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The Many NICU Shades of Gray: Understanding and Navigating Uncertainty in Clinical Care. 许多NICU灰色阴影：理解和导航临床护理的不确定性。
NeoReviews Pub Date : 2026-02-01 DOI: 10.1542/neo.27-2-098
Erin Rholl, Sahra Cahoon, Jessica T Fry, Amy Schlegel, Mary Angela Woodward, Sanjana Adig, Zeynep N I Salih
{"title":"The Many NICU Shades of Gray: Understanding and Navigating Uncertainty in Clinical Care.","authors":"Erin Rholl, Sahra Cahoon, Jessica T Fry, Amy Schlegel, Mary Angela Woodward, Sanjana Adig, Zeynep N I Salih","doi":"10.1542/neo.27-2-098","DOIUrl":"10.1542/neo.27-2-098","url":null,"abstract":"<p><p>Uncertainty exists within many aspects of neonatal care. However, neonatal intensive care unit clinicians report varying comfort levels with managing uncertainty in clinical care. Although accepting ambiguity and demonstrating proficiency in communication are required components of medical education, there is a lack of formal curricula on uncertainty in medicine. Despite this, clinicians must find ways to effectively partner with parents to develop care plans in situations with elements of uncertainty. This article reviews frameworks of uncertainty, perspectives, and experiences of parents and neonatologists; examines approaches to navigating uncertainty in clinical care; and suggests the need for formal training to manage uncertainty in neonatology.</p>","PeriodicalId":19465,"journal":{"name":"NeoReviews","volume":"27 2","pages":"e84-e93"},"PeriodicalIF":0.0,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146097349","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Ethics Education in Neonatology: Integrating Theory, Multimodal Methods, and AI Innovation. 新生儿伦理学教育：整合理论、多模式方法与人工智能创新。
NeoReviews Pub Date : 2026-02-01 DOI: 10.1542/neo.27-2-099
Anne Sullivan, Gina Geis, Christy Cummings
{"title":"Ethics Education in Neonatology: Integrating Theory, Multimodal Methods, and AI Innovation.","authors":"Anne Sullivan, Gina Geis, Christy Cummings","doi":"10.1542/neo.27-2-099","DOIUrl":"10.1542/neo.27-2-099","url":null,"abstract":"<p><p>This review examines current approaches to ethics education in neonatal-perinatal medicine (NPM), integrating adult learning theory, diverse teaching modalities, and emerging technologies to enhance training for neonatal clinicians. Foundational strategies include case-based discussions, simulation, interprofessional learning, and structured debriefing, which promote critical reflection, moral reasoning, and shared decision-making skills. Assessment of ethics education is challenging given the interplay of cognitive, emotional, and interpersonal domains. Tools such as knowledge tests, milestone-based competency frameworks, performance-based assessments, and structured feedback checklists offer complementary methods for evaluating knowledge, skills, and attitudes. Innovations in ethics education increasingly leverage artificial intelligence (AI), including generative AI for case creation, conversational agents for virtual role-play, and interactive simulations. These tools can expand access, foster individualized learning, and model complex ethical scenarios, but require safeguards against bias, misinformation, and oversimplification. A structured, theory-informed ethics curriculum, integrated with robust assessment strategies and mindful AI applications, can strengthen ethical competence across the learning continuum and better equip clinicians to navigate moral distress, honor parental values, address equity concerns, and support family-centered decision-making.</p>","PeriodicalId":19465,"journal":{"name":"NeoReviews","volume":"27 2","pages":"e73-e83"},"PeriodicalIF":0.0,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146097270","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Persistent Bradycardia and Hypoperfusion in an Infant Despite Neonatal Resuscitation. 新生儿复苏后持续性心动过缓和灌注不足一例。
NeoReviews Pub Date : 2026-02-01 DOI: 10.1542/neo.27-2-095
Alexis Etheridge, Aishwarrya Jayapal, Robert Angert
{"title":"Persistent Bradycardia and Hypoperfusion in an Infant Despite Neonatal Resuscitation.","authors":"Alexis Etheridge, Aishwarrya Jayapal, Robert Angert","doi":"10.1542/neo.27-2-095","DOIUrl":"https://doi.org/10.1542/neo.27-2-095","url":null,"abstract":"","PeriodicalId":19465,"journal":{"name":"NeoReviews","volume":"27 2","pages":"e106-e110"},"PeriodicalIF":0.0,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146097333","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Recognizing Communication as a Procedural Skill in Neonatology. 认识到沟通是新生儿科的一项程序性技能。
