Oriental Journal Of Chemistry最新文献

{"title":"Direct Enantiomeric Separation of Indapamide by Thin Layer Chromatography using B- Cyclodextrin as Chiral Selector","authors":"Manju Bala, Sonika Sethi, Priyanka Sharma","doi":"10.13005/ojc/390636","DOIUrl":"https://doi.org/10.13005/ojc/390636","url":null,"abstract":"A novel economic thin layer chromatographic method for stereoselective separation of racemic mixture of (RS)-Indapamide and determination of their enantiomers was done. The method was based on using normal TLC plates and  cyclodextrin with hydroxylic part, was used as the chiral selector. Cyclodextrin was used as an additive in silica gel to prepare a TLC plate which was a non-covalent bonding, and there was no chiral substance added in the solvent system. The mobile phase was toluene-ethyl acetate-MeOH-glacial AcOH (6:4:1:0.1). Cyclodextrin was also added to mobile phase, and there was no chiral selector in the stationary phase. The mobile phase was a mixture of toluene-ethyl acetate-MeOH-glacial AcOH – 5mM CD (6:4:1:0.1:1.0). The spots were then isolated and identified. The impact of the componentsofmobile phase, temperature, and pHwas studied for the finding the best separation conditions. The spots were sited in a chamber which had Iodine granules.","PeriodicalId":19599,"journal":{"name":"Oriental Journal Of Chemistry","volume":"82 2","pages":""},"PeriodicalIF":0.5,"publicationDate":"2023-12-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139153945","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of Comparative Metabolomic Profile in Cardamom elettaria and Amomum subulatum Fruits","authors":"Arun Gopinath, Sangilimuthu Alagar Yadav, Ranjithkumar D","doi":"10.13005/ojc/390632","DOIUrl":"https://doi.org/10.13005/ojc/390632","url":null,"abstract":"Background: Cardamom is Queen of Spices belonging to Zingiberaceae family. The present study to reveals the comparative metabolomic profile of the two different types of cardamom such as Cardamom elettaria and Amomum subulatum. Methods: Physical parameters and chemical parameters were screened in both species. The essential oil was extracted by using Clevenger apparatus and analysed the volatile profile by GC-MS studies. Results: Capsule of C. elettaria was observed to dominant in bulk density and volatile oil content whereas A. subulatum is greater in size and shape. Oil of C. elettaria showed the good ascent of Optical rotation (+29.1), Specific gravity (1.4620), refractive index (0.927), aroma and taste. In C. elettaria and A. subulatum the terpinyl acetate, geranyl acetate, and myrcene were present in high level. As well, 1,8-cineole, pinene, 3-carene, and terpineol are the primary differentiators in both seeds with diverse therapeutic effects. Conclusion: The physico-chemical characteristics of C. elettaria and A. subulatum were contrasted in this work. α-terpinyl acetate is a lead molecule in C. elettaria. 1,8-cineoleare is rich in both essential oils. Future researchers and flavourists can use this study to improve the scent and therapeutic elements of drug repurposing.","PeriodicalId":19599,"journal":{"name":"Oriental Journal Of Chemistry","volume":"79 s1","pages":""},"PeriodicalIF":0.5,"publicationDate":"2023-12-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139153958","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Emergence of CaO-MgO based Binary Oxides of Alkaline Earth Metals as Cost-effective Solid Base Heterogeneous Catalysts and Sorbents: (A Mini Review)","authors":"Siddaramagoud Bandalla, Satyanarayana Mavurapu, S. Jonnalagadda, Chandrashekar Vasam","doi":"10.13005/ojc/390602","DOIUrl":"https://doi.org/10.13005/ojc/390602","url":null,"abstract":"The mono or single oxides of alkaline earth metals such as CaO and MgO are a type of non-toxic and non-corrosive solid-base heterogeneous catalysts. Nevertheless, these mono oxide particles can agglomerate and form larger and less active particles at certain temperatures and reduces their catalytic activity. Therefore, the use of thermally stable CaO-MgO binary oxides is recommended. Further, the possible synergistic interactions between two metal centers provides cooperative catalytic behavior to improve catalytic activity compared to their single oxide counterparts. Therefore, the main theme of this review article is to highlight the ability of reported CaO-MgO based alkaline earth binary oxides as cost-effective