{"title":"Research Review on the Mechanisms of Pathological New Bone Formation in Ankylosing Spondylitis.","authors":"Xingshun Zhou, Wenhui Ma, Hengsheng Zhang, Zilin Zhao, Cong Huang","doi":"10.2147/ORR.S540714","DOIUrl":"10.2147/ORR.S540714","url":null,"abstract":"<p><p>Ankylosing spondylitis (AS) is a long-lasting autoimmune disorder marked by inflammatory processes affecting the spinal column and sacroiliac joints, alongside abnormal bone growth. This review aims to summarize the mechanisms underlying pathological new bone formation in AS, focusing on key cell types, molecular pathways, and their roles in disease progression. We will discuss the interplay between osteoblasts and osteoclasts, the cytokines and signaling pathways that influence new bone formation, and how recent research findings contribute to our understanding of this complex process. Through a comprehensive analysis of relevant literature, this review seeks to provide a theoretical foundation and direction for future therapeutic strategies.</p>","PeriodicalId":19608,"journal":{"name":"Orthopedic Research and Reviews","volume":"17 ","pages":"469-479"},"PeriodicalIF":2.3,"publicationDate":"2025-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12439829/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145081287","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Two Vertebral Arteries Running Above the Articular Pillars of the Cervical Vertebrae: A Case Report.","authors":"Shilei Li, Hongqi Zhang, Guanteng Yang, Mingxing Tang, Qile Gao","doi":"10.2147/ORR.S534910","DOIUrl":"10.2147/ORR.S534910","url":null,"abstract":"<p><strong>Purpose: </strong>This report discusses a rare case of a vertebral artery that runs above the articular pillars of the cervical vertebrae.</p><p><strong>Methods: </strong>A 19-year-old male patient presented after a fall due to paroxysmal dizziness and gait abnormalities, and underwent cervical computed tomography angiography (CTA) for preoperative assessment before posterior cervical surgery.</p><p><strong>Results: </strong>Through cervical CTA imaging, we unexpectedly discovered two variant vertebral arteries positioned superficial to the articular pillars of the cervical vertebrae.</p><p><strong>Conclusion: </strong>This rare case emphasizes the importance of vascular evaluation prior to cervical surgery. CTA imaging is necessary before patients requiring posterior cervical surgery. This unusual vertebral artery may have contributed to the patient's symptoms.</p>","PeriodicalId":19608,"journal":{"name":"Orthopedic Research and Reviews","volume":"17 ","pages":"465-468"},"PeriodicalIF":2.3,"publicationDate":"2025-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12433623/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145070163","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Challenges for the Female Surgeon in Orthopedic Surgery - A Scoping Review.","authors":"Yasmen Alrumaidhi, Norah Alenizi, Nawar Almulla, Zainab Almousa, Danah Alenezi, Ali Lari","doi":"10.2147/ORR.S524482","DOIUrl":"10.2147/ORR.S524482","url":null,"abstract":"<p><strong>Background: </strong>The number of female doctors graduating from medical schools worldwide is increasing; however, orthopedic surgery remains one of the least gender-diverse surgical fields.</p><p><strong>Objective: </strong>This scoping review aims to map the literature on the challenges faced by female orthopedic surgeons, categorize them into key domains, and identify essential gaps to guide future research and institutional reform.</p><p><strong>Methods: </strong>A scoping review study design was employed, utilizing the Arksey and O'Malley framework. PubMed, Scopus, and Web of Science were searched for articles published between January 2000 and 2024. Papers that addressed challenges faced by female orthopedic residents and surgeons were included; of the studies screened, 92 met the inclusion criteria.</p><p><strong>Results: </strong>Challenges were discussed in three main domains: female representation, the health and occupational risks, and the emotional environment. Approximately 23 challenges were identified. While the increase in female representation in orthopedic surgery more than doubled between 2000 and 2020, gender disparity persists. Musculoskeletal injuries were identified as the most common occupational health concern. Microaggressions were described in several forms: verbal comments, assumptions about skills, traditional role stereotypes, sexist language, and exclusion from informal networks.</p><p><strong>Limitations: </strong>The study's limitations include unexplored multiple challenges due to the limited availability of data, such as unequal pay, patient preferences, and military orthopedic care. Most of the included studies were cross-sectional surveys, which limits generalizability and causal inference.