Nigerian Journal of Pure and Applied Sciences最新文献

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Antimicrobial, Phytochemical and Antioxidant Screening of Acalypha fimbriata Leaf Extract for Alternative Antimicrobial Therapy 黑桫椤叶提取物的抗菌、植物化学和抗氧化性筛选
Nigerian Journal of Pure and Applied Sciences Pub Date : 2023-05-04 DOI: 10.48198/njpas/22.b05
Okunye O.L., Idowu P.A., Okanlawon B.M., Adejumo O.E., Saka A.S., Oyinloye O.E., Ayedun J.S., Adeyemo O.M., Kaseem L.S., Idowu A.O.
{"title":"Antimicrobial, Phytochemical and Antioxidant Screening of Acalypha fimbriata Leaf Extract for Alternative Antimicrobial Therapy","authors":"Okunye O.L., Idowu P.A., Okanlawon B.M., Adejumo O.E., Saka A.S., Oyinloye O.E., Ayedun J.S., Adeyemo O.M., Kaseem L.S., Idowu A.O.","doi":"10.48198/njpas/22.b05","DOIUrl":"https://doi.org/10.48198/njpas/22.b05","url":null,"abstract":"In folklore, Acalypha fimbriata have been associated with ‘cure all’ properties, but without sufficient empirical ethno-pharmacological scientific backups. This research work is therefore necessitated to determine the antimicrobial, phytochemicals and antioxidant activity of Acalypha fimbriata. The leaf of Acalypha fimbriata were Soxhlet extracted, reconstituted, and screened for phytochemical constituent of antimicrobial importance. Conventional biochemical characterization was carried out on the isolates of Staphylococcus aureus, Escherichia coli Pseudomonas aeruginosa and Klebsiella pneumoniae obtained for the research work and the antimicrobial activity of the plant sample was determined using the agar well diffusion technique. The minimum inhibitory concentration (MIC), minimum bactericidal concentration (MBC) of the extract were determined by broth dilution method on the isolates. The antioxidant activity of the extract was determined using 2,2-diphenyl-1-picrylhydrazyl (DPPH) method and Graphpad prism were used to interprets the data. Alkaloids, flavonoid, anthraquinones, tannins and saponins was found in the leaf extract. Staphylococcus aureus exhibited highest zone of growth inhibition (28mm) at 100mg/ml while Pseudomonas aeruginosa had the lowest (14mm) at 100mg/ml from the antimicrobial assay. In the determination of the minimum inhibitory concentration and minimum bactericidal concentration, Staphylococcus aureus exhibited MIC and MBC at 0.625µg/ml and 12.5 µg/ml, while Pseudomonas aeruginosa elicited MIC and MBC at 10 µg/ml and >10 µg/ml of MIC and MBC respectively. Themethanol extract of the plant acted as hydrogen/electrons donor or scavenger of radicals with fifty percent inhibitory concentration (IC50) of 59.83 µg/ml while that of Ascorbic acid (standard) was found to be 92.70 µg/ml using. The varied MIC’s and MBC’s obtained coupled with the values recorded for the antioxidant radicals validate the antimicrobial and antioxidant potential of Acalypha fimbriata that can be explored for therapeutic option, if further purified and optimally processed.","PeriodicalId":194209,"journal":{"name":"Nigerian Journal of Pure and Applied Sciences","volume":"26 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"120962110","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Assessment of the Hepato-protective Effects of Combined Ethanolic Extract of Psidiumguajava and Carica papaya Leaves in Rats Challenged with Cadmium 番石榴和番木瓜叶乙醇提取物对镉中毒大鼠肝保护作用的评价
Nigerian Journal of Pure and Applied Sciences Pub Date : 2023-05-04 DOI: 10.48198/njpas/22.b14
Orororo, O. C., Udi, O. A.
