Luo-Xiang Fang , Tao Yao , Peng Zheng , Zi Tao , Yuan-Nan Lin
{"title":"Association of nutritional status and mortality in a population with cardiovascular disease: Predictive role of CONUT score","authors":"Luo-Xiang Fang , Tao Yao , Peng Zheng , Zi Tao , Yuan-Nan Lin","doi":"10.1016/j.orcp.2025.10.009","DOIUrl":"10.1016/j.orcp.2025.10.009","url":null,"abstract":"<div><h3>Background</h3><div>The prognosis of patients with cardiovascular disease (CVD) is related to nutritional status, but how to accurately evaluate nutritional status still remains undetermined.</div></div><div><h3>Method</h3><div>4441 participants with CVD from the National Health and Nutrition Examination Survey 1999–2018 were included. Controlling Nutritional Status (CONUT) score and Naples Prognostic Score (NPS) were calculated to assess nutritional status of patients with CVD. Cox proportional hazards analysis was used to investigate associations between different nutritional scores and mortality of patients with CVD. Receiver operating characteristic curves were used to compare the predictive abilities of nutritional scores for 1-year mortality. Mediation analyses were conducted to explore effects of systemic immune-inflammation index (SII) on the association between nutritional scores and mortality.</div></div><div><h3>Result</h3><div>A high CONUT score was associated with an increased risk of cardiovascular mortality (p < 0.001), whereas a high NPS score was not. ROC curves demonstrated both CONUT and NPS scores performed better than BMI after considering age and gender in predicting 1-year mortality in patients with CVD (AUC: all-cause: CONUT: 0.678, NPS: 0.694, BMI: 0.654; cardiovascular: CONUT: 0.703, NPS: 0.701, BMI: 0.646)). Mediating analysis revealed that SII mediated 15.2 % and 10.9 % of the association between CONUT and all-cause and cardiovascular death, respectively.</div></div><div><h3>Conclusion</h3><div>Poor nutritional status increased the risk of all-cause and cardiovascular mortality in patients with CVD, mediated partially by SII. CONUT score may serve as a more effective screening tool for prognosis.</div></div>","PeriodicalId":19408,"journal":{"name":"Obesity research & clinical practice","volume":"19 6","pages":"Pages 490-496"},"PeriodicalIF":2.5,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145445051","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Chong Xu , Song Zhao , Jiamin Tang , Jun Han , Han Zhang , Weijing Liu , Yifan Zhao , Yawei Xu , Yi Zhang
{"title":"Associations between different anthropometric measures and major adverse cardiovascular events among the elderly in China","authors":"Chong Xu , Song Zhao , Jiamin Tang , Jun Han , Han Zhang , Weijing Liu , Yifan Zhao , Yawei Xu , Yi Zhang","doi":"10.1016/j.orcp.2025.10.010","DOIUrl":"10.1016/j.orcp.2025.10.010","url":null,"abstract":"<div><h3>Background and Aims</h3><div>Overweight and obesity in the elderly are independently associated with an increased risk of cardiovascular mortality. However, beyond body mass index (BMI), other anthropometric measures such as waist-to-hip ratio (WHR) may provide a better indication of body fat distribution and may be especially useful in a geriatric population. This study explored the value of anthropometric indices in predicting major adverse cardiovascular events (MACE) among older adults.</div></div><div><h3>Methods and Results</h3><div>3285 participants aged 65 years or older were included in this analysis. Eight anthropometric measures, including weight-related and weight-free measures, were measured and calculated. MACE included nonfatal myocardial infarction, nonfatal stroke or cardiovascular death. Median follow-up was 5.4 years with 218 events observed. Participants with obesity (BMI ≥ 28 kg/m<sup>2</sup>) were associated with a higher MACE risk compared with those with normal weight (adjusted Hazard Ratio (aHR) = 1.54, 95 % confidence interval (CI): 1.07–2.22, P = 0.020). Restricted cubic splines confirmed the robust correlation between high BMI and MACE risk. Similarly, the aHR for MACE in WHR quartile 4 versus quartile 1 was 1.96 (95 % CI: 1.26–3.05, P = 0.003). Results were unchanged when WHR was continuous. In adjusted models, all four weight-free measures were significantly associated with increased MACE risk (all P < 0.05), while only two weight-related measures were significant.