NeurospinePub Date : 2025-03-01Epub Date: 2025-03-31DOI: 10.14245/ns.2449070.535
Young-Seok Lee, Myeong Jin Ko, Seung Won Park
{"title":"Incidence and Risk Factors of Postoperative Ileus in Oblique Lumbar Interbody Fusion Surgery: A Retrospective Study.","authors":"Young-Seok Lee, Myeong Jin Ko, Seung Won Park","doi":"10.14245/ns.2449070.535","DOIUrl":"https://doi.org/10.14245/ns.2449070.535","url":null,"abstract":"<p><strong>Purpose: </strong>Postoperative ileus (POI) typically occurs after abdominal surgery but can also affect patients undergoing spinal surgery via the lateral retroperitoneal approach, such as oblique lumbar interbody fusion (OLIF). Therefore, this study aimed to investigate the incidence and risk factors associated with POI in OLIF.</p><p><strong>Methods: </strong>This retrospective study examined a cohort of 465 patients who underwent OLIF from 2015 to 2023. Patient demographics, comorbidities, pre- and postoperative laboratory test results, and perioperative status were assessed. General condition of patients was assessed using the modified frailty index-11 (mFI-11), prognostic nutrition index, and geriatric nutrition risk index. In OLIF, the size and location of the psoas muscle involved in retraction and its relationship with the vertebral body were also investigated.</p><p><strong>Results: </strong>POI occurred in 19 patients (4%). Lower mFI-11 was linked to a higher risk of POI. While psoas muscle size had no significant effect on the risk of POI, the anterior location of the psoas muscle relative to the vertebral body was associated with a higher occurrence of POI. Multivariate logistic regression analysis of POI identified mFI-11 as the most significant risk factor (p = 0.003).</p><p><strong>Conclusion: </strong>This study demonstrated that frailty and nutritional status can influence the occurrence of POI after OLIF. Additionally, bowel manipulation associated with the location of psoas muscle and vertebral body was identified as a risk factor. Proper assessment and improvement in patient frailty and nutritional status before surgery can help predict and prevent the occurrence of postoperative POI.</p>","PeriodicalId":19269,"journal":{"name":"Neurospine","volume":"22 1","pages":"222-230"},"PeriodicalIF":3.8,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12010860/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144012260","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
NeurospinePub Date : 2025-03-01Epub Date: 2025-03-31DOI: 10.14245/ns.2550328.164
Alexander E Ropper
{"title":"Open Versus Minimally Invasive Spine Surgery Remains a Global Question - A Commentary on \"Open Versus Minimally Invasive Spine Surgery in the Treatment of Single-Level Degenerative Lumbar Spondylolisthesis: An AO Spine Global Cross-Sectional Study\".","authors":"Alexander E Ropper","doi":"10.14245/ns.2550328.164","DOIUrl":"https://doi.org/10.14245/ns.2550328.164","url":null,"abstract":"","PeriodicalId":19269,"journal":{"name":"Neurospine","volume":"22 1","pages":"48-50"},"PeriodicalIF":3.8,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12010859/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144008606","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
NeurospinePub Date : 2025-03-01Epub Date: 2024-12-22DOI: 10.14245/ns.2448682.341
Guoyan Liang, Tianying Liao, Yongyu Ye, Yi Cai, Junying Chen, Yunbing Chang
{"title":"Hand Dexterity Recovery Capacity for Degenerative Cervical Myelopathy With Varying Levels of Impairment: A Prospective 1-Year Follow-up Study.","authors":"Guoyan Liang, Tianying Liao, Yongyu Ye, Yi Cai, Junying Chen, Yunbing Chang","doi":"10.14245/ns.2448682.341","DOIUrl":"10.14245/ns.2448682.341","url":null,"abstract":"<p><strong>Objective: </strong>This study aimed to elucidate the hand function recovery capacity of degenerative cervical myelopathy (DCM) patients with different severities of hand dexterity impairment.</p><p><strong>Methods: </strong>Hand functional outcome measures such as the 10-second grip and release (10s-G&R) test, modified Japanese Orthopaedic Association (mJOA) upper extremity score and Japanese Orthopaedic Association Cervical Myelopathy Evaluation Questionnaire (JOACMEQ) upper extremity function were collected before surgery and at the 1-year follow-up. A total of 102 DCM patients were categorized into mild, moderate and severe group based on the preoperative 10s-G&R test result. Hand functional parameters were compared across the 3 groups. Multivariate linear regression was conducted to explore predictive factors. Receiver operating characteristic curve analysis was performed to assess the predictive efficacy of the preoperative 10s-G&R test and establish the cutoff value for incomplete recovery of hand dexterity.