{"title":"Assessment of the Hepato-protective Effects of Combined Ethanolic Extract of Psidium\u0000guajava and Carica papaya Leaves in Rats Challenged with Cadmium","authors":"Orororo, O. C., Udi, O. A.","doi":"10.48198/njpas/22.b14","DOIUrl":"https://doi.org/10.48198/njpas/22.b14","url":null,"abstract":"It has been shown that herbal extracts can protect intoxicated hepatocytes. Therefore, this study examined the hepato-protective effects of pooled ethanolic extract of Psidium guajava and Carica papaya leaves in rats challenged with Cadmium (Cd). Exactly 200g of the grounded leaves were soaked in ethanol for 48hours and was concentrated after filtration using a rotary evaporator. Fifteen adult female rats (150¬-±10g) were randomly assigned into three groups: Group 1 (control: received feed and water alone), Group 2 (Cd group; received single dose of Cd, 30mg/kg b wt, Group 3 (Cd + extract: received Cd as in group 2 and leaf extract 200mg/ kg bwt daily for 2 weeks). Rats were slaughtered and samples were taken for biochemical examination at the conclusion of the study period. When compared to controls, exposure to Cd alone resulted in a significant increase (p<0.05) in the activities of the alkaline phosphatase (ALP), aspartate aminotransferase (AST), alanine aminotransferase (ALT), and lactate dehydrogenase (LDH), as well as an increase in the level of total protein (TP). Hepatocytes exposed to cd underwent histological changes as well. As opposed to rats exposed to Cd alone, there was a significant decrease in the values of ALT, AST, ALP, LDH, and TP when Cd-challenged rats were given the combination ethanolic extract of P. guajava and C. papaya. The outcomes suggest that the biherbal combination of P. guajava and C. papaya can shield liver cells against Cd damage.","PeriodicalId":194209,"journal":{"name":"Nigerian Journal of Pure and Applied Sciences","volume":"59 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"117149646","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Pilot Study on the Prevalence of Transcription Factor 7-Like 2 Gene (TCFL2), Rs290487 in Ethnic Groups with Type 2 Diabetes Mellitus in Bayelsa State of Nigeria 转录因子7-样2基因(Transcription Factor 7-Like 2 Gene, TCFL2) Rs290487在尼日利亚巴耶尔萨州2型糖尿病人群中患病率的初步研究
Nigerian Journal of Pure and Applied Sciences Pub Date : 2023-05-04 DOI: 10.48198/njpas/22.b09
C.H. Madukosiri, O.O. Ezomoh, B.M. Amos-Tautua, Y.M. Tatfeng, D. Mishack, N. Akpeki, C.E. Echendu, S.P. Songca, E.T. Omu
{"title":"A Pilot Study on the Prevalence of Transcription Factor 7-Like 2 Gene (TCFL2), Rs290487 in Ethnic Groups with Type 2 Diabetes Mellitus in Bayelsa State of Nigeria","authors":"C.H. Madukosiri, O.O. Ezomoh, B.M. Amos-Tautua, Y.M. Tatfeng, D. Mishack, N. Akpeki, C.E. Echendu, S.P. Songca, E.T. Omu","doi":"10.48198/njpas/22.b09","DOIUrl":"https://doi.org/10.48198/njpas/22.b09","url":null,"abstract":"The negative impact of type 2 diabetes mellitus (T2DM) on individuals, families, health system and the economic development as a whole, is an important justification for research in this field. The present study is a hospital-based case-control type to ascertain the genetic susceptibility of T2DM among a sample population of various ethnic groups resident in Bayelsa State, Nigeria. Also evaluated was the relationship between transcription factor 7-like 2 (TCFL2) rs12255372 and rs290487 genetic polymorphisms with development of T2DM. Genotyping of TCFL2 rs12255372 and rs290487 were carried out using the polymerase chain reaction restriction fragment length polymorphism (PCR-RFLP) method. Among the indigenous groups, the allelic frequencies determined for the abnormal (CC) and the normal (TT) genotypes were 94.4 and 5.6 (%), respectively; whereas, the values 91.7 and 8.3 (%), in that other, were determined for the non-indigenous groups. A convincing significant difference was found between subjects with T2DMne and their counterpart controls within indigenous people of Bayelsa State with respect to confounders, including age (t=8.046, p<0.00001), BMI (t =2.628, p<0.0190), waist circumference (t=2.800, p=0.0091) and fasting blood sugar (t=3.212, p< 0.0006). This study verified the association of TCFL2 rs290487 with the development of T2DM in indigenous and non-indigenous people in Bayelsa State. The risk conferred by the homozygous CC genotype was higher than that of the heterozygous TC state – a fact indicative of an additive model of inheritance.","PeriodicalId":194209,"journal":{"name":"Nigerian Journal of Pure and Applied Sciences","volume":"11 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131106445","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Serum Biochemistry and Enzymatic Biomaker of Gercacinid Crabs from Mangrove Swamp of the Lagos Lagoon, Nigeria 尼日利亚拉各斯湖红树林沼泽Gercacinid蟹血清生化及酶促生物标志物研究