</p><p><strong>Conclusion: </strong>This review highlights the persistent gender-related challenges in the field of orthopedic surgery. Initiatives for mentorship and representation are in place and appear promising. Nonetheless, challenges related to occupational safety, well-being support, and leadership roles remain inadequately addressed. Future efforts must prioritize mentorship, ergonomic equipment design, strategies to address microaggressions, and institutional commitment to support female orthopedic surgeons.</p>","PeriodicalId":19608,"journal":{"name":"Orthopedic Research and Reviews","volume":"17 ","pages":"451-464"},"PeriodicalIF":2.3,"publicationDate":"2025-09-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12422126/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145040979","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Maharshi S Nagda, Lyndsay E Somerville, Michael Shehata, Brent A Lanting
{"title":"Bikini versus Traditional Incision in DAA THA: Patient Satisfaction, Surgeon Observation, and LFCN Damage.","authors":"Maharshi S Nagda, Lyndsay E Somerville, Michael Shehata, Brent A Lanting","doi":"10.2147/ORR.S524339","DOIUrl":"10.2147/ORR.S524339","url":null,"abstract":"<p><strong>Background: </strong>The bikini incision (BI) used in direct anterior approach total hip arthroplasty (DAA THA) theoretically improves scar aesthetics by utilizing the inguinal crease; however, current literature suggests its transverse orientation increases the risk of injury to the lateral femoral cutaneous nerve (LFCN). This study examines (1) patient and surgeon satisfaction with scar appearance and (2) differences in post-operative LFCN sensation between the vertical, traditional incision (TI) and the BI.</p><p><strong>Questions/purposes: </strong>In this pilot study, the following questions were investigated: (1) Do BI patients experience increased scar satisfaction compared to TI patients? (2) Does the surgeon report greater satisfaction with BI scars compared to TI scars? (3) Do BI patients have a reduced incidence of LFCN sensory disturbance compared to TI patients?.</p><p><strong>Patients and methods: </strong>Fifty-five patients (32 TI and 23 BI), at least 6 months post-DAA THA, were recruited from a high-volume, fellowship-trained reconstruction surgeon. 91% of the BI group was female, compared to 50% of the TI group. The Patient and Observer Scar Assessment Scale (POSAS) allowed patients to describe scar appearance and complications (eg, pain and itchiness) and enabled the surgeon to assess vascularity, pigmentation, thickness, relief, pliability, and surface area. Monofilament testing at superomedial, superolateral, inferomedial, and inferolateral quadrants of the anterior thigh assessed LFCN hypoesthesia.</p><p><strong>Results: </strong>POSAS analysis demonstrated that (1) BI patients were significantly more satisfied with scar appearance than TI patients (p < 0.05), and (2) the surgeon was significantly more satisfied with BI scars than TI scars (p < 0.05). (3) Monofilament testing showed significantly more LFCN impairment in the inferomedial quadrant of the TI group (p < 0.0125).</p><p><strong>Conclusion: </strong>This study demonstrates improved patient and surgeon satisfaction with the BI. Contrary to current beliefs, the BI better preserves LFCN innervation relative to the TI.</p>","PeriodicalId":19608,"journal":{"name":"Orthopedic Research and Reviews","volume":"17 ","pages":"437-450"},"PeriodicalIF":2.3,"publicationDate":"2025-09-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12422138/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145040940","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Erik Hohmann, Maketo Molepo, Maritz Laubscher, Kevin Tetsworth
{"title":"Open Tibial Fractures Part 1: A Narrative Review of Initial Treatment and Potential Applicability to the Southern African Context.","authors":"Erik Hohmann, Maketo Molepo, Maritz Laubscher, Kevin Tetsworth","doi":"10.2147/ORR.S534233","DOIUrl":"10.2147/ORR.S534233","url":null,"abstract":"<p><p>Treatment guidelines for open tibial fractures are well established in high-income countries, but their implementation in low-resource settings remains challenging. To date, only one African country has attempted to formulate national, consensus-based guidelines that cover key aspects such as antibiotic administration, initial stabilization, surgical debridement, wound management, and definitive fixation. This narrative review summarizes current principles for the initial management of open tibial shaft fractures and evaluates their relevance in the Southern African context, particularly in rural and resource-constrained environments. Given the limited availability of advanced imaging, specialized implants, and soft-tissue coverage expertise, clinicians must adapt existing protocols to local capacities. This review highlights areas where treatment recommendations from high-income settings may not be feasible and identifies practical considerations for applying initial management principles in Southern Africa. The need for context-specific, resource-appropriate guidelines is emphasized.