Oftalmologicheskii zhurnal最新文献

{"title":"Blood selectin levels as a predictive factor for diabetic retinopathy and diabetic macular edema in type 2 diabetes","authors":"С.О. Риков, Д.І. Чугаєв, С.В. Зяблинцев","doi":"10.31288/oftalmolzh202331926","DOIUrl":"https://doi.org/10.31288/oftalmolzh202331926","url":null,"abstract":"Background: Diabetes mellitus (DM) is still a noninfectious global pandemic. Diabetic retinopathy (DR) is one of the most common and socially significant complications of both type 1 and type 2 diabetes. Predicting the probability of DR progression and potential diabetic macular edema (DME) development is still important. Currently available predictive models include a wide number of predictors, and such predictors as blood selectin levels seem to be promising.\u0000\u0000Purpose: To determine relationships between blood levels of selectins and DR progression and DME development in patients with T2DM, and to develop particular predictive models.\u0000\u0000Material and Methods: Of the 124 patients (124 eyes) involved into this study, 95 (95 eyes) had T2DM and retinopathy (group 1 of 29 eyes with mild non-proliferative DR (NPDR); group 2 of 35 eyes with moderate or severe non-proliferative NPDR; and group 3 of 31 eyes with proliferative DR (PDR)), and 29 (29 eyes) had no diabetes (controls). Patients underwent a routine eye examination and spectral domain optical coherence tomography (SD-OCT) to determine central retinal thickness (CRT). The presence of DME was based on an increased macular thickness in the Early Treatment Diabetic Retinopathy Study (ETDRS) subfields compared to the upper limit of normal for patient's age and gender. Enzyme-linked immunosorbent assay (ELISA) kits from Invitrogen Thermo Fisher Scientific (USA) were used to determine selectin levels in blood. Statistical analyses were conducted using MedStat and MedCalc v.15.1 (MedCalc Software bvba) software.\u0000\u0000Results: There was a statistically significant tendency for an increase in progression of DR to be accompanied by an increase in blood selectin levels. In the presence of DME, blood LS levels were statistically significantly increased in mild NPDR; blood PS levels, in PDR; and blood ES levels, in all stages of DR. A regression model for predicting the progression of DR was built. In the model developed, diabetes duration and blood selectin levels were positively correlated, while HbA1c level was inversely correlated with DR progression. The model was found to be adequate R2adjust = 0.84; F = 97.9, p less 0.001, demonstrating high correlation of the selected independent variables with the stage of DR. The calculated Y index may be considered a quantitative reflection of the severity of DR. A patient is predicted to have mild NPDR (with a prediction accuracy of 86.2%) if Y less 1.5, moderate of severe NPDR (with a prediction accuracy of 88.6%) if 1.5 less equal Y less 2.35, and PDR (with a prediction accuracy of 100%) if Y more equal 2.35. A regression model for predicting the development of DME was built, with CRT and blood ES level found to increase the risk of the development of DME. A high AUC value for the ROC curve (AUC = 0.97; 95% CI, 0.92-0.99) indicated a very strong correlation of the risk of DME development with the levels of selected independent variables. In addition, sensitivity and ","PeriodicalId":19419,"journal":{"name":"Oftalmologicheskii zhurnal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47361110","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"In Memoriam: Prof. Olena Petrivna Sotnikova","authors":"Світлана Полякова","doi":"10.31288/oftalmolzh2023380","DOIUrl":"https://doi.org/10.31288/oftalmolzh2023380","url":null,"abstract":"Professor Olena Petrivna Sotnikova, Head of Pharmacology and Tissue Therapy Laboratory at the Filatov Institute of Eye Diseases and Tissue Therapy, passed away on June 9, 2023.\u0000\u0000She was born in the town of Makiivka, Donetsk region, on June 26, 1939. After graduating cum laude from the Faculty of General Medicine, Odesa Medical Institute, in 1969, Olena Petrivna began her career as a junior research associate at the Pharmacology and Tissue Therapy Laboratory at the Filatov Institute of Eye Diseases and Tissue Therapy, NAMS of Ukraine.