</p><p><strong>Results: </strong>At the 1-year follow-up, significant improvements were observed in all hand functional parameters across all 3 groups. However, the incomplete recovery rates of the mild, moderate, severe groups were 26.67%, 46.88%, and 57.50%, respectively (p < 0.05). Multivariate regression revealed that preoperative 10s-G&R test result, age, Hoffmann sign, duration of symptom, and mJOA Upper score serve as significant predictors for postoperative 10s-G&R test outcomes. Patients with a preoperative 10s-G&R test < 15 cycles have a 1.9 times higher risk of incomplete recovery of hand function (p = 0.005).</p><p><strong>Conclusion: </strong>Most patients, regardless of their preoperative hand function, exhibit potential for improvement in hand dexterity. However, worse initial hand dexterity correlates with poorer outcomes. Surgical treatment is recommended before the 10s-G&R test drops below 15 cycles.</p>","PeriodicalId":19269,"journal":{"name":"Neurospine","volume":" ","pages":"202-210"},"PeriodicalIF":3.8,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12010846/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142915426","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
NeurospinePub Date : 2025-03-01Epub Date: 2025-03-31DOI: 10.14245/ns.2448846.423
Siyuan Qin, Ruomu Qu, Ke Liu, Ruixin Yan, Weili Zhao, Jun Xu, Enlong Zhang, Feifei Zhou, Ning Lang
{"title":"Predicting Postoperative Progression of Ossification of the Posterior Longitudinal Ligament in the Cervical Spine Using Interpretable Radiomics Models.","authors":"Siyuan Qin, Ruomu Qu, Ke Liu, Ruixin Yan, Weili Zhao, Jun Xu, Enlong Zhang, Feifei Zhou, Ning Lang","doi":"10.14245/ns.2448846.423","DOIUrl":"https://doi.org/10.14245/ns.2448846.423","url":null,"abstract":"<p><strong>Objective: </strong>This study investigates the potential of radiomics to predict postoperative progression of ossification of the posterior longitudinal ligament (OPLL) after posterior cervical spine surgery.</p><p><strong>Methods: </strong>This retrospective study included 473 patients diagnosed with OPLL at Peking University Third Hospital between October 2006 and September 2022. Patients underwent posterior spinal surgery and had at least 2 computed tomography (CT) examinations spaced at least 1 year apart. OPLL progression was defined as an annual growth rate exceeding 7.5%. Radiomic features were extracted from preoperative CT images of the OPLL lesions, followed by feature selection using correlation coefficient analysis and least absolute shrinkage and selection operator, and dimensionality reduction using principal component analysis. Univariable analysis identified significant clinical variables for constructing the clinical model. Logistic regression models, including the Rad-score model, clinical model, and combined model, were developed to predict OPLL progression.</p><p><strong>Results: </strong>Of the 473 patients, 191 (40.4%) experienced OPLL progression. On the testing set, the combined model, which incorporated the Rad-score and clinical variables (area under the receiver operating characteristic curve [AUC] = 0.751), outperformed both the radiomics-only model (AUC = 0.693) and the clinical model (AUC = 0.620). Calibration curves demonstrated good agreement between predicted probabilities and observed outcomes, and decision curve analysis confirmed the clinical utility of the combined model. SHAP (SHapley Additive exPlanations) analysis indicated that the Rad-score and age were key contributors to the model's predictions, enhancing clinical interpretability.</p><p><strong>Conclusion: </strong>Radiomics, combined with clinical variables, provides a valuable predictive tool for assessing the risk of postoperative progression in cervical OPLL, supporting more personalized treatment strategies. Prospective, multicenter validation is needed to confirm the utility of the model in broader clinical settings.</p>","PeriodicalId":19269,"journal":{"name":"Neurospine","volume":"22 1","pages":"144-156"},"PeriodicalIF":3.8,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12010848/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144032699","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
NeurospinePub Date : 2025-03-01Epub Date: 2025-03-31DOI: 10.14245/ns.2449364.682
Yam Wa Man, Jedidiah Yui Shing Lui, Chor Yin Lam, Jason Pui Yin Cheung, Prudence Wing Hang Cheung