</div></div><div><h3>Conclusions</h3><div>In the elderly, weight-free measures may be more relevant to the risk of MACE.</div></div><div><h3>Clinical Trial Registration</h3><div>NCT02368938</div></div>","PeriodicalId":19408,"journal":{"name":"Obesity research & clinical practice","volume":"19 6","pages":"Pages 497-502"},"PeriodicalIF":2.5,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145482748","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Sex-specific associations of body mass index with quadriceps neuromuscular function and self-reported function in individuals with and without patellofemoral pain","authors":"Sungwan Kim , Jihong Park","doi":"10.1016/j.orcp.2025.11.003","DOIUrl":"10.1016/j.orcp.2025.11.003","url":null,"abstract":"<div><h3>Objective</h3><div>To examine the association of body mass index (BMI) with quadriceps neuromuscular function and self-reported function in individuals with and without patellofemoral pain (PFP).</div></div><div><h3>Methods</h3><div>This cross-sectional study included 100 participants (50 PFP, 50 pain-free; evenly split by sex), who were evaluated for BMI, quadriceps neuromuscular function (strength, central activation ratio [CAR], rate of torque development [RTD], and endurance), and self-reported function (Lower Extremity Functional Scale). The association of BMI with quadriceps neuromuscular function and self-reported function was assessed using bivariate correlation analysis, followed by hierarchical regression analysis (covariates: age, physical activity level, pain laterality, pain duration, and pain severity for PFP; age and physical activity level for pain-free).</div></div><div><h3>Results</h3><div>Higher BMI was associated with lower quadriceps strength (ρ = –0.445; <em>P</em> = .026), slower quadriceps RTD (r = –0.643; <em>P</em> < .001), and poorer self-reported function (r = –0.446; <em>P</em> = .025) among females with PFP; however, higher BMI was only associated with poorer self-reported function (r = –0.401; <em>P</em> = .047) among males with PFP. No significant associations were detected among pain-free females; however, higher BMI was associated with lower quadriceps CAR (ρ = –0.431; <em>P</em> = .032) among pain-free males. After adjusting for covariates, BMI uniquely explained 47 % of the variance in quadriceps RTD (ΔF = 18.73; <em>P</em> < .001) among females with PFP. No other significant regression effects were detected.</div></div><div><h3>Conclusions</h3><div>Higher BMI is associated with lower quadriceps neuromuscular function and poorer self-reported function, especially in females with PFP. In particular, BMI accounts for nearly half of the variance in quadriceps RTD in females with PFP.</div></div>","PeriodicalId":19408,"journal":{"name":"Obesity research & clinical practice","volume":"19 6","pages":"Pages 518-525"},"PeriodicalIF":2.5,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145574110","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Cross-sectional and longitudinal associations of weekly step patterns with metabolic syndrome in middle-aged and older Japanese adults: The Toon Health Study","authors":"Naofumi Yamamoto , Koutatsu Maruyama , Isao Saito , Kiyohide Tomooka , Takeshi Tanigawa , Ryoichi Kawamura , Yasunori Takata , Haruhiko Osawa","doi":"10.1016/j.orcp.2025.10.008","DOIUrl":"10.1016/j.orcp.2025.10.008","url":null,"abstract":"<div><h3>Background</h3><div>We examined whether daily step count and the frequency of achieving ≥ 8000 steps/day, independently and in combination, are associated with the prevalence and 5-year incidence of metabolic syndrome (MetS) in middle-aged and older adults.</div></div><div><h3>Methods</h3><div>Cross-sectional (n = 1723) and 5-year prospective (n = 977) analyses were conducted. Daily steps were recorded over 7 consecutive days at baseline using a pedometer. Average daily steps were classified as < 6000, 6000–7999, 8000–10,000, or > 10,000. Each category was stratified into high- or low-frequency subgroups according to the proportion of days with ≥ 8000 steps. Logistic regression, adjusted for potential confounders, was used to assess associations with MetS.</div></div><div><h3>Results</h3><div>Higher step categories were consistently associated with lower odds of MetS in both cross-sectional and 5-year follow-up analyses (<em>p</em> for trend <0.05). A greater frequency of days achieving ≥ 8000 steps was also associated with lower MetS risk, although this effect diminished after adjustment for average step count. In both cross-sectional and longitudinal analyses, the high-frequency subgroup within the 8000–10,000 steps/day category consistently showed lower odds of MetS than the low-frequency subgroup.