Ophthalmic Plastic and Reconstructive Surgery最新文献

{"title":"Atlas of Lacrimal Drainage Disorders (2nd Edition).","authors":"","doi":"10.1097/IOP.0000000000002826","DOIUrl":"https://doi.org/10.1097/IOP.0000000000002826","url":null,"abstract":"","PeriodicalId":19588,"journal":{"name":"Ophthalmic Plastic and Reconstructive Surgery","volume":"41 2","pages":"238"},"PeriodicalIF":1.2,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143557383","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Orbital Inflammatory Disease as a Presenting Symptom of Generalized Lipodystrophy in a Young Female.","authors":"Julie M Shabto, Amy R Shteyman, Shanlee Stevens, Allison Coombs, Michael Kazim","doi":"10.1097/IOP.0000000000002823","DOIUrl":"10.1097/IOP.0000000000002823","url":null,"abstract":"<p><p>The authors report the first case of generalized lipodystrophy with orbital inflammatory symptoms. A 6-year-old female with hypothyroidism who developed hepatosplenomegaly, lymphadenopathy, and progressive loss of subcutaneous fat. Following flu vaccination, she developed orbital inflammatory symptoms. Imaging of the orbits demonstrated a paucity of retrobulbar fat and fat stranding. Systemic workup revealed insulin resistance and hepatosteatosis, consistent with generalized lipodystrophy. The authors discuss the typical history and examination findings in generalized lipodystrophy and review the etiology, treatment options, and outcomes.</p>","PeriodicalId":19588,"journal":{"name":"Ophthalmic Plastic and Reconstructive Surgery","volume":" ","pages":"e54-e56"},"PeriodicalIF":1.2,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142668502","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Aggressive Sebaceous Gland Hyperplasia in a Young Girl With MSH2 Gene Mutation: A Rare Presentation.","authors":"Aniruddh Heroor, Vijitha S Vempuluru, Saumya Jakati, Swathi Kaliki","doi":"10.1097/IOP.0000000000002830","DOIUrl":"10.1097/IOP.0000000000002830","url":null,"abstract":"<p><p>Sebaceous gland hyperplasia is a benign cutaneous entity commonly seen in older men. Occasionally, it can develop in young patients on immunosuppression with cyclosporine or in adolescent boys in the peripubertal age group. It is extremely rare in young children with no reports of eyelid involvement. It is believed to have no systemic associations, unlike sebaceous adenoma, which is associated with Muir-Torre syndrome. Herein, the authors present a rare case of a young girl with recurrent and aggressive eyelid sebaceous hyperplasia who was treated by a wide local excision of the lesion. The histopathology showed intact nuclear expression of mismatch repair proteins MLH 1, MSH 2, MSH 6, and PMS 2, and the genetic testing revealed a missense mutation in the MSH2 gene.</p>","PeriodicalId":19588,"journal":{"name":"Ophthalmic Plastic and Reconstructive Surgery","volume":" ","pages":"e58-e59"},"PeriodicalIF":1.2,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142801694","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Iatrogenic Erosion of Orbital Walls due to Expanding Hydrogel Explant.","authors":"Terence Ang, Clare Quigley, James Slattery, Dinesh Selva","doi":"10.1097/IOP.0000000000002814","DOIUrl":"10.1097/IOP.0000000000002814","url":null,"abstract":"<p><p>Hydrogel scleral buckles are a hydrophilic explant that may lead to significant delayed complications. They can insidiously enlarge over decades and may mimic an orbital tumor or cyst. The authors report a case of an expansive hydrogel scleral explant in a previously eviscerated socket. A 58-year-old male presented with a 2-week history of severe pain in his left anophthalmic socket. And 31 years prior, he had sustained OS trauma and undergone a series of surgeries. Details of these procedures were unavailable; however, he had ultimately proceeded to globe evisceration. MRI revealed a large lobulated cyst-like orbital mass with internal calcification, which had expanded the left orbit with erosion of the medial wall, lateral wall, and roof. It extended to involve the ethmoid and frontal paranasal sinuses. He proceeded to a lateral orbitotomy, revealing the lesion to be an expanded hydrogel scleral buckle explant. Postoperatively, there was a significant improvement in his pain.