NeoReviewsPub Date : 2026-05-01DOI: 10.1542/neo.27-5-015
Yashaswini Kelagere, Susanna Pappas, Shakuntala N Chandra, Sabah Kalyoussef
{"title":"Multiple Well-Circumscribed Cutaneous Lesions in a 6-Day-Old Neonate Born Extremely Preterm.","authors":"Yashaswini Kelagere, Susanna Pappas, Shakuntala N Chandra, Sabah Kalyoussef","doi":"10.1542/neo.27-5-015","DOIUrl":"https://doi.org/10.1542/neo.27-5-015","url":null,"abstract":"","PeriodicalId":19465,"journal":{"name":"NeoReviews","volume":"27 5","pages":"e314-e317"},"PeriodicalIF":0.0,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147818354","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
NeoReviewsPub Date : 2026-05-01DOI: 10.1542/neo.27-5-010
Lacey Prater, Jennifer Hanford
{"title":"Psychosocial Impact of Parental Presence During Neonatal Resuscitation.","authors":"Lacey Prater, Jennifer Hanford","doi":"10.1542/neo.27-5-010","DOIUrl":"10.1542/neo.27-5-010","url":null,"abstract":"<p><p>There has been a recent shift toward allowing parents to remain during resuscitation of their newborn because studies have found that parents generally prefer to be present during this time. However, questions remain about the psychosocial impact of parental presence during resuscitation on both parents and health care professionals. This review summarizes the current literature on the impact of this practice and outlines best practices for its implementation.</p>","PeriodicalId":19465,"journal":{"name":"NeoReviews","volume":"27 5","pages":"e279-e286"},"PeriodicalIF":0.0,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147818378","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
NeoReviewsPub Date : 2026-04-01DOI: 10.1542/neo.27-4-006
Leah Treffeisen, Luke P Burns, Caitlin MacGregor
{"title":"Acute Fatty Liver of Pregnancy: Neonatal Implications.","authors":"Leah Treffeisen, Luke P Burns, Caitlin MacGregor","doi":"10.1542/neo.27-4-006","DOIUrl":"https://doi.org/10.1542/neo.27-4-006","url":null,"abstract":"","PeriodicalId":19465,"journal":{"name":"NeoReviews","volume":"27 4","pages":"e244-e248"},"PeriodicalIF":0.0,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147593787","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
NeoReviewsPub Date : 2026-04-01DOI: 10.1542/neo.27-4-002
Allie N Dayno, Julia Crowley, Vaneeta Bamba, Elizabeth J K Bhoj, Karuna Shekdar, Shana E McCormack
{"title":"Neonatal Hypopituitarism.","authors":"Allie N Dayno, Julia Crowley, Vaneeta Bamba, Elizabeth J K Bhoj, Karuna Shekdar, Shana E McCormack","doi":"10.1542/neo.27-4-002","DOIUrl":"10.1542/neo.27-4-002","url":null,"abstract":"<p><p>Neonatal hypopituitarism, a collection of conditions characterized by 1 or more pituitary hormone deficiencies, is associated with various phenotypes, each characterized by specific clinical, hormonal, radiographic, and, sometimes, genetic findings. Signs and symptoms of neonatal hypopituitarism include hypoglycemia, prolonged jaundice, microphallus, midline defects, and feeding difficulties. The initial evaluation of neonates at risk of multiple pituitary hormone deficiencies includes laboratory assessment of all hormone axes and brain magnetic resonance imaging for visualization of the pituitary. Pediatric endocrinologists should be consulted to guide interpretation of laboratory results and management. Prompt initiation of treatment is expected to improve overall clinical outcomes. In this review, we summarize the spectrum of phenotypes associated with neonatal hypopituitarism, the role of genetic testing, and the clinical presentation of hypopituitarism in infancy. We also describe the diagnostic approaches and management strategies for each abnormality of the pituitary axis in neonates.</p>","PeriodicalId":19465,"journal":{"name":"NeoReviews","volume":"27 4","pages":"e211-e221"},"PeriodicalIF":0.0,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147593750","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
NeoReviewsPub Date : 2026-04-01DOI: 10.1542/neo.27-4-005
R K Shwetabh, Anita Singh, Kirti M Naranje, Kausik Mandal
