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Oriental Journal Of Chemistry最新文献

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Synthesis and Spectroscopy Characterizations of Some New Bis 1,3-thiazolidin-4-ones Derived from 4-hydroxybenzaldehyde Substrate 以4-羟基苯甲醛为底物的新型双1,3-噻唑烷-4-酮的合成及光谱表征
Oriental Journal Of Chemistry Pub Date : 2023-10-30 DOI: 10.13005/ojc/390508
Rojin Biro Haji*, Maher Khalid Ali, Shireen Rashid Mohammed
{"title":"Synthesis and Spectroscopy Characterizations of Some New Bis 1,3-thiazolidin-4-ones Derived from 4-hydroxybenzaldehyde Substrate","authors":"Rojin Biro Haji*, Maher Khalid Ali, Shireen Rashid Mohammed","doi":"10.13005/ojc/390508","DOIUrl":"https://doi.org/10.13005/ojc/390508","url":null,"abstract":"Over three major convenient steps, a series of some novel Bis-Schiff bases, and Bis 1,3-thiazolidin-4-one derivatives have been synthesized: Firstly, the etherification process through the reaction of the 4-hydroxybenzaldehyde substrate with o-, m-, and p-chlorobenzylchlorides under mild circumstances. Secondly, the condensation reaction between 4-((chlorobenzyl)oxy)benzaldehyde compounds with a number of aromatic diamines in an acidic environment produces the required Bis-Schiff intermediates. Finally, the practical cyclization step was finished by synthesizing the required Bis 1,3-thiazolidin-4-one products with 79-97% yields through refluxing reaction in benzene with thioglycolic acid.","PeriodicalId":19599,"journal":{"name":"Oriental Journal Of Chemistry","volume":"9 3","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136068901","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparative Phytochemical Analysis of Kanakasava, Kanakasava Distillate, and Kanakasava Nebulizer Solution Using Gas Chromatography-Mass Spectrometry (GC-MS) 气相色谱-质谱联用技术对比分析川芎、川芎馏出液和川芎雾化液的植物化学成分
Oriental Journal Of Chemistry Pub Date : 2023-10-30 DOI: 10.13005/ojc/390532
Deshpande Shailesh V, Rashmi Chojer, Deshpande Vaishali S
{"title":"Comparative Phytochemical Analysis of Kanakasava, Kanakasava Distillate, and Kanakasava Nebulizer Solution Using Gas Chromatography-Mass Spectrometry (GC-MS)","authors":"Deshpande Shailesh V, Rashmi Chojer, Deshpande Vaishali S","doi":"10.13005/ojc/390532","DOIUrl":"https://doi.org/10.13005/ojc/390532","url":null,"abstract":"Introduction: Kanakasava is the classical formulation known to have beneficial effects on bronchial asthma. This study deals with the objective to compare the phytochemicals present in Kanakasava, Kanakasava distillate, and Kanakasava nebulizer solution using gas chromatography-mass spectrometry (GC-MS) and to determine if Kanakasava nebulizer solution can be useful in managing respiratory diseases. Methods: Kanakasava, Kanakasava distillate and Kanakasava nebulizer solution were prepared accordingly and standard GC-MS analysis was performed on the samples. Results: The GC-MS analysis indicated the presence of 6, 13 and 10 important phytochemicals in Kanakasava, Kanakasava distillate and Kanakasava nebulizer solution respectively. Many chemicals acting on the respiratory system were found in all three forms of Kanakasava and some of the chemicals were having similar actions. Conclusion: Despite the fact that the phytochemicals found in the three of them differed due to molecular fragmentation during the whole process, the efficacy of the novel Kanakasava nebulizer solution remained unaffected.","PeriodicalId":19599,"journal":{"name":"Oriental Journal Of Chemistry","volume":"346 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136105375","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Exploring the Expanding Frontiers: The Promising Role of Supramolecules in Advancing Cancer and Infectious Disease Therapy 探索不断扩大的前沿:超分子在推进癌症和传染病治疗中的有希望的作用
Oriental Journal Of Chemistry Pub Date : 2023-10-30 DOI: 10.13005/ojc/390502
Nirali Parmar, Keyur Bhatt