</div></div><div><h3>Conclusion</h3><div>Total step volume showed a stronger association with MetS than step frequency. Nonetheless, regularly achieving step thresholds may be associated with potential benefits within specific activity ranges.</div></div>","PeriodicalId":19408,"journal":{"name":"Obesity research & clinical practice","volume":"19 6","pages":"Pages 511-517"},"PeriodicalIF":2.5,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145431621","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Xinyue Lu , Yuanyuan Huang , Lianhong Ji , Dong Chen , Xiaoyang Lian , Xu Li , Xinyi Yang , Sihan Niu , Lingzhun Wang , Mengqian Yuan
{"title":"Signal identification of adverse reactions related to phentermine/topiramate: A study based on FAERS reports","authors":"Xinyue Lu , Yuanyuan Huang , Lianhong Ji , Dong Chen , Xiaoyang Lian , Xu Li , Xinyi Yang , Sihan Niu , Lingzhun Wang , Mengqian Yuan","doi":"10.1016/j.orcp.2025.11.005","DOIUrl":"10.1016/j.orcp.2025.11.005","url":null,"abstract":"<div><h3>Objectives</h3><div>The phentermine/topiramate combination represents one of the most effective anti-obesity therapies under investigation; however, its safety profile requires further exploration. This study aimed to systematically analyze adverse events (AEs) associated with phentermine/topiramate using the FDA Adverse Event Reporting System (FAERS) database, identify potential safety signals, and provide evidence to inform safer clinical decision-making.</div></div><div><h3>Methods</h3><div>Reports related to phentermine/topiramate were extracted from the FAERS database covering the period between the third quarter of 2012 and the fourth quarter of 2024. After data cleaning and standardization, four signal detection methods were applied separately to analyze adverse events: Reporting Odds Ratio (ROR), Proportional Reporting Ratio (PRR), Bayesian Confidence Propagation Neural Network (BCPNN), and Multi-Item Gamma Poisson Shrinker (MGPS).</div></div><div><h3>Results</h3><div>A total of 5173 AE reports associated with phentermine/topiramate were identified, encompassing 23 System Organ Class (SOC) categories. Among these, 104 Preferred Terms (PTs) met the criteria across all four signal detection algorithms. The top 30 PTs with the highest signal strength are summarized in Table 2. Symptoms listed in the prescribing information were broadly categorized into three groups: ocular disorders, emotional and psychological disorders, and metabolic disorders. Moreover, several PTs—including polycystic ovary syndrome (PCOS) (ROR 272.43), tongue bleeding (ROR 15.15), binge eating (ROR 59.39), and impaired glucose tolerance (ROR 11.75)—emerged as novel safety signals not previously documented in the prescribing information.</div></div><div><h3>Conclusions</h3><div>The phentermine/topiramate combination demonstrates significant efficacy for weight loss; however, its adverse reaction profile is varied in type and severity, with some events not explicitly listed in the prescribing information, underscoring the need for cautious clinical application.</div></div>","PeriodicalId":19408,"journal":{"name":"Obesity research & clinical practice","volume":"19 6","pages":"Pages 536-543"},"PeriodicalIF":2.5,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145678408","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"More warning labels, fewer calories: An exploratory study in Mexican undergraduate men","authors":"Damaris García-Hernández , Antonio Laguna-Camacho","doi":"10.1016/j.orcp.2025.09.001","DOIUrl":"10.1016/j.orcp.2025.09.001","url":null,"abstract":"<div><div>The present study addressed whether the number of front-of-package warning labels relates to actual food intake. A total of 400 male undergraduates in Mexico tasted 12 food/drink products, each with 0–4 warning labels. Calorie intake was measured in a controlled experimental setting, with warning labels left visible or covered. Across 4800 product-level observations, a small but consistent negative correlation emerged: more visible warning labels led to fewer calories consumed, a result decisively supported by Bayesian analysis. Findings show that warning labels act cumulatively as risk signals that impact real energy consumption, supporting their use as public health tool.</div></div>","PeriodicalId":19408,"journal":{"name":"Obesity research & clinical practice","volume":"19 5","pages":"Pages 453-454"},"PeriodicalIF":2.5,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145054794","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Kelli M. Richardson, Michelle R. Jospe, Jessie Somerville, Julia Felrice, Susan M. Schembre