{"title":"Diagnostic Dilemma in a Case of Persistent Thrombocytopenia With Feed Intolerance.","authors":"R K Shwetabh, Anita Singh, Kirti M Naranje, Kausik Mandal","doi":"10.1542/neo.27-4-005","DOIUrl":"https://doi.org/10.1542/neo.27-4-005","url":null,"abstract":"","PeriodicalId":19465,"journal":{"name":"NeoReviews","volume":"27 4","pages":"e239-e243"},"PeriodicalIF":0.0,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147593775","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
NeoReviewsPub Date : 2026-04-01DOI: 10.1542/neo.27-4-001
Pamela P Hu, Peter J Tebben
{"title":"Phosphate Metabolism in Neonates: Critical Considerations in the Perinatal Period.","authors":"Pamela P Hu, Peter J Tebben","doi":"10.1542/neo.27-4-001","DOIUrl":"10.1542/neo.27-4-001","url":null,"abstract":"<p><p>In the perinatal period, phosphate metabolism undergoes rapid change. This transition invites potential disruptions to phosphate homeostasis that may be overlooked. The neonatal population, particularly those with low birth weight, is vulnerable to developing hypophosphatemia due to a host of factors, including shorter gestation and nutrition. Evaluating for phosphate abnormalities early and regularly is critical to mitigating downstream effects of inadequate phosphate supply. The common causes and approach to evaluation and management of hypophosphatemia will be discussed in this review.</p>","PeriodicalId":19465,"journal":{"name":"NeoReviews","volume":"27 4","pages":"e197-e210"},"PeriodicalIF":0.0,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147593698","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
NeoReviewsPub Date : 2026-04-01DOI: 10.1542/neo.27-4-008
Alaa Aman Felimban, Tíscar Cavallé-Garrido, Gabriel Altit
{"title":"Evaluating Fetal Bradycardia on Prenatal Ultrasonography: A Review of Diagnostic Consideration and Clinical Implications.","authors":"Alaa Aman Felimban, Tíscar Cavallé-Garrido, Gabriel Altit","doi":"10.1542/neo.27-4-008","DOIUrl":"https://doi.org/10.1542/neo.27-4-008","url":null,"abstract":"","PeriodicalId":19465,"journal":{"name":"NeoReviews","volume":"27 4","pages":"e255-e262"},"PeriodicalIF":0.0,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147593695","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The Newborn With a Suspected Difference of Sex Development.","authors":"Frances Grimstad, Mélise Keays, Asher Schmedding, Riley Schmedding, Yee-Ming Chan","doi":"10.1542/neo.27-4-003","DOIUrl":"10.1542/neo.27-4-003","url":null,"abstract":"<p><p>The care of patients with difference(s) of sex development (DSD) is rapidly evolving, and this is especially true for the care of newborns with a suspected DSD. This review presents a paradigm for care, with an emphasis on a family-focused, shared decision-making approach that seeks to de-escalate the sense of \"social crisis\" that may arise when a baby is born with concern for a DSD. In addition to providing education and psychosocial support, tasks for the neonatal team include monitoring for hypoglycemia, determining the sex-chromosome complement, testing for congenital adrenal hyperplasia (and if appropriate, initiating treatment), and starting the diagnostic evaluation, recognizing that this evaluation and care will extend beyond the neonatal period and continue in the outpatient setting. Surgery is rarely indicated in the neonatal period, but parents may seek counseling about future surgical options; this counseling should avoid leading parents and families to believe that surgery can \"fix\" their child's DSD. A key component of care is connecting patients and families with clinicians who have the expertise to provide consultative and ongoing care-ideally a multidisciplinary team that includes mental-health, medical, and surgical expertise-and with written and online resources as well as support groups.</p>","PeriodicalId":19465,"journal":{"name":"NeoReviews","volume":"27 4","pages":"e222-e234"},"PeriodicalIF":0.0,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147593771","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}