Obesity Surgery最新文献

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Cardiac Abnormalities in Individuals Aged ≥ 50 Years with Severe Obesity Referred for Bariatric Surgery. 年龄≥ 50 岁的重度肥胖症患者转诊接受减肥手术时出现的心脏异常。
IF 2.9 3区 医学
Obesity Surgery Pub Date : 2024-09-01 Epub Date: 2024-08-01 DOI: 10.1007/s11695-024-07422-y
Michelle Lobeek, Aniek Peters, Sophie L van Veldhuisen, Yves G C J America, Michiel Rienstra, Eric J Hazebroek, Dirk J van Veldhuisen, Thomas M Gorter
{"title":"Cardiac Abnormalities in Individuals Aged ≥ 50 Years with Severe Obesity Referred for Bariatric Surgery.","authors":"Michelle Lobeek, Aniek Peters, Sophie L van Veldhuisen, Yves G C J America, Michiel Rienstra, Eric J Hazebroek, Dirk J van Veldhuisen, Thomas M Gorter","doi":"10.1007/s11695-024-07422-y","DOIUrl":"10.1007/s11695-024-07422-y","url":null,"abstract":"","PeriodicalId":19460,"journal":{"name":"Obesity Surgery","volume":null,"pages":null},"PeriodicalIF":2.9,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11349804/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141860489","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Effect of Maternal Bariatric Surgery on Offspring Anthropometry: A Mixed Cohort. 母亲减肥手术对后代人体测量的影响:混合队列
IF 2.9 3区 医学
Obesity Surgery Pub Date : 2024-09-01 Epub Date: 2024-06-14 DOI: 10.1007/s11695-024-07361-8
Raheleh Moradi, Maryam Navaee, Negar Zamaninour, Amin Setaredan, Abdolreza Pazouki, Ali Kabir
{"title":"The Effect of Maternal Bariatric Surgery on Offspring Anthropometry: A Mixed Cohort.","authors":"Raheleh Moradi, Maryam Navaee, Negar Zamaninour, Amin Setaredan, Abdolreza Pazouki, Ali Kabir","doi":"10.1007/s11695-024-07361-8","DOIUrl":"10.1007/s11695-024-07361-8","url":null,"abstract":"<p><strong>Purpose: </strong>Although bariatric surgery is associated with a decrease in obesity complications, it may affect the children's growth by a maternal nutritional deficiency. This study was conducted to assess the effect of maternal bariatric surgery on offspring anthropometry.</p><p><strong>Materials and methods: </strong>In a mixed cohort, anthropometric status of children aged 5 years or less born to mothers with a history of bariatric surgery was compared with a control group consists of peers born to mothers with obesity but without bariatric surgery. Anthropometric indices including crude and quantile values for BMI, weight, height, and head circumference at birth and the first 5 years of life were measured. Then, the adjusted effect of maternal surgical history on anthropometric status was estimated by linear regression.</p><p><strong>Results: </strong>From a total of 56 children, 28 born to mothers with a history of bariatric surgery, and 28 born to mothers with obesity but without bariatric surgery. At birth, weight (2915 vs 3225 g) and BMI (11.72 vs 12.94 kg/m<sup>2</sup>) were lower in the group with maternal bariatric surgery than in the control group (P = 0.02 and P = 0.03, respectively), although after regression adjustment, there was only a significant difference between the two groups in height for age value in children less than 5 years old (B = 0.872, P-value = 0.001).