and efficient solid-base catalysts in variety of organic transformations and to expand their scope in many other unexplored non-asymmetric organic transformations. Literature survey reveals that CMBOs are highly considerable in optimizing recognized organic transformations such as Transesterification, Knoevenagel/Aldol condensations, Isomerization, Oligomerization, Acetylation, Henry reaction, Alcoholysis, Aza-Michael addition, Cracking of Alkanes, H2-production via steam reforming, Photodegradation of organic pollutants and so forth. The literature survey further visualizes that the surface properties of CMBOs such as Brønsted/ Lewis’s basicity, surface area, particle size, structural diversity, Ca: Mg ratios and synergism between Ca and Mg in CMBOs are very useful to promote them as efficient catalysts compared to their single oxide counterparts (pure CaO and pure MgO). The rightness of proposed mechanisms of abovementioned organic reactions by CMBO catalysts is elicited by this review. Moreover, the precursors for CMBOs are inexpensive, highly abundant and eco-compatible. Apart from the catalytic applications, the suitability of the CMBOs in sorption studies including CO2 uptake, ethanol steam reforming, and heavy metal ion removal is also covered.","PeriodicalId":19599,"journal":{"name":"Oriental Journal Of Chemistry","volume":"12 45","pages":""},"PeriodicalIF":0.5,"publicationDate":"2023-12-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139154516","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bi-functional Cold Brand Reactive Dyes with Urea as a Bridge Group: Synthesis, Characterization and Dyeing Performance on Various Fibers.","authors":"Gaurav K. Rathod, Bhavesh M. Patel, K. Parmar, Divyesh R. Patel","doi":"10.13005/ojc/390637","DOIUrl":"https://doi.org/10.13005/ojc/390637","url":null,"abstract":"Bi-functional reactive dyes from the Cold brand that have exceptional dyeing capabilities. The intermediate for bi-functional cold-brand reactive dyes is 3, 3’-Disulpho-4, 4’-diamino diphenyl urea, which is synthesized through the interaction of one mole of urea aqueous solution with two moles of 1, 4-diaminobenzene-2-sulphonic acid. In this bi-functional reactive dye system, urea was utilized as a bridge molecule to give the reactive dyes significant water solubility. Incorporating various cyanurated coupling components, different colors are produced. It has good dyeing properties and provides a wide spectrum of shades on various fibres.","PeriodicalId":19599,"journal":{"name":"Oriental Journal Of Chemistry","volume":"165 2","pages":""},"PeriodicalIF":0.5,"publicationDate":"2023-12-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139152977","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Kinetic Study and Hammett Correlations in the Chemistry of M-Nitro and M-Amino Benzoic Acid Hydrazides by Using Thallium (Iii) in 1,4-Dioxane Medium","authors":"Samadhan H. Nikalaje, A. Varale","doi":"10.13005/ojc/390626","DOIUrl":"https://doi.org/10.13005/ojc/390626","url":null,"abstract":"Iodometric analysis is used to determine the kinetics and mechanism of oxidation of benzoic, m-amino, and m-nitro benzoic acid hydrazides by Thallium(III) in acidic medium at constant ionic strength. The complex decomposes to produce the product. The rate of the reaction is decreased by the rise in [H+] and [Cl-]. Additionally, Activation parameters were established, and a mechanism is proposed. The analysis of reaction constants (ρ) and substituent constants (σ) for m-nitro BAH and m-amino BAH indicates good agreement with the values from the literature.","PeriodicalId":19599,"journal":{"name":"Oriental Journal Of Chemistry","volume":"68 3","pages":""},"PeriodicalIF":0.5,"publicationDate":"2023-12-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139153172","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Synthesis of Novel Organic Compound as Corrosion Inhibitor in Hydrochloric acid Medium-A Comparative Study","authors":"M. Vimala, Vchandrasekaran V","doi":"10.13005/ojc/390612","DOIUrl":"https://doi.org/10.13005/ojc/390612","url":null,"abstract":"A novel organic compound derivativeof Benzothiazole,BFCPA[N- Substitued-1,3-benzo-thiazol-2pheny-2-[4-(furan-2-carbonyl)piperazin-1-phenyl] acetamidehas beensynthesizied and used as inhibitor on mild steelcorrosion in 1N and 2N HCl acidic medium.Using this inhibitor the rate of orrosion and