{"title":"Prevalence and Risk Factors for Postoperative Neurological Complications in Spinal Deformity Surgery: A Systematic Review and Proportional Meta-Analysis.","authors":"Yam Wa Man, Jedidiah Yui Shing Lui, Chor Yin Lam, Jason Pui Yin Cheung, Prudence Wing Hang Cheung","doi":"10.14245/ns.2449364.682","DOIUrl":"https://doi.org/10.14245/ns.2449364.682","url":null,"abstract":"<p><strong>Objective: </strong>To investigate the incidence of postoperative neurological complications among patients who underwent spinal deformity surgery and to determine the significant risk factors for postoperative neurological complications.</p><p><strong>Methods: </strong>Six databases PubMed, Web of Science, Scopus, MEDLINE, Embase, and Cochrane Library have been searched to identify observational studies from inception until January 2025. Inclusion criteria were patients aged ≥10 years with postoperative neurological complications after spinal deformity surgery. Stata/MP18.0 was used to conduct the meta-analysis in this review. The summary incidence estimates, proportion with 95% confidence intervals (CIs) and weights were pooled by the random-effects restricted maximum likelihood model.</p><p><strong>Results: </strong>The search strategy identified 53 articles with 40,958 patients for final review. Overall incidence of postoperative neurological complications was 7% (95% CI, 5.0%-9.0%; p < 0.001; I2 = 98.34%) in which incidence estimates for patients with adult spinal deformity and underwent 3-column spinal osteotomies were 12% (95% CI, 9%-16%; p < 0.001; I2 = 93.17%) and 18% (95% CI, 8%-31%; p < 0.001; I2 = 94.68%) respectively. Preoperative neurological deficit was the risk factor with highest overall odds ratio (OR, 2.86; 95% CI, 1.85-4.41; p = 0.01; I2 = 76.20%), followed by the presence of kyphosis (OR, 1.13; 95% CI, 0.75-1.70; p = 0.02; I2 = 81.80%) and age at surgery (OR, 1.04; 95% CI, 1.01-1.08; p = 0.04; I2 = 68.80%).</p><p><strong>Conclusion: </strong>Preoperative neurological deficit, the presence of kyphosis and age at surgery were significant risk factors for postoperative neurological complications. Therefore, comprehensive preoperative assessment and surgical planning are crucial to minimize the risk of developing postoperative neurological complications or the deterioration of pre-existing neurologic deficits.</p>","PeriodicalId":19269,"journal":{"name":"Neurospine","volume":"22 1","pages":"243-263"},"PeriodicalIF":3.8,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12010854/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144030141","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
NeurospinePub Date : 2025-03-01Epub Date: 2025-03-31DOI: 10.14245/ns.2449334.667
Dong Li, Xin Sun, Jie Li, Yanjie Xu, Yong Qiu, Zezhang Zhu, Zhen Liu
{"title":"Does Vertebral Cement Augmentation Reduce Postoperative Proximal Junction Complications in Spinal Deformity Corrective Surgery: A Systematic Review and Meta-analysis.","authors":"Dong Li, Xin Sun, Jie Li, Yanjie Xu, Yong Qiu, Zezhang Zhu, Zhen Liu","doi":"10.14245/ns.2449334.667","DOIUrl":"https://doi.org/10.14245/ns.2449334.667","url":null,"abstract":"<p><strong>Objective: </strong>To assess the effectiveness of vertebral cement augmentation (VCA) at upper instrumented vertebra (UIV) and UIV+1 in preventing proximal junction complications in correction surgery for adult spinal deformity patients.</p><p><strong>Methods: </strong>A literature search was conducted on Web of Science, PubMed, and Cochrane Library databases for comparative studies published before December 30th, 2024. Two reviewers independently screened eligible articles based on the inclusion and exclusion criteria, assessed study quality with Newcastle-Ottawa scale, and extracted data like study characteristics, surgical details, primary and secondary outcomes. Data analysis was performed using Review Manager 5.4 and Stata software.</p><p><strong>Results: </strong>Of all 513 papers screened, a meta-analysis was conducted on 7 articles, which included 333 cases in the VCA group and 827 cases in the control group. Patients in the VCA group had significantly older age and lower T score than patients in the control group. Although there was no statistically significant difference in the incidence of proximal junctional failure between the 2 groups, the results of the meta-analysis showed that the incidence of proximal junctional failure and the need for revision surgery were reduced by 36% and 71%, respectively, in the VCA group. One study reported 2 clinically silent pulmonary cement embolism and 1 patient requiring surgical decompression for cement leak into the spinal canal.</p><p><strong>Conclusion: </strong>This meta-analysis supported the use of VCA in corrective surgery for spinal deformities patients, especially in patients with advanced age and osteoporosis.</p>","PeriodicalId":19269,"journal":{"name":"Neurospine","volume":"22 1","pages":"51-66"},"PeriodicalIF":3.8,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12010840/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144033893","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