</p>","PeriodicalId":19588,"journal":{"name":"Ophthalmic Plastic and Reconstructive Surgery","volume":" ","pages":"e45-e48"},"PeriodicalIF":1.2,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142801902","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Manuscript Reviewers 2024.","authors":"","doi":"10.1097/IOP.0000000000002930","DOIUrl":"https://doi.org/10.1097/IOP.0000000000002930","url":null,"abstract":"","PeriodicalId":19588,"journal":{"name":"Ophthalmic Plastic and Reconstructive Surgery","volume":"41 2","pages":"122-124"},"PeriodicalIF":1.2,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143557387","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Re: \"Peri-Levator Betamethasone Versus Triamcinolone Injection in Management of Thyroid Eye Disease-Related Upper Eyelid Retraction Without Proptosis\".","authors":"Ameena Jennifer Kamal Batcha, Pratheeba Devi Nivean, Nivean Madhivanan","doi":"10.1097/IOP.0000000000002918","DOIUrl":"https://doi.org/10.1097/IOP.0000000000002918","url":null,"abstract":"","PeriodicalId":19588,"journal":{"name":"Ophthalmic Plastic and Reconstructive Surgery","volume":"41 2","pages":"234"},"PeriodicalIF":1.2,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143557395","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Spontaneous Resolution of Traumatic Secondary Acquired Lacrimal Duct Obstruction.","authors":"Anannya Abhyankar Joshi, Mohammad Javed Ali","doi":"10.1097/IOP.0000000000002758","DOIUrl":"10.1097/IOP.0000000000002758","url":null,"abstract":"","PeriodicalId":19588,"journal":{"name":"Ophthalmic Plastic and Reconstructive Surgery","volume":"41 2","pages":"e75"},"PeriodicalIF":1.2,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143557410","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Polytherapy Intervention in an Experimental Traumatic Optic Neuropathy Mouse Model.","authors":"David T Tse, Hua Wang, Wensi Tao, Robert C O'Brien, Brian C Tse, Daniel Pelaez","doi":"10.1097/IOP.0000000000002917","DOIUrl":"https://doi.org/10.1097/IOP.0000000000002917","url":null,"abstract":"<p><strong>Purpose: </strong>To test a novel early polytherapy treatment strategy targeting mitochondrial bioenergetics, glutamate excitotoxicity, and sterile inflammatory response molecular pathways associated with retinal ganglion cell survival following optic nerve trauma.</p><p><strong>Methods: </strong>Twenty C57BL/6J mice were subjected to sonication-induced traumatic optic neuropathy injury. The control group (n = 10) received intravitreal, retrobulbar, and subcutaneous phosphate buffered saline injections on days 0 and 3 (no repeat retrobulbar vehicle). On day 0, the treatment group (n = 10) received injections of intravitreal interleukin-1 receptor antagonist with ketamine, retrobulbar ropivacaine, and subcutaneous etanercept. Treatment group animals had 1% (wt/vol) N-acetylcysteine ad libitum supplemented in drinking water from day 1. On day 3, intravitreal pan-ephrin receptor antagonist peptide and subcutaneous elamipretide and etanercept injections were given. Pattern electroretinogram assessments continued at weeks 0, 1, 2, 4, 6, 8, 10, and 12. Optical coherence tomography retinal layer thickness was measured on naive, control, and treatment groups at week 12. The whole mount retinas were harvested for retinal ganglion cell quantitation.</p><p><strong>Results: </strong>At 12 weeks, the averaged retinal ganglion cell density count in the control group was lower (413.37 ± 41.77 cells/mm2) compared with treatment (553.97 ± 18.00 cells/mm2; p < 0.001) and naive (595.94 ± 30.67cells/mm2; p < 0.001) groups. Ganglion cell complex layer thicknesses showed control group (49.29 ± 5.48 μm) thinner than the treated (61.00 ± 2.57 μm; p = 0.004) and naive (67.00 ± 6.12 μm; p = 0.004) groups. No significant difference was seen at 12 weeks between the treated and naive groups. Pattern electroretinogram recordings in the control group revealed a statistically significant decrease in amplitudes for all time points. Apart from week 8, the amplitudes in the treatment group did not significantly differ from the baseline at any time point.</p><p><strong>Conclusions: </strong>Early combinatorial therapeutic intervention to address disparate molecular pathways following optic nerve trauma effectively halts retinal neurons' progressive structural and functional degeneration.