\u0000\u0000Completing her Cand Sc (Med) thesis, Cytochemical Changes in the Corneal Epithelium and Nasal Mucosa in Impaired Sensory Innervation, under the co-supervision of Drs Sc (Med) V.D. Dragomiretskyi and R.K. Marmur, was her first serious achievement in science. In 1981, O.P. Sotnikova was awarded with a silver medal and the Certificate of Participation in the Exhibition of Economic Achievements of the USSR as a co-developer of a preparation named “aloe tablets covered with a film shell”.\u0000\u0000She defended her Dr Sc (Med) dissertation and became head of the Pharmacology and Tissue Therapy Laboratory in 1990 and was promoted to professorship in 1999. Professor Sotnikova’s study on molecular and cellular bioregulative and protective mechanisms of tissue preparations in the presence of the impact of adverse factors on the body has become an important contribution to the Acad. Filatov’s fundamental theory of “biogenic stimulators”. Two components had been incorporated into the science and practice activities of the laboratory under her guidance: first, the ocular pharmacological research aimed at the development of single and multicomponent ophthalmic dosage forms from national plant, animal and geo-organic raw materials, and, second, the preclinical evaluation of the curative and preventive efficacy of these forms in ophthalmopathy models.\u0000\u0000Twelve individuals completed their Cand Sc (Med) degrees under the supervision of Prof. Sotnikova. She produced about 400 publications and authored or co-authored 20 patents.\u0000\u0000Olena Petrivna was a person with a capital P. She was a remarkably talented scientist and manager, and her job was her passion. She also was a benevolent and empathetic person who had never remained indifferent to the problems of others and was always ready to assist in any way she could.\u0000\u0000Olena Petrivna’s memory will leave on forever through her numerous published works, scientific ideas and research results, and the apprentices that she mentored.","PeriodicalId":19419,"journal":{"name":"Oftalmologicheskii zhurnal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46185147","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"In Memoriam: Prof. Valerii Viktorovych Vit","authors":"Світлана Полякова","doi":"10.31288/oftalmolzh2023379","DOIUrl":"https://doi.org/10.31288/oftalmolzh2023379","url":null,"abstract":"The legendary professor Valerii Viktorovych Vit passed away on April 22, 2023.\u0000\u0000He was born in Odesa in 1948.\u0000\u0000After graduating from the Faculty of General Medicine, Odesa Medical Institute, in 1972, Vit worked some time as a dissector at Odesa Regional Hospital.\u0000\u0000He began his science career at the Filatov Institute of Eye Diseases and Tissue Therapy in 1975 as a junior research associate at the Pathomorphology Laboratory, became head of the laboratory in 1978 and was promoted to the Deputy Director for Science at the institute in 1991.\u0000\u0000Valerii Viktorovych Vit defended his Cand Sc (Med) thesis in 1978, and doctoral (Dr Sc (Med)) dissertation, The Pathological Anatomy and Therapeutic Pathomorphosis of Human Pigmented Uveal Tumors, in 1986. The dissertation research was conducted under Professor V.V. Voino-Yasenetskyi, an outstanding scientist, and focused on the morphogenesis and malignancy of human choroidal and ciliary tumors. Valerii Viktorovych Vit was promoted to professorship in 1989.\u0000\u0000He authored or co-authored about 400 papers and five monographs on visual system structure and the pathological anatomy of eye disease. Five individuals completed their Dr Sc (Med) degrees, and 18, their Cand Sc (Med) degrees, under the supervision or mentorship of Prof. Vit.\u0000\u0000He was the first to raise questions on the value of ocular oncology studies on (a) the transformation of an eye tumor in the course of treatment and (b) the efficacy of the therapy used for treatment.\u0000\u0000He will be remembered as an exceptionally talented doctor, scientist and manager of high competence and great professional experience and a person with a strong commitment to work.