</p><p><strong>Conclusion: </strong>Bariatric surgery with decrease of weight indices at birth has a probable influence on growth and development in next years. Therefore, it is recommended further studies to identify unknown effect of types of preconception surgical procedures on childhood outcomes.</p>","PeriodicalId":19460,"journal":{"name":"Obesity Surgery","volume":null,"pages":null},"PeriodicalIF":2.9,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141321326","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Assessment of Metabolic and Bariatric Surgery Safety in Patients with Advanced Liver Fibrosis. 评估晚期肝纤维化患者代谢和减肥手术的安全性。
IF 2.9 3区 医学
Obesity Surgery Pub Date : 2024-09-01 Epub Date: 2024-07-30 DOI: 10.1007/s11695-024-07434-8
Giovani Barum, Leonardo Arenhart Paladini, Pedro G Stevanato de Oliveira, Thais Rodrigues Moreira, Cristiane Valle Tovo, Ângelo Z Mattos
{"title":"Assessment of Metabolic and Bariatric Surgery Safety in Patients with Advanced Liver Fibrosis.","authors":"Giovani Barum, Leonardo Arenhart Paladini, Pedro G Stevanato de Oliveira, Thais Rodrigues Moreira, Cristiane Valle Tovo, Ângelo Z Mattos","doi":"10.1007/s11695-024-07434-8","DOIUrl":"10.1007/s11695-024-07434-8","url":null,"abstract":"<p><strong>Purpose: </strong>The well-established relationship between obesity and metabolic dysfunction-associated steatotic liver disease (MASLD) is a key etiological factor in the development of liver cirrhosis. Bariatric surgery is an effective treatment for weight loss in patients with moderate-to-severe obesity, also playing a role in controlling MASLD. However, surgical safety in patients with advanced fibrosis remains to be established. This study aimed to evaluate the safety and repercussions of bariatric surgery according to fibrosis stage.</p><p><strong>Materials and methods: </strong>Patients undergoing bariatric surgery who had an intraoperative liver biopsy were retrospectively evaluated. Preoperative and postoperative data were collected from medical records, and results were stratified according to fibrosis stage into early fibrosis (no fibrosis or stages 1 and 2) and advanced fibrosis (stages 3 and 4).</p><p><strong>Results: </strong>The study included 1185 patients: 1129 with early fibrosis and 56 with advanced fibrosis. The advanced fibrosis group had higher percentage of men (35.7% vs 21.6%, p = 0.014) and of people with diabetes (42.9% vs 16.5%, p < 0.001) and hypertension (57.1% vs 41.4%, p = 0.012). Patients with advanced fibrosis also required longer hospitalizations (4.64 vs 4.06 days, p < 0.001) and were more frequently admitted to the intensive care unit (7.1% vs 2.9%, p = 0.038). The groups did not differ significantly in other outcomes. There were no deaths in either group.</p><p><strong>Conclusion: </strong>Bariatric surgery proved to be safe, with similar complication rates in patients with advanced fibrosis and in those with early fibrosis.</p>","PeriodicalId":19460,"journal":{"name":"Obesity Surgery","volume":null,"pages":null},"PeriodicalIF":2.9,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141792924","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Dissemination of the 2022 ASMBS and IFSO Guidelines for Bariatric Surgery: What Has Reached Primary Care Providers? 2022 年 ASMBS 和 IFSO 减肥手术指南的传播:初级保健提供者了解到了什么?
