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Safety and Efficacy of Balloon-Assisted Kyphoplasty Followed by Stereotactic Body Radiation Therapy for Pathological Fractures. 球囊辅助椎体后凸成形术后立体定向体放射治疗病理性骨折的安全性和有效性
IF 3.9 2区 医学
Neurosurgery Pub Date : 2025-04-01 Epub Date: 2024-09-16 DOI: 10.1227/neu.0000000000003182
Samuel Adida, Michael R Kann, Suchet Taori, Shovan Bhatia, Roberta K Sefcik, Steven A Burton, John C Flickinger, Peter C Gerszten
{"title":"Safety and Efficacy of Balloon-Assisted Kyphoplasty Followed by Stereotactic Body Radiation Therapy for Pathological Fractures.","authors":"Samuel Adida, Michael R Kann, Suchet Taori, Shovan Bhatia, Roberta K Sefcik, Steven A Burton, John C Flickinger, Peter C Gerszten","doi":"10.1227/neu.0000000000003182","DOIUrl":"10.1227/neu.0000000000003182","url":null,"abstract":"<p><strong>Background and objectives: </strong>In patients experiencing pain secondary to pathological compression fractures, balloon-assisted kyphoplasty and subsequent stereotactic body radiation therapy (SBRT) may allow for restoration of vertebral height and irradiation of the underlying malignancy to control local disease progression. The aim of this study was to evaluate the safety and efficacy of kyphoplasty treatment before SBRT in patients with spinal metastases and benign tumors.</p><p><strong>Methods: </strong>An analysis of a prospectively collected database of 70 patients and 75 metastatic and benign spinal lesions that underwent kyphoplasty before SBRT at a single institution (2002-2023) was conducted. Patient characteristics were recorded, including treatment history, dosimetry and fractionation schedule, pain outcomes, local control (LC), and overall survival. The Bilsky score and Spinal Instability Neoplastic Score were calculated to assess epidural involvement and spinal stability, respectively.</p><p><strong>Results: </strong>The median time from kyphoplasty to SBRT was 29 days (range: 2-159). Seventy-two lesions (96%) were managed with single-fraction SBRT and 3 lesions (4%) with a multifraction regimen. The median single-fraction prescription dose was 20 Gy (range: 12-25) delivered to a median tumor volume of 35.1 cc (range: 2.2-160). After a median follow-up period of 9 months (range: 1-201), 6 lesions (8%) locally progressed. Pain was reported to improve or remain stable for most patients (88%). The LC rate was 88% at 6 months, 1 year, and 2 years. No prognostic factors were significantly associated with LC. The median overall survival was 11 months (range: 1-201) after radiosurgery. There were no reports of cement extravasation or radiation-induced neurological deficit. Two acute pain flares (3%) were reported 1 and 3 months after radiosurgery.</p><p><strong>Conclusion: </strong>The combined kyphoplasty and SBRT treatment paradigm can be used to treat patients with painful pathological compression fractures. Long-term LC and patient-reported improvement in pain were observed without the morbidity associated with open surgery.</p>","PeriodicalId":19276,"journal":{"name":"Neurosurgery","volume":" ","pages":"860-869"},"PeriodicalIF":3.9,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142292276","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Epilepsy Surgery for Drug-Resistant Epilepsy in Africa: A Systematic Review. 非洲耐药癫痫的手术治疗:系统综述。
IF 3.9 2区 医学
Neurosurgery Pub Date : 2025-04-01 Epub Date: 2024-12-12 DOI: 10.1227/neu.0000000000003307
Kwadwo Darko, Pearl Ohenewaa Tenkorang, Olivia Asiedu, W Elorm Yevudza, Salim Issah, Eyako Dzantor, Marjidah Tahiru, Andrew Awuah Wireko, Sean O'Leary, Umaru Barrie, Hannah Weiss, Teddy Totimeh, Mabel Banson