Nigerian Journal of Pure and Applied Sciences Pub Date : 2023-05-04 DOI: 10.48198/njpas/22.b19
R. Moruf, M. I. Abubakar, F. Abubakar
{"title":"Serum Biochemistry and Enzymatic Biomaker of Gercacinid Crabs from Mangrove Swamp of the Lagos Lagoon, Nigeria","authors":"R. Moruf, M. I. Abubakar, F. Abubakar","doi":"10.48198/njpas/22.b19","DOIUrl":"https://doi.org/10.48198/njpas/22.b19","url":null,"abstract":"Environmental factor is known to influence crab immune chemistry. This study presents the haemato-biochemical parameters and enzymatic biomarker of gercacinid crabs (Cardisoma guanhumi and Cardisoma armatum) from mangrove swamp of the Lagos Lagoon using standard procedure. The haemocyte subpopulations were higher in C. guanhumi than the percentage obtained in C. armatum with no significant difference (P > 0.05). Significantly, higher range values of aspartate aminotransferase (12.03±0.35 µi-1), alanine aminotransferase (10.07±0.58 µi-1), alkaline phosphatase (89.94±3.38 µi-1), lactate dehydrogenase (124.86±0.70 µi-1) and urea (33.90±2.00 mg dL-1) were recorded in C. guanhumi. Examined samples of gercacinid crabs showed significant difference only in malondialdehyde (among the enzymatic biomarkers) with mean values of 6.32±0.05 Hmol/mg pro and 9.36±0.27 Hmol/mg pro for C. guhanhumi and C. armatum respectively. The haemato-biochemical parameters of the gercacinid from the studied location varied across species.","PeriodicalId":194209,"journal":{"name":"Nigerian Journal of Pure and Applied Sciences","volume":"4 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125154210","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
In-Vitro Antibacterial Assay of Annona muricata Hydroethanolic Extracts 番荔枝水乙醇提取物体外抑菌试验研究
Nigerian Journal of Pure and Applied Sciences Pub Date : 2023-05-04 DOI: 10.48198/njpas/22.b08
U. C. Kanife, A. M. Ebabhi, G.O. Ovioma
{"title":"In-Vitro Antibacterial Assay of Annona muricata Hydroethanolic Extracts","authors":"U. C. Kanife, A. M. Ebabhi, G.O. Ovioma","doi":"10.48198/njpas/22.b08","DOIUrl":"https://doi.org/10.48198/njpas/22.b08","url":null,"abstract":"Annona muricata (Soursop) plant is well known to be therapeutic due to its phytochemical constituents. The antibacterial outcome of the hydro-ethanolic extracts of Annona muricata leaves, root and stem bark were evaluated on standard strains of Staphylococcus aureus (ATCC 29213), Escherichia coli (ATCC 29522), Pseudomonas aeruginosa (ATCC 27853) and Enterococcus faecalis (ATCC 29212) using agar well diffusion method. The extracts inhibited the growth of Staphylococcus aureus, Escherichia coli, Enterococcus faecalis at varied concentrations. The root extract at 25.88±0.22 mm on E. coli was observed to have the highest zone of inhibition while the leaves extract at 11.67±6.01 mm on E. coli revealed the least zone of inhibition. The quantitative and qualitative phytochemical assay of the leaves, stem bark and root affirmed the presence of tannins, saponins, alkaloids, flavonoids, and carbohydrate in varying percentages. The highest quantity of flavonoids and saponin were observed in the stem bark respectively at 15.57 % and 131.49 % while the leaf samples showed highest quantity for alkaloids, tannin, and carbohydrate at 10.00 % 25.43 % and 11.26 % respectively. The presence of the phytochemical compounds in varying quantities may have contributed to the antibacterial activities of Annona muricata. The study further affirms the potency of A. muricata parts in pharmacognosy and therapeutic applications.","PeriodicalId":194209,"journal":{"name":"Nigerian Journal of Pure and Applied Sciences","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130870549","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Characterization of polycyclic aromatic hydrocarbon (PAH) degrading bacteria and optimization of physicochemical conditions for the production of catechol 1, 2-dioxygenase 多环芳烃(PAH)降解菌的表征及邻苯二酚1,2 -双加氧酶生产的理化条件优化
Nigerian Journal of Pure and Applied Sciences Pub Date : 2023-05-04 DOI: 10.48198/njpas/22.b16
O. Olukunle
