新型异恶唑、c -核苷和硫代嘧啶衍生物的合成和生物功能评价

IF 0.6 Q4 CHEMISTRY, MULTIDISCIPLINARY

Oriental Journal Of Chemistry Pub Date : 2023-10-30 DOI:10.13005/ojc/390526

Rajendra K. Wanare, Rajendra R. Tayade, Abhilash A. Sukhadeve, Prafulla P. Choudhari, R. G. Mahakale, Nihal Mishra

{"title":"新型异恶唑、c -核苷和硫代嘧啶衍生物的合成和生物功能评价","authors":"Rajendra K. Wanare, Rajendra R. Tayade, Abhilash A. Sukhadeve, Prafulla P. Choudhari, R. G. Mahakale, Nihal Mishra","doi":"10.13005/ojc/390526","DOIUrl":null,"url":null,"abstract":"Thioxopyrimidines are an important class of compounds in the fields of biology and chemistry that play significant roles in drug discovery, nucleic acid chemistry, enzyme inhibition, and various other fields of science and technology. Their structural diversity and potential bioactivities make them valuable tools for researchers. This work presents a thorough synthesis and analysis and bio-functional assessment of a variety of isoxazole C-Nucleoside, and thioxopyrimidine derivative. The structural characterization of the synthesized compounds was achieved through spectral analyses, including IR, 1H NMR, and mass spectra and also deals with its antibacterial and antifungal activity.","PeriodicalId":19599,"journal":{"name":"Oriental Journal Of Chemistry","volume":"16 1","pages":"0"},"PeriodicalIF":0.6000,"publicationDate":"2023-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Synthesis and Biofunctional Evaluation of Novel Isoxazole, C-Nucleoside, and Thioxopyrimidine Derivatives\",\"authors\":\"Rajendra K. Wanare, Rajendra R. Tayade, Abhilash A. Sukhadeve, Prafulla P. Choudhari, R. G. Mahakale, Nihal Mishra\",\"doi\":\"10.13005/ojc/390526\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Thioxopyrimidines are an important class of compounds in the fields of biology and chemistry that play significant roles in drug discovery, nucleic acid chemistry, enzyme inhibition, and various other fields of science and technology. Their structural diversity and potential bioactivities make them valuable tools for researchers. This work presents a thorough synthesis and analysis and bio-functional assessment of a variety of isoxazole C-Nucleoside, and thioxopyrimidine derivative. The structural characterization of the synthesized compounds was achieved through spectral analyses, including IR, 1H NMR, and mass spectra and also deals with its antibacterial and antifungal activity.\",\"PeriodicalId\":19599,\"journal\":{\"name\":\"Oriental Journal Of Chemistry\",\"volume\":\"16 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.6000,\"publicationDate\":\"2023-10-30\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Oriental Journal Of Chemistry\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.13005/ojc/390526\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"CHEMISTRY, MULTIDISCIPLINARY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Oriental Journal Of Chemistry","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.13005/ojc/390526","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"CHEMISTRY, MULTIDISCIPLINARY","Score":null,"Total":0}

引用次数: 0

摘要

硫代嘧啶是生物和化学领域中一类重要的化合物，在药物发现、核酸化学、酶抑制等科学技术领域发挥着重要作用。它们的结构多样性和潜在的生物活性使它们成为研究人员的宝贵工具。本文对多种异恶唑c -核苷和硫氧嘧啶衍生物进行了全面的合成分析和生物功能评价。通过IR、1H NMR和质谱等光谱分析对合成化合物进行了结构表征，并对其抗菌和抗真菌活性进行了研究。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

查看原文本刊更多论文

Synthesis and Biofunctional Evaluation of Novel Isoxazole, C-Nucleoside, and Thioxopyrimidine Derivatives

Thioxopyrimidines are an important class of compounds in the fields of biology and chemistry that play significant roles in drug discovery, nucleic acid chemistry, enzyme inhibition, and various other fields of science and technology. Their structural diversity and potential bioactivities make them valuable tools for researchers. This work presents a thorough synthesis and analysis and bio-functional assessment of a variety of isoxazole C-Nucleoside, and thioxopyrimidine derivative. The structural characterization of the synthesized compounds was achieved through spectral analyses, including IR, 1H NMR, and mass spectra and also deals with its antibacterial and antifungal activity.

求助全文

通过发布文献求助，成功后即可免费获取论文全文。去求助

来源期刊

Oriental Journal Of Chemistry CHEMISTRY, MULTIDISCIPLINARY-

自引率

20.00%

发文量

172

期刊介绍： Oriental Journal of Chemistry was started in 1985 with the aim to promote chemistry research. The journal consists of articles which are rigorously peer-reviewed. The journal was indexed in Emerging Science citation index in 2016. The Editorial board member consists of eminent international scientist in all fields of Chemistry. Details of each member and their contact information is mentioned in website. The journal has thorough ethics policies and uses plagiarism detection software(ithenticate) to screen each submission. The journal has recently partnered with publons as a part of making our reviews more transparent. The journal has recently incorporated PlumX for article level matrix. The journal is promoting research on all social and academic platforms mentioned in PlumX guidelines. The journal uses google maps to improve on the geographical distribution of Editorial board members as well as authors.