{"title":"Epilepsy Surgery for Drug-Resistant Epilepsy in Africa: A Systematic Review.","authors":"Kwadwo Darko, Pearl Ohenewaa Tenkorang, Olivia Asiedu, W Elorm Yevudza, Salim Issah, Eyako Dzantor, Marjidah Tahiru, Andrew Awuah Wireko, Sean O'Leary, Umaru Barrie, Hannah Weiss, Teddy Totimeh, Mabel Banson","doi":"10.1227/neu.0000000000003307","DOIUrl":"10.1227/neu.0000000000003307","url":null,"abstract":"<p><strong>Background and objectives: </strong>Nearly one-third of individuals with epilepsy have drug-resistant epilepsy, treated most effectively with surgery. This study aims to discuss the demographic profile, surgical access, and strategies used in drug-resistant epilepsy in Africa.</p><p><strong>Methods: </strong>A systematic review was performed using PubMed, Google Scholar, Embase, and Web of Science in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-analyses guidelines.</p><p><strong>Results: </strong>Nine studies encompassing 498 patients from 6 African countries (Egypt, Kenya, Morocco, South Africa, Tunisia, and Uganda) were included. The mean Methodological Index for Non-Randomized Studies score for these articles was 9.6 ± 1.6. The average patient age was 24.9 years (95% CI: 18.9-30.8 years), with a male predominance of 53.4%. The average age of seizure onset was 10.4 years (95% CI: 6.1-14.7 years). Most patients experienced focal onset seizures (73.1%), with head trauma (33.1%) being the most reported risk factor. The predominant etiologies were hippocampal sclerosis (66.8%, 95% CI: 42.7-91), microdysgenesis (26.7%, 95% CI: 20.7-32.7), and brain tumors (22.3%, 95% CI: 6.4-38.2). Lesions were primarily located in the left hemisphere (61.9%, 95% CI: 26.7-97.1), with temporal lobe involvement in 54.8% of cases (95% CI: 28.7-80.8). Temporal lobectomy was the most frequently performed surgery (59.6%), followed by lesionectomy (9.6%). Postoperatively, 80.6% of patients achieved Engel class I outcomes, indicating seizure freedom, and long-term follow-up (1 to 5 years) showed that 70.3% maintained Engel class I outcomes. Surgical complications were reported in 8.8% of cases.</p><p><strong>Conclusion: </strong>These findings demonstrate the efficacy and long-term benefits of epilepsy surgery in Africa, where epilepsy is a significant public health challenge. The high rates of seizure freedom and reduced seizure frequency from surgery highlight its potential to improve the quality of life for individuals with drug-resistant epilepsy in Africa.</p>","PeriodicalId":19276,"journal":{"name":"Neurosurgery","volume":" ","pages":"704-712"},"PeriodicalIF":3.9,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142813838","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Barriers to Care: Examining the Unique Obstacles of Indigenous American Patients With Acute Neurosurgical Injuries. 护理障碍:检查急性神经外科损伤的美洲原住民患者的独特障碍。
IF 3.9 2区 医学
Neurosurgery Pub Date : 2025-04-01 Epub Date: 2024-09-20 DOI: 10.1227/neu.0000000000003162
Kyril L Cole, Samuel A Tenhoeve, Majid Khan, Matthew C Findlay, Janet Cortez, Ramesh Grandhi, Sarah T Menacho
{"title":"Barriers to Care: Examining the Unique Obstacles of Indigenous American Patients With Acute Neurosurgical Injuries.","authors":"Kyril L Cole, Samuel A Tenhoeve, Majid Khan, Matthew C Findlay, Janet Cortez, Ramesh Grandhi, Sarah T Menacho","doi":"10.1227/neu.0000000000003162","DOIUrl":"10.1227/neu.0000000000003162","url":null,"abstract":"<p><strong>Background and objectives: </strong>Historically, Indigenous American (IA) populations have faced barriers to adequate health care. Although IA people experience higher rates of traumatic brain injury-related mortality than other racial groups in the United States, attributes of their neurosurgical care have not been evaluated. We demonstrate and compare care patterns and outcomes in IA and non-IA adults with acute neurosurgical injuries and identify disparities limiting access to medical care.</p><p><strong>Methods: </strong>Adults hospitalized for acute neurosurgical injuries between 2017 and 2022 were identified in this retrospective cross-sectional study at our Level 1 trauma center. We evaluated demographics, distance to care, and in-hospital/aftercare characteristics in a propensity-matched analysis.