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Nouvelle revue francaise d'hematologie最新文献

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Multiple myeloma with bone marrow biopsy features simulating concomitant chronic idiopathic myelofibrosis. 多发性骨髓瘤伴伴慢性特发性骨髓纤维化。
Nouvelle revue francaise d'hematologie Pub Date : 1995-01-01
U Schmidt, M Ruwe, L D Leder
{"title":"Multiple myeloma with bone marrow biopsy features simulating concomitant chronic idiopathic myelofibrosis.","authors":"U Schmidt,&nbsp;M Ruwe,&nbsp;L D Leder","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Multiple myelomas occasionally exhibit bone marrow lesions simulating a concomitant chronic idiopathic myelofibrosis. In the present study, trephine biopsy histologies of such \"myelofibrotic\" myelomas are described and compared to those from a case of true chronic idiopathic myelofibrosis which developed in the course of chronic lymphocytic leukaemia. \"Myelofibrotic\" myeloma are characterized by osteosclerosis, marrow fibrosis and focal megakaryocytic hyperplasia in the presence of plasma cell infiltration of the bone marrow. These myelomas are to be distinguished from the more commonly occurring multiple myeloma with simple marrow fibrosis and/or osteosclerosis. Furthermore, \"myelofibrotic\" myelomas are not identical to myelomas coexisting with true chronic idiopathic myelofibrosis, a condition which would appear to be extremely rare and should only be diagnosed if focal megakaryocytic hyperplasia with atypia can be unequivocally demonstrated. Avoidance of misinterpretation of \"myelofibrotic\" myeloma requires a knowledge of these different myeloma variants.</p>","PeriodicalId":19366,"journal":{"name":"Nouvelle revue francaise d'hematologie","volume":"37 2","pages":"159-63"},"PeriodicalIF":0.0,"publicationDate":"1995-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18647700","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Naftazone accelerates human saphenous vein endothelial cell proliferation in vitro. 纳夫他酮促进人隐静脉内皮细胞体外增殖。
Nouvelle revue francaise d'hematologie Pub Date : 1995-01-01
C Klein-Soyer, C Bloy, G Archipoff, A Beretz, J P Cazenave
{"title":"Naftazone accelerates human saphenous vein endothelial cell proliferation in vitro.","authors":"C Klein-Soyer,&nbsp;C Bloy,&nbsp;G Archipoff,&nbsp;A Beretz,&nbsp;J P Cazenave","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Restoration of a haemocompatible surface after endothelial damage induced by treatments such as embolectomy, angioplasty, endarterectomy or irradiation or following vascular graft implantation is an important factor for the ultimate success of these interventions. The development of substances which enhance endothelial cell growth and accelerate their proliferation is therefore of great interest in such situations. In the present work naftazone was shown to accelerate human saphenous vein endothelial cell proliferation in vitro at concentrations which did not alter the hemostatic balance, resulting in a cell density at confluence 20% higher than in controls. This compound was able to partially substitute for serum requirements and further displayed additive effects in the presence of fibroblast growth factors. Thus naftazone, an original synthetic molecule distinct from growth factor peptides, is a promising candidate drug for the amelioration of vascular repair.</p>","PeriodicalId":19366,"journal":{"name":"Nouvelle revue francaise d'hematologie","volume":"37 3","pages":"187-92"},"PeriodicalIF":0.0,"publicationDate":"1995-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18573033","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Infrequent sites of extramedullary relapse after allogeneic bone marrow transplantation. 异基因骨髓移植后髓外复发的罕见部位。
Nouvelle revue francaise d'hematologie Pub Date : 1995-01-01
F Viard, C Bilhou-Nabera, G Marit, F Durrieu, P Dubus, T Masseron, J M Boiron, M J Gharbi, S Salzes, A Broustet