{"title":"Characterization of polycyclic aromatic hydrocarbon (PAH) degrading bacteria and optimization of physicochemical conditions for the production of catechol 1, 2-dioxygenase","authors":"O. Olukunle","doi":"10.48198/njpas/22.b16","DOIUrl":"https://doi.org/10.48198/njpas/22.b16","url":null,"abstract":"Biodegradation of recalcitrant polycyclic aromatic hydrocarbons (PAHs) is highly dependent on the activities of catabolic enzyme and the conditions for metabolism. The most significant studies on process optimization of conditions for catechol 1, 2 dioxygenase (C120) metabolism of PAHs used “one variable at a time” (OVAT) method, however, with its limitations. In this study, optimization of conditions for optimal C12O metabolism of PAH pollutants using the central composite design (CCD) of response surface methodology (RSM) was used. Enrichment technique using mineral salt medium (MSM) was used to isolate bacteria from oil-polluted water and soil milleu from Awoye community in Nigeria. Thereafter, the bacterial isolates were primarily screened through growth on mineral salt medium plates supplemented with (100 - 200) mM catechol and were subjected to secondary screening based on their initial catechol 1, 2-dioxygenase activity. Molecular tools were used to identify the isolate. Amongst the five (5) bacterial isolates acquired from primary screening, it was found that the cell free extract from isolate FEP B16a displayed the highest enzyme activity. Additionally, isolate FEP B16a was able to grow on MSM plate with 200 mM catechol. Based on CCD of RSM, the C12O produced from isolate FEP B16a had maximum activity at 35 ℃, pH 8.0, and 80μM of catechol. Molecular analysis confirmed it as a strain of Microbacterium hydrothermale FEP_B16a. This study concluded that CCD of RSM may be an efficient method to optimize C12O activity over the conventional approach of using single variable at a time.","PeriodicalId":194209,"journal":{"name":"Nigerian Journal of Pure and Applied Sciences","volume":"13 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121739513","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparative Studies of Biodegradation of Wastes Using Cellulase from Garden Snails (Limicolaria flammea) and Giant African Snails (Archachatina marginata) 园螺(Limicolaria flammea)和非洲巨螺(Archachatina marginata)纤维素酶生物降解废弃物的比较研究
Nigerian Journal of Pure and Applied Sciences Pub Date : 2022-12-04 DOI: 10.48198/njpas/22.a10
B. S. Fagbohunka, O. S. Adedeji, D. D. Bank-Aluko, M. O. Adeniji, O. A. Olubowale
{"title":"Comparative Studies of Biodegradation of Wastes Using Cellulase from Garden Snails (Limicolaria flammea) and Giant African Snails (Archachatina marginata)","authors":"B. S. Fagbohunka, O. S. Adedeji, D. D. Bank-Aluko, M. O. Adeniji, O. A. Olubowale","doi":"10.48198/njpas/22.a10","DOIUrl":"https://doi.org/10.48198/njpas/22.a10","url":null,"abstract":"The generation of solid waste is a massive and ever-growing problem that affects the entire world, particularly developing countries. In Africa, waste recycling is not fully embraced and performed; as a result, these waste products are viewed as physical contaminants that can harm the ecosystem, generate pollution, and cause a lot of environmental risks. The use of synthetic compounds in the decomposition of wastes could harm the ecosystem and lead to global warming, thus biocatalysts are a preferred option. Cellulase, a hydrolytic enzyme, could digest cellulose, a main component of solid waste. Garden snail (Limicolaria flammea) and Giant Africa snail (Archachatina marginata) are organisms that feed on dead, decaying and actively growing plants due to their possession of cellulolytic enzyme. Cellulase from the gut of Archachatina marginata haemolymph and Limicolaria flammea had specific activities of 1.15 U/mg and 1.14 U/mg respectively. It also showed high level of degradation. Limicolaria flammea haemolymph showed high activity of 504.11% on soluble starch, 529.39% on kick tree and 993.77% on carton paper. This study suggests that cellulase from both Limicolaria flammea and Archachatina marginata has biodegrading potentials on waste materials. While their effects and the rate of degrading wastes differ, they could both be relevant in waste management especially on kitchen waste.","PeriodicalId":194209,"journal":{"name":"Nigerian Journal of Pure and Applied Sciences","volume":"113 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"117249808","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Assessment of Heavy Metals Bioaccumulation in Vegetables Grown in Three Local Government Areas of Kaduna State, Nigeria 尼日利亚卡杜纳州三个地方政府区域种植蔬菜中重金属生物积累的评估
Nigerian Journal of Pure and Applied Sciences Pub Date : 2022-12-04 DOI: 10.48198/njpas/22.a11
Mijinyawa, A., Abdullah, M.A., Wada, Y.A., Junaidu, H.I., Abdulkarim, B.M., Ubazi, C.C., Yahaya, A., Nura, S.