inhibitor efficiency was analysed by mass loss data and electrochemical analysis.Byincreasing concentration of the inhibitor BFCPA exhibits good corrosion inhibition effectiveness less corrosion rate shows the electron donating property.The structure of BFCPA has been confirmed using various spectral studies. Based on adsorption studies it reveals Langmuir adsorption isotherm.","PeriodicalId":19599,"journal":{"name":"Oriental Journal Of Chemistry","volume":"103 4","pages":""},"PeriodicalIF":0.5,"publicationDate":"2023-12-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139154089","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"RP-HPLC Method for Content of Genotoxic 4-methoxybenzyl Chloride in Venlafaxine","authors":"Santosh T. Khadangale, Vitthal M. Dhalape, Rahul V. Pinjari","doi":"10.13005/ojc/390629","DOIUrl":"https://doi.org/10.13005/ojc/390629","url":null,"abstract":"Venlafaxine, primarily available in dosage in Venlafaxine hydrochloride (VEN∙HCl) form, is a discriminating serotonin and norepinephrine reuptake inhibitor (SNRI) anti-depressant drug. The 4-methoxybenzyl chloride (4-MBC) is a genotoxic impurity present in VEN∙HCl. A reverse-phase high-performance liquid chromatography (RP-HPLC) method is developed for the determination of 4-MBC content this method is validated employing ICH (International Council on Harmonisation) guidelines. During the method development, Purospher STAR end-capped (250mm x 4.0mm), 5µm HPLC column, and gradient profile for mobile phase with constant 1.0 mL/min flow rate are used. Mobile phase A is a buffer of pH 8.5 containing 0.1% v/v of liquid ammonia in water with adjusted pH using 10% orthophosphoric acid, whereas mobile phase B is acetonitrile. The injection volume, column oven temperature, and autosampler temperature were 50 µL, 55 °C, and 5 °C, respectively. The data is acquired at 225 nm wavelength. The method yields a well-separated peak of 4-MBC from Venlafaxine and its impurities. This method is linear in the range of LOQ to 150% level of specification concentration of impurity and the observed correlation coefficient is 0.999. The repeatability and intermediate precision are evaluated and the respective values of %RSD for 4-MBC content are 0.43 and 0.93. Robustness studies show insignificant change for the system suitability criteria like %RSD, theoretical plates, and tailing factor, their values being well within the acceptance limit. The new method for the quantification of genotoxic impurity 4-MBC is precise, sensitive, rugged, and accurate; it also qualifies all the criteria of stability, linearity, and robustness.","PeriodicalId":19599,"journal":{"name":"Oriental Journal Of Chemistry","volume":"101 13","pages":""},"PeriodicalIF":0.5,"publicationDate":"2023-12-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139154124","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cu2ZnSnS4 Thin Film Solar Cell Construction Using Chemical Technique","authors":"Kishore Kumar Y B, Suresh Babu G, Swapna Smitha A S, Surya Sekhar Reddy M, Kiran Y B","doi":"10.13005/ojc/390622","DOIUrl":"https://doi.org/10.13005/ojc/390622","url":null,"abstract":"Cu2ZnSnS4 (CZTS) presents itself as a potential quaternary semiconductor absorber layer in the field of thin film heterojunction solar cells. The conventional spray pyrolysis method has been used in the present investigation. X-ray diffraction results confirm the structure of the deposited films as kesterite. The lattice parameters are determined to be a = 0.5436 nm and c = 1.0856 nm. The material exhibits an energy gap of 1.5 eV and an optical absorption coefficient exceeding 104 /cm. CZTS films exhibit a p-type nature. The deposited films are kept on the hot surface for some time after the chemical spray pyrolysis is finished, which contributes to improved crystallinity. Using chemical synthesis techniques, a Cu2ZnSnS4 thin film solar cell is constructed. These solar cells exhibited an efficiency of 0.5%. Ongoing efforts are directed towards achieving reasonable efficiency levels.","PeriodicalId":19599,"journal":{"name":"Oriental Journal Of Chemistry","volume":"101 4","pages":""},"PeriodicalIF":0.5,"publicationDate":"2023-12-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139154139","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Structural and Functional Dynamics of Secondary Metabolite from Actinokineospora cibodasensis against