NeurospinePub Date : 2025-03-01Epub Date: 2025-03-31DOI: 10.14245/ns.2448794.397
Xin Wang, Tao Hu, Chaofan Qin, Bo Lei, Mingxin Chen, Ke Ma, Qingyan Long, Qingshuai Yu, Si Cheng, Zhengjian Yan
{"title":"Anatomical Importance Between Neural Structure and Bony Landmark in Neuroventral Decompression for Posterior Endoscopic Cervical Discectomy.","authors":"Xin Wang, Tao Hu, Chaofan Qin, Bo Lei, Mingxin Chen, Ke Ma, Qingyan Long, Qingshuai Yu, Si Cheng, Zhengjian Yan","doi":"10.14245/ns.2448794.397","DOIUrl":"https://doi.org/10.14245/ns.2448794.397","url":null,"abstract":"<p><strong>Objective: </strong>This study aims to investigate the anatomical relationship among the nerve roots, intervertebral space, pedicles, and intradural rootlets of the cervical spine for improving operative outcomes and exploring neuroventral decompression approach in posterior endoscopic cervical discectomy (PECD).</p><p><strong>Methods: </strong>Cervical computed tomography myelography imaging data from January 2021 to May 2023 were collected, and the RadiAnt DICOM Viewer Software was employed to conduct multiplane reconstruction. The following parameters were recorded: width of nerve root (WN), nerve root-superior pedicle distance (NSPD), nerve root-inferior pedicle distance (NIPD), and the relationship between the intervertebral space and the nerve root (shoulder, anterior, and axillary). Additionally, the descending angles between the spinal cord and the ventral (VRA) and dorsal (DRA) rootlets were measured.</p><p><strong>Results: </strong>The WN showed a gradual increase from C4 to C7, with measurements notably larger in men compared to women. The NSPD decreased gradually from the C2-3 to the C5-6 levels. However, the NIPD showed an opposite level-related change, notably larger than the NSPD at the C4-5, C5-6, and C7-T1 levels. Furthermore, significant differences in NIPD were observed between different age groups and genders. The incidence of the anterior type exhibited a gradual decrease from the C2-3 to the C5-6 levels. Conversely, the axillary type exhibited an opposite level-related change. Additionally, the VRA and DRA decreased as the level descended, with measurements significantly larger in females.</p><p><strong>Conclusion: </strong>A prediction of the positional relationship between the intervertebral space and the nerve root is essential for the direct neuroventral decompression in PECD to avoid damaging the neural structures. The axillary route of the nerve root offers a safer and more effective pathway for performing direct neuroventral decompression compared to the shoulder approach.</p>","PeriodicalId":19269,"journal":{"name":"Neurospine","volume":"22 1","pages":"286-296"},"PeriodicalIF":3.8,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12010839/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144028922","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
NeurospinePub Date : 2025-03-01Epub Date: 2025-03-31DOI: 10.14245/ns.2550096.048
Tomoyuki Asada, Eric R Zhao, Adin M Ehrlich, Adrian Lui, Andrea Pezzi, Sereen Halayqeh, Tarek Harhash, Olivia C Tuma, Kasra Araghi, Todd J Albert, James Farmer, Russel C Huang, Harvinder Sandhu, Han Jo Kim, Francis C Lovecchio, James E Dowdell, Sravisht Iyer, Sheeraz A Qureshi
{"title":"Distinct Recovery Patterns After Transforaminal Lumbar Interbody Fusion: Comparing Minimally Invasive and Open Approaches Using Mixed-Effects Segmented Regression.","authors":"Tomoyuki Asada, Eric R Zhao, Adin M Ehrlich, Adrian Lui, Andrea Pezzi, Sereen Halayqeh, Tarek Harhash, Olivia C Tuma, Kasra Araghi, Todd J Albert, James Farmer, Russel C Huang, Harvinder Sandhu, Han Jo Kim, Francis C Lovecchio, James E Dowdell, Sravisht Iyer, Sheeraz A Qureshi","doi":"10.14245/ns.2550096.048","DOIUrl":"https://doi.org/10.14245/ns.2550096.048","url":null,"abstract":"<p><strong>Objective: </strong>While minimally invasive-transforaminal lumbar interbody fusion (MIS-TLIF) has shown superiority in key clinical metrics over the open approach, evidence regarding patient-reported outcomes remains limited. This study compared postoperative recovery trajectories and symptomatic improvement phases between MIS and open TLIF.</p><p><strong>Methods: </strong>This retrospective review included patients who underwent single-level MIS or open TLIF. Oswestry Disability Index (ODI) and Numerical Rating Scale (NRS) for back and leg pain were collected preoperatively and postoperatively. Segmented regression analysis with mixed-effects modeling, allowing for identification of distinct recovery phases, compared symptomatic trends between approaches.