IF 2.9 3区 医学
Obesity Surgery Pub Date : 2024-09-01 Epub Date: 2024-08-15 DOI: 10.1007/s11695-024-07449-1
John Hulse, Richard Slay, Mary Kate Bryant, T Karl Byrne, Rana Pullatt
{"title":"Dissemination of the 2022 ASMBS and IFSO Guidelines for Bariatric Surgery: What Has Reached Primary Care Providers?","authors":"John Hulse, Richard Slay, Mary Kate Bryant, T Karl Byrne, Rana Pullatt","doi":"10.1007/s11695-024-07449-1","DOIUrl":"10.1007/s11695-024-07449-1","url":null,"abstract":"<p><strong>Background: </strong>Only 1% of Americans eligible for metabolic and bariatric surgery (MBS) receive MBS. Prior studies have analyzed primary care provider (PCP) referral patterns and perceptions of MBS as a potential barrier to increasing MBS. However, less data exists regarding PCP knowledge of MBS indications and outcomes. Following the 2022 update to the indications for MBS by the ASMBS and IFSO, the number of eligible patients is only expected to increase. We evaluated PCP knowledge regarding the existence of the 2022 ASMBS and IFSO updated guidelines, MBS indications, and MBS outcomes.</p><p><strong>Methods: </strong>An 11-question survey was emailed to primary care residents, advanced practice providers, and faculty at a single institution.</p><p><strong>Results: </strong>Of 151 surveys distributed, 39.7% responded (n = 60). 95% were unaware of the 2022 updated guidelines. On multiple choice questions, 16.3% correctly identified the average weight loss from MBS, and 46.8% correctly answered the diabetes remission rate following MBS. Trainee answers were not statistically significant from practicing PCPs. Fifteen respondents had referred a patient for MBS, but this subgroup did not perform significantly better on the assessment. A total of 72.3% of respondents reported inadequate MBS education during their training, and 85.1% were interested in additional education.</p><p><strong>Conclusions: </strong>We present the first assessment of PCP MBS knowledge since the release of the 2022 updated ASMBS and IFSO guidelines. This study indicates a gap in PCPs' knowledge regarding the updated guidelines and represents an opportunity for collaboration with our primary care colleagues to provide further MBS education.</p>","PeriodicalId":19460,"journal":{"name":"Obesity Surgery","volume":null,"pages":null},"PeriodicalIF":2.9,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11349814/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141982911","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Can You Believe It? How to Deal with an Intragastric Balloon Migration in the Pleural Cavity. 您相信吗?如何处理胸膜腔内胃内球囊移位。
IF 2.9 3区 医学
Obesity Surgery Pub Date : 2024-09-01 Epub Date: 2024-06-19 DOI: 10.1007/s11695-024-07365-4
Federico Marchesi, Giorgio Dalmonte, Matteo Riccò, Lucia Ballabeni, Francesco Tartamella, Simone Bosi, Marina Valente
{"title":"Can You Believe It? How to Deal with an Intragastric Balloon Migration in the Pleural Cavity.","authors":"Federico Marchesi, Giorgio Dalmonte, Matteo Riccò, Lucia Ballabeni, Francesco Tartamella, Simone Bosi, Marina Valente","doi":"10.1007/s11695-024-07365-4","DOIUrl":"10.1007/s11695-024-07365-4","url":null,"abstract":"","PeriodicalId":19460,"journal":{"name":"Obesity Surgery","volume":null,"pages":null},"PeriodicalIF":2.9,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141420039","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Metabolic and Bariatric Surgeon Criteria-An International Experts' Consensus. 代谢与减肥外科医生标准--国际专家共识。
IF 2.9 3区 医学
Obesity Surgery Pub Date : 2024-09-01 Epub Date: 2024-07-24 DOI: 10.1007/s11695-024-07395-y