Pseudomonas aeruginosa Biofilm","authors":"Sreelakshmi K.S, U. R","doi":"10.13005/ojc/390619","DOIUrl":"https://doi.org/10.13005/ojc/390619","url":null,"abstract":"Biofilm formation has incredible detrimental effects and has brought huge issue to our daily life. Pseudomonas aeruginosa is recognized as an opportunistic pathogen and its one of the antibiotic resistance mechanisms includes biofilm formation. To survive against harsh environmental conditions the microorganisms form an extracellular polymeric substance matrix. Natural products, particularly, marine natural products have been established useful in providing new chemical entities to mark biofilm inhibition and dole out as a rich source of privileged frames for studying chemical as well as biological applications. In the present study, antibiofilm potential of bioextract from Actinokineospora cibodasensis (MW513387) is tested against Pseudomonas aeruginosa (ATCC 27853) biofilm. The analysis of the quorum sensing modulation was done using exopolysaccharide (EPS) quantification and Cytotoxicity assays were performed to check toxicity. Scanning electron microscopy (SEM) was also conducted to visualize the mitigation of biofilm using the biocontrol agent. All the assays conducted evidently indicated that the potential bioactive compound from Actinokineospora cibodasensis has greater inhibition effect against pathogenic biofilm. In the near-term years it is expected that these pharmaceutical compounds from natural source be translated into antibiofilm drugs.","PeriodicalId":19599,"journal":{"name":"Oriental Journal Of Chemistry","volume":"21 8","pages":""},"PeriodicalIF":0.5,"publicationDate":"2023-12-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139153345","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Synthesis, Characterization, and Computational Study of Novel 2-Phenoxyethyl Xanthate Ligand and Complexes with some Transitions Metals","authors":"Mohammed Mahmoud Molla-Babaker, Maher Khalid, Saad.e. Al-mukhtar Al-mukhtar","doi":"10.13005/ojc/390616","DOIUrl":"https://doi.org/10.13005/ojc/390616","url":null,"abstract":"The research focuses on the synthesis and characterization of a novel xanthate ligand and their complexes with the formula [M(PhOEtXant)2], where M represents as Mn(II), Fe(II), Co(II), Ni(II), Cu(II), and Zn(II), and PhOEtXant stands for 2-Phenoxyethylxanthate. The antioxidant activities of these complexes will be evaluated by comparing them with standard natural antioxidants and ascorbic acid using the (DPPH) assay. The synthesized complexes were thoroughly characterized based on their physical properties using various spectral methods, like XRD, FTIR, NMR, AA, UV-visible, magnetic properties, and conductivity measurements. The complexes are nonelectrolytes, according to molar conductance measurements. Infrared spectra revealed that the ligand acts as a neutral bidentate moiety in all the compounds. Electronic spectra and effective magnetic moments suggested that the compounds exhibit a tetrahedral shape, which is supported by the experimental data. For further insights into the geometry, bond length, bond angle, electronic characteristics, and thermodynamic factors of the synthesized compounds, a density functional theory (DFT) approach with the basis set GGA-PBE was employed for optimization. The antioxidant evaluation using the DPPH assay demonstrated that all the complexes displayed significant radical scavenging activity when compared to the standard ascorbic acid. Remarkably, the Cu, Zn, Ni, and Mn complexes showed superior radical scavenging activities compared to the other complexes and the standard ascorbic acid. Overall, this research highlights the promising potential of the synthesized complexes as effective antioxidants, showcasing their value for further exploration in various applications related to antioxidant research and potentially in therapeutic contexts. The comprehensive characterization using a range of spectroscopic and computational techniques provides valuable insights into their structure and properties, supporting their potential applications in diverse fields of chemistry.","PeriodicalId":19599,"journal":{"name":"Oriental Journal Of Chemistry","volume":"7 2","pages":""},"PeriodicalIF":0.5,"publicationDate":"2023-12-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139153380","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}