{"title":"Understanding the benefits and psychological burdens of using continuous glucose monitoring for lifestyle change: A mixed-methods cross-sectional study","authors":"Kelli M. Richardson, Michelle R. Jospe, Jessie Somerville, Julia Felrice, Susan M. Schembre","doi":"10.1016/j.orcp.2025.10.003","DOIUrl":"10.1016/j.orcp.2025.10.003","url":null,"abstract":"<div><h3>Background</h3><div>Continuous glucose monitoring (CGM) is increasingly used by people with and without diabetes to support lifestyle change. While CGM’s efficacy as a behavior change tool is proven, its potential to cause distress remains underexplored. This study assessed CGM-related distress in adults not using insulin and examined associations with baseline characteristics, psychological traits, and qualitative experiences.</div></div><div><h3>Methods</h3><div>A multi-method, cross-sectional digital questionnaire was administered to adults with and without diabetes not on insulin who had used CGM within the past year. Quantitative data included participant characteristics, psychological traits, and ratings of CGM-related distress. Qualitative data were gathered through five open-ended questions and analyzed thematically.</div></div><div><h3>Results</h3><div>Fifty-six adults were included. CGM-related distress varied widely. Regardless of diabetes status, more than two-thirds of participants (68 %) reporting fear of type 2 diabetes when observing high glucose levels. Younger age and obesity were associated with greater distress (p < 0.01). <em>Agreeableness</em> was associated with greater fear and unhappiness in response to observing elevated glucose levels (<em>r</em> > 0.3, <em>p</em> < 0.01), while higher eating disorder symptoms correlated with distress over CGM’s appearance (<em>r</em> > 0.3; <em>p</em> < 0.01). Qualitative themes revealed that despite distress, most participants (89 %) reported positive dietary and/or physical activity changes in response to CGM.</div></div><div><h3>Conclusions</h3><div>While CGM facilitates healthy lifestyle changes, it may also contribute to distress, particularly among younger adults and those with obesity, high agreeableness and eating disorder symptoms. Qualitative findings indicated distress often coexisted with reported behavior change, suggesting it may act as a motivator and barrier. Future research should develop validated tools to measure CGM-related distress and clarify its role in behavior change.</div></div>","PeriodicalId":19408,"journal":{"name":"Obesity research & clinical practice","volume":"19 5","pages":"Pages 417-426"},"PeriodicalIF":2.5,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145308817","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Herul Wahyudin, M. Ramli, Tutut Chusniyah, Nur Eva, Maria Oktasari
{"title":"Digital prehabilitation and cognitive interventions to reduce surgical risk in patients with obesity","authors":"Herul Wahyudin, M. Ramli, Tutut Chusniyah, Nur Eva, Maria Oktasari","doi":"10.1016/j.orcp.2025.10.002","DOIUrl":"10.1016/j.orcp.2025.10.002","url":null,"abstract":"","PeriodicalId":19408,"journal":{"name":"Obesity research & clinical practice","volume":"19 5","pages":"Pages 455-456"},"PeriodicalIF":2.5,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145275460","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sally Badorrek , Janet Franklin , Michael Devadas , Nicholas Williams , Rachel Russell , Supreet Saluja , Marijka Batterham , Kathryn Williams