</p>","PeriodicalId":19588,"journal":{"name":"Ophthalmic Plastic and Reconstructive Surgery","volume":" ","pages":""},"PeriodicalIF":1.2,"publicationDate":"2025-02-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143409528","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Inoperable Orbital Epithelioid Hemangioendothelioma Treated With Radiation Therapy.","authors":"Naomi E Gutkind, Sugi Panneerselvam, Lauren C Kiryakoza, Marissa K Shoji, Ying Chen, Rayan Abou-Kzam, Vincent Tang, Sander Dubovy, Wendy Lee","doi":"10.1097/IOP.0000000000002908","DOIUrl":"https://doi.org/10.1097/IOP.0000000000002908","url":null,"abstract":"<p><p>Epithelioid hemangioendotheliomas (EHs) are rare vascular tumors originating from bone or soft tissue. An 81-year-old woman with inoperable EH of the right orbit presented with right-sided decreased vision, proptosis, and facial numbness secondary to a frontotemporal soft tissue mass. Imaging revealed a heterogeneous enhancing mass surrounding the right sphenoid bone extending into the right orbit and right temporal intracranial fossa. The biopsy of the lesion was consistent with EH. The patient received orbital radiation with improvement in her proptosis, vision, and tumor size. However, 20 months later, she developed metastatic spread and her brief improvement rapidly worsened to require eventual enucleation. Orbital EH is rare, with few case reports in the literature. Treatment typically involves complete excision, although adjuvant radiation has been rarely reported. This case highlights rare orbital EH treated initially with radiotherapy with good effect, potentially indicating a role for this palliative therapy in extensive disease.</p>","PeriodicalId":19588,"journal":{"name":"Ophthalmic Plastic and Reconstructive Surgery","volume":" ","pages":""},"PeriodicalIF":1.2,"publicationDate":"2025-02-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143409765","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effectiveness of Minimally Invasive Partial Orbicularis Myectomy for Treating Benign Essential Blepharospasm: A Study Using the Jankovic Scale and Blepharospasm Disability Index.","authors":"Semih Doğan, İbrahim Edhem Yilmaz, Şeyhmus Ari","doi":"10.1097/IOP.0000000000002914","DOIUrl":"https://doi.org/10.1097/IOP.0000000000002914","url":null,"abstract":"<p><strong>Purpose: </strong>This study aimed to evaluate the effectiveness of minimally invasive partial orbicularis myectomy in treating benign essential blepharospasm while assessing the utility of the Jankovic Rating Scale and Blepharospasm Disability Index as comprehensive outcome measures.</p><p><strong>Methods: </strong>A retrospective study was conducted on 18 patients (36 eyes) with benign essential blepharospasm who underwent partial orbicularis myectomy between 2018 and 2022. All patients had previously shown inadequate response to botulinum toxin injections. Jankovic Rating Scale and Blepharospasm Disability Index scores were assessed preoperatively and at 1, 3, 6, and 12 months postoperatively to capture both symptom severity and functional impact. Statistical analysis was performed using the Wilcoxon signed-rank test.</p><p><strong>Results: </strong>The median preoperative Jankovic Rating Scale score of 7.5 decreased to 3 one year postoperatively, reflecting a 50% improvement in symptom severity. Concurrently, the median Blepharospasm Disability Index score reduced from 20 to 9.5, indicating a 47.22% enhancement in functional capacity at 1 year. Both reductions were statistically significant (p < 0.001) and sustained throughout the 1-year follow-up period. No significant complications were reported.</p><p><strong>Conclusion: </strong>Minimally invasive partial orbicularis myectomy demonstrates significant and sustained improvement in both symptom severity and functional disability in patients with benign essential blepharospasm refractory to botulinum toxin treatment. The combined application of Jankovic Rating Scale and Blepharospasm Disability Index proves to be an effective approach in evaluating surgical outcomes, offering valuable insights into both the clinical efficacy of partial orbicularis myectomy and its impact on patients' daily functioning.</p>","PeriodicalId":19588,"journal":{"name":"Ophthalmic Plastic and Reconstructive Surgery","volume":" ","pages":""},"PeriodicalIF":1.2,"publicationDate":"2025-02-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143409667","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}