{"title":"Exploring the Expanding Frontiers: The Promising Role of Supramolecules in Advancing Cancer and Infectious Disease Therapy","authors":"Nirali Parmar, Keyur Bhatt","doi":"10.13005/ojc/390502","DOIUrl":"https://doi.org/10.13005/ojc/390502","url":null,"abstract":"The use of calixpyrrole derivatives as potential anticancer and antibacterial agents has recently gained significant attention. We summarise recent advances in the design and production of calixpyrrole-based compounds as well as their biological actions against cancer and bacterial cells, in this overview. The structure-activity relationships (SAR) of these compounds and their mechanisms of action are discussed, highlighting their potential as therapeutic agents. Furthermore, we discuss the challenges and opportunities associated with the development of calixpyrrole-based agents as effective anticancer and antibacterial drugs. Overall, this review provides valuable insights into the development of novel calixpyrrole-based compounds with potent anticancer and antibacterial activities, which could have the way for the development of new therapeutics with improved efficacy and reduced toxicity.","PeriodicalId":19599,"journal":{"name":"Oriental Journal Of Chemistry","volume":"191 ","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136068746","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Recent Monitoring of Ground Water Quality in and Around Industrial Area of Vellore City at Two Different Monsoon Periods, South India 两个不同季风期印度南部Vellore市工业区及其周边地区地下水水质的近期监测
Oriental Journal Of Chemistry Pub Date : 2023-10-30 DOI: 10.13005/ojc/390510
M. Sangeetha Priya, A. Thaminum Ansari, V. Kanchana
{"title":"Recent Monitoring of Ground Water Quality in and Around Industrial Area of Vellore City at Two Different Monsoon Periods, South India","authors":"M. Sangeetha Priya, A. Thaminum Ansari, V. Kanchana","doi":"10.13005/ojc/390510","DOIUrl":"https://doi.org/10.13005/ojc/390510","url":null,"abstract":"The present study focuses on the assessment of seasonal variation in groundwater quality of in and around industrial area of Vellore City. The samples were collected seasonally and are categorized as premonsoon, monsoon and post-monsoon during April 2022 and March 2023. Eighteen physicochemical parameters were assessed for forty eight different samples collected along the region of in and around industrial area of Vellore City at two different Monsoon periods. The analysis of the water quality parameters, including pH, EC, TDS, Ca2+, Mg2+, Na+, K+, Cl-, HCO3-, CO32-, SO42-, and heavy metals, was done in accordance with BIS and WHO standards. The results of these surveys were used to pinpoint the geochemical processes taking place in this area. According to the analytical findings, there were significant variations in the water quality inclinations between samples and locations. Water management and treatment policy decisions can be made with the support of water quality analysis which can also help to identify potential health issues.","PeriodicalId":19599,"journal":{"name":"Oriental Journal Of Chemistry","volume":"63 4","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136068898","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Synthesis, Characterization and Evaluation of Antimicrobial Properties of Novel Oxazine and Thiazine Compounds Derived from Chalcones 新型查尔酮类恶嗪类和噻嗪类化合物的合成、表征及抗菌性能评价
Oriental Journal Of Chemistry Pub Date : 2023-10-30 DOI: 10.13005/ojc/390530
Shreekant. M. Prajapati, Sanjay. S. Shah, Arun .R. Malaviya
{"title":"Synthesis, Characterization and Evaluation of Antimicrobial Properties of Novel Oxazine and Thiazine Compounds Derived from Chalcones","authors":"Shreekant. M. Prajapati, Sanjay. S. Shah, Arun .R. Malaviya","doi":"10.13005/ojc/390530","DOIUrl":"https://doi.org/10.13005/ojc/390530","url":null,"abstract":"In this ongoing research, our objective is to synthesize Oxazines and Thiazines by employing Chalcones, providing an uncomplicated approach for generating diverse heterocyclic derivatives. These substances show a wide spectrum of biological impact, i.e. analgesic, anti-phlogistic, and anti-convulsant properties. To characterize these newly synthesized compounds, we conducted comprehensive analyses employing techniques such as infrared spectroscopy (IR), proton nuclear magnetic resonance (1H NMR), carbon-13 nuclear magnetic resonance (13C NMR), and mass spectrometry. Additionally, we evaluated the antimicrobial potential of these compounds.","PeriodicalId":19599,"journal":{"name":"Oriental Journal Of Chemistry","volume":"23 253","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136068032","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Synthesis and Biofunctional Evaluation of Novel Isoxazole, C-Nucleoside, and Thioxopyrimidine Derivatives 新型异恶唑、c -核苷和硫代嘧啶衍生物的合成和生物功能评价