Mohammad Kermansaravi, Sonja Chiappetta, Scott A Shikora, Mario Musella, Lilian Kow, Edo Aarts, Syed Imran Abbas, Ahmad Aly, Ali Aminian, Luigi Angrisani, Syed Tanseer Asghar, Ahmad Bashir, Estuardo Behrens, Helmuth Billy, Camilo Boza, Wendy A Brown, Daniel Oscar Caina, Miguel A Carbajo, Jean-Marc Chevallier, Benjamin Clapp, Ricardo V Cohen, Amir Hossein Davarpanah Jazi, Maurizio De Luca, Bruno Dilemans, Martin Fried, Michel Gagner, Manoel Galvao Neto, Pierre Y Garneau, Khaled Gawdat, Omar M Ghanem, Mohammed Al Hadad, Ashraf Haddad, Mohamad Hayssam ElFawal, Miguel F Herrera, Kelvin Higa, Jaques Himpens, Farah Husain, Kazunori Kasama, Radwan Kassir, Mousa Khoursheed, Haris Khwaja, Jon A Kristinsson, Matthew Kroh, Marina S Kurian, Muffazal Lakdawala, Teresa LaMasters, Wei-Jei Lee, Brijesh Madhok, Kamal Mahawar, Tarek Mahdy, Hazem Almomani, John Melissas, Karl Miller, Alexander Neimark, Taryel Omarov, Mariano Palermo, Pavlos K Papasavas, Chetan Parmar, Abdolreza Pazouki, Ralph Peterli, Tadeja Pintar, Luis Poggi, Jaime Ponce, Arun Prasad, Janey S A Pratt, Almino C Ramos, Masoud Rezvani, Karl Rheinwalt, Rui Ribeiro, Elena Ruiz-Ucar, Karim Sabry, Bassem Safadi, Asim Shabbir, Shahab ShahabiShahmiri, Erik Stenberg, Michel Suter, Safwan Taha, Halit Eren Taskin, Antonio Torres, Sergio Verboonen, Ramon Vilallonga, Kelvin Voon, Ala Wafa, Cunchuan Wang, Rudolf Weiner, Wah Yang, Natan Zundel, Gerhard Prager, Abdelrahman Nimeri
{"title":"Metabolic and Bariatric Surgeon Criteria-An International Experts' Consensus.","authors":"Mohammad Kermansaravi, Sonja Chiappetta, Scott A Shikora, Mario Musella, Lilian Kow, Edo Aarts, Syed Imran Abbas, Ahmad Aly, Ali Aminian, Luigi Angrisani, Syed Tanseer Asghar, Ahmad Bashir, Estuardo Behrens, Helmuth Billy, Camilo Boza, Wendy A Brown, Daniel Oscar Caina, Miguel A Carbajo, Jean-Marc Chevallier, Benjamin Clapp, Ricardo V Cohen, Amir Hossein Davarpanah Jazi, Maurizio De Luca, Bruno Dilemans, Martin Fried, Michel Gagner, Manoel Galvao Neto, Pierre Y Garneau, Khaled Gawdat, Omar M Ghanem, Mohammed Al Hadad, Ashraf Haddad, Mohamad Hayssam ElFawal, Miguel F Herrera, Kelvin Higa, Jaques Himpens, Farah Husain, Kazunori Kasama, Radwan Kassir, Mousa Khoursheed, Haris Khwaja, Jon A Kristinsson, Matthew Kroh, Marina S Kurian, Muffazal Lakdawala, Teresa LaMasters, Wei-Jei Lee, Brijesh Madhok, Kamal Mahawar, Tarek Mahdy, Hazem Almomani, John Melissas, Karl Miller, Alexander Neimark, Taryel Omarov, Mariano Palermo, Pavlos K Papasavas, Chetan Parmar, Abdolreza Pazouki, Ralph Peterli, Tadeja Pintar, Luis Poggi, Jaime Ponce, Arun Prasad, Janey S A Pratt, Almino C Ramos, Masoud Rezvani, Karl Rheinwalt, Rui Ribeiro, Elena Ruiz-Ucar, Karim Sabry, Bassem Safadi, Asim Shabbir, Shahab ShahabiShahmiri, Erik Stenberg, Michel Suter, Safwan Taha, Halit Eren Taskin, Antonio Torres, Sergio Verboonen, Ramon Vilallonga, Kelvin Voon, Ala Wafa, Cunchuan Wang, Rudolf Weiner, Wah Yang, Natan Zundel, Gerhard Prager, Abdelrahman Nimeri","doi":"10.1007/s11695-024-07395-y","DOIUrl":"10.1007/s11695-024-07395-y","url":null,"abstract":"<p><strong>Purpose: </strong>With the global epidemic of obesity, the importance of metabolic and bariatric surgery (MBS) is greater than ever before. Performing these surgeries requires academic training and the completion of a dedicated fellowship training program. This study aimed to develop guidelines based on expert consensus using a modified Delphi method to create the criteria for metabolic and bariatric surgeons that must be mastered before obtaining privileges to perform MBS.</p><p><strong>Methods: </strong>Eighty-nine recognized MBS surgeons from 42 countries participated in the Modified Delphi consensus to vote on 30 statements in two rounds. An agreement/disagreement among ≥ 70.0% of the experts was regarded to indicate a consensus.