</p><p><strong>Results: </strong>A total of 81 IA patients were identified. Propensity score analysis matched 77 IA and 77 non-IA patients with similar inclusion criteria on demographics, medical comorbidities, and distance traveled to neurosurgical care. IA patients traveled longer distances for care (236.3 vs 146.4 miles, P < .001), were more often direct admissions (35.1% vs 0.0%), were more often transported via ambulance (72.7% vs 57.1%) and less often via helicopter (20.8% vs 41.6%), and came from a broader cross-section of states. Average time from injury to care was 6 hours (IQR 3.0, 9.4). In-hospital care did not differ between groups; however, IA patients were less often discharged to rehabilitation (2.6% vs 14.3%, P = .009). IA in-hospital traumatic brain injury-related mortality was 8.3%. Fewer follow-up visits were completed in IA than in non-IA patients (40.2% vs 90.0%, P < .001), despite more attempted contacts (66.7% vs 30.6%, P < .001), with low telemedicine use in both groups (2.7% vs 5.5%). IA status and distance traveled were independent predictors of unmet follow-up visits (odds ratio 6.22 [95% CI 1.49-25.99, P = .012] and odds ratio 12.34 [95% CI 1.19-127.99, P = .035], respectively).</p><p><strong>Conclusion: </strong>Clear barriers to care were demonstrated for IA patients with acute neurosurgical injuries. Our findings indicate improvements are needed for this vulnerable population.</p>","PeriodicalId":19276,"journal":{"name":"Neurosurgery","volume":" ","pages":"841-849"},"PeriodicalIF":3.9,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142984243","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Clinical Outcomes and Radiographic Results of Prone Transpsoas Lateral Lumbar Interbody Fusion: A Single-Institution Case Series. 俯卧位经腰椎侧路腰椎椎间融合术的临床效果和影像学结果:单机构病例系列。
IF 3.9 2区 医学
Neurosurgery Pub Date : 2025-04-01 Epub Date: 2024-09-06 DOI: 10.1227/neu.0000000000003151
Jeff Ehresman, S Harrison Farber, Madison Battista, Katriel E Lee, Bryan S Lee
{"title":"Clinical Outcomes and Radiographic Results of Prone Transpsoas Lateral Lumbar Interbody Fusion: A Single-Institution Case Series.","authors":"Jeff Ehresman, S Harrison Farber, Madison Battista, Katriel E Lee, Bryan S Lee","doi":"10.1227/neu.0000000000003151","DOIUrl":"10.1227/neu.0000000000003151","url":null,"abstract":"<p><strong>Background and objectives: </strong>This study assessed feasibility, radiologic parameters, and clinical outcomes in patients who underwent the prone transpsoas (PTP) approach for lateral lumbar interbody fusion.</p><p><strong>Methods: </strong>This retrospective observational study included consecutive patients who underwent PTP performed by a single surgeon. Data were collected including age, sex, body mass index, operative levels, retraction time, complications, radiographic measurements, and visual analog scale pain scores. Statistical analyses were performed using nonparametric Wilcoxon 2-sample tests.</p><p><strong>Results: </strong>A total of 106 consecutive patients (mean [SD] age, 66 [15] years; mean [SD] body mass index, 29.3 [5.0]) underwent PTP on 173 spinal levels, with a mean (SD) follow-up of 13 (8) months. Sixty of 106 (57%) patients underwent a 1-level PTP procedure (range, 1-4 levels), most commonly on L4-5. The mean (SD) retraction time was 10.4 (3.1) minutes for L1-2, 9.7 (2.8) minutes for L2-3, 9.3 (2.3) minutes for L3-4, and 9.5 (3.2) minutes for L4-5. Adverse events included incidental anterior longitudinal ligament release (3 of 173 [2%] levels) and transient ipsilateral hip flexor weakness (1 of 106 [0.9%] patients). The mean pelvic incidence was 57°. Lumbar lordosis increased from a mean of 44° to 51° ( P < .001). Pelvic tilt decreased from a mean of 20° to 12° ( P < .001). Pelvic incidence-lumbar lordosis mismatch decreased from a mean of 13 to 5 ( P < .001). Visual analog scale pain scores improved from a mean of 6 preoperatively to 5 postoperatively ( P < .001).</p><p><strong>Conclusion: </strong>In this single-institution patient series, the PTP approach was effective and safe for lateral lumbar fusion, with minimal complications and improved lumbar lordosis and patient-reported pain outcomes.</p>","PeriodicalId":19276,"journal":{"name":"Neurosurgery","volume":" ","pages":"763-768"},"PeriodicalIF":3.9,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142140664","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Vertebrobasilar Artery Occlusion Treatment Outcomes Within 24 hours of Estimated Occlusion Time. 估计闭塞时间 24 小时内的椎基底动脉闭塞治疗结果。
IF 3.9 2区 医学