\u0000\u0000By his pupils and colleagues, Professor Vit, a true professional in his field, will remain a cherished memory. We offer our condolences to his family and loved ones.","PeriodicalId":19419,"journal":{"name":"Oftalmologicheskii zhurnal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42983854","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correlation between optical coherence tomography angiography-based data and postoperative visual acuity in patients that underwent surgery for macula-on RRD and macula-off RRD","authors":"Ірина Безкоровайна, Анна Іванченко","doi":"10.31288/oftalmolzh202334248","DOIUrl":"https://doi.org/10.31288/oftalmolzh202334248","url":null,"abstract":"Background: Despite advances in surgical techniques for rhegmatogenous retinal detachment (RRD) repair, patients are still at high risk for low functional outcomes. Given the above, it is important to find reasons for disappointment at the outcomes of vitreoretinal surgery for RRD. Impaired retinal microcirculation is a possible cause of insufficiently good functional outcomes in surgery for RRD.\u0000\u0000Purpose: To compare postoperative optical coherence tomography angiography (OCTA)-based changes in retinal microcirculation in the eyes of patients that underwent surgery for macula-on RRD versus the eyes of patients that underwent surgery for macula-off RRD and (2) to establish a relationship between OCTA data and best-corrected visual acuity (BCVA).\u0000\u0000Material and Methods: This prospective study included 116 patients. Of these, 65 underwent surgery for macular-on RRD (group 1) and 51, surgery for macular-off RRD (group 2). OCTA-based retinal vasculature parameters (foveal avascular zone (FAZ) area, parafoveal superficial capillary plexus (SCP) density and deep capillary plexus (DCP) density, vessel diameter, and vessel tortuosity index (VTI)) and their correlation with BCVA were assessed. Follow-up duration was 12 months.\u0000\u0000Results: In group 1, there was a negative correlation between the FAZ area and the macular thickness (r = - 0.299, p = 0.025) at month 12. The final BCVA was associated with the parafoveal DCP density (r = - 0.340, p = 0.010) and FAZ area (r= 0.390, p = 0.003). At 12 months, in group 2, the BCVA negatively correlated with the FAZ area (r = - 0.408, p = 0.012) and parafoveal SCP density (r = - 0.451, p = 0.005). In addition, there was a negative correlation between the parafoveal DCP density and the postoperative BCVA (r = - 0.418). There was no correlation between the FAZ area and the macular thickness (r = - 0.282, p = 0.080).\u0000\u0000Conclusion: The poorer vessel tortuosity index and parafoveal vessel density and diameter, the lower was postoperative visual acuity.","PeriodicalId":19419,"journal":{"name":"Oftalmologicheskii zhurnal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48577608","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bacterial keratitis caused by Kocuria varians: a case report","authors":"Василь Сакович, О. Б. Алексєєва, Сергій Волок, Оксана Іщенко","doi":"10.31288/oftalmolzh202337173","DOIUrl":"https://doi.org/10.31288/oftalmolzh202337173","url":null,"abstract":"The purpose of this paper is to report a rare case of bacterial keratitis caused by the non-pathogenic Kocuria varians. The case reported exemplifies the development of severe bacterial keratitis following a corneal microtrauma induced by of non-pathogenic or potentially pathogenic species. We report a rare cause of Kocuria varians keratitis in a review of national and foreign literature. Examination of the corneal microbiota and determination of its spectrum of sensitivity to antibiotics, if performed early, will facilitate the administration of adequate treatment and prevention of severe complications in corneal bacterial lesions.","PeriodicalId":19419,"journal":{"name":"Oftalmologicheskii zhurnal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44641393","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Preconditioning-induced retinal protection appears promising: a review","authors":"Олег Задорожний, Андрій Король, Наталія Пасєчнікова","doi":"10.31288/oftalmolzh202336170","DOIUrl":"https://doi.org/10.31288/oftalmolzh202336170","url":null,"abstract":"Like human and animal myocardium and cerebral nervous tissue, the human and animal retina has powerful intrinsic adaptive mechanisms which can improve cell protection under adverse conditions. These endogenous protective mechanisms