{"title":"Infrequent sites of extramedullary relapse after allogeneic bone marrow transplantation.","authors":"F Viard,&nbsp;C Bilhou-Nabera,&nbsp;G Marit,&nbsp;F Durrieu,&nbsp;P Dubus,&nbsp;T Masseron,&nbsp;J M Boiron,&nbsp;M J Gharbi,&nbsp;S Salzes,&nbsp;A Broustet","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>In the present report, we describe two cases of rare extramedullary relapse (skin, muscle) after allogeneic bone marrow transplantation (BMT). As both patients were male and had received sex mismatched (non T-depleted) BMT, marrow samples were analysed with a Y-chromosome specific probe allowing the sensitive detection of host DNA. The proportion of host DNA remained low in all post BMT samples from these patients, even at the time of extramedullary relapse.</p>","PeriodicalId":19366,"journal":{"name":"Nouvelle revue francaise d'hematologie","volume":"37 2","pages":"153-7"},"PeriodicalIF":0.0,"publicationDate":"1995-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18647699","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The frequency of the factor V gene R506Q mutation varies between regions of France. 因子V基因R506Q突变的频率在法国不同地区有所不同。
Nouvelle revue francaise d'hematologie Pub Date : 1995-01-01
F Soubrier, I Fery, E Verdy, M N René, B Varsat, S Visvikis, G Siest
{"title":"The frequency of the factor V gene R506Q mutation varies between regions of France.","authors":"F Soubrier,&nbsp;I Fery,&nbsp;E Verdy,&nbsp;M N René,&nbsp;B Varsat,&nbsp;S Visvikis,&nbsp;G Siest","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":19366,"journal":{"name":"Nouvelle revue francaise d'hematologie","volume":"37 2","pages":"175"},"PeriodicalIF":0.0,"publicationDate":"1995-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18647702","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Erythropoietin and delayed taking of autologous blood: from physiologic secretion to the rationale for exogenous supplementation]. [促红细胞生成素与延迟服用自体血:从生理性分泌到外源性补充的基本原理]。
Nouvelle revue francaise d'hematologie Pub Date : 1995-01-01
N Casadevall
{"title":"[Erythropoietin and delayed taking of autologous blood: from physiologic secretion to the rationale for exogenous supplementation].","authors":"N Casadevall","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":19366,"journal":{"name":"Nouvelle revue francaise d'hematologie","volume":"37 Suppl 1 ","pages":"S11-5"},"PeriodicalIF":0.0,"publicationDate":"1995-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18489195","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Delayed taking of autologous blood in 1995]. [1995年延迟采自体血]。
Nouvelle revue francaise d'hematologie Pub Date : 1995-01-01
J Baudelot
{"title":"[Delayed taking of autologous blood in 1995].","authors":"J Baudelot","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":19366,"journal":{"name":"Nouvelle revue francaise d'hematologie","volume":"37 Suppl 1 ","pages":"S9-10"},"PeriodicalIF":0.0,"publicationDate":"1995-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18489200","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Localized stage non-Hodgkin's lymphoma of the testis: a retrospective study of 16 cases. 睾丸局部分期非霍奇金淋巴瘤16例回顾性分析。
Nouvelle revue francaise d'hematologie Pub Date : 1995-01-01
M Ostronoff, C Soussain, E Zambon, A Moran, J P Droz, J Bosq, C Bayle, J M Cosset, M Hayat
{"title":"Localized stage non-Hodgkin's lymphoma of the testis: a retrospective study of 16 cases.","authors":"M Ostronoff,&nbsp;C Soussain,&nbsp;E Zambon,&nbsp;A Moran,&nbsp;J P Droz,&nbsp;J Bosq,&nbsp;C Bayle,&nbsp;J M Cosset,&nbsp;M Hayat","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The present report concerns a retrospective study of 16 patients with localized intermediate- or high-grade non-Hodgkin's lymphoma of the testis treated in one institution from 1973 to 1990. Ann Arbor stage of disease was IE in 11 and IIE in 5 cases. All except one patient underwent initial inguinal orchidectomy, 11 were disease free after surgery and 12 received inverted Y radiation therapy. All patients achieved a complete remission (CR). Relapse occurred in 8 of 9 patients who did not receive initial chemotherapy, but in only 3 of 7 patients initially treated with chemotherapy including anthracyclins. In 3 cases relapse was confined to the CNS, while diffuse relapse in 8 others included 4 cases of CNS involvement. Eight patients are now alive in CR (5 in first CR, 1 in second CR and 2 in third CR) with a median follow-up of 68.5 months (range 54-101). Chemotherapy thus emerges as the initial treatment of preference for localized testicular lymphoma. Therapy should be preceded by a thorough assessment of the stage of disease and due to the high frequency of CNS relapse, CNS prophylaxis should be considered for all patients.