</p><p><strong>Results: </strong>Consensus was reached on 29 out of 30 statements. Most experts agreed that before getting privileges to perform MBS, surgeons must hold a general surgery degree and complete or have completed a dedicated fellowship training program. The experts agreed that the learning curves for the various operative procedures are approximately 25-50 operations for the LSG, 50-75 for the OAGB, and 75-100 for the RYGB. 93.1% of experts agreed that MBS surgeons should diligently record patients' data in their National or Global database.</p><p><strong>Conclusion: </strong>MBS surgeons should have a degree in general surgery and have been enrolled in a dedicated fellowship training program with a structured curriculum. The learning curve of MBS procedures is procedure dependent. MBS surgeons must demonstrate proficiency in managing postoperative complications, collaborate within a multidisciplinary team, commit to a minimum 2-year patient follow-up, and actively engage in national and international MBS societies.</p>","PeriodicalId":19460,"journal":{"name":"Obesity Surgery","volume":null,"pages":null},"PeriodicalIF":2.9,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141752266","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Response to: Comments on The Impact of Aprepitant on Nausea and Vomiting Following Laparoscopic Sleeve Gastrectomy: A Blinded Randomized Controlled Trial. 回应关于阿瑞匹坦对腹腔镜袖带胃切除术后恶心和呕吐的影响的评论:盲法随机对照试验。
IF 2.9 3区 医学
Obesity Surgery Pub Date : 2024-09-01 Epub Date: 2024-07-24 DOI: 10.1007/s11695-024-07404-0
Manuel A Guerrero, Elías Ortiz, Alberto I González, Valeria Jaime, José A Guzmán, Isaac Esparza, José O Orozco, Almino Ramos, Carlos Zerrweck
{"title":"Response to: Comments on The Impact of Aprepitant on Nausea and Vomiting Following Laparoscopic Sleeve Gastrectomy: A Blinded Randomized Controlled Trial.","authors":"Manuel A Guerrero, Elías Ortiz, Alberto I González, Valeria Jaime, José A Guzmán, Isaac Esparza, José O Orozco, Almino Ramos, Carlos Zerrweck","doi":"10.1007/s11695-024-07404-0","DOIUrl":"10.1007/s11695-024-07404-0","url":null,"abstract":"","PeriodicalId":19460,"journal":{"name":"Obesity Surgery","volume":null,"pages":null},"PeriodicalIF":2.9,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141752268","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Study of Omentum Reduction on the Improvement of Nausea and vomiting and Gastroesophageal Reflux Symptoms After Laparoscopic Gastric Sleeve Resection. 减少网膜对改善腹腔镜胃袖状切除术后恶心呕吐和胃食管反流症状的研究
IF 2.9 3区 医学
Obesity Surgery Pub Date : 2024-09-01 Epub Date: 2024-08-05 DOI: 10.1007/s11695-024-07423-x
Luansheng Liang, Xiangwen Zhao, Rong Gu, Ruibin Zheng, Yi Sun, Huiying Yang, Xia Zhou, Liping Fu
{"title":"A Study of Omentum Reduction on the Improvement of Nausea and vomiting and Gastroesophageal Reflux Symptoms After Laparoscopic Gastric Sleeve Resection.","authors":"Luansheng Liang, Xiangwen Zhao, Rong Gu, Ruibin Zheng, Yi Sun, Huiying Yang, Xia Zhou, Liping Fu","doi":"10.1007/s11695-024-07423-x","DOIUrl":"10.1007/s11695-024-07423-x","url":null,"abstract":"<p><strong>Objective: </strong>To investigate the effect of omentum reduction in laparoscopic sleeve gastrectomy (LSG) on the improvement of postoperative nausea and vomiting and gastroesophageal reflux symptoms.</p><p><strong>Methods: </strong>A retrospective study was performed on the case data of 198 obese patients who underwent LSG in the Department of Obesity and Metabolic Diseases of Xiaolan People's Hospital of Zhongshan from March 2021 to March 2022 and were divided into omentum reduction group and control group, with 99 cases in each group, and the preoperative body mass index (BMI) of the patients was recorded. Age, gender, comorbidities, and comparative analysis of operation time, blood loss, length of hospital stay, postoperative nausea and vomiting score, gastroesophageal reflux GerdQ score, postoperative pain score, weight, and postoperative complications were analyzed.