Oriental Journal Of Chemistry Pub Date : 2023-10-30 DOI: 10.13005/ojc/390526
Rajendra K. Wanare, Rajendra R. Tayade, Abhilash A. Sukhadeve, Prafulla P. Choudhari, R. G. Mahakale, Nihal Mishra
{"title":"Synthesis and Biofunctional Evaluation of Novel Isoxazole, C-Nucleoside, and Thioxopyrimidine Derivatives","authors":"Rajendra K. Wanare, Rajendra R. Tayade, Abhilash A. Sukhadeve, Prafulla P. Choudhari, R. G. Mahakale, Nihal Mishra","doi":"10.13005/ojc/390526","DOIUrl":"https://doi.org/10.13005/ojc/390526","url":null,"abstract":"Thioxopyrimidines are an important class of compounds in the fields of biology and chemistry that play significant roles in drug discovery, nucleic acid chemistry, enzyme inhibition, and various other fields of science and technology. Their structural diversity and potential bioactivities make them valuable tools for researchers. This work presents a thorough synthesis and analysis and bio-functional assessment of a variety of isoxazole C-Nucleoside, and thioxopyrimidine derivative. The structural characterization of the synthesized compounds was achieved through spectral analyses, including IR, 1H NMR, and mass spectra and also deals with its antibacterial and antifungal activity.","PeriodicalId":19599,"journal":{"name":"Oriental Journal Of Chemistry","volume":"16 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136068035","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Thickening Performance Evaluation and Molecular Dynamics Simulation on Hydrophobic Associated Polymer in Acid Circumstances 疏水缔合聚合物在酸性环境下的增稠性能评价及分子动力学模拟
Oriental Journal Of Chemistry Pub Date : 2023-10-30 DOI: 10.13005//ojc/390501
Xianwu Jing, Youquan Liu, Lang Zhou, Pengfei Zhang, Jian Lan, Jie Qi, Shanshan Dai, Hongsheng Lu
{"title":"Thickening Performance Evaluation and Molecular Dynamics Simulation on Hydrophobic Associated Polymer in Acid Circumstances","authors":"Xianwu Jing, Youquan Liu, Lang Zhou, Pengfei Zhang, Jian Lan, Jie Qi, Shanshan Dai, Hongsheng Lu","doi":"10.13005//ojc/390501","DOIUrl":"https://doi.org/10.13005//ojc/390501","url":null,"abstract":"Acid thickener is of necessity for improving the exploitation capacity for oil and gas resources of carbonate reservoirs. Here a hydrophobic associated polymer (HPA) by introducing a nonionic hydrophobic monomer (AO) was designed as the acid thickener. The experimental results demonstrated that HPA suggests excellent acid resistance, shear resistance, and thermal stability attributing to the gradual exposure of hydrophobic chain to H2O circumstances that enhances the strength of hydrophobic association. The square radius of gyration of HPA raises with the introduction of AO confirming the unfold of HPA by intermolecular hydrophobic association, which strengthens the network structure. The decrease of mean square displacement and diffusion coefficient of H2O and H3O+ molecules suggest the enhancement for network structure by hydrophobic chain owing to HPA hindered the diffusion of H2O and H3O+ molecules. These findings are expected to supply a guidance for the design and research on the acid thickener.","PeriodicalId":19599,"journal":{"name":"Oriental Journal Of Chemistry","volume":"4 ","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136069415","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Practical Approach for Solubility Enhancement of Leflunomide 一种提高来氟米特溶解度的实用方法
Oriental Journal Of Chemistry Pub Date : 2023-10-30 DOI: 10.13005/ojc/390537
Yash Bhandari, Sunayana Rathore, Vaishali Raghuwanshi, Shehnaz Sheikh, Yashmita Sharma, Ishan Dubey
{"title":"A Practical Approach for Solubility Enhancement of Leflunomide","authors":"Yash Bhandari, Sunayana Rathore, Vaishali Raghuwanshi, Shehnaz Sheikh, Yashmita Sharma, Ishan Dubey","doi":"10.13005/ojc/390537","DOIUrl":"https://doi.org/10.13005/ojc/390537","url":null,"abstract":"Leflunomide is an anti-rheumatic medication. As it has low water solubility, it shows low absorption in gastrointestinal tract. The reported solubility of Leflunomide is approx 25.27 mcg/ml. Leflunomide comes under BCS Class II in which it has low solubility and high permeability. In this study, gel entrapment technique is used to enhance the solubility of leflunomide. In this technique Hydroxy Propyl Methyl Cellulose and Ethyl Cellulose are used