NeoReviews Pub Date : 2026-02-01 DOI: 10.1542/neo.27-2-097
Shannon Y Adams, Natalia Henner, Shayna D Hibbs, Stephanie Marshall, Jessica T Fry
{"title":"Recognizing Communication as a Procedural Skill in Neonatology.","authors":"Shannon Y Adams, Natalia Henner, Shayna D Hibbs, Stephanie Marshall, Jessica T Fry","doi":"10.1542/neo.27-2-097","DOIUrl":"10.1542/neo.27-2-097","url":null,"abstract":"<p><p>Many of the ethical challenges that arise in the neonatal intensive care unit (NICU) stem from communication difficulties between families and clinicians. Parents in the NICU face tremendous stress, including separation from their infants, uncertainty about clinical outcomes, and fear for the future; they require clear and compassionate communication from clinicians to build trust and engage in shared decision-making. In this review, we explore how trauma that parents experience in the NICU shapes their communication needs, examine the role of communication in providing trauma-informed care, describe competencies in communication for neonatal clinicians, and depict established and novel models of communication training. We propose that communication should be thought of as a core clinical skill for neonatologists, and similar to procedural skills, requires dedicated training and practice to improve.</p>","PeriodicalId":19465,"journal":{"name":"NeoReviews","volume":"27 2","pages":"e94-e102"},"PeriodicalIF":0.0,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146097328","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cystic Encephalomalacia in a Neonate With a Rash. 新生儿伴皮疹的囊性脑软化症。
NeoReviews Pub Date : 2026-02-01 DOI: 10.1542/neo.27-2-094
Elizabeth Onishchenko, Christina Zhou, Tulsi Patel, Walid Hussain
{"title":"Cystic Encephalomalacia in a Neonate With a Rash.","authors":"Elizabeth Onishchenko, Christina Zhou, Tulsi Patel, Walid Hussain","doi":"10.1542/neo.27-2-094","DOIUrl":"https://doi.org/10.1542/neo.27-2-094","url":null,"abstract":"","PeriodicalId":19465,"journal":{"name":"NeoReviews","volume":"27 2","pages":"e111-e115"},"PeriodicalIF":0.0,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146097284","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Trauma-Informed Care in the Neonatal Intensive Care Unit: Infants, Families, and Care Teams. 新生儿重症监护病房的创伤知情护理：婴儿、家庭和护理团队。
NeoReviews Pub Date : 2026-02-01 DOI: 10.1542/neo.27-2-100
Catherine M Groden
{"title":"Trauma-Informed Care in the Neonatal Intensive Care Unit: Infants, Families, and Care Teams.","authors":"Catherine M Groden","doi":"10.1542/neo.27-2-100","DOIUrl":"10.1542/neo.27-2-100","url":null,"abstract":"<p><p>In the neonatal intensive care unit (NICU), patients, families, and care teams are all likely to undergo traumatic experiences. Infants are separated from their parents and undergo multiple painful or stressful procedures. Families experience fear for their infants' health and survival and the disempowerment coming with a loss of parental role; many also experience differential treatment by race, language, or other factors. Care teams bear witness to the illness and sometimes death of infants and the pain of their families. All these and many other experiences constitute trauma, which may impact the long-term course of infants and families. Trauma-informed care has therefore been promoted as a universal practice. In the NICU, trauma-informed care principles may be applied to help optimally care for infants and their families as well as to support members of the care team.</p>","PeriodicalId":19465,"journal":{"name":"NeoReviews","volume":"27 2","pages":"e62-e72"},"PeriodicalIF":0.0,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146097396","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Neurodevelopmental Follow-Up of a Child With Congenital Cytomegalovirus Infection. 先天性巨细胞病毒感染儿童的神经发育随访。
NeoReviews Pub Date : 2026-01-01 DOI: 10.1542/neo.27-1-092
Roshani Gowda, Lori Burton, Vann Chau, Linh G Ly, Mehmet N Cizmeci
{"title":"Neurodevelopmental Follow-Up of a Child With Congenital Cytomegalovirus Infection.","authors":"Roshani Gowda, Lori Burton, Vann Chau, Linh G Ly, Mehmet N Cizmeci","doi":"10.1542/neo.27-1-092","DOIUrl":"https://doi.org/10.1542/neo.27-1-092","url":null,"abstract":"","PeriodicalId":19465,"journal":{"name":"NeoReviews","volume":"27 1","pages":"e54-e61"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145878720","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Improving Platelet Transfusion Practice. 改进血小板输注做法。