are capable of improving the resistance of retinal cells to adverse factors and can be triggered by brief episodes of different subthreshold stimuli (ischemia, photobiomodulation, hypothermia, etc.) preceding a subsequent more sustained injury, a process which is called preconditioning. Results of years of laboratory and clinical studies have demonstrated amazing cardiac protection and cerebral protection opportunities from preconditioning. Although the results of in vivo preclinical studies of retinal conditioning are promising, the benefits from the found effects of preconditioning on the protection of the human retina are still to be assessed. The overview presented highlights some aspects of the research and use of protective effects of preconditioning in various fields of medicine. The results of laboratory studies of endogenous mechanisms of retinal cell protection are discussed herein, along with our recommendations for prospective areas of future use of the effects in cinical ophthalmology for retinal protection.","PeriodicalId":19419,"journal":{"name":"Oftalmologicheskii zhurnal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48462240","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Review on imaging methods in non-infectious posterior uveitis, principles, relevance, and practical clinical applications to disease entities","authors":"I. Papasavvas, Carl P. Herbort Jr","doi":"10.31288/oftalmolzh20233959","DOIUrl":"https://doi.org/10.31288/oftalmolzh20233959","url":null,"abstract":"The work-up and diagnosis of posterior uveitis rely heavily on multiple imaging methods that have become available beyond the mere photographic imaging and fluorescein angiography (FA) used to image uveitis in the past. Global assessment and precise follow-up of posterior uveitis were achieved with the development of indocyanine green angiography (ICGA) since the mid-1990ties that, together with FA, made it possible to perform dual FA and ICGA giving information on both the retina and the choroidal compartment. Further non-invasive imaging methods were developed subsequently that contributed to additional valuable information completing the dual FA/ICGA basic appraisal of uveitis, including (1) optical coherence tomography (OCT) giving a quasi-histological  morphology of retinal structures of the posterior pole, (2) enhanced-depth imaging OCT (EDI-OCT) allowing to image the choroidal compartment and (3) blue light fundus autofluorescence (BAF) showing the integrity or damage of the retinal pigment epithelium, the photoreceptors and the outer retina. OCT-angiography (OCT-A) became available more recently and presented the advantage to image the retinal and choroidal circulations without needing dye injections, necessary for dual FA/ICGA. This review article will illustrate the principles, relevance and practical applications of these different imaging methods used in uveitis by examining the main categories of  non-infectious posterior uveitis entities including (1) retinal inflammatory disorders, inflammatory diseases of the outer retina and of the choriocapillaris (choriocapillaritis) and stromal choroiditis.","PeriodicalId":19419,"journal":{"name":"Oftalmologicheskii zhurnal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43166884","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Реґіонарна гемодинаміка ока при невриті зорового нерва","authors":"Наталя Храменко, Наталія Романівна Коновалова, Тетяна Серебріна, О. С. Іваницька","doi":"10.31288/oftalmolzh20232310","DOIUrl":"https://doi.org/10.31288/oftalmolzh20232310","url":null,"abstract":"Актуальність. У структурі причин інвалідності запальні захворювання зорового нерва становлять до 28%. Сучасні дослідження вказують на порушення гемодинаміки при невриті зорового нерва (НЗН), однак результати досліджень суперечливі, як і дані про патофізіологію судинних порушень.