{"title":"Exploring patient perspectives: Information-seeking behaviours, beliefs and support needs prior to bariatric surgery","authors":"Sally Badorrek , Janet Franklin , Michael Devadas , Nicholas Williams , Rachel Russell , Supreet Saluja , Marijka Batterham , Kathryn Williams","doi":"10.1016/j.orcp.2025.09.002","DOIUrl":"10.1016/j.orcp.2025.09.002","url":null,"abstract":"<div><h3>Aims</h3><div>To explore information-seeking behaviours, influences, expectations, and healthcare professional and psychosocial support needs among individuals preparing for bariatric surgery in New South Wales (NSW), Australia, and to examine differences across public/private and metropolitan/regional healthcare settings.</div></div><div><h3>Methods</h3><div>Baseline data were collected from a longitudinal, prospective cohort study (HREC 2020/ETH02984) using a purpose-designed questionnaire, from April 2021-September 2024. Adults were recruited from four bariatric services (two public, two private) across metropolitan and regional NSW. Outcomes included self-reported demographics, information sources, beliefs, and support needs prior to surgery.</div></div><div><h3>Results</h3><div>Participants (n = 238) were predominantly female (79.0 %), aged 43 ± 11.3 years, with a median BMI of 44.5 kg/m² (IQR 39.4–49.7). Of the cohort, 74.0 % attended private and 66.8 % metropolitan services. Public participants had significantly higher BMI than private (48.3 vs 42.2 kg/m², p < 0.05). Key barriers to weight loss included stress, illness, medications, and limited support, particularly in regional and public groups. Most accessed information from the internet (72.0 %) and GPs (67.0 %), with GP involvement higher in regional (81.7 %) and public (82.5 %) settings. Peer experiences strongly influenced decision-making. Participants expected 33–35 % total weight loss, above typical Australian outcomes (29.0 %), and were motivated by health (94.7 %), quality of life (90.0 %), and activity (81.4 %). Common concerns included weight regain (90.0 %), excess skin (89.0 %), and dietary restrictions (75.0 %). Most (71.8 %) anticipated support for 12 months or less or were unsure.</div></div><div><h3>Conclusion</h3><div>Individuals preparing for bariatric surgery reported high expectations and varied healthcare professional and psychosocial support needs. Differences across settings highlight inequities in access, supporting the need for tailored, multidisciplinary care and realistic goal-setting.</div></div>","PeriodicalId":19408,"journal":{"name":"Obesity research & clinical practice","volume":"19 5","pages":"Pages 409-416"},"PeriodicalIF":2.5,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145058232","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Association between body fat percentage and vitamin D deficiency among Korean adults: A cross-sectional study","authors":"Sunhye Shin , Chan Yoon Park","doi":"10.1016/j.orcp.2025.10.006","DOIUrl":"10.1016/j.orcp.2025.10.006","url":null,"abstract":"<div><div>Vitamin D deficiency is associated with obesity, as vitamin D may be sequestered or diluted in adipose tissue. This cross-sectional study investigated the association between serum 25-hydroxyvitamin D [25(OH)D] levels and body fat percentage in Korean adults from the KNHANES IX. A total of 4176 participants were analyzed and stratified by sex and age. Total, appendicular, and trunk fat mass were assessed using bioelectrical impedance analysis and serum 25(OH)D3 concentrations were measured using LC-MS. Multivariable linear and logistic regression models were employed to investigate the relationship between vitamin D deficiency (< 20 ng/mL) and body fat percentage. After adjusting for age, lifestyle factors, dietary factors, and medical condition, younger adults (19–64y) in the highest quartile of body fat percentage (Q4) had significantly higher odds of vitamin D deficiency (men: OR 1.71; 95 % CI, 1.16−2.52, women: OR 1.71; 95 % CI: 1.26–2.31) compared to those in the lowest quartile (Q1). Similarly, older men (≥65y) in the second and third highest quartiles and older women in the highest quartile showed significantly higher odds. In both age and sex groups, total and appendicular body fat percentages were inversely associated with serum 25(OH)D3 levels (all p < 0.05). Trunk fat percentage was inversely associated with serum 25(OH)D3 levels in younger men and women and in older women (all p < 0.05), but not in older men (p = 0.061). These results indicate that higher body fat percentage partially contributes to vitamin D deficiency across all age and sex groups, with appendicular fat exhibiting a consistent association.</div></div>","PeriodicalId":19408,"journal":{"name":"Obesity research & clinical practice","volume":"19 5","pages":"Pages 441-447"},"PeriodicalIF":2.5,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145398498","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}