Neurosurgery Pub Date : 2025-04-01 Epub Date: 2024-09-09 DOI: 10.1227/neu.0000000000003160
Yingjie Xu, Pan Zhang, Miaomiao Hu, Wen Sun, Guoqiang Xu, Chunyan Dai
{"title":"Vertebrobasilar Artery Occlusion Treatment Outcomes Within 24 hours of Estimated Occlusion Time.","authors":"Yingjie Xu, Pan Zhang, Miaomiao Hu, Wen Sun, Guoqiang Xu, Chunyan Dai","doi":"10.1227/neu.0000000000003160","DOIUrl":"10.1227/neu.0000000000003160","url":null,"abstract":"<p><strong>Background and objectives: </strong>The aim of this study was to investigate the efficacy and safety of endovascular treatment (EVT) in patients with acute vertebrobasilar artery occlusion (VBAO) within 24 hours of estimated occlusion time (EOT) and to evaluate the effect of early and late time window in a cohort of patients with VBAO treated with EVT.</p><p><strong>Methods: </strong>Retrospective analysis was conducted on patients within 24 hours of the EOT in 65 stroke centers in China. Favorable outcome was defined as modified Rankin Scale ≤3 at 90 days. Patients were divided into the medical management (MM) group and the EVT group. Times were dichotomized into early (EOT ≤6 hours) and late (>6 hours) time windows. Multivariate logical regression models were used to evaluate the efficacy and safety of EVT and the effect of time windows on outcomes in EVT patients.</p><p><strong>Results: </strong>Among 4124 patients, 2473 and 1651 patients were included in the early and late windows, respectively. 1702 patients received MM and 2422 were treated with EVT. EVT was associated with a higher rate of a favorable outcome at 90 days both in early (odds ratio [OR] 2.16, 95% CI 1.94-2.41) and late (OR 1.89, 95% CI 1.65-2.17) time windows. No differences were found regarding favorable outcome (OR 0.95, 95% CI 0.87-1.03) between VBAO patients treated with EVT within and beyond 6 hours.</p><p><strong>Conclusion: </strong>Patients with acute VBAO who received EVT within 24 hours were associated with improved favorable outcome compared with patients who received MM. EVT beyond 6 hours is feasible and safe with no increase in symptomatic intracranial hemorrhage.</p>","PeriodicalId":19276,"journal":{"name":"Neurosurgery","volume":" ","pages":"779-786"},"PeriodicalIF":3.9,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142154706","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Traumatic Vertebral Artery Injury After Subaxial Cervical Spine Injuries: Incidence, Risk Factors, and Long-Term Outcomes: A Population-Based Cohort Study. 颈椎亚轴损伤后外伤性椎动脉损伤:发病率、危险因素和长期结果:一项基于人群的队列研究。
IF 3.9 2区 医学
Neurosurgery Pub Date : 2025-04-01 Epub Date: 2024-09-20 DOI: 10.1227/neu.0000000000003173
Victor Gabriel El-Hajj, Karl J Habashy, Paulina Cewe, Elias Atallah, Aman Singh, Alexander Fletcher-Sandersjöö, Mohamad Bydon, Michael Fagerlund, Pascal Jabbour, Paul Gerdhem, Adrian Elmi-Terander, Erik Edström
{"title":"Traumatic Vertebral Artery Injury After Subaxial Cervical Spine Injuries: Incidence, Risk Factors, and Long-Term Outcomes: A Population-Based Cohort Study.","authors":"Victor Gabriel El-Hajj, Karl J Habashy, Paulina Cewe, Elias Atallah, Aman Singh, Alexander Fletcher-Sandersjöö, Mohamad Bydon, Michael Fagerlund, Pascal Jabbour, Paul Gerdhem, Adrian Elmi-Terander, Erik Edström","doi":"10.1227/neu.0000000000003173","DOIUrl":"10.1227/neu.0000000000003173","url":null,"abstract":"<p><strong>Background and objectives: </strong>Vertebral artery injury (VAI) because of traumatic subaxial cervical spine injury is a rare but potentially devastating condition as it could lead to stroke. The aim of this study was to examine the incidence, risk factors, outcomes, and radiographic predictors of VAI in patients surgically treated for subaxial cervical spine injuries at a tertiary care trauma center.</p><p><strong>Methods: </strong>This is a retrospective population-based cohort study, including all patients surgically treated for traumatic subaxial cervical spine injuries at the study center between 2006 and 2018. Primary outcomes included mortality and morbidity after the injury. Propensity score matching, survival, univariable, and multivariable analyses were used to study the outcomes of interest.