which are converted to gel with the addition of different organic solvent such as Ethanol, Chloroform, Di chloro Methane etc. The analyses of the samples are done by UV Spectrophotometer at 260nm. Results shows an increment in solubility of Leflunomide drug by gel entrapment technique and are found to be 5.23, 3.80, 3.05 and 2.64 times using HPMC+Chloroform, HPMC+Ethanol+ Dichloro methane, HPMC+Ethanol+Water, HPMC+Ethyl Cellulose+ Dichloro methane+ Water respectively.","PeriodicalId":19599,"journal":{"name":"Oriental Journal Of Chemistry","volume":"100 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136105555","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Analysis of Pyrostegia Venusta Flower Mediated Dye as Sensitizer for TiO2 Based Dye Sensitized Solar Cells 火豆花介导染料作为TiO2基染料敏化太阳能电池的敏化剂分析
Oriental Journal Of Chemistry Pub Date : 2023-10-30 DOI: 10.13005/ojc/390529
Tanvi Pandya, Varsha Rajoriya, Jay Lalita, K. R. Genwa
{"title":"The Analysis of Pyrostegia Venusta Flower Mediated Dye as Sensitizer for TiO2 Based Dye Sensitized Solar Cells","authors":"Tanvi Pandya, Varsha Rajoriya, Jay Lalita, K. R. Genwa","doi":"10.13005/ojc/390529","DOIUrl":"https://doi.org/10.13005/ojc/390529","url":null,"abstract":"Since no vacuum systems or expensive equipment are needed in their fabrication, dye sensitized solar cells (DSSCs) are anticipated to be one of the effective solar cells of third generation delivering green energy at low production costs. The structure and operating principles of the dye-sensitized solar cell (DSSC) are reviewed in this work. Optical characterization and extraction of detail is provided on pyrostegia venusta. The preparation steps, dye-based optical and electrical characterization of the DSSC, are all covered. The sensitized solar cell having maximum conversion efficiency(1.99%)is capable of producing an open circuit voltage Voc (1.94V) and a short circuit current isc (1.804mA) when exposed to solar irradiation.","PeriodicalId":19599,"journal":{"name":"Oriental Journal Of Chemistry","volume":"81 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136068016","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Study on Solution Behavior of Green Gemini-Conventional Mixed Systems and their Solubilization Capability Towards Phenanthrene 绿色双-常规混合体系的溶解行为及其对菲的增溶能力研究
Oriental Journal Of Chemistry Pub Date : 2023-10-30 DOI: 10.13005/ojc/390514
Moughes Ahmad, Najam Sardar
{"title":"Study on Solution Behavior of Green Gemini-Conventional Mixed Systems and their Solubilization Capability Towards Phenanthrene","authors":"Moughes Ahmad, Najam Sardar","doi":"10.13005/ojc/390514","DOIUrl":"https://doi.org/10.13005/ojc/390514","url":null,"abstract":"In the present study green ester bonded cationic gemini surfactants, Ethane-1,2-diyl bis (N,N-dimethyl-N-hexadecylammonium acetoxy)dichloride (16E216) and 2,2’-{(oxybis(ethane1,2-diyl)bis(oxy)bis(N-alkyl-N,N-dimethyl-2-hexadecyl oxoethanaminium)dichloride (16E316) were synthesized and evaluated for their various physicochemical and other interaction parameters with their mixtures with conventional surfactants namely (cetyltrimethylammonium bromide (CTAB) and cetyltrimethylammonium chloride (CTAC) by tensiometry. Much lower cmc values of the order of 250 times were observed for 16E216 and 16E316 than conventional surfactants. Further, synergistic interaction occurs between the gemini and conventional surfactants as a result of negative interaction parameters. The mixed systems were also investigated for the solubilization of polyaromatic hydrocarbon (PAH), Phenanthrene. Among the pure surfactants, 16E216 has the highest and CTAB has the lowest efficiency for phenanthrene. Solubility enhancement was observed for almost all gemini-conventional mixed systems and shows better solubilization properties than pure surfactant systems due to synergism. The morphologies of pure and mixed systems were examined by TEM imaging. Findings of the present study could be exploited to use such mixed surfactant systems as the successful remediation technology for PAH contaminated soils.","PeriodicalId":19599,"journal":{"name":"Oriental Journal Of Chemistry","volume":"26 ","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136068944","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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