{"title":"Assessment of Heavy Metals Bioaccumulation in Vegetables Grown in Three Local Government Areas of Kaduna State, Nigeria","authors":"Mijinyawa, A., Abdullah, M.A., Wada, Y.A., Junaidu, H.I., Abdulkarim, B.M., Ubazi, C.C., Yahaya, A., Nura, S.","doi":"10.48198/njpas/22.a11","DOIUrl":"https://doi.org/10.48198/njpas/22.a11","url":null,"abstract":"Vegetables are among the major sources of proteins and vitamins in human diets. However, they have high potential for contamination by heavy metals which pose serious public health threats. A study was conducted to assess the levels of heavy metals bioaccumulation in two leafy vegetables: Spinach (Spinacia oleracea) and Cabbage (Brassica oleracea).grown in three local government areas (Giwa, Sabon-gari and Hunkuyi) of Kaduna State. The four heavy metals assessed were: Lead (Pb), Copper (Cu), Cobalt (Co) and Zinc (Zn) in the two leafy vegetables: Atomic Absorption Spectrophotometer (AAS) was used to detect and analyze heavy metals bioaccumulation in the vegetables and soil samples. The sampling locations were selected on the basis of anticipated magnitude of the extent of contamination of the water used for irrigating these vegetables in such areas. The experiment was arranged in completely randomized design with three replications. Data obtained was analyzed using Analysis of Variance with Duncan’s New Multiple Range Test used to separate significant means at 5% level. The result obtained revealed significant difference (P≤0.05) in the heavy metals bioaccumulation in the vegetables and the soils on which they were grown. The result showed that the concentration for Co and Cu were lower than the maximum permissible limits standards as such were non-lethal. However, the accumulation of Pb and Zn in the vegetables was above tolerable limits. This inferred that, vegetables from Sabon-gari, Giwa and Hunkuyi grown along road sides and irrigated with water containing agricultural residues accumulated higher concentration of Pb and Zn. This can be attributed to the intense use of agro-chemicals such as fertilizer and pesticides as well as domestic and industrial discharges in the area. This also suggests a high probability of lethal toxicity due to Pb and Zn in these vegetables. It is therefore recommended that, people should abstain from consuming these heavy metals contaminated vegetables due to significant health implications they posed on to the public health. More so, consumption of vegetables irrigated with waste water or close to road side should be avoided.","PeriodicalId":194209,"journal":{"name":"Nigerian Journal of Pure and Applied Sciences","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129911264","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Seroprevalence of Cytomegalovirus infection among pregnant women in some selected hospitals in Lokoja Metropolis, Kogi State, Nigeria 尼日利亚科吉州洛科贾市一些选定医院孕妇巨细胞病毒感染的血清阳性率
Nigerian Journal of Pure and Applied Sciences Pub Date : 2022-12-04 DOI: 10.48198/njpas/22.a04
Bala, H.E.M., Suleiman, A.B., Tijjani, M.B.