</p><p><strong>Results: </strong>There were no significant differences in preoperative BMI, age, gender and comorbidities between the two groups (P > 0.05), but there were significant differences in intraoperative blood loss and operation time (P < 0.05). There were differences in postoperative nausea and vomiting scores and VAS pain scores between the two groups (P < 0.05). The GerdQ scores of the omental reduction group were 8.11 ± 2.84 points at 1 year, and those in the control group were 7.56 ± 2.67 points, which were 3.97 ± 4.09 points higher than those in the preoperative omentum reduction group and 3.42 ± 3.41 in the control group, with no significant difference (P > 0.05). There was no significant difference in the postoperative excess weight loss rate %EWL and postoperative complications (p > 0.05).</p><p><strong>Conclusion: </strong>Omentum reduction can improve short-term nausea and vomiting after LSG, but it cannot significantly improve long-term reflux symptoms.</p>","PeriodicalId":19460,"journal":{"name":"Obesity Surgery","volume":null,"pages":null},"PeriodicalIF":2.9,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141894007","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Randomized Controlled Trial Based US Commercial Payor Cost-Effectiveness Analysis of Endoscopic Sleeve Gastroplasty Versus Lifestyle Modification Alone for Adults With Class I/II Obesity. 基于随机对照试验的美国商业支付方成本效益分析:针对 I/II 级肥胖症成人的内镜袖状胃成形术与单纯生活方式调整。
IF 2.9 3区 医学
Obesity Surgery Pub Date : 2024-09-01 Epub Date: 2024-08-07 DOI: 10.1007/s11695-024-07324-z
Reem Z Sharaiha, Erik B Wilson, Natan Zundel, Michael B Ujiki, Barham K Abu Dayyeh
{"title":"Randomized Controlled Trial Based US Commercial Payor Cost-Effectiveness Analysis of Endoscopic Sleeve Gastroplasty Versus Lifestyle Modification Alone for Adults With Class I/II Obesity.","authors":"Reem Z Sharaiha, Erik B Wilson, Natan Zundel, Michael B Ujiki, Barham K Abu Dayyeh","doi":"10.1007/s11695-024-07324-z","DOIUrl":"10.1007/s11695-024-07324-z","url":null,"abstract":"<p><strong>Purpose: </strong>Endoscopic sleeve gastroplasty (ESG) is a minimally invasive day procedure that the MERIT randomized controlled trial (RCT) has demonstrated to be an effective and safe method of weight loss versus lifestyle modification alone. We sought to evaluate the cost-effectiveness of ESG from the perspective of a US commercial payer in a cohort of adults with class II and class I obesity with diabetes based on this RCT.</p><p><strong>Materials: </strong>We used a Markov modelling approach with BMI group health states and an absorbing death state. Baseline characteristics, utilities, BMI group transition probabilities, and adverse events (AEs) were informed by patient-level data from the MERIT RCT. Mortality was estimated by applying BMI-specific hazard ratios to US general population mortality rates. We used BMI-based health state utilities to reflect the impact of obesity comorbidities and applied disutilities due to ESG AEs. Costs included intervention costs, AE costs, and BMI-based annual direct healthcare costs to account for costs associated with obesity comorbidities. A willingness-to-pay threshold of $100,000 per quality-adjusted life year (QALY) was assumed.</p><p><strong>Results: </strong>In our base-case analysis over a 5-year time horizon, ESG was cost-effective versus lifestyle modification alone with an incremental cost-effectiveness ratio of $23,432/QALY. ESG remained cost-effective in all sensitivity analyses we conducted and was dominant in analyses with longer time horizons.