi, Ryo Matsumoto, Nobuyuki Shirai, Ryo Otsuka, Kenichi Sugioka, Hidetoshi Yoshitani, Shoichi Ehara, Toru Kataoka, Minoru Yoshiyama","doi":"","DOIUrl":"","url":null,"abstract":"Background: Peripheral vascular disease (PVD) is associated with an increased risk of cardiovascular disease. However, few studies have evaluated the prognosis of asymptomatic PVD in patients with coronary artery disease (CAD).Methods: The aim of the study was to determine the prevalence of asymptomatic and symptomatic PVD in patients with ST-elevated myocardial infarction (STEMI) or unstable angina pectoris (UAP) who underwent percutaneous coronary intervention (PCI), and to conduct a 3-year follow-up for cardiovascular events. Systemic atherosclerosis was evaluated, using duplex ultrasonography in 380 consecutive patients who had undergone PCI from January 2003 to December 2005.Results: Twenty-four percent of the CAD patients had PVD. Patients with PVD had significantly more risk factors for atherosclerosis, including increased age, diabetes mellitus, smoking (p < 0.05), and multivessel CAD (p < 0.001). Multivariate regression analysis demonstrated that STEMI, PVD and multivessel CAD were independent predictors for major adverse cardiac events (MACE) (p < 0.05). Kaplan-Meier curves for MACE in all the patients showed that the MACE rates were significantly higher in STEMI and PVD cases compared with other cases (p < 0.05). We also classified patients with PVD into symptomatic (53%) and asymptomatic (47%) cases, and the MACE rates between these groups did not differ significantly (p < 0.82).Conclusions: There is a high prevalence of asymptomatic PVD in patients with CAD and even asymptomatic PVD is associated with increased CAD mortality.","PeriodicalId":19613,"journal":{"name":"Osaka city medical journal","volume":"54 1","pages":"21-30"},"PeriodicalIF":0.0,"publicationDate":"2008-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"27698613","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Impact of body mass index and Framingham risk score on coronary artery plaque. 体重指数和Framingham风险评分对冠状动脉斑块的影响。

Osaka city medical journal Pub Date : 2008-06-01

Hiroaki Takeshita, Yoshihisa Shimada, Yoshiki Kobayashi, Hiroki Nishioka, Shoichi Ehara, Toru Kataoka, Minoru Yoshiyama

{"title":"Impact of body mass index and Framingham risk score on coronary artery plaque.","authors":"Hiroaki Takeshita, Yoshihisa Shimada, Yoshiki Kobayashi, Hiroki Nishioka, Shoichi Ehara, Toru Kataoka, Minoru Yoshiyama","doi":"","DOIUrl":"","url":null,"abstract":"Background: It is still unclear whether traditional risk factors for heart disease and body weight correlate with the progression of left main coronary artery (LMCA) atherosclerosis. Thus, the aim of this study was to evaluate the cross-sectional relation between conventional risk score or metabolic disorder and non-stenotic LMCA atherosclerosis using intravascular ultrasound (IVUS).Methods: We analyzed procedural and demographic data from 217 consecutive patients undergoing intervention for a left anterior descending or left circumflex coronary artery lesion, including their cardiovascular risk (Framingham risk score) and degree of adiposity. IVUS measurements for subclinical LMCA plaque were obtained in all patients and compared to their risk score (low, intermediate or high risk [< or =10%, 10-20%, and > or =20%, respectively]), with volumetric IVUS analyses being performed for the entire LMCA. Patients were further stratified by body weight (normal vs overweight/obesity [body mass index > or =25 kg/m2]).Results: Plaque volume index was greater in patients with high and intermediate risk groups compared to the low risk group (plaque volume index; 9.8 +/- 2.9 mm3/mm and 10.1 +/- 3.0 mm3/mm vs. 8.3 +/- 2.7 mm3/mm, p=0.017 and p=0.0002, respectively). Plaque volume index was also greater in patients in the overweight/obesity group compared to the normal weight group (plaque volume index; 10.2 +/- 2.9 mm3/mm vs 9.1 +/- 3.0 mm3/mm, p=0.005). Linear regression analysis identified overweight/obesity (p=0.034) and high 10-year CAD risk (p=0.003) as independent predictors of increased LMCA plaque volume index.Conclusions: Conventional coronary risk factors, as well as adiposity itself, related to the volume of coronary plaque at non-stenotic LMCA.","PeriodicalId":19613,"journal":{"name":"Osaka city medical journal","volume":"54 1","pages":"31-9"},"PeriodicalIF":0.0,"publicationDate":"2008-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"27698614","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0