{"title":"Seroprevalence of Cytomegalovirus infection among pregnant women in some selected hospitals in Lokoja Metropolis, Kogi State, Nigeria","authors":"Bala, H.E.M., Suleiman, A.B., Tijjani, M.B.","doi":"10.48198/njpas/22.a04","DOIUrl":"https://doi.org/10.48198/njpas/22.a04","url":null,"abstract":"Cytomegalovirus is one of the most common viruses which causes congenital defects in babies from infected mothers. Sensoneural hearing loss (SNHL) and neurodevelopmental delay are typical occurrences in childhood resulting from congenital defects which presents no symptoms at birth. The aim of this study was to determine the cytomegalovirus IgM infection among pregnant women attending antenatal clinics at KSSH and FMC in Lokoja metropolis, Kogi State, Nigeria. A total of 184 serum samples were collected and analyzed using CMV IgM ELISA kit diagnostic Automation, INC (USA). The study revealed that out of the 184 samples collected, 40 turned out positive for CMV IgM antibodies giving a prevalence of 21.7% while the negative sample result had a prevalence of 78.3%. a total of 92 samples each was collected from both hospitals; KSSH had 30 CMV IgM positive samples having a percentage 32.6% and FMC with 10 CMV IgM having a percentage of 10.86%. Based on the research, there was no significant association between the risk factors such as marital status, type of marriage, occupation and scarification related to the infection. This could be due to the limited number in sample size. Other socio-economic factors that had statistical significant p value with the infection were education (0.035), hand wash (0.027) and previous history of blood transfusion (0.003). The study has shown the need for sensitization of the populace especially to pregnant women, the need for constant and proper personal hygienic practices be done to reduce the risk of infection and possibly stop its transmission to fetus. In addition, inclusion of screening for cytomegalovirus antibodies among blood donors may be useful tool in preventing transmission of cytomegalovirus to blood recipients.","PeriodicalId":194209,"journal":{"name":"Nigerian Journal of Pure and Applied Sciences","volume":"28 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125021415","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Growth, Biomass and Nickel Accumulation Assessments of Amaranthus hybridus and Celosia argentea grown in Nickel Contaminated Soil 在镍污染土壤中生长的苋菜和银芹的生长、生物量和镍积累评价
Nigerian Journal of Pure and Applied Sciences Pub Date : 2022-12-04 DOI: 10.48198/njpas/22.b02
Kehinde G Olawepo, A. S. Oluwatobi, Damilola R. Awotunde, P. Fatoba
{"title":"Growth, Biomass and Nickel Accumulation Assessments of Amaranthus hybridus and Celosia argentea grown in Nickel Contaminated Soil","authors":"Kehinde G Olawepo, A. S. Oluwatobi, Damilola R. Awotunde, P. Fatoba","doi":"10.48198/njpas/22.b02","DOIUrl":"https://doi.org/10.48198/njpas/22.b02","url":null,"abstract":"Agricultural lands used in the cultivation of vegetables are prone to contamination with heavy metals of different degrees, which could impact significantly the physiological performance of the plants, and amassing of these metals. This study was conducted at the botanical garden of the Department of Plant Biology, University of Ilorin, to appraise the effects of nickel contamination on identified growth parameters of Amaranthus hybridus and Celosia argentea, their biomass and nickel accumulated in the vegetables. The treatment comprised of varying concentrations of nickel (100, 200 and 400 mg/kg) used to pollute soil, while control soil were not contaminated. Growth parameters (stem length and girth, leaf length and breadth, number of leaves; and wet and dry weights) were evaluated. Elemental concentrations of nickel in both plants were determined using Atomic Absorption Spectrophotometer. Celosia argentea planted on soil polluted with 100 mg/kg of nickel recorded peak values for leaf length and breadth and number of leaves at 3 weeks after transplanting (WAT) (4.77 cm, 2.68 cm and 11.83) respectively. Amaranthus hybridus grown on untreated soil recorded the maximum stem length at 1, 2 and 3 WAT (3.50, 3.80 and 5.15 cm) respectively. Celosia argentea and Amaranthus hybridus grown on soil polluted with 200 and 100 mg/kg of nickel recorded the highest dry weights of 0.06 and 3.87 g respectively at 1 WAT. The highest values of nickel concentrations in Celosia argentea and Amaranthus hybridus were recorded in those planted in soil polluted with 200 mg/kg of nickel (3.90 and 3.87 mg/kg respectively). The study revealed that nickel pollution may promote the performance of Celosia argentea and Amaranthus hybridus when cultivated below the threshold of 200 mg/kg which has been established in this study to also enhance build up of nickel in the tissues of the botanicals.","PeriodicalId":194209,"journal":{"name":"Nigerian Journal of Pure and Applied Sciences","volume":"123 2","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133684676","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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