</p><p><strong>Conclusion: </strong>ESG is a cost-effective treatment option for people living with obesity and should be considered in commercial health plans as an additional treatment option for clinically eligible patients.</p>","PeriodicalId":19460,"journal":{"name":"Obesity Surgery","volume":null,"pages":null},"PeriodicalIF":2.9,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141897927","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Navigating the Predictive Landscape: DiaRem's Role in Unveiling Outcomes for Diabetes Remission following ESG. 在预测领域航行:DiaRem 在揭示 ESG 后糖尿病缓解结果中的作用。
IF 2.9 3区 医学
Obesity Surgery Pub Date : 2024-09-01 Epub Date: 2024-08-08 DOI: 10.1007/s11695-024-07408-w
Ali Lahooti, Anam Rizvi, Andrew Canakis, Cynthia Akagbosu, Kate E Johnson, Kamal Hassan, Ila Lahooti, Mohamed Abu-Hammour, Enad Dawod, Qais Dawod, Carolyn Newberry, Kartik Sampath, David Carr-Locke, SriHari Mahadev, Cheguevara Afaneh, Gregory Dakin, Sonal Kumar, Michele Yeung, Sarah Barenbaum, Beverly Tchang, Alpana P Shukla, Louis J Aronne, Reem Z Sharaiha
{"title":"Navigating the Predictive Landscape: DiaRem's Role in Unveiling Outcomes for Diabetes Remission following ESG.","authors":"Ali Lahooti, Anam Rizvi, Andrew Canakis, Cynthia Akagbosu, Kate E Johnson, Kamal Hassan, Ila Lahooti, Mohamed Abu-Hammour, Enad Dawod, Qais Dawod, Carolyn Newberry, Kartik Sampath, David Carr-Locke, SriHari Mahadev, Cheguevara Afaneh, Gregory Dakin, Sonal Kumar, Michele Yeung, Sarah Barenbaum, Beverly Tchang, Alpana P Shukla, Louis J Aronne, Reem Z Sharaiha","doi":"10.1007/s11695-024-07408-w","DOIUrl":"10.1007/s11695-024-07408-w","url":null,"abstract":"<p><strong>Purpose: </strong>Rising obesity and type 2 diabetes mellitus (T2DM) rates can be mitigated by various strategies, with a 10% total body weight loss (TBWL) threshold often required for T2DM remission. T2DM remission rates after bariatric surgery like Roux-en-Y gastric bypass (RYGB) are well established; endoscopic sleeve gastroplasty (ESG) is a less invasive option that averages 15% TBWL and allows for T2DM remission. This study explores the DiaRem (Diabetes Remission post-RYGB) score's ability to predict T2DM remission 1-year post-ESG.</p><p><strong>Materials and methods: </strong>We conducted a retrospective cohort study on 39 individuals with T2DM who underwent ESG. Age, utilization of diabetes medications, insulin administration, and hemoglobin A1c levels were used to calculate the DiaRem score. The area under the receiver operating characteristic curve (AUC) was employed to evaluate the discriminative ability of DiaRem in distinguishing diabetes remission.</p><p><strong>Results: </strong>Among the 39 patients with a median hemoglobin A1c of 6.7, 12.8% required insulin, and 43.6% used diabetes medication. At 1-year post-ESG, 69.2% of patients experienced diabetes remission with a median %TWBL of 12.7. The DiaRem score's ability to detect diabetes resolution for ESG patients had a sensitivity of 100% and a specificity of 58.3%, at the optimal cutoff value of 10. The AUC was 0.779 (95% CI 0.546-0.959).</p><p><strong>Conclusion: </strong>Our study demonstrated the DiaRem score's predictive value for T2DM remission post-ESG, highlighting its utility in clinical decision-making for ESG-related outcomes. Further investigation is needed to identify alternative indicators that may enhance predictive accuracy, thus refining personalized decision-making for this patient group.</p>","PeriodicalId":19460,"journal":{"name":"Obesity Surgery","volume":null,"pages":null},"PeriodicalIF":2.9,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141907295","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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