</p><p><strong>Results: </strong>Of 324 patients (268 MIS, 56 open), baseline demographics were similar except for greater preoperative leg pain in the MIS group (NRS: 6.0 vs. 5.0, p = 0.027). A segmented regression model identified 4 ODI recovery phases: postoperative disability phase (PDP, day 0 to 13), early improvement phase (day 13 to 28), late improvement phase (day 28 to 110), and plateau phase (later than day 110). The MIS group exhibited significantly lower disability exacerbation during PDP (β = 0.93 vs. 1.42 points per day, p = 0.008). Additionally, the plateau of NRS back occurred significantly earlier in the MIS group than in the open group (MIS, 26.7 ± 2.6 days vs. open, 51.7 ± 6.6 days, p < 0.001).</p><p><strong>Conclusion: </strong>MIS-TLIF resulted in lower postoperative disability during the first 2 weeks compared to the open approach. Furthermore, low back pain achieved an earlier plateau in back pain by about 4 weeks in the MIS approach.</p>","PeriodicalId":19269,"journal":{"name":"Neurospine","volume":"22 1","pages":"3-13"},"PeriodicalIF":3.8,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12010849/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144012532","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
NeurospinePub Date : 2025-03-01Epub Date: 2025-03-31DOI: 10.14245/ns.2448990.495
Tien Tran, Ian M Singleton, Victor Ungurean, Andrea Rowland, Anna Martin, Oluwatodimu Richard Raji, Dimitriy G Kondrashov
{"title":"Loss of Mass and Surface Topography in 3-Dimensional-Printed Solid Titanium Cages Upon Impaction: An In Vitro Model.","authors":"Tien Tran, Ian M Singleton, Victor Ungurean, Andrea Rowland, Anna Martin, Oluwatodimu Richard Raji, Dimitriy G Kondrashov","doi":"10.14245/ns.2448990.495","DOIUrl":"https://doi.org/10.14245/ns.2448990.495","url":null,"abstract":"<p><strong>Objective: </strong>There is increased use of 3-dimensional (3D)-printing for manufacturing of interbody cages to create microscale surface features that promote bone formation. Those features may be vulnerable to abrasion and/or delamination during cage impaction. Our objective was to quantify loss of mass and changes in surface topography of 3D-printed titanium interbody cages due to surgical impaction.</p><p><strong>Methods: </strong>Eight surfaces of four 3D-printed titanium modular interbody fusion cages were tested. The cages were impacted into the Sawbones model with compression preload of either 200N or 400N using a guided 1-lb (0.45 kg) drop weight. Mass and surface roughness parameters of each endplate were recorded and compared for differences.</p><p><strong>Results: </strong>Significant weight loss was observed for the superior endplate group and for both 200N and 400N preloads. For pooled data comparison, significant postimpaction decreases were observed for mean roughness, root-mean-squared roughness, mean roughness depth, and total height of roughness profile. No significant differences were observed for profile skewness and kurtosis. There were significant changes in almost all roughness parameters in the anterior region of the cage postimpaction with significant changes in 2 out of 6 parameters in the middle, posterior, and central regions postimpaction.</p><p><strong>Conclusion: </strong>Three-dimensional-printed titanium interbody fusion cages underwent loss of mass and alteration in surface topography during benchtop testing replicating physiologic conditions. There was an endplate- and region-specific postimpaction change in roughness parameters. The anterior surface experienced the largest change in surface parameters postimpaction. Our results have implications for future cage design and pre-approval testing of 3D-printed implants.</p>","PeriodicalId":19269,"journal":{"name":"Neurospine","volume":"22 1","pages":"173-184"},"PeriodicalIF":3.8,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12010865/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144029948","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
NeurospinePub Date : 2025-03-01Epub Date: 2025-03-31DOI: 10.14245/ns.2550266.133
Byung Ho Lee, Jae Won Shin
{"title":"A Commentary on \"Does Vertebral Cement Augmentation Reduce Postoperative Proximal Junction Complications in Spinal Deformity Corrective Surgery: A Systematic Review and Meta-analysis\".","authors":"Byung Ho Lee, Jae Won Shin","doi":"10.14245/ns.2550266.133","DOIUrl":"https://doi.org/10.14245/ns.2550266.133","url":null,"abstract":"","PeriodicalId":19269,"journal":{"name":"Neurospine","volume":"22 1","pages":"67-68"},"PeriodicalIF":3.8,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12010856/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144011836","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}