NeoReviews Pub Date : 2026-01-01 DOI: 10.1542/neo.27-1-085
Robert D Christensen, Patricia Davenport, Martha C Sola-Visner, Jamie Archambault, Cassidy Delaney, Timothy M Bahr, James C Elliott, Sarah J Ilstrup, Robin K Ohls
{"title":"Improving Platelet Transfusion Practice.","authors":"Robert D Christensen, Patricia Davenport, Martha C Sola-Visner, Jamie Archambault, Cassidy Delaney, Timothy M Bahr, James C Elliott, Sarah J Ilstrup, Robin K Ohls","doi":"10.1542/neo.27-1-085","DOIUrl":"10.1542/neo.27-1-085","url":null,"abstract":"<p><p>Applying best neonatal transfusion practices through transfusion stewardship programs can achieve better patient outcomes. Platelets, the focus of the present report, are the second most frequently transfused blood product in the neonatal intensive care unit (after red blood cell transfusion). Like many therapies in this field, platelet transfusions are associated with risks as well as benefits. Ongoing preclinical and clinical research continues to better define these risks and add to our understanding of disease pathogenesis. Although, in some instances, neonatal platelet transfusions obtained from adult donors can be lifesaving, mounting evidence suggests that such transfusions confer a dose-dependent risk of major bleeding, bronchopulmonary dysplasia, adverse neurodevelopment, and death. This review is intended to assist clinicians who care for hospitalized neonates by (1) clarifying the associations between platelet transfusions and adverse infant outcomes, (2) increasing awareness of a subset of neonates who are at high risk for receiving multiple platelet transfusions, (3) applying evidence-based restrictive platelet transfusion practices to mitigate the risks of platelet transfusions, and (4) highlighting both existing and novel experimental methods for treating thrombocytopenic neonates.</p>","PeriodicalId":19465,"journal":{"name":"NeoReviews","volume":"27 1","pages":"e11-e24"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145878764","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Sudden Unexpected Infant Death and Safe Sleep Practices. 婴儿意外猝死和安全睡眠习惯。
NeoReviews Pub Date : 2026-01-01 DOI: 10.1542/neo.27-1-084
Aniekanabasi N Udoko, Nicolle Fernandez Dyess, Sunah S Hwang, Christina R Fisher
{"title":"Sudden Unexpected Infant Death and Safe Sleep Practices.","authors":"Aniekanabasi N Udoko, Nicolle Fernandez Dyess, Sunah S Hwang, Christina R Fisher","doi":"10.1542/neo.27-1-084","DOIUrl":"10.1542/neo.27-1-084","url":null,"abstract":"<p><p>Sudden unexpected infant death (SUID) is the primary cause of post-neonatal mortality. SUID disproportionately affects preterm infants and infants admitted to the neonatal intensive care unit (NICU). NICU providers are charged with ensuring the implementation of safe sleep practices and caregiver education while balancing other acute medical needs. The persistent lack of improvement in sleep-related infant deaths and the release of updated recommendations from the American Academy of Pediatrics (AAP) have reinvigorated institutional and public health efforts to reduce SUID. In this review, we will discuss the nomenclature, epidemiology (including racial and ethnic disparities in SUID), and pathophysiology of sleep-related infant deaths. Finally, we will review the updated AAP recommendations on safe sleep and early transition to safe sleep in the NICU.</p>","PeriodicalId":19465,"journal":{"name":"NeoReviews","volume":"27 1","pages":"e1-e10"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145878911","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cytomegalovirus Infection in Pregnancy: Neonatal Implications. 妊娠期巨细胞病毒感染：对新生儿的影响
NeoReviews Pub Date : 2026-01-01 DOI: 10.1542/neo.27-1-089
Shelby Andrus, Kisti Fuller, Kendra Gray
{"title":"Cytomegalovirus Infection in Pregnancy: Neonatal Implications.","authors":"Shelby Andrus, Kisti Fuller, Kendra Gray","doi":"10.1542/neo.27-1-089","DOIUrl":"https://doi.org/10.1542/neo.27-1-089","url":null,"abstract":"","PeriodicalId":19465,"journal":{"name":"NeoReviews","volume":"27 1","pages":"e46-e49"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145878719","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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