</p>","PeriodicalId":19608,"journal":{"name":"Orthopedic Research and Reviews","volume":"17 ","pages":"427-436"},"PeriodicalIF":2.3,"publicationDate":"2025-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12414457/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145023856","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Samuel J Wu, Karen L Hernandez, David N Armond, Patrick C McCulloch
{"title":"Changing Utilization of Primary Anatomic and Reverse Shoulder Arthroplasty in a Single High-Volume Institution: A Retrospective Cohort Study.","authors":"Samuel J Wu, Karen L Hernandez, David N Armond, Patrick C McCulloch","doi":"10.2147/ORR.S515073","DOIUrl":"10.2147/ORR.S515073","url":null,"abstract":"<p><strong>Objective: </strong>The incidence of total shoulder arthroplasty (TSA) in the United States continues to climb as an aging yet active population increases demand for the procedure. Due to promising clinical results out of Europe, improvement in prosthesis design, and wider acceptance of reverse total shoulder arthroplasty (rTSA), this study was designed to evaluate how rTSA and anatomical TSA (aTSA) utilization, patient selection, and length of stay have changed at a single institution.</p><p><strong>Methods: </strong>This was a retrospective cohort study of patients from one hospital system between 2017 and 2023. Inclusion criteria included primary TSA cases using CPT codes. Exclusion criteria included hemiarthroplasty, revision arthroplasty, non-arthroplasty procedures. Primary arthroplasty procedures were separated into reverse or anatomic cohorts for analysis. Independent sample <i>t</i>-tests were used to compare continuous data between the first and last year of cohort data and to compare parameters between procedure types. Chi-square analysis was used for frequency-based data comparisons. Type-I error was set at α=0.05 for all analyses.</p><p><strong>Results: </strong>From all 2774 shoulder arthroplasty cases identified, 2604 TSA cases were included in the final statistical analyses, 2114 of which were rTSA and 490 anatomic TSA. Comparison of arthroplasties in 2017 and 2023 revealed, rTSA increased from 115 surgery cases to 549, or 77.18% to 82.81% over the study period (p < 0.001). Anatomic TSA increased in total surgery cases from 29 to 111, (p = 0.655) and thus signifies an overall decrease in anatomic surgery utilization from 19.46% to 16.74%. Data showed an increase in average patient age for rTSA and decreased procedure time and length of stay for both groups.</p><p><strong>Conclusion: </strong>rTSA utilization has surpassed and continues to increase relative to anatomic TSA. Peri-operative management of shoulder replacement has become more efficient with significantly decreased procedure time and decreased total hospital length of stay after primary TSA.</p>","PeriodicalId":19608,"journal":{"name":"Orthopedic Research and Reviews","volume":"17 ","pages":"421-426"},"PeriodicalIF":2.3,"publicationDate":"2025-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12415622/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145030242","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Effectiveness of Ultrasound Guided Intraarticular Injections with Lidocaine and Triamcinolone: A Retrospective Study of Primary Hip Injections.","authors":"Maya Jurgens, Tarandeep Sidhu, Amir A Jamali","doi":"10.2147/ORR.S525289","DOIUrl":"10.2147/ORR.S525289","url":null,"abstract":"<p><strong>Background: </strong>Ultrasound guided hip injections have played a major role in the in-office diagnosis and treatment of a variety of traumatic and degenerative hip joint conditions. There is limited information as to the onset and duration of relief from these types of injections using a uniform medication combination.</p><p><strong>Hypothesis/purpose: </strong>The purpose of the study is to evaluate the clinical characteristics of a population of patients undergoing ultrasound guided hip corticosteroid injections. We hypothesized that these injections have a low complication rate and a high degree of pain relief for patients.</p><p><strong>Study design: </strong>Case Series.