Мета: вивчити стан реґіонарної гемодинаміки методом реоофтальмографії й реоенцефалографії у хворих на ідіопатичний неврит зорового нерва та його ускладнені наслідки. Матеріал і методи. На базі відділу запальної патології ока й лабораторії функціональних методів дослідження органу зору ДУ «Інститут очних хвороб і тканинної терапії ім. В. П. Філатова НАМНУ» обстежено 57 пацієнтів з НЗН невизначеної етіології. Пацієнти поряд із клінічним офтальмологічним обстеженням пройшли реоофтальмографію, реоенцефалографію на комп’ютерному комплексі Реоком (Харків). Результати. Гострота зору (ГЗ) за найкращої корекції у хворих при виході НЗН з ураженням зони макули була знижена у 2–3 рази порівняно з гострим і затяжним періодами перебігу НЗН. Прямий кореляційний зв’язок між ГЗ та об’ємним пульсовим кровонаповненням ока (RQ, ‰) становив r=0,24 (р<0,05), зворотний кореляційний зв’язок ГЗ з наявністю ускладнень як наслідків НЗН – r=-0,35 (р<0,05). RQ в гострий період НЗН був вищий на 15,5% порівняно з контрольною групою й вищим порівняно з переходом НЗН у часткову атрофію зорового нерва (ЧАЗН) та НЗН з ураженням зони макули на 35% і 31% відповідно. RQ в групі ЧАЗН був нижчим за контроль на 23,6%, що відображає реґіонарний ішемічний процес. За статистичним показником OR (відношення шансів) шанс зниження RQ при переході НЗН у ЧАЗН підвищений у середньому в 9,2 раза (р<0,05) із 95% ДІ (2,0–42,4 раза), а при наслідках НЗН з ураженням зони макули – у 4,3 раза (р<0,05) із 95% ДІ (1,2–14,7 раза) порівняно з гострим НЗН. Об’ємне пульсове кровонаповнення судин головного мозку в басейні внутрішньої сонної артерії за показником РІ (%) у гострий період НЗН відповідало нормі, а в затяжний період і період завершення НЗН збільшувалося на 44 %. Еластотонічні властивості великих судин по всіх басейнах головного мозку за показником α (%) у гострий період відповідали нормі, після завершення невриту з ускладненнями значно підвищувалися в середньому на 15%. Тонічні властивості дрібних судин при НЗН та його наслідків підвищені за показниками ДКІ (%) і ДСІ (%) на 32,2 та 55% відповідно.Висновки. Виявлено особливості гемодинаміки ока та мозку в гострий і затяжний періоди перебігу НЗН, а також його наслідки з ускладненнями.","PeriodicalId":19419,"journal":{"name":"Oftalmologicheskii zhurnal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44520520","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Перспективний захист сітківки прекондиціюванням: огляд літератури","authors":"Олег Задорожний, Андрій Король, Наталія Пасєчнікова","doi":"10.31288/oftalmolzh202323138","DOIUrl":"https://doi.org/10.31288/oftalmolzh202323138","url":null,"abstract":"Використання адаптивної оптики (АО) забезпечує нові унікальні можливості прижиттєвої візуалізації судин сітківки. Детальні зображення судин сітківки, отримані за допомогою АО, можуть успішно застосовуватися як один із компонентів мультимодальної візуалізації різної патології сітківки, доповнюючи дані класичних методів діагностики. Перспективна неінвазивна візуалізація структур очного дна за допомогою АО дозволяє якісно та кількісно оцінити ранні ознаки ремоделювання судин сітківки, пов’язані з віком, артеріальною гіпертензією, цукровим діабетом та іншими захворюваннями.","PeriodicalId":19419,"journal":{"name":"Oftalmologicheskii zhurnal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43757132","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An unusual case of posterior vitreous detachment","authors":"Bruno Barbosa Ribeiro, João Oliveira Leite, A. Meireles, Miguel Mesquita Neves","doi":"10.31288/oftalmolzh202326062","DOIUrl":"https://doi.org/10.31288/oftalmolzh202326062","url":null,"abstract":"Purpose: To describe a case of spontaneous closure of a macular microhole induced by an acute posterior vitreous detachment (PVD).\u0000Methods: Retrospective case report and analysis of patient data.\u0000Case Report: We present a case of spontaneous closure of a posterior vitreous detachment (PVD) induced macular microhole. In our patient, macular microhole developed a few weeks after acute PVD. The development of macular hole secondarily to acute PVD is rare, and there are reports of spontaneous closure. Reporting this case is important to alert clinicians to the potential self-resolving nature of this pathology.\u0000Conclusion: Macular hole is a rare complication of acute PVD. Some cases resolve spontaneously without the need for surgical correction. A conservative approach may be an appropriate setting if no high-risk features are present.","PeriodicalId":19419,"journal":{"name":"Oftalmologicheskii zhurnal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44557599","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}