</p>","PeriodicalId":19366,"journal":{"name":"Nouvelle revue francaise d'hematologie","volume":"37 5","pages":"267-72"},"PeriodicalIF":0.0,"publicationDate":"1995-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19674838","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Allogeneic transplantation of peripheral blood progenitor cells. 外周血祖细胞异体移植。
Nouvelle revue francaise d'hematologie Pub Date : 1995-01-01
N Schmitz
{"title":"Allogeneic transplantation of peripheral blood progenitor cells.","authors":"N Schmitz","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Transplantation of autologous peripheral blood progenitor cells (PBPC) is now a well established method to reconstitute haematopoiesis after high-dose chemoradiotherapy. Allogeneic PBPCs have rarely been used as the sole measure to induce haematopoietic recovery after myeloablative therapy because of uncertainties regarding the durability of engraftment and the risk of acute and chronic graft-vs-host disease (GVHD). In addition, this technique requires the exposure of normal donors to granulocyte colony stimulating factor (G-CSF) in order to mobilise a sufficient number of PBPCs which can then be collected by leukapheresis. We report here our initial experience with allogeneic transplantation of PBPCs in order to demonstrate the feasibility and safety of harvesting sufficient numbers of PBPCs in healty donors. In addition, the early results presented in this communication show that allogeneic PBPCs can successfully be used to restore haematopoiesis in HLA-identical siblings of the donor without causing devastating graft-vs-host disease.</p>","PeriodicalId":19366,"journal":{"name":"Nouvelle revue francaise d'hematologie","volume":"37 6","pages":"377-9"},"PeriodicalIF":0.0,"publicationDate":"1995-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19873346","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Intra-abdominal localization of acute leukaemia: report of six cases. 急性白血病腹腔内定位6例报告。
Nouvelle revue francaise d'hematologie Pub Date : 1995-01-01
J E Kurtz, E Andres, F Maloisel, L Voillat, A Brion, F Oberling
{"title":"Intra-abdominal localization of acute leukaemia: report of six cases.","authors":"J E Kurtz,&nbsp;E Andres,&nbsp;F Maloisel,&nbsp;L Voillat,&nbsp;A Brion,&nbsp;F Oberling","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Clinical findings leading to the diagnosis of acute leukaemia result from the consequences of both pancytopenia and tumoral manifestations. Although leukaemic infiltration of hematopoietic organs is common, the involvement of non-hematopoietic abdominal organs remains rare. The authors report a series of six cases, where intra-abdominal localization of acute lymphoblastic or myeloblastic leukaemia was detected at diagnosis or relapse. Chemotherapy may lead to remission or cure if the early abdominal complications are managed with care.</p>","PeriodicalId":19366,"journal":{"name":"Nouvelle revue francaise d'hematologie","volume":"37 5","pages":"273-6"},"PeriodicalIF":0.0,"publicationDate":"1995-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19674839","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Selection and expansion of CD34+ cells. CD34+细胞的选择和扩增。
Nouvelle revue francaise d'hematologie Pub Date : 1995-01-01
I K McNiece
{"title":"Selection and expansion of CD34+ cells.","authors":"I K McNiece","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":19366,"journal":{"name":"Nouvelle revue francaise d'hematologie","volume":"37 6","pages":"375-6"},"PeriodicalIF":0.0,"publicationDate":"1995-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19873345","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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