</p><p><strong>Methods: </strong>We performed a retrospective study on 117 first time hip intraarticular injections performed by one operator using a single ultrasound machine and using the identical technique. In all cases, the hip joint was injected with 4 mL of 1% lidocaine and triamcinolone 40mg. The preinjection pain score was available in 98 hips with a mean of 6.4 ± 1.9 (mean ± S.D).</p><p><strong>Results: </strong>96% of patients had immediate improvement of pain (113/117). There were more right than left hips (67 vs 50) and more females than males (63 vs 54). The most common underlying diagnosis was osteoarthritis (53%). The relief duration was less than 3 months for most patients but longer than 6 months in 4 patients. Adverse outcomes were minimal with no infections and one allergic reaction.</p><p><strong>Conclusion: </strong>This series represents the largest series of first time hip intraarticular injections with lidocaine and triamcinolone. This regimen has a high probability of immediate pain relief and low complications based on this series of patients.</p>","PeriodicalId":19608,"journal":{"name":"Orthopedic Research and Reviews","volume":"17 ","pages":"413-420"},"PeriodicalIF":2.3,"publicationDate":"2025-08-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12383004/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144963686","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Systematic Review of Nerve Adhesion Barriers for Peripheral Nerve Regeneration and Functional Recovery.","authors":"Oryza Satria, Dina Aprilya","doi":"10.2147/ORR.S506375","DOIUrl":"10.2147/ORR.S506375","url":null,"abstract":"<p><strong>Background: </strong>Peripheral nerve injury (PNI) is characterized by poor functional outcomes, insufficient nerve regeneration, and deterioration of sensory and motor function. Factors such as nerve tissue loss and extended denervation of proximal nerves impede regeneration. Therapeutic interventions include microsurgical techniques and nerve-guide conduits. However, nerve adhesion, which restricts nerve mobility, also contributes to inadequate healing. Surgical modifications and chemical agents are used to mitigate adhesion.</p><p><strong>Methods: </strong>We searched across four databases, PubMed, Cochrane Database of Systematic Reviews, EMBASE, and Medline, using the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) 2020 guidelines. The study quality and risk of bias were assessed using the systematic review center for laboratory animal experimentation (SYRCLE)'s and Cochrane RoB-2 tools.</p><p><strong>Results: </strong>Out of 549 studies, 5 studies met our inclusion criteria, consisting of four animal studies and one randomized controlled trial involving human participants. Different nerve adhesion materials were evaluated in the studies included. Histological evaluation of nerve regeneration generally shows more advanced regenerative hallmarks in the intervention group. Additionally, in terms of motor and sensory function, improvements were seen in the majority of parameters observed in all studies included.</p><p><strong>Conclusion: </strong>This systematic review indicates that nerve adhesion barriers show promising outcomes in promoting nerve regeneration and functional recovery by reducing adhesion and enhancing structural alignment in peripheral nerve injuries. Applicability of such barriers in humans may still be debatable as findings are limited by the small number of included studies and predominance of animal data. Further long-term trials may warrant its' clinical efficacy.</p>","PeriodicalId":19608,"journal":{"name":"Orthopedic Research and Reviews","volume":"17 ","pages":"401-412"},"PeriodicalIF":2.3,"publicationDate":"2025-08-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12374704/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144963670","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Similar Diameter of Cutaneous Branches of the Proper Digital Nerve and Stump of the Proper Palmar Digital Nerve was a Key Factor for the Sensory Reconstruction in Short Term Outcome of Finger Pulp Defects: A Retrospective Study.","authors":"Tao Xu, Bin Wang, Yiming Lu, Renjing Qi, Yu Sun","doi":"10.2147/ORR.S533750","DOIUrl":"10.2147/ORR.S533750","url":null,"abstract":"<p><strong>Introduction: </strong>Whether an innervated reverse digital artery island flap is superior remains controversial. To date, no thorough investigation has been undertaken regarding the exact factors underlying this phenomenon. We aim to systematically summarize the innervated reverse digital artery island flap by leveraging our dataset and extract the key contributing factors.