{"title":"Recent Progress of Cardiac MRI for Nuclear Medicine Professionals","authors":"Yeon Hyeon Choe, S. Kim","doi":"10.1007/s13139-024-00850-9","DOIUrl":"https://doi.org/10.1007/s13139-024-00850-9","url":null,"abstract":"","PeriodicalId":19384,"journal":{"name":"Nuclear Medicine and Molecular Imaging","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2024-02-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139838295","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Srinivas Ananth Kumar, Harmandeep Singh, L. Kaman, R. Nada, BHAGWANT R. Mittal
{"title":"Annotating the Role of 18F-FDG PET/CT in Fibromatoses: A Benign Masquerader of Malignancies—Is It Really an Advantageous Tool?","authors":"Srinivas Ananth Kumar, Harmandeep Singh, L. Kaman, R. Nada, BHAGWANT R. Mittal","doi":"10.1007/s13139-024-00846-5","DOIUrl":"https://doi.org/10.1007/s13139-024-00846-5","url":null,"abstract":"","PeriodicalId":19384,"journal":{"name":"Nuclear Medicine and Molecular Imaging","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2024-02-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139838648","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Recent Progress of Cardiac MRI for Nuclear Medicine Professionals","authors":"Yeon Hyeon Choe, S. Kim","doi":"10.1007/s13139-024-00850-9","DOIUrl":"https://doi.org/10.1007/s13139-024-00850-9","url":null,"abstract":"","PeriodicalId":19384,"journal":{"name":"Nuclear Medicine and Molecular Imaging","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2024-02-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139778369","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Srinivas Ananth Kumar, Harmandeep Singh, L. Kaman, R. Nada, BHAGWANT R. Mittal
{"title":"Annotating the Role of 18F-FDG PET/CT in Fibromatoses: A Benign Masquerader of Malignancies—Is It Really an Advantageous Tool?","authors":"Srinivas Ananth Kumar, Harmandeep Singh, L. Kaman, R. Nada, BHAGWANT R. Mittal","doi":"10.1007/s13139-024-00846-5","DOIUrl":"https://doi.org/10.1007/s13139-024-00846-5","url":null,"abstract":"","PeriodicalId":19384,"journal":{"name":"Nuclear Medicine and Molecular Imaging","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2024-02-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139779008","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A Review of Machine Learning Approaches for Brain Positron Emission Tomography Data Analysis","authors":"Ke Xu, Hakmook Kang","doi":"10.1007/s13139-024-00845-6","DOIUrl":"https://doi.org/10.1007/s13139-024-00845-6","url":null,"abstract":"","PeriodicalId":19384,"journal":{"name":"Nuclear Medicine and Molecular Imaging","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2024-02-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139858448","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A Review of Machine Learning Approaches for Brain Positron Emission Tomography Data Analysis","authors":"Ke Xu, Hakmook Kang","doi":"10.1007/s13139-024-00845-6","DOIUrl":"https://doi.org/10.1007/s13139-024-00845-6","url":null,"abstract":"","PeriodicalId":19384,"journal":{"name":"Nuclear Medicine and Molecular Imaging","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2024-02-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139798571","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Comparison of SUV<sub>A</sub><sub>/V</sub> and SUV<sub>A</sub><sub>-V</sub> for Evaluating Atherosclerotic Inflammation in <sup>18</sup>F-FDG PET/CT.","authors":"Jeongryul Ryu, Shin Ae Han, Sangwon Han, Sunju Choi, Dae Hyuk Moon, Minyoung Oh","doi":"10.1007/s13139-023-00822-5","DOIUrl":"10.1007/s13139-023-00822-5","url":null,"abstract":"<p><strong>Purpose: </strong>This study aimed to compare the clinical significance of two parameters, division of standardized uptake value (SUV) of target arterial activity by background venous blood pool activity (SUV<sub>A/V</sub>) and subtraction of background venous blood pool activity from SUV of target arterial activity (SUV<sub>A-V</sub>) of carotid arteries with atherosclerotic plaques using <sup>18</sup>F-fluorodeoxyglucose (FDG) positron emission tomography and computed tomography (PET/CT).</p><p><strong>Methods: </strong>Patients aged 50 years or more who were diagnosed with carotid artery stenosis of 50% or more with carotid Doppler ultrasonography and had torso <sup>18</sup>F-FDG PET/CT were enrolled retrospectively and classified patients who developed cerebrovascular events (CVEs) within 5 years after <sup>18</sup>F-FDG PET/CT scan as the active group and patients who did not experience the CVE within 5 years as an inactive group. We calculated SUV<sub>A/V</sub> and SUV<sub>A-V</sub> using measurements of SUV<sub>max</sub> of carotid arteries and mean SUV of superior vena cava (SVC).</p><p><strong>Results: </strong>SUV<sub>A-V</sub>, SUV<sub>A-V_high</sub>, and SUV<sub>A-V_low</sub> were significantly higher in the active group than in the inactive group, but neither SUV<sub>A/V</sub>, SUV<sub>A/V_high</sub>, nor SUV<sub>A/V_low</sub> showed significant differences between the active and inactive groups. The difference in rank between groups of SUV<sub>A/V_high</sub> and SUV<sub>A/V_low</sub> was greater than the difference in rank between groups of SUV<sub>A-V_high</sub> and SUV<sub>A-V_low</sub>. The CVE incidence differed between SUV<sub>A/V_high</sub> and SUV<sub>A/V_low</sub> of high carotid FDG uptake, but the CVE incidence did not differ between SUV<sub>A-V_high</sub> and SUV<sub>A-V_low</sub> of high carotid FDG uptake.</p><p><strong>Conclusion: </strong>SUV<sub>A-V</sub> may be a more rational solution than SUV<sub>A/V</sub> for evaluating atherosclerotic plaque inflammation on <sup>18</sup>F-FDG PET/CT.</p>","PeriodicalId":19384,"journal":{"name":"Nuclear Medicine and Molecular Imaging","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10796899/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41560193","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Virginia Liberini, Simona Peano, Emanuele Fabbro, Riccardo Laudicella, Alberto Papaleo, Michele Balma