</p><p><strong>Results: </strong>Traumatic VAI primarily occurred after high-energy traumas such as motor vehicle accidents and falls from heights. The median age was 64.4 years (47.4-69.1), and 69% were male. In the cohort of patients with subaxial cervical injury, 54% had a spinal cord injury (SCI). In the subgroup with VAI, the frequency of SCI was 66% and a concomitant SCI and VAI were associated with a more severe American Spinal Cord Injury Association Impairment Scale grade ( P = .015). However, after accounting for age, sex, and associated injuries, VAI did not affect postoperative complications, short- or long-term outcomes, or mortality rates. Facet joint dislocation was a unique radiographic predictor of VAI (odds ratio 3.8 [CI 1.42-10.7], P = .009).</p><p><strong>Conclusion: </strong>The findings suggest that clinical outcomes of patients with traumatic cervical spine injuries were not negatively affected by the presence of a VAI. Several radiographic factors were associated with VAI; however, only facet joint dislocation remained as an independent predictor of this injury.</p>","PeriodicalId":19276,"journal":{"name":"Neurosurgery","volume":" ","pages":"881-891"},"PeriodicalIF":3.9,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142984187","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Presidential Address to the 2024 Annual Meeting of the Congress of Neurological Surgeons.
IF 3.9 2区 医学
Neurosurgery Pub Date : 2025-04-01 Epub Date: 2025-03-14 DOI: 10.1227/neu.0000000000003376
Alexander A Khalessi
{"title":"Presidential Address to the 2024 Annual Meeting of the Congress of Neurological Surgeons.","authors":"Alexander A Khalessi","doi":"10.1227/neu.0000000000003376","DOIUrl":"https://doi.org/10.1227/neu.0000000000003376","url":null,"abstract":"","PeriodicalId":19276,"journal":{"name":"Neurosurgery","volume":"71 Supplement_1","pages":"1-5"},"PeriodicalIF":3.9,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143625514","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Increased Traumatic Brain Injury Severity and Mortality in Undocumented Immigrants. 无证移民脑外伤严重程度和死亡率增加。
IF 3.9 2区 医学
Neurosurgery Pub Date : 2025-04-01 Epub Date: 2024-08-30 DOI: 10.1227/neu.0000000000003158
Alexander Tenorio, Michael G Brandel, Carson P McCann, Marcos Real, Jay J Doucet, Todd W Costantini, David R Santiago-Dieppa, Michael Levy, Joseph D Ciacci
{"title":"Increased Traumatic Brain Injury Severity and Mortality in Undocumented Immigrants.","authors":"Alexander Tenorio, Michael G Brandel, Carson P McCann, Marcos Real, Jay J Doucet, Todd W Costantini, David R Santiago-Dieppa, Michael Levy, Joseph D Ciacci","doi":"10.1227/neu.0000000000003158","DOIUrl":"10.1227/neu.0000000000003158","url":null,"abstract":"<p><strong>Background and objectives: </strong>Health disparities related to traumatic brain injury (TBI) have focused on socioeconomic status, race, and ethnicity. We sought to characterize TBI patterns and outcomes based on undocumented status.</p><p><strong>Methods: </strong>Patients who presented to University of California, San Diego Health Trauma Center with a TBI between 2019 and 2022 were identified and stratified based on undocumented status. Undocumented immigrants were identified using validated methods of absent or invalid social security number and key terms through chart review. Demographic information, injury characteristics, and neurosurgical interventions were recorded. Univariable and multivariable analyses were performed to determine the impact of patient factors on outcomes.</p><p><strong>Results: </strong>Of 1654 patients with TBI, 76 (4.6%) were undocumented. Undocumented immigrants were younger (50 vs 60 years; P < .001) and had higher Injury Severity Score (17 vs 13; P < .001). They presented from farther distances (12.8 vs 5.3 miles, P < .001) with greater midline shift (1.49 vs 0.91 mm; P = .003). A greater proportion had basal cistern compression/effacement (14% vs 4.6%; P = .001) and required neurosurgical intervention (18% vs 9.6%; P = .012). Undocumented immigrants had higher hospital charges ($208 403 vs $128 948; P < .001), length of stay (5 vs 4 days; P = .002), and were discharged to a health facility at a lower rate (18% vs 32%; P = .012). They had nearly double the mortality rate (14% vs 7.3%; P = .021), with undocumented status trending as a predictor on multivariable regression (odds ratio = 2.87; P = .052).