</p><p><strong>Materials and methods: </strong>A total of 79 patients from June 2016 to September 2019 who underwent innervated reverse digital artery island flap were evaluated retrospectively. Thirty nine underwent sensory nerve reconstruction with similar diameter of cutaneous branches of the proper digital nerve and stump of the proper palmar digital nerve (S-innervated group), while 40 with different diameter (D-innervated group). Sensory function was assessed by static two-point discrimination and the modified sensory evaluation standard of British Medical Research Council. Motor function was assessed by the total activity measurement. Pigmentation of the flap was also evaluated by Taylor hyperpigmentation scale. Seventy who underwent non-innervated reverse digital artery island flap at the same period was considered as the control group.</p><p><strong>Results: </strong>All 149 flaps survived completely. There was significant difference in age, operation time, time from injury to surgery, s2PD of the flap within 1 year and pigmentation between S-innervated group and Non-innervated group, while operation time and s2PD of the flap within 1 year between D-innervated group and Non-innervated group.</p><p><strong>Conclusion: </strong>The nerve diameter matching was a critical factor in innervated reverse digital artery island flap in the early restoration of sensory function and pigmentation. A significant discrepancy in nerve diameters not only compromised the intended therapeutic outcomes but also increased the incidence of neuroma formation.</p>","PeriodicalId":19608,"journal":{"name":"Orthopedic Research and Reviews","volume":"17 ","pages":"391-399"},"PeriodicalIF":2.3,"publicationDate":"2025-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12363999/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144963706","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Chris Bovinet, Ajay Antony, Nomen Azeem, Pankaj Mehta, Richard S Epter, Vivek Velagapudi, Vinicius Tieppo Francio, Christopher M Lam, Dawood Sayed
{"title":"Minimally Invasive Posterior SI Joint Fusion with a Novel Cortical Allograft: Real-World, Long-Term, Outcomes from a Large, Multisite US Cohort.","authors":"Chris Bovinet, Ajay Antony, Nomen Azeem, Pankaj Mehta, Richard S Epter, Vivek Velagapudi, Vinicius Tieppo Francio, Christopher M Lam, Dawood Sayed","doi":"10.2147/ORR.S538286","DOIUrl":"10.2147/ORR.S538286","url":null,"abstract":"<p><strong>Purpose: </strong>Sacroiliac (SI) joint dysfunction accounts for 15% to 30% of reported low back pain. Primary treatments of SI joint dysfunction include medications, bracing, physical therapy, injections, and ablations. When primary non-surgical treatments are unsuccessful, fusion or stabilization may be considered. Here, we report a multicenter study aimed to evaluate real-world outcomes of posterior sacroiliac joint fusion using cortical allograft across six United States clinical sites.</p><p><strong>Methods: </strong>Patients diagnosed with sacroiliitis through physical examination and diagnostic injection who have failed conservative management that ultimately underwent percutaneous allograft implant with at least 6 months of follow up were included. Data extracted from electronic health records included demographic and clinical characteristics, Numeric Rating Scale (NRS) pain scores, and patient-reported adverse events. Descriptive statistics were utilized to summarize baseline characteristics, and proportion of patients achieving minimally clinically important difference (MCID) was assessed. Paired t-tests were employed to compare pre-operative and post-operative outcomes.</p><p><strong>Results: </strong>A total of 258 patients were included. Of these, 63.9% were women and 36.1% were men, with a mean age of 69.2 years and an average body mass index of 29.6 kg/m². Average NRS at baseline was 7.61 ± 1.64 and 1.60 ± 1.86 (p < 0.05) at last follow-up visit. The mean pain reduction from baseline to the last follow-up (91.2 week mean or 1.75 years) was 6.01 points, exceeding MCID. The safety profile was favorable, with no serious adverse events reported in this cohort.</p><p><strong>Conclusion: </strong>Our findings affirm that posterior SI joint fusion constitutes an effective and enduring treatment option for patients suffering from SI joint dysfunction unresponsive to conservative care. The results indicate that posterior SI joint fusion is safe and effective at achieving sustained pain relief. Our findings are congruent with previously published studies and provide further evidence of sustained durable pain outcomes.</p>","PeriodicalId":19608,"journal":{"name":"Orthopedic Research and Reviews","volume":"17 ","pages":"381-390"},"PeriodicalIF":2.3,"publicationDate":"2025-08-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12360366/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144883388","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}