{"title":"[<sup>11</sup>C]Choline PET/CT in a Patient with Prostate Cancer Biochemical Recurrence Showing Two Suspicious Findings in the Breast and Liver.","authors":"Virginia Liberini, Simona Peano, Emanuele Fabbro, Riccardo Laudicella, Alberto Papaleo, Michele Balma","doi":"10.1007/s13139-023-00817-2","DOIUrl":"10.1007/s13139-023-00817-2","url":null,"abstract":"<p><p>A 79-year-old man with prostate cancer (PCa) was referred to our center to perform a [<sup>11</sup>C]Choline PET/CT for biochemical recurrence. Positron emission tomography/computed tomography (PET/CT) scan detected PCa recurrence in the prostate gland and several pelvic and abdominal lymph nodes. Two abnormal uptakes were also identified in the right breast and in the liver, respectively. Breast histological findings turned out to be gynecomastia, while the liver lesion resulted in a benign perfusion anomaly at follow-up magnetic resonance imaging (MRI). Although incidental findings were benign in this case, it is important to always investigate abnormal uptakes of [<sup>11</sup>C]Choline, as it could be an expression of further metastases or synchronous malignancies such as breast cancer and hepatocellular carcinoma.</p>","PeriodicalId":19384,"journal":{"name":"Nuclear Medicine and Molecular Imaging","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10796308/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41498932","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yusuke Kawasaki, Junichi Tsuchiya, Akihisa Tasaki, Ukihide Tateishi, Kota Yokoyama
{"title":"[<sup>18</sup>F]FDG PET/CT Findings of Mass-Forming Actinomycosis in an Uncontrolled Diabetic Patient.","authors":"Yusuke Kawasaki, Junichi Tsuchiya, Akihisa Tasaki, Ukihide Tateishi, Kota Yokoyama","doi":"10.1007/s13139-023-00815-4","DOIUrl":"10.1007/s13139-023-00815-4","url":null,"abstract":"<p><p>We report a case of cervicofacial actinomycosis mimicking malignant sarcoma in a 78-year-old man with diabetes. High lesion uptake and decreased cerebral uptake on [<sup>18</sup>F]FDG PET/CT provide a potentially important diagnostic clue suggesting infectious disease in a poorly controlled diabetic patient.</p>","PeriodicalId":19384,"journal":{"name":"Nuclear Medicine and Molecular Imaging","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10796864/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45454854","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sanjana Ballal, Madhav P Yadav, Shobhana Raju, Frank Roesch, Marcel Martin, Madhavi Tripathi, Chandrasekhar Bal
{"title":"[<sup>177</sup>Lu]Lu-DOTAGA.Glu.(FAPi)<sub>2</sub> Radionuclide Therapy: a New Treatment Option for Patients with Glioblastoma Multiforme.","authors":"Sanjana Ballal, Madhav P Yadav, Shobhana Raju, Frank Roesch, Marcel Martin, Madhavi Tripathi, Chandrasekhar Bal","doi":"10.1007/s13139-023-00814-5","DOIUrl":"10.1007/s13139-023-00814-5","url":null,"abstract":"<p><p>In this case report, we present the clinical management of a 52-year-old female patient with a recurrent right temporo-parietal glioblastoma multiforme (GBM). The patient presented with symptoms of headache and loss of balance and recurrence on magnetic resonance imaging (MRI). To evaluate the fibroblast activation protein inhibitor (FAPi) expression in the recurrent lesion, an exploratory [<sup>68</sup> Ga]Ga-DOTA.SA.FAPi PET/CT scan was performed. The imaging results revealed FAPi expression in the lesion located in the right temporo-parietal region. Based on the findings of FAPi expression, the patient underwent [<sup>177</sup>Lu]Lu-DOTAGA.Glu.(FAPi)<sub>2</sub> treatment. After completing two cycles of [<sup>177</sup>Lu]Lu-DOTAGA.Glu.(FAPi)<sub>2</sub> therapy, a follow-up [<sup>68</sup> Ga]Ga-DOTA.SA.FAPi PET/CT scan was conducted. The post-treatment imaging showed a significant reduction in FAPi uptake and regression in the size of the lesion, as well as a decrease in perilesional edema, as observed on the MRI. Furthermore, the patient experienced an improvement in symptoms and performance status. These results suggest that [<sup>68</sup> Ga]Ga-DOTA.SA.FAPi monomer imaging and [<sup>177</sup>Lu]Lu-DOTAGA.Glu.(FAPi)<sub>2</sub> dimer therapeutics hold promise for patients with recurrent GBM when other standard-line therapeutic options have been exhausted. This case highlights the potential of using FAPi-based theranostics in the management of recurrent GBM, providing a potential avenue for personalized treatment in patients who have limited treatment options available.</p>","PeriodicalId":19384,"journal":{"name":"Nuclear Medicine and Molecular Imaging","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10796854/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45336979","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}