</p><p><strong>Conclusion: </strong>Undocumented immigrants presented from farther distances with increased TBI severity, likely from both more severe trauma and delayed presentation, requiring more neurosurgical intervention. They also had greater length of stay, charges, and nearly double the mortality rate. Importantly, undocumented status was a strong predictor for mortality. Despite worse outcomes, they were discharged to a health care facility at a lower rate. Advocacy efforts should be directed at increasing health care coverage and migrant community engagement and education.</p>","PeriodicalId":19276,"journal":{"name":"Neurosurgery","volume":" ","pages":"802-810"},"PeriodicalIF":3.9,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142110013","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Laparoscopic-Assisted Peritoneal Access in Ventriculoperitoneal Shunt Placement: Systematic Review and Meta-Analysis. 腹腔镜辅助腹膜入路在脑室腹腔分流术中的应用:系统回顾与元分析》。
IF 3.9 2区 医学
Neurosurgery Pub Date : 2025-04-01 Epub Date: 2024-10-28 DOI: 10.1227/neu.0000000000003213
Sunny Abdelmageed, Prottusha Sarkar, Nathan A Shlobin, Daniel G Davila, Matthew B Potts
{"title":"Laparoscopic-Assisted Peritoneal Access in Ventriculoperitoneal Shunt Placement: Systematic Review and Meta-Analysis.","authors":"Sunny Abdelmageed, Prottusha Sarkar, Nathan A Shlobin, Daniel G Davila, Matthew B Potts","doi":"10.1227/neu.0000000000003213","DOIUrl":"10.1227/neu.0000000000003213","url":null,"abstract":"<p><strong>Background and objectives: </strong>The most common treatment of hydrocephalus is ventriculoperitoneal (VP) shunting. Peritoneal access is commonly conducted through an open laparotomy, but laparoscopic peritoneal access is gaining popularity. Many studies have reported the benefits of minimally invasive laparoscopic peritoneal access, but there is no consensus on its use. We conducted a systematic review and meta-analysis to compare open laparotomy vs laparoscopic peritoneal access in VP shunting.</p><p><strong>Methods: </strong>A systematic search was conducted in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines using 3 databases. Twelve studies included only adults, 3 included only pediatric patients, and 3 included both adults and pediatric patients.</p><p><strong>Results: </strong>Compared with open laparotomy, laparoscopic peritoneal access was associated with a reduction in distal shunt failure (6.1% vs 2.2%, P = .01), operative time (69.4 vs 56.3 minutes, P < .001), and length of stay (LOS) (9.6 vs 7.3 days, P < .001). There were no differences in proximal shunt failure, total shunt failure, intraoperative complications, or infection rate. In the pediatric population, laparoscopic access was associated with a reduced LOS (7.8 vs 5.9 days, P < .001). Heterogeneity was high but explained by the varying study populations and techniques.</p><p><strong>Conclusion: </strong>Laparoscopic peritoneal access for VP shunt insertion is associated with improved outcomes, including reduced distal shunt failure, reduced operative time, and reduced hospital LOS, when compared with open laparotomy and should be considered for shunt insertion. Additional studies are necessary to further determine the benefit of laparoscopic access, especially in the pediatric population.</p>","PeriodicalId":19276,"journal":{"name":"Neurosurgery","volume":" ","pages":"734-743"},"PeriodicalIF":3.9,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142504923","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Commentary: Is It Justified to Sacrifice the Pituitary Stalk During Craniopharyngioma Surgery? A Systematic Review and Meta-Analysis. 评论:在颅咽管瘤手术中牺牲垂体柄是否合理?系统回顾与元分析。
IF 3.9 2区 医学
Neurosurgery Pub Date : 2025-04-01 Epub Date: 2024-11-14 DOI: 10.1227/neu.0000000000003287
Hussam Abou-Al-Shaar, Georgios A